PL1917253T3 - Sposób wytwarzania betamimetyków - Google Patents
Sposób wytwarzania betamimetykówInfo
- Publication number
- PL1917253T3 PL1917253T3 PL06778214T PL06778214T PL1917253T3 PL 1917253 T3 PL1917253 T3 PL 1917253T3 PL 06778214 T PL06778214 T PL 06778214T PL 06778214 T PL06778214 T PL 06778214T PL 1917253 T3 PL1917253 T3 PL 1917253T3
- Authority
- PL
- Poland
- Prior art keywords
- betamimetics
- producing
- producing betamimetics
- Prior art date
Links
- 239000000808 adrenergic beta-agonist Substances 0.000 title 1
- 230000003454 betamimetic effect Effects 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
- C07D265/34—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings
- C07D265/36—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings condensed with one six-membered ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C201/00—Preparation of esters of nitric or nitrous acid or of compounds containing nitro or nitroso groups bound to a carbon skeleton
- C07C201/06—Preparation of nitro compounds
- C07C201/08—Preparation of nitro compounds by substitution of hydrogen atoms by nitro groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C221/00—Preparation of compounds containing amino groups and doubly-bound oxygen atoms bound to the same carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/12—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by halogen atoms or by nitro or nitroso groups
- C07C233/13—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by halogen atoms or by nitro or nitroso groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/16—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
- C07C233/17—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
- C07C233/18—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom having the carbon atom of the carboxamide group bound to a hydrogen atom or to a carbon atom of an acyclic saturated carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
- C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
- C07C45/70—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form
- C07C45/71—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form being hydroxy groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
- C07C49/84—Ketones containing a keto group bound to a six-membered aromatic ring containing ether groups, groups, groups, or groups
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Pulmonology (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP05107470 | 2005-08-15 | ||
EP06778214.4A EP1917253B1 (de) | 2005-08-15 | 2006-08-10 | Verfahren zur herstellung von betamimetika |
PCT/EP2006/065217 WO2007020227A1 (de) | 2005-08-15 | 2006-08-10 | Verfahren zur herstellung von betamimetika |
Publications (1)
Publication Number | Publication Date |
---|---|
PL1917253T3 true PL1917253T3 (pl) | 2015-06-30 |
Family
ID=37198936
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PL06778214T PL1917253T3 (pl) | 2005-08-15 | 2006-08-10 | Sposób wytwarzania betamimetyków |
Country Status (21)
Country | Link |
---|---|
US (2) | US20070088160A1 (pl) |
EP (1) | EP1917253B1 (pl) |
JP (1) | JP5270343B2 (pl) |
KR (1) | KR101360803B1 (pl) |
CN (1) | CN101208316B (pl) |
AR (1) | AR056456A1 (pl) |
AU (1) | AU2006281449B2 (pl) |
BR (1) | BRPI0614410A2 (pl) |
CA (1) | CA2619402C (pl) |
DK (1) | DK1917253T3 (pl) |
ES (1) | ES2530991T3 (pl) |
IL (1) | IL189460A (pl) |
MX (1) | MX2008001976A (pl) |
NZ (1) | NZ566577A (pl) |
PE (1) | PE20070418A1 (pl) |
