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PL1917253T3 - Sposób wytwarzania betamimetyków - Google Patents

Sposób wytwarzania betamimetyków

Info

Publication number
PL1917253T3
PL1917253T3 PL06778214T PL06778214T PL1917253T3 PL 1917253 T3 PL1917253 T3 PL 1917253T3 PL 06778214 T PL06778214 T PL 06778214T PL 06778214 T PL06778214 T PL 06778214T PL 1917253 T3 PL1917253 T3 PL 1917253T3
Authority
PL
Poland
Prior art keywords
betamimetics
producing
producing betamimetics
Prior art date
Application number
PL06778214T
Other languages
English (en)
Inventor
Thomas Krueger
Uwe Ries
Juergen Schnaubelt
Werner Rall
Zeno A Leuter
Adil Duran
Rainer Soyka
Original Assignee
Boehringer Ingelheim Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Int filed Critical Boehringer Ingelheim Int
Publication of PL1917253T3 publication Critical patent/PL1917253T3/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D265/00Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/281,4-Oxazines; Hydrogenated 1,4-oxazines
    • C07D265/341,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings
    • C07D265/361,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings condensed with one six-membered ring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C201/00Preparation of esters of nitric or nitrous acid or of compounds containing nitro or nitroso groups bound to a carbon skeleton
    • C07C201/06Preparation of nitro compounds
    • C07C201/08Preparation of nitro compounds by substitution of hydrogen atoms by nitro groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C221/00Preparation of compounds containing amino groups and doubly-bound oxygen atoms bound to the same carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00Carboxylic acid amides
    • C07C233/01Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/12Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by halogen atoms or by nitro or nitroso groups
    • C07C233/13Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by halogen atoms or by nitro or nitroso groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00Carboxylic acid amides
    • C07C233/01Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/16Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
    • C07C233/17Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
    • C07C233/18Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom having the carbon atom of the carboxamide group bound to a hydrogen atom or to a carbon atom of an acyclic saturated carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • C07C45/70Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form
    • C07C45/71Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form being hydroxy groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/76Ketones containing a keto group bound to a six-membered aromatic ring
    • C07C49/84Ketones containing a keto group bound to a six-membered aromatic ring containing ether groups, groups, groups, or groups
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pulmonology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Hydrogenated Pyridines (AREA)
PL06778214T 2005-08-15 2006-08-10 Sposób wytwarzania betamimetyków PL1917253T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP05107470 2005-08-15
EP06778214.4A EP1917253B1 (de) 2005-08-15 2006-08-10 Verfahren zur herstellung von betamimetika
PCT/EP2006/065217 WO2007020227A1 (de) 2005-08-15 2006-08-10 Verfahren zur herstellung von betamimetika

Publications (1)

Publication Number Publication Date
PL1917253T3 true PL1917253T3 (pl) 2015-06-30

Family

ID=37198936

Family Applications (1)

Application Number Title Priority Date Filing Date
PL06778214T PL1917253T3 (pl) 2005-08-15 2006-08-10 Sposób wytwarzania betamimetyków

Country Status (21)

Country Link
US (2) US20070088160A1 (pl)
EP (1) EP1917253B1 (pl)
JP (1) JP5270343B2 (pl)
KR (1) KR101360803B1 (pl)
CN (1) CN101208316B (pl)
AR (1) AR056456A1 (pl)
AU (1) AU2006281449B2 (pl)
BR (1) BRPI0614410A2 (pl)
CA (1) CA2619402C (pl)
DK (1) DK1917253T3 (pl)
ES (1) ES2530991T3 (pl)
IL (1) IL189460A (pl)
MX (1) MX2008001976A (pl)
NZ (1) NZ566577A (pl)
PE (1) PE20070418A1 (pl)
PL (1) PL1917253T3 (pl)
RU (1) RU2412176C2 (pl)
TW (1) TWI412523B (pl)
UY (1) UY29742A1 (pl)
WO (1) WO2007020227A1 (pl)
ZA (1) ZA200710049B (pl)

