PL2015759T3 - Terapia skojarzona - Google Patents

Terapia skojarzona

Info

Publication number: PL2015759T3
Authority: PL; Poland
Prior art keywords: alovudine; zidovudine; administration; molar ratio; combination therapy
Prior art date: 2006-05-05

Application number

PL07735778T

Other languages

English (en)

Polish (pl)

Inventor

Hong Zhang

Bo Oberg

Original Assignee

Medivir Ab

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2006-05-05

Filing date

2007-05-04

Publication date

2011-01-31

2007-05-04 Application filed by Medivir Ab filed Critical Medivir Ab

2011-01-31 Publication of PL2015759T3 publication Critical patent/PL2015759T3/pl

Links

238000002648 combination therapy Methods 0.000 title 1
UXCAQJAQSWSNPQ-XLPZGREQSA-N Alovudine Chemical compound O=C1NC(=O)C(C)=CN1[C@@H]1O[C@H](CO)[C@@H](F)C1 UXCAQJAQSWSNPQ-XLPZGREQSA-N 0.000 abstract 4
229950004424 alovudine Drugs 0.000 abstract 4
HBOMLICNUCNMMY-XLPZGREQSA-N zidovudine Chemical compound O=C1NC(=O)C(C)=CN1[C@@H]1O[C@H](CO)[C@@H](N=[N+]=[N-])C1 HBOMLICNUCNMMY-XLPZGREQSA-N 0.000 abstract 3
229960002555 zidovudine Drugs 0.000 abstract 3
206010059396 Mitochondrial DNA depletion Diseases 0.000 abstract 1
206010053961 Mitochondrial toxicity Diseases 0.000 abstract 1
238000011260 co-administration Methods 0.000 abstract 1
238000000034 method Methods 0.000 abstract 1
231100000296 mitochondrial toxicity Toxicity 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1
238000011321 prophylaxis Methods 0.000 abstract 1
238000011282 treatment Methods 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
- A61K31/7068—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
- A61K31/7072—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid having two oxo groups directly attached to the pyrimidine ring, e.g. uridine, uridylic acid, thymidine, zidovudine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T428/00—Stock material or miscellaneous articles
- Y10T428/31504—Composite [nonstructural laminate]
- Y10T428/31678—Of metal
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T428/00—Stock material or miscellaneous articles
- Y10T428/31504—Composite [nonstructural laminate]
- Y10T428/31855—Of addition polymer from unsaturated monomers

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Chemical & Material Sciences (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
Epidemiology (AREA)
Molecular Biology (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Virology (AREA)
Chemical Kinetics & Catalysis (AREA)
AIDS & HIV (AREA)
Engineering & Computer Science (AREA)
Tropical Medicine & Parasitology (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Iron Core Of Rotating Electric Machines (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Saccharide Compounds (AREA)

PL07735778T 2006-05-05 2007-05-04 Terapia skojarzona PL2015759T3 (pl)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
GBGB0608876.9A GB0608876D0 (en)	2006-05-05	2006-05-05	Combination therapy
PCT/IB2007/051688 WO2007129274A2 (fr)	2006-05-05	2007-05-04	Thérapie en combinaison
EP07735778A EP2015759B1 (fr)	2006-05-05	2007-05-04	Thérapie en combinaison

Publications (1)

Publication Number	Publication Date
PL2015759T3 true PL2015759T3 (pl)	2011-01-31

Family

ID=36603961

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PL07735778T PL2015759T3 (pl)	2006-05-05	2007-05-04	Terapia skojarzona

Country Status (19)

Country	Link
US (3)	US20090170806A1 (fr)
EP (1)	EP2015759B1 (fr)
JP (1)	JP2009536192A (fr)
CN (1)	CN101437525B (fr)
AT (1)	ATE476187T1 (fr)
AU (1)	AU2007246644B2 (fr)
BR (1)	BRPI0710730A2 (fr)
CA (1)	CA2651232C (fr)
DE (1)	DE602007008226D1 (fr)
DK (1)	DK2015759T3 (fr)
EA (1)	EA014778B1 (fr)
ES (1)	ES2349486T3 (fr)
GB (1)	GB0608876D0 (fr)
HK (1)	HK1132651A1 (fr)
MX (1)	MX2008013491A (fr)
PL (1)	PL2015759T3 (fr)
PT (1)	PT2015759E (fr)
WO (1)	WO2007129274A2 (fr)
ZA (1)	ZA200809110B (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2013119193A2 (fr) *	2010-10-21	2013-08-15	Tufts University	Dépistage et traitement basés sur les mitochondries extracellulaires