PL (1) | PL1917253T3 (pl) |
RU (1) | RU2412176C2 (pl) |
TW (1) | TWI412523B (pl) |
UY (1) | UY29742A1 (pl) |
WO (1) | WO2007020227A1 (pl) |
ZA (1) | ZA200710049B (pl) |
Families Citing this family (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7056916B2 (en) * | 2002-11-15 | 2006-06-06 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Medicaments for the treatment of chronic obstructive pulmonary disease |
US20050272726A1 (en) * | 2004-04-22 | 2005-12-08 | Boehringer Ingelheim International Gmbh | Novel medicaments for the treatment of respiratory diseases |
US7220742B2 (en) * | 2004-05-14 | 2007-05-22 | Boehringer Ingelheim International Gmbh | Enantiomerically pure beta agonists, process for the manufacture thereof and use thereof as medicaments |
US20050256115A1 (en) * | 2004-05-14 | 2005-11-17 | Boehringer Ingelheim International Gmbh | Aerosol formulation for the inhalation of beta-agonists |
US20050255050A1 (en) * | 2004-05-14 | 2005-11-17 | Boehringer Ingelheim International Gmbh | Powder formulations for inhalation, comprising enantiomerically pure beta agonists |
PL1917253T3 (pl) | 2005-08-15 | 2015-06-30 | Boehringer Ingelheim Int | Sposób wytwarzania betamimetyków |
PL2125759T3 (pl) * | 2007-01-25 | 2011-12-30 | Boehringer Ingelheim Int | Sposób wytwarzania związków betamimetycznych |
CN101704756B (zh) * | 2009-11-20 | 2017-12-05 | 大连九信精细化工有限公司 | 1—(4—氟苯基)—2—甲基—2—丙胺的合成方法 |
WO2013113778A1 (en) | 2012-02-03 | 2013-08-08 | Basf Se | Fungicidal pyrimidine compounds |
EA201491472A1 (ru) | 2012-02-03 | 2015-01-30 | Басф Се | Фунгицидные соединения пиримидина |
WO2013113788A1 (en) | 2012-02-03 | 2013-08-08 | Basf Se | Fungicidal pyrimidine compounds |
WO2013113720A1 (en) | 2012-02-03 | 2013-08-08 | Basf Se | Fungicidal pyrimidine compounds |
WO2013113773A1 (en) | 2012-02-03 | 2013-08-08 | Basf Se | Fungicidal pyrimidine compounds |
WO2013113776A1 (en) | 2012-02-03 | 2013-08-08 | Basf Se | Fungicidal pyrimidine compounds |
WO2013113716A1 (en) | 2012-02-03 | 2013-08-08 | Basf Se | Fungicidal pyrimidine compounds |
WO2013113715A1 (en) | 2012-02-03 | 2013-08-08 | Basf Se | Fungicidal pyrimidine compounds |
JP2015533131A (ja) | 2012-10-09 | 2015-11-19 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | 咳を治療するためのベータ2−アドレナリン受容体作動薬 |
US10059678B2 (en) | 2014-09-09 | 2018-08-28 | G. Pratap REDDY | Process for preparing olodaterol and intermediates thereof |
US20200069679A1 (en) | 2016-12-12 | 2020-03-05 | Boehringer Ingelheim International Gmbh | Nintedanib for use in methods for the treatment of interstitial lung diseases by coadministration with oladaterol |
PL3558954T3 (pl) | 2016-12-20 | 2022-01-31 | Inke, S.A. | Ulepszony sposób wytwarzania chlorowodorku r-6-hydroxy-8-[1-hydroksy-2-[2-(4-metoksyfenylo)-1,1-dimetyloetyloaminoetylo]-2h-1,4-benzoksazyno-3(4h)-onu |
CN108997248B (zh) * | 2018-08-06 | 2023-08-01 | 上海方予健康医药科技有限公司 | 盐酸奥达特罗晶型b及其制备方法 |
CN109096218B (zh) * | 2018-08-06 | 2020-10-27 | 上海方予健康医药科技有限公司 | 盐酸奥达特罗晶型a及其制备方法 |
CN112592323B (zh) * | 2020-06-11 | 2022-07-01 | 上海谷森医药有限公司 | 奥达特罗及其盐的制备方法 |
Family Cites Families (115)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE1144713B (de) * | 1960-10-14 | 1963-03-07 | Troponwerke Dinklage & Co | Verfahren zur Herstellung von N-substituierten Carbonsaeureamiden |
DE2609645A1 (de) * | 1976-03-09 | 1977-09-15 | Boehringer Sohn Ingelheim | Aminoalkylheterocyclen |
US4252951A (en) * | 1979-10-09 | 1981-02-24 | Eli Lilly And Company | Isolation of syn-7-(2-amino-4-thiazolyl)-(methoxyimino)acetamido-3-acetoxymethyl-3-cephem-4-carboxylic acid |
