PL2015759T3 - Terapia skojarzona - Google Patents
Terapia skojarzonaInfo
- Publication number
- PL2015759T3 PL2015759T3 PL07735778T PL07735778T PL2015759T3 PL 2015759 T3 PL2015759 T3 PL 2015759T3 PL 07735778 T PL07735778 T PL 07735778T PL 07735778 T PL07735778 T PL 07735778T PL 2015759 T3 PL2015759 T3 PL 2015759T3
- Authority
- PL
- Poland
- Prior art keywords
- alovudine
- zidovudine
- administration
- molar ratio
- combination therapy
- Prior art date
Links
- 238000002648 combination therapy Methods 0.000 title 1
- UXCAQJAQSWSNPQ-XLPZGREQSA-N Alovudine Chemical compound O=C1NC(=O)C(C)=CN1[C@@H]1O[C@H](CO)[C@@H](F)C1 UXCAQJAQSWSNPQ-XLPZGREQSA-N 0.000 abstract 4
- 229950004424 alovudine Drugs 0.000 abstract 4
- HBOMLICNUCNMMY-XLPZGREQSA-N zidovudine Chemical compound O=C1NC(=O)C(C)=CN1[C@@H]1O[C@H](CO)[C@@H](N=[N+]=[N-])C1 HBOMLICNUCNMMY-XLPZGREQSA-N 0.000 abstract 3
- 229960002555 zidovudine Drugs 0.000 abstract 3
- 206010059396 Mitochondrial DNA depletion Diseases 0.000 abstract 1
- 206010053961 Mitochondrial toxicity Diseases 0.000 abstract 1
- 238000011260 co-administration Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 231100000296 mitochondrial toxicity Toxicity 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 238000011321 prophylaxis Methods 0.000 abstract 1
- 238000011282 treatment Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
- A61K31/7068—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
- A61K31/7072—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid having two oxo groups directly attached to the pyrimidine ring, e.g. uridine, uridylic acid, thymidine, zidovudine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T428/00—Stock material or miscellaneous articles
- Y10T428/31504—Composite [nonstructural laminate]
- Y10T428/31678—Of metal
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T428/00—Stock material or miscellaneous articles
- Y10T428/31504—Composite [nonstructural laminate]
- Y10T428/31855—Of addition polymer from unsaturated monomers
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Virology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- AIDS & HIV (AREA)
- Engineering & Computer Science (AREA)
- Tropical Medicine & Parasitology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Iron Core Of Rotating Electric Machines (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB0608876.9A GB0608876D0 (en) | 2006-05-05 | 2006-05-05 | Combination therapy |
PCT/IB2007/051688 WO2007129274A2 (fr) | 2006-05-05 | 2007-05-04 | Thérapie en combinaison |
EP07735778A EP2015759B1 (fr) | 2006-05-05 | 2007-05-04 | Thérapie en combinaison |
Publications (1)
Publication Number | Publication Date |
---|---|
PL2015759T3 true PL2015759T3 (pl) | 2011-01-31 |
Family
ID=36603961
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PL07735778T PL2015759T3 (pl) | 2006-05-05 | 2007-05-04 | Terapia skojarzona |
Country Status (19)
Country | Link |
---|---|
US (3) | US20090170806A1 (fr) |
EP (1) | EP2015759B1 (fr) |
JP (1) | JP2009536192A (fr) |
CN (1) | CN101437525B (fr) |
AT (1) | ATE476187T1 (fr) |
AU (1) | AU2007246644B2 (fr) |
BR (1) | BRPI0710730A2 (fr) |
CA (1) | CA2651232C (fr) |
DE (1) | DE602007008226D1 (fr) |
DK (1) | DK2015759T3 (fr) |
EA (1) | EA014778B1 (fr) |
ES (1) | ES2349486T3 (fr) |
GB (1) | GB0608876D0 (fr) |
HK (1) | HK1132651A1 (fr) |
MX (1) | MX2008013491A (fr) |
PL (1) | PL2015759T3 (fr) |
PT (1) | PT2015759E (fr) |
WO (1) | WO2007129274A2 (fr) |
ZA (1) | ZA200809110B (fr) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2013119193A2 (fr) * | 2010-10-21 | 2013-08-15 | Tufts University | Dépistage et traitement basés sur les mitochondries extracellulaires |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5223263A (en) | 1988-07-07 | 1993-06-29 | Vical, Inc. | Liponucleotide-containing liposomes |
SE464168B (sv) * | 1989-07-19 | 1991-03-18 | Bo Fredrik Oeberg | Antiviral komposition bestaaende av en 3'-fluoro-2',3'-dideoxynukleosidfoerening och en 2',3'-dideoxynukleosidfoerening (exempelvis azt) |