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5223263A (en)	1988-07-07	1993-06-29	Vical, Inc.	Liponucleotide-containing liposomes
SE464168B (sv) *	1989-07-19	1991-03-18	Bo Fredrik Oeberg	Antiviral komposition bestaaende av en 3'-fluoro-2',3'-dideoxynukleosidfoerening och en 2',3'-dideoxynukleosidfoerening (exempelvis azt)
DE69128626T2 (de) *	1990-07-19	1998-05-20	The Wellcome Foundation Ltd., Greenford	Enzyminaktivatoren
EP0470355B1 (fr)	1990-08-06	1996-06-05	American Cyanamid Company	Procédé de production de déoxynucléosides
DE4026265A1 (de) *	1990-08-20	1992-02-27	Boehringer Mannheim Gmbh	Neue phospholipid-derivate von nucleosiden, deren herstellung sowie deren verwendung als antivirale arzneimittel
EP0698032B1 (fr)	1993-05-12	1998-07-29	Rhodia Limited	Preparation de fluoro-nucleosides et intermediaires pour ce faire
DE4402492A1 (de)	1994-01-28	1995-08-03	Boehringer Mannheim Gmbh	Verfahren zur Herstellung von unsymmetrischen Phosphorsäurediestern
DE4418690A1 (de)	1994-05-28	1996-01-11	Boehringer Mannheim Gmbh	Neue Lipidester von Nucleosid-Monophosphaten und deren Verwendung als immunsuppressive Arzneimittel
JP2002502826A (ja) *	1998-02-09	2002-01-29	アヴェンティスファーマシューティカルズプロダクツインコーポレイテッド	Ｈｉｖ感染の治療用組成物および方法
SE0100733D0 (sv) *	2001-03-05	2001-03-05	Medivir Ab	Non-nucleoside reverse transcriptase inhibitors
BR0311141A (pt)	2002-06-27	2005-06-07	Medivir Ab	Interação sinergìstica de abacavir e alovudine
EP1610782A1 (fr) *	2003-03-27	2006-01-04	Boehringer Ingelheim International GmbH	Combinaison antivirale d'une dipyridodiazepinone et compose antiretroviral
DE602004024584D1 (de) *	2004-01-08	2010-01-21	Medivir Ab	Inhibitoren der nicht-nukleotidischen reversen transkriptase

2006
- 2006-05-05 GB GBGB0608876.9A patent/GB0608876D0/en not_active Ceased
2007
- 2007-05-04 US US12/299,466 patent/US20090170806A1/en not_active Abandoned
- 2007-05-04 JP JP2009508627A patent/JP2009536192A/ja active Pending
- 2007-05-04 PT PT07735778T patent/PT2015759E/pt unknown
- 2007-05-04 EP EP07735778A patent/EP2015759B1/fr active Active
- 2007-05-04 AU AU2007246644A patent/AU2007246644B2/en not_active Ceased
- 2007-05-04 CN CN2007800163168A patent/CN101437525B/zh not_active Expired - Fee Related
- 2007-05-04 AT AT07735778T patent/ATE476187T1/de not_active IP Right Cessation
- 2007-05-04 DK DK07735778.8T patent/DK2015759T3/da active
- 2007-05-04 WO PCT/IB2007/051688 patent/WO2007129274A2/fr active Application Filing
- 2007-05-04 DE DE602007008226T patent/DE602007008226D1/de active Active
- 2007-05-04 EA EA200870501A patent/EA014778B1/ru not_active IP Right Cessation
- 2007-05-04 PL PL07735778T patent/PL2015759T3/pl unknown
- 2007-05-04 CA CA2651232A patent/CA2651232C/fr not_active Expired - Fee Related
- 2007-05-04 BR BRPI0710730-7A patent/BRPI0710730A2/pt not_active IP Right Cessation
- 2007-05-04 ES ES07735778T patent/ES2349486T3/es active Active
- 2007-05-04 MX MX2008013491A patent/MX2008013491A/es active IP Right Grant
2008
- 2008-10-23 ZA ZA200809110A patent/ZA200809110B/xx unknown
2009
- 2009-11-05 HK HK09110318.5A patent/HK1132651A1/xx not_active IP Right Cessation
2012
- 2012-01-17 US US13/352,156 patent/US20120115807A1/en not_active Abandoned
2013
- 2013-02-01 US US13/757,732 patent/US20130217646A1/en not_active Abandoned

Also Published As

Publication number	Publication date
PT2015759E (pt)	2010-10-28
ZA200809110B (en)	2009-08-26
WO2007129274A2 (fr)	2007-11-15
CN101437525A (zh)	2009-05-20
WO2007129274A9 (fr)	2009-03-12
DE602007008226D1 (de)	2010-09-16
CN101437525B (zh)	2011-11-23
EA200870501A1 (ru)	2009-04-28
EA014778B1 (ru)	2011-02-28
US20090170806A1 (en)	2009-07-02
HK1132651A1 (en)	2010-03-05
DK2015759T3 (da)	2010-11-15
ES2349486T3 (es)	2011-01-04
AU2007246644A1 (en)	2007-11-15
WO2007129274A3 (fr)	2008-03-06
EP2015759B1 (fr)	2010-08-04
EP2015759A2 (fr)	2009-01-21
JP2009536192A (ja)	2009-10-08
BRPI0710730A2 (pt)	2012-03-13
ATE476187T1 (de)	2010-08-15
MX2008013491A (es)	2008-10-29
US20120115807A1 (en)	2012-05-10
US20130217646A1 (en)	2013-08-22
CA2651232A1 (fr)	2007-11-15
AU2007246644B2 (en)	2010-09-30
GB0608876D0 (en)	2006-06-14
CA2651232C (fr)	2013-12-31

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