US4656168A (en) * | 1980-12-23 | 1987-04-07 | Merck & Co., Inc. | (3-aralkylamino-2-or-propoxy)heterocyclic compounds in method of effecting bronchodilation |
FR2510104A1 (fr) | 1981-07-27 | 1983-01-28 | Rhone Poulenc Agrochimie | Composes herbicides derives d'acides phenoxybenzoiques |
JPS5824431A (ja) | 1981-08-06 | 1983-02-14 | Sumitomo Rubber Ind Ltd | エラストマ−物品の予熱方法 |
DE3134590A1 (de) * | 1981-09-01 | 1983-03-10 | Boehringer Ingelheim KG, 6507 Ingelheim | Neue benzo-heterocyclen |
US4460581A (en) * | 1982-10-12 | 1984-07-17 | Boehringer Ingelheim Kg | (1-Hydroxy-2-amino-alkyl)-substituted benzoxazinones and benzoxazolinones |
DE3327400A1 (de) * | 1983-07-29 | 1985-02-07 | Alfred Teves Gmbh, 6000 Frankfurt | Vorrichtung zur erfassung der umfangsgeschwindigkeit einer in drehung versetzbaren zahnscheibe |
US4570630A (en) * | 1983-08-03 | 1986-02-18 | Miles Laboratories, Inc. | Medicament inhalation device |
CA1272917A (en) | 1985-07-30 | 1990-08-21 | Paul Kenneth Rand | Devices for administering medicaments to patients |
SE453566B (sv) | 1986-03-07 | 1988-02-15 | Draco Ab | Anordning vid pulverinhalatorer |
DE3743265A1 (de) | 1987-12-19 | 1989-06-29 | Boehringer Ingelheim Kg | Neue ammoniumverbindungen, ihre herstellung und verwendung |
US5223614A (en) * | 1987-12-19 | 1993-06-29 | Boehringer Ingelheim Gmbh | New quaternary ammonium compounds, their preparation and use |
SG45171A1 (en) | 1990-03-21 | 1998-01-16 | Boehringer Ingelheim Int | Atomising devices and methods |
US5502078A (en) * | 1991-05-28 | 1996-03-26 | Zeneca Limited | Chemical compounds |
IL107120A (en) | 1992-09-29 | 1997-09-30 | Boehringer Ingelheim Int | Atomising nozzle and filter and spray generating device |
US6007676A (en) * | 1992-09-29 | 1999-12-28 | Boehringer Ingelheim International Gmbh | Atomizing nozzle and filter and spray generating device |
KR100312357B1 (ko) * | 1992-12-09 | 2002-04-24 | 데이비드 이. 프랭크하우저 | 안정화된약제의에어로졸용액제제 |
DE4318455A1 (de) * | 1993-06-03 | 1994-12-08 | Boehringer Ingelheim Kg | Kapselhalterung |
GB9322014D0 (en) * | 1993-10-26 | 1993-12-15 | Co Ordinated Drug Dev | Improvements in and relating to carrier particles for use in dry powder inhalers |
GB9405019D0 (en) * | 1994-03-15 | 1994-04-27 | Smithkline Beecham Plc | Novel compounds |
JP3875993B2 (ja) | 1995-06-27 | 2007-01-31 | ベーリンガー インゲルハイム コマンディトゲゼルシャフト | 噴射剤を含まないエアゾールを製造するための新規で安定な医薬調製物 |
DE19536902A1 (de) | 1995-10-04 | 1997-04-10 | Boehringer Ingelheim Int | Vorrichtung zur Hochdruckerzeugung in einem Fluid in Miniaturausführung |
DE19536903C2 (de) * | 1995-10-04 | 1998-09-10 | Boehringer Ingelheim Int | Vorrichtung zum Haltern eines fluidischen Bauteils |
DE19545226C1 (de) | 1995-12-05 | 1997-06-19 | Boehringer Ingelheim Int | Sperrspannwerk für einen federbetätigten Abtrieb |
US5753417A (en) * | 1996-06-10 | 1998-05-19 | Sharp Microelectronics Technology, Inc. | Multiple exposure masking system for forming multi-level resist profiles |
DE59600683D1 (de) * | 1996-11-27 | 1998-11-19 | Pfleger R Chem Fab | Verwendung von Trospiumchlorid zur Herstellung eines Arzneimittels zur Behandlung von Blasenkrankheiten |
DE19653969A1 (de) | 1996-12-20 | 1998-06-25 | Boehringer Ingelheim Kg | Neue wässrige Arzneimittelzubereitung zur Erzeugung treibgasfreier Aerosole |
DE19724397A1 (de) * | 1997-06-10 | 1999-01-14 | Bayer Ag | UV-Stabilisatoren für Siloxan-Systeme |
DE19742439C1 (de) | 1997-09-26 | 1998-10-22 | Boehringer Ingelheim Int | Mikrostrukturiertes Filter |