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US20050255050A1 (en) * 2004-05-14 2005-11-17 Boehringer Ingelheim International Gmbh Powder formulations for inhalation, comprising enantiomerically pure beta agonists
PL1917253T3 (pl) 2005-08-15 2015-06-30 Boehringer Ingelheim Int Sposób wytwarzania betamimetyków
PL2125759T3 (pl) * 2007-01-25 2011-12-30 Boehringer Ingelheim Int Sposób wytwarzania związków betamimetycznych
CN101704756B (zh) * 2009-11-20 2017-12-05 大连九信精细化工有限公司 1—(4—氟苯基)—2—甲基—2—丙胺的合成方法
WO2013113778A1 (en) 2012-02-03 2013-08-08 Basf Se Fungicidal pyrimidine compounds
EA201491472A1 (ru) 2012-02-03 2015-01-30 Басф Се Фунгицидные соединения пиримидина
WO2013113788A1 (en) 2012-02-03 2013-08-08 Basf Se Fungicidal pyrimidine compounds
WO2013113720A1 (en) 2012-02-03 2013-08-08 Basf Se Fungicidal pyrimidine compounds
WO2013113773A1 (en) 2012-02-03 2013-08-08 Basf Se Fungicidal pyrimidine compounds
WO2013113776A1 (en) 2012-02-03 2013-08-08 Basf Se Fungicidal pyrimidine compounds
WO2013113716A1 (en) 2012-02-03 2013-08-08 Basf Se Fungicidal pyrimidine compounds
WO2013113715A1 (en) 2012-02-03 2013-08-08 Basf Se Fungicidal pyrimidine compounds
JP2015533131A (ja) 2012-10-09 2015-11-19 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 咳を治療するためのベータ2−アドレナリン受容体作動薬
US10059678B2 (en) 2014-09-09 2018-08-28 G. Pratap REDDY Process for preparing olodaterol and intermediates thereof
US20200069679A1 (en) 2016-12-12 2020-03-05 Boehringer Ingelheim International Gmbh Nintedanib for use in methods for the treatment of interstitial lung diseases by coadministration with oladaterol
PL3558954T3 (pl) 2016-12-20 2022-01-31 Inke, S.A. Ulepszony sposób wytwarzania chlorowodorku r-6-hydroxy-8-[1-hydroksy-2-[2-(4-metoksyfenylo)-1,1-dimetyloetyloaminoetylo]-2h-1,4-benzoksazyno-3(4h)-onu
CN108997248B (zh) * 2018-08-06 2023-08-01 上海方予健康医药科技有限公司 盐酸奥达特罗晶型b及其制备方法
CN109096218B (zh) * 2018-08-06 2020-10-27 上海方予健康医药科技有限公司 盐酸奥达特罗晶型a及其制备方法
CN112592323B (zh) * 2020-06-11 2022-07-01 上海谷森医药有限公司 奥达特罗及其盐的制备方法

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US20070088160A1 (en) 2007-04-19
DK1917253T3 (da) 2015-03-30
MX2008001976A (es) 2008-03-25
WO2007020227A1 (de) 2007-02-22
CA2619402C (en) 2015-02-03
US20110124859A1 (en) 2011-05-26
CA2619402A1 (en) 2007-02-22
NZ566577A (en) 2011-04-29
JP2009504708A (ja) 2009-02-05
AU2006281449B2 (en) 2013-01-31
RU2412176C2 (ru) 2011-02-20
JP5270343B2 (ja) 2013-08-21
UY29742A1 (es) 2007-03-30
RU2008109650A (ru) 2009-09-27
PE20070418A1 (es) 2007-05-28
ES2530991T3 (es) 2015-03-09
KR101360803B1 (ko) 2014-02-11
ZA200710049B (en) 2008-11-26
EP1917253A1 (de) 2008-05-07
KR20080049049A (ko) 2008-06-03
CN101208316B (zh) 2012-05-09
US8420809B2 (en) 2013-04-16
AU2006281449A1 (en) 2007-02-22
CN101208316A (zh) 2008-06-25
EP1917253B1 (de) 2015-01-07
BRPI0614410A2 (pt) 2011-03-29
AR056456A1 (es) 2007-10-10
TW200800925A (en) 2008-01-01
TWI412523B (zh) 2013-10-21
IL189460A (en) 2013-08-29

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