DE69128626T2 (de) * | 1990-07-19 | 1998-05-20 | The Wellcome Foundation Ltd., Greenford | Enzyminaktivatoren |
EP0470355B1 (fr) | 1990-08-06 | 1996-06-05 | American Cyanamid Company | Procédé de production de déoxynucléosides |
DE4026265A1 (de) * | 1990-08-20 | 1992-02-27 | Boehringer Mannheim Gmbh | Neue phospholipid-derivate von nucleosiden, deren herstellung sowie deren verwendung als antivirale arzneimittel |
EP0698032B1 (fr) | 1993-05-12 | 1998-07-29 | Rhodia Limited | Preparation de fluoro-nucleosides et intermediaires pour ce faire |
DE4402492A1 (de) | 1994-01-28 | 1995-08-03 | Boehringer Mannheim Gmbh | Verfahren zur Herstellung von unsymmetrischen Phosphorsäurediestern |
DE4418690A1 (de) | 1994-05-28 | 1996-01-11 | Boehringer Mannheim Gmbh | Neue Lipidester von Nucleosid-Monophosphaten und deren Verwendung als immunsuppressive Arzneimittel |
JP2002502826A (ja) * | 1998-02-09 | 2002-01-29 | アヴェンティス ファーマシューティカルズ プロダクツ インコーポレイテッド | Hiv感染の治療用組成物および方法 |
SE0100733D0 (sv) * | 2001-03-05 | 2001-03-05 | Medivir Ab | Non-nucleoside reverse transcriptase inhibitors |
BR0311141A (pt) | 2002-06-27 | 2005-06-07 | Medivir Ab | Interação sinergìstica de abacavir e alovudine |
EP1610782A1 (fr) * | 2003-03-27 | 2006-01-04 | Boehringer Ingelheim International GmbH | Combinaison antivirale d'une dipyridodiazepinone et compose antiretroviral |
DE602004024584D1 (de) * | 2004-01-08 | 2010-01-21 | Medivir Ab | Inhibitoren der nicht-nukleotidischen reversen transkriptase |
-
2006
- 2006-05-05 GB GBGB0608876.9A patent/GB0608876D0/en not_active Ceased
-
2007
- 2007-05-04 US US12/299,466 patent/US20090170806A1/en not_active Abandoned
- 2007-05-04 JP JP2009508627A patent/JP2009536192A/ja active Pending
- 2007-05-04 PT PT07735778T patent/PT2015759E/pt unknown
- 2007-05-04 EP EP07735778A patent/EP2015759B1/fr active Active
- 2007-05-04 AU AU2007246644A patent/AU2007246644B2/en not_active Ceased
- 2007-05-04 CN CN2007800163168A patent/CN101437525B/zh not_active Expired - Fee Related
- 2007-05-04 AT AT07735778T patent/ATE476187T1/de not_active IP Right Cessation
- 2007-05-04 DK DK07735778.8T patent/DK2015759T3/da active
- 2007-05-04 WO PCT/IB2007/051688 patent/WO2007129274A2/fr active Application Filing
- 2007-05-04 DE DE602007008226T patent/DE602007008226D1/de active Active
- 2007-05-04 EA EA200870501A patent/EA014778B1/ru not_active IP Right Cessation
- 2007-05-04 PL PL07735778T patent/PL2015759T3/pl unknown
- 2007-05-04 CA CA2651232A patent/CA2651232C/fr not_active Expired - Fee Related
- 2007-05-04 BR BRPI0710730-7A patent/BRPI0710730A2/pt not_active IP Right Cessation
- 2007-05-04 ES ES07735778T patent/ES2349486T3/es active Active
- 2007-05-04 MX MX2008013491A patent/MX2008013491A/es active IP Right Grant
-
2008
- 2008-10-23 ZA ZA200809110A patent/ZA200809110B/xx unknown
-
2009
- 2009-11-05 HK HK09110318.5A patent/HK1132651A1/xx not_active IP Right Cessation
-
2012
- 2012-01-17 US US13/352,156 patent/US20120115807A1/en not_active Abandoned
-
2013
- 2013-02-01 US US13/757,732 patent/US20130217646A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
PT2015759E (pt) | 2010-10-28 |
ZA200809110B (en) | 2009-08-26 |
WO2007129274A2 (fr) | 2007-11-15 |
CN101437525A (zh) | 2009-05-20 |
WO2007129274A9 (fr) | 2009-03-12 |
DE602007008226D1 (de) | 2010-09-16 |
CN101437525B (zh) | 2011-11-23 |
EA200870501A1 (ru) | 2009-04-28 |
EA014778B1 (ru) | 2011-02-28 |
US20090170806A1 (en) | 2009-07-02 |
HK1132651A1 (en) | 2010-03-05 |
DK2015759T3 (da) | 2010-11-15 |
ES2349486T3 (es) | 2011-01-04 |
AU2007246644A1 (en) | 2007-11-15 |
WO2007129274A3 (fr) | 2008-03-06 |
EP2015759B1 (fr) | 2010-08-04 |
EP2015759A2 (fr) | 2009-01-21 |
JP2009536192A (ja) | 2009-10-08 |
BRPI0710730A2 (pt) | 2012-03-13 |
ATE476187T1 (de) | 2010-08-15 |
MX2008013491A (es) | 2008-10-29 |
US20120115807A1 (en) | 2012-05-10 |
US20130217646A1 (en) | 2013-08-22 |
CA2651232A1 (fr) | 2007-11-15 |
AU2007246644B2 (en) | 2010-09-30 |
GB0608876D0 (en) | 2006-06-14 |
CA2651232C (fr) | 2013-12-31 |
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