GB0003935D0 (en) | 2000-02-08 | 2000-04-12 | King S College London | Formulation for dry powder inhaler |
GB0009592D0 (en) * | 2000-04-18 | 2000-06-07 | Glaxo Group Ltd | Respiratory combinations |
CN1426401A (zh) * | 2000-04-27 | 2003-06-25 | 贝林格尔英格海姆法玛公司 | 新的长效倍他米美类药物(betamimetics)其制备方法,及其作为药物组合物的用途 |
US6960597B2 (en) * | 2000-06-30 | 2005-11-01 | Orth-Mcneil Pharmaceutical, Inc. | Aza-bridged-bicyclic amino acid derivatives as α4 integrin antagonists |
EP1326862B1 (de) | 2000-10-12 | 2004-09-15 | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG | Kristallines monohydrat von tiotropiumbromid, verfahren zu dessen herstellung und dessen verwendung zur herstellung eines arzneimittels |
US6852728B2 (en) * | 2000-10-14 | 2005-02-08 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Anticholinergics, processes for preparing them, and pharmaceutical compositions containing them |
DE10050994A1 (de) | 2000-10-14 | 2002-04-18 | Boehringer Ingelheim Pharma | Neue als Arneimittel einsetzbare Anticholinergika sowie Verfahren zu deren Herstellung |
US6706726B2 (en) * | 2000-10-14 | 2004-03-16 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Anticholinergics which may be used as medicaments as well as processes for preparing them |
US20020193393A1 (en) * | 2001-03-07 | 2002-12-19 | Michel Pairet | Pharmaceutical compositions based on anticholinergics and PDE-IV inhibitors |
US20020189610A1 (en) * | 2001-02-01 | 2002-12-19 | Karl-Heinz Bozung | Pharmaceutical compositions containing an ipratropium salt and a betamimetic |
GB0107106D0 (en) | 2001-03-21 | 2001-05-09 | Boehringer Ingelheim Pharma | Powder inhaler formulations |
IL159238A0 (en) | 2001-06-22 | 2004-06-01 | Boehringer Ingelheim Pharma | Crystalline anticholinergic, method for its production, and use thereof in the production of a drug |
DE10130371A1 (de) | 2001-06-23 | 2003-01-02 | Boehringer Ingelheim Pharma | Neue Arzneimittelkompositionen auf der Basis von Anticholinergika, Corticosteroiden und Betamimetika |
US20030018019A1 (en) * | 2001-06-23 | 2003-01-23 | Boehringer Ingelheim Pharma Kg | Pharmaceutical compositions based on anticholinergics, corticosteroids and betamimetics |
GB2377934B (en) | 2001-07-25 | 2005-01-12 | Portela & Ca Sa | Method for the nitration of phenolic compounds |
DE10141377A1 (de) * | 2001-08-23 | 2003-03-13 | Boehringer Ingelheim Pharma | Aufstreuverfahren zur Herstellung von Pulverformulierungen |
DE10200943A1 (de) * | 2002-01-12 | 2003-07-24 | Boehringer Ingelheim Pharma | Verfahren zur Herstellung von Scopinestern |
US6696462B2 (en) * | 2002-01-31 | 2004-02-24 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Anticholinergics, processes for the preparation thereof, and pharmaceutical compositions |
DE10203753A1 (de) | 2002-01-31 | 2003-08-14 | Boehringer Ingelheim Pharma | Neue Xanthencarbonsäureester, Verfahren zu deren Herstellung sowie deren Verwendung als Arzneimittel |
DE10212264A1 (de) | 2002-03-20 | 2003-10-02 | Boehringer Ingelheim Pharma | Kristallines Mikronisat, Verfahren zu dessen Herstellung und dessen Verwendung zur Herstellung eines Arzneimittels |
UA80123C2 (en) | 2002-04-09 | 2007-08-27 | Boehringer Ingelheim Pharma | Inhalation kit comprising inhalable powder of tiotropium |
DE10216427A1 (de) * | 2002-04-12 | 2003-10-23 | Boehringer Ingelheim Pharma | Arzneimittelkompositionen enthaltend heterocyclische Verbindungen und ein neues Anticholinergikum |
US7417051B2 (en) * | 2002-04-12 | 2008-08-26 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Medicaments comprising betamimetics and a novel anticholinergic |
US7084153B2 (en) * | 2002-04-12 | 2006-08-01 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Medicaments comprising steroids and a novel anticholinergic |
ES2203327B1 (es) | 2002-06-21 | 2005-06-16 | Almirall Prodesfarma, S.A. | Nuevos carbamatos de quinuclidina y composiciones farmaceuticas que los contienen. |
US20040048887A1 (en) * | 2002-07-09 | 2004-03-11 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Pharmaceutical compositions based on anticholinergics and EGFR kinase inhibitors |
US20040048886A1 (en) * | 2002-07-09 | 2004-03-11 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Pharmaceutical compositions based on new anticholinergics and NK1 receptor antagonists |
US20040058950A1 (en) * | 2002-07-09 | 2004-03-25 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Pharmaceutical compositions based on anticholinergics and PDE-IV inhibitors |
DE10230751A1 (de) | 2002-07-09 | 2004-01-22 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Neue Arzneimittelkompositionen auf der Basis neuer Anticholinergika und EGFR-Kinase-Hemmern |
US20040044020A1 (en) * | 2002-07-09 | 2004-03-04 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Pharmaceutical compositions based on novel anticholinergics and p38 kinase inhibitors |
US20040166065A1 (en) * | 2002-08-14 | 2004-08-26 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Aerosol formulation for inhalation comprising an anticholinergic |
DE10237739A1 (de) | 2002-08-17 | 2004-02-26 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Inhalative Arzneimittel enthaltend ein neues Anticholinergikum in Kombination mit Corticosteroiden und Betamimetika |
US7244742B2 (en) * | 2002-08-17 | 2007-07-17 | Boehringer Ingelheim Pharma Gmbh & Co Kg | Pharmaceutical compositions for inhalation containing an anticholinergic, corticosteroid and betamimetic |
DE10246374A1 (de) | 2002-10-04 | 2004-04-15 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Neue Betamimetika mit verlängerter Wirkungsdauer, Verfahren zu deren Herstellung und deren Verwendung als Arzneimittel |
US6951888B2 (en) * | 2002-10-04 | 2005-10-04 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Betamimetics with a prolonged duration of activity, processes for preparing them, and their use as pharmaceutical compositions |
US7056916B2 (en) * | 2002-11-15 | 2006-06-06 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Medicaments for the treatment of chronic obstructive pulmonary disease |
DE10253220A1 (de) * | 2002-11-15 | 2004-05-27 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Neue Dihydroxy-Methyl-Phenyl-Derivate, Verfahren zu deren Herstellung und deren Verwendung als Arzneimittel |
DE10253282A1 (de) | 2002-11-15 | 2004-05-27 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Neue Arzneimittel zur Behandlung von chronisch obstruktiver Lungenerkrankung |
US7250426B2 (en) * | 2002-11-29 | 2007-07-31 | Boehringer Ingelheim Pharma Gmbh & Co Kg | Tiotropium-containing pharmaceutical combination for inhalation |
BR0316386A (pt) * | 2002-12-06 | 2005-09-27 | Warner Lambert Co | Benzoxazin-3-onas e seus derivados como inibidores de p13k |
AU2004226824B2 (en) * | 2003-04-04 | 2008-05-01 | Novartis Ag | Quinoline-2-one-derivatives for the treatment of airways diseases |
US7332175B2 (en) * | 2003-05-27 | 2008-02-19 | Boehringer Ingelheim International Gmbh | Long-acting drug combinations for the treatment of respiratory complaints |
US7273603B2 (en) * | 2003-07-11 | 2007-09-25 | Boehringer Ingelheim International Gmbh | HFC solution formulations containing an anticholinergic |
US20050026948A1 (en) * | 2003-07-29 | 2005-02-03 | Boehringer Ingelheim International Gmbh | Medicaments for inhalation comprising an anticholinergic and a betamimetic |
ES2284025T3 (es) | 2003-07-29 | 2007-11-01 | Boehringer Ingelheim International Gmbh | Medicamentos para inhalar que comprenden betamimeticos y un anticolinergico. |
US20050025718A1 (en) * | 2003-07-31 | 2005-02-03 | Boehringer Ingelheim International Gmbh | Medicaments for inhalation comprising an anticholinergic and a betamimetic |
US6905304B2 (en) * | 2003-09-23 | 2005-06-14 | Taiwan Trigem Information Co., Ltd. | Heat dissipation fan |
DE10345065A1 (de) * | 2003-09-26 | 2005-04-14 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Aerosolformulierung für die Inhalation enthaltend ein Anticholinergikum |
US20050154006A1 (en) * | 2004-01-09 | 2005-07-14 | Boehringer Ingelheim International Gmbh | Pharmaceutical compositions based on a scopineester and nicotinamide derivatives |
DE102004003428A1 (de) * | 2004-01-23 | 2005-08-11 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Neue langwirksame Beta-2-Agonisten, und deren Verwendung als Arzneimittel |
US20050186175A1 (en) * | 2004-02-20 | 2005-08-25 | Boehringer Ingelheim International Gmbh | Pharmaceutical compositions based on benzilic acid esters and soluble TNF receptor fusion proteins |
DE102004019540A1 (de) | 2004-04-22 | 2005-11-10 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Neue Arzneimittelkombinationen zur Behandlung von Atemwegserkrankungen |
US7244728B2 (en) * | 2004-03-17 | 2007-07-17 | Boehringer Ingelheim International Gmbh | Long acting betamimetics for the treatment of respiratory diseases |
EP1577306A1 (de) | 2004-03-17 | 2005-09-21 | Boehringer Ingelheim Pharma GmbH & Co.KG | Neue Benzoxazinonderivate als langwirksame Betamimetika zur Behandlung von Atemwegserkrankungen |
US20050239778A1 (en) * | 2004-04-22 | 2005-10-27 | Boehringer Ingelheim International Gmbh | Novel medicament combinations for the treatment of respiratory diseases |
EP1781298B1 (de) | 2004-04-22 | 2012-01-04 | Boehringer Ingelheim International GmbH | Arzneinmittelkombinationen enthaltend benzoxazine zur behandlung von atemwegserkrankungen |
US20050272726A1 (en) | 2004-04-22 | 2005-12-08 | Boehringer Ingelheim International Gmbh | Novel medicaments for the treatment of respiratory diseases |
DE102004019539A1 (de) | 2004-04-22 | 2005-11-10 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Neue Arzneimittel zur Behandlung von Atemwegserkrankungen |
US7307076B2 (en) * | 2004-05-13 | 2007-12-11 | Boehringer Ingelheim International Gmbh | Beta agonists for the treatment of respiratory diseases |
DE102004024452A1 (de) | 2004-05-14 | 2005-12-08 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Aerosolformulierung für die Inhalation von Betaagonisten |
DE102004024451A1 (de) * | 2004-05-14 | 2005-12-22 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Pulverformulierungen für die Inhalation, die Enantiomerenreine Betaagonisten enthalten |
US7220742B2 (en) * | 2004-05-14 | 2007-05-22 | Boehringer Ingelheim International Gmbh | Enantiomerically pure beta agonists, process for the manufacture thereof and use thereof as medicaments |
US20050256115A1 (en) * | 2004-05-14 | 2005-11-17 | Boehringer Ingelheim International Gmbh | Aerosol formulation for the inhalation of beta-agonists |
US20050255050A1 (en) | 2004-05-14 | 2005-11-17 | Boehringer Ingelheim International Gmbh | Powder formulations for inhalation, comprising enantiomerically pure beta agonists |
US7745621B2 (en) * | 2004-05-14 | 2010-06-29 | Boehringer Ingelheim International Gmbh | Long acting bronchodilators for the treatment of respiratory diseases |
DE102004024454A1 (de) * | 2004-05-14 | 2005-12-08 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Neue Enantiomerenreine Betaagonisten, Verfahren zu deren Herstellung und deren Verwendung als Arzneimittel |
KR100598105B1 (ko) * | 2004-06-17 | 2006-07-07 | 삼성전자주식회사 | 반도체 패턴 형성 방법 |
EP1778626A1 (en) * | 2004-08-16 | 2007-05-02 | Theravance, Inc. | Compounds having beta2 adrenergic receptor agonist and muscarinic receptor antagonist activity |
DE102004045648A1 (de) * | 2004-09-21 | 2006-03-23 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Neue Betamimetika zur Behandlung von Atemwegserkrankungen |
DE102005007654A1 (de) * | 2005-02-19 | 2006-08-24 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Neue langwirksame Betamimetika zur Behandlung von Atemwegserkrankungen |
PL1917253T3 (pl) * | 2005-08-15 | 2015-06-30 | Boehringer Ingelheim Int | Sposób wytwarzania betamimetyków |
US20070086957A1 (en) | 2005-10-10 | 2007-04-19 | Thierry Bouyssou | Combination of medicaments for the treatment of respiratory diseases |
TWI389692B (zh) | 2005-10-10 | 2013-03-21 | Boehringer Ingelheim Int | 用以吸入β-共效劑的氣溶膠調配物 |
ES2380952T3 (es) | 2005-10-11 | 2012-05-21 | Bayer Consumer Care Ag | Mezcla de sales de hierro y cobre que enmascaran el sabor metálico. |
AU2006311060A1 (en) * | 2005-11-09 | 2007-05-18 | Boehringer Ingelheim International Gmbh | Aerosolformulation for inhalation |
US7579137B2 (en) * | 2005-12-24 | 2009-08-25 | International Business Machines Corporation | Method for fabricating dual damascene structures |
TW200815054A (en) | 2006-06-19 | 2008-04-01 | Otsuka Pharma Co Ltd | Methods of using a thiazole derivative |
UY30543A1 (es) * | 2006-08-18 | 2008-03-31 | Boehringer Ingelheim Int | Formulacion de aerosol para la inhalacion de beta- agonistas |
UY30542A1 (es) | 2006-08-18 | 2008-03-31 | Boehringer Ingelheim Int | Formulacion de aerosol para la inhalacion de agonistas beta |
TWI482772B (zh) | 2006-08-21 | 2015-05-01 | Astrazeneca Ab | 適合口服且包含三唑并[4,5-d]嘧啶衍生物之組合物 |
PL2125759T3 (pl) | 2007-01-25 | 2011-12-30 | Boehringer Ingelheim Int | Sposób wytwarzania związków betamimetycznych |
BRPI0819224A2 (pt) | 2007-11-05 | 2015-05-05 | Boehringer Ingelheim Int | Hidrato cristalino de beta-mimético e o uso como medicamento do mesmo |
CA2738616A1 (en) | 2008-11-21 | 2010-05-27 | Boehringer Ingelheim International Gmbh | Aerosol formulation for the inhalation of beta agonists |
CA2738617A1 (en) | 2008-11-21 | 2011-05-27 | Boehringer Ingelheim International Gmbh | Aerosol formulation for the inhalation of beta agonists |
-
2006
- 2006-08-10 PL PL06778214T patent/PL1917253T3/pl unknown
- 2006-08-10 CN CN2006800232661A patent/CN101208316B/zh active Active
- 2006-08-10 DK DK06778214T patent/DK1917253T3/da active
- 2006-08-10 ES ES06778214T patent/ES2530991T3/es active Active
- 2006-08-10 RU RU2008109650/04A patent/RU2412176C2/ru active
- 2006-08-10 AU AU2006281449A patent/AU2006281449B2/en active Active
- 2006-08-10 BR BRPI0614410-1A patent/BRPI0614410A2/pt not_active Application Discontinuation
- 2006-08-10 NZ NZ566577A patent/NZ566577A/en unknown
- 2006-08-10 JP JP2008526484A patent/JP5270343B2/ja active Active
- 2006-08-10 KR KR1020087006338A patent/KR101360803B1/ko active Active
- 2006-08-10 MX MX2008001976A patent/MX2008001976A/es active IP Right Grant
- 2006-08-10 CA CA2619402A patent/CA2619402C/en active Active
- 2006-08-10 WO PCT/EP2006/065217 patent/WO2007020227A1/de active Application Filing
- 2006-08-10 EP EP06778214.4A patent/EP1917253B1/de active Active
- 2006-08-10 US US11/463,703 patent/US20070088160A1/en not_active Abandoned
- 2006-08-11 PE PE2006000982A patent/PE20070418A1/es not_active Application Discontinuation
- 2006-08-11 AR ARP060103519A patent/AR056456A1/es active IP Right Grant
- 2006-08-11 UY UY29742A patent/UY29742A1/es not_active Application Discontinuation
- 2006-08-14 TW TW095129785A patent/TWI412523B/zh active
-
2007
- 2007-11-21 ZA ZA200710049A patent/ZA200710049B/xx unknown
-
2008
- 2008-02-12 IL IL189460A patent/IL189460A/en not_active IP Right Cessation
-
2011
- 2011-02-07 US US13/021,946 patent/US8420809B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
US20070088160A1 (en) | 2007-04-19 |
DK1917253T3 (da) | 2015-03-30 |
MX2008001976A (es) | 2008-03-25 |
WO2007020227A1 (de) | 2007-02-22 |
CA2619402C (en) | 2015-02-03 |
US20110124859A1 (en) | 2011-05-26 |
CA2619402A1 (en) | 2007-02-22 |
NZ566577A (en) | 2011-04-29 |
JP2009504708A (ja) | 2009-02-05 |
AU2006281449B2 (en) | 2013-01-31 |
RU2412176C2 (ru) | 2011-02-20 |
JP5270343B2 (ja) | 2013-08-21 |
UY29742A1 (es) | 2007-03-30 |
RU2008109650A (ru) | 2009-09-27 |
PE20070418A1 (es) | 2007-05-28 |
ES2530991T3 (es) | 2015-03-09 |
KR101360803B1 (ko) | 2014-02-11 |
ZA200710049B (en) | 2008-11-26 |
EP1917253A1 (de) | 2008-05-07 |
KR20080049049A (ko) | 2008-06-03 |
CN101208316B (zh) | 2012-05-09 |
US8420809B2 (en) | 2013-04-16 |
AU2006281449A1 (en) | 2007-02-22 |
CN101208316A (zh) | 2008-06-25 |
EP1917253B1 (de) | 2015-01-07 |
BRPI0614410A2 (pt) | 2011-03-29 |
AR056456A1 (es) | 2007-10-10 |
TW200800925A (en) | 2008-01-01 |
TWI412523B (zh) | 2013-10-21 |
IL189460A (en) | 2013-08-29 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ZA200710049B (en) | Method for producing betamimetics | |
PL2546205T3 (pl) | Sposób wytwarzania fiolek | |
PL1869471T3 (pl) | Sposób wytwarzania cirkowirusa świń | |
EP1864785A4 (en) | SETEROLITHOGRAPHIEVERFAHREN | |
HK1116471A1 (en) | Continuous method for making chlorhydrines | |
GB0503836D0 (en) | Method | |
IL199985A0 (en) | Method for producing betamimetics | |
IL185627A0 (en) | Alkyl-anilide producing method | |
PL1896599T3 (pl) | Sposób wytwarzania L-treoniny | |
ZA200708208B (en) | Process for producing cyclopropylphenol derivative | |
GB0504096D0 (en) | Method | |
GB0504184D0 (en) | Method | |
IL188777A0 (en) | Method for producing nebivolol | |
EP1939301A4 (en) | PROCESS FOR PRODUCING A USEFUL SUBSTANCE | |
ZA200708847B (en) | Method for producing sulfamate-carboxylate derivative | |
PL1865784T3 (pl) | Sposób wytwarzania pojedynczych porcji | |
GB0502046D0 (en) | Method | |
EP1860069A4 (en) | PROCESS FOR PREPARING A COMPOSITION | |
ZA200709013B (en) | Method for producing 2-isopropenyl-5-methyl-4-hexen-1-yl 3-methyl-2-butenoate | |
EP1930435A4 (en) | PROCESS FOR PRODUCING A USEFUL SUBSTANCE | |
EP1836310A4 (en) | PROCESS FOR PREPARING PROBIOTICALLY OBTAINED COMPOUNDS | |
EP1976858A4 (en) | PROCESS FOR THE PREPARATION OF 4-DEMETHYLDAUNORUBICIN | |
EP1860943A4 (en) | NOVEL PROCEDURE | |
EP1903047A4 (en) | PROCESS FOR THE PREPARATION OF TRIHYDROCARBYLBORAN | |
GB0504182D0 (en) | Method |