PL1917018T3 - Inulin sulphate for the treatment of osteoarthritis - Google Patents
Inulin sulphate for the treatment of osteoarthritisInfo
- Publication number
- PL1917018T3 PL1917018T3 PL05707336T PL05707336T PL1917018T3 PL 1917018 T3 PL1917018 T3 PL 1917018T3 PL 05707336 T PL05707336 T PL 05707336T PL 05707336 T PL05707336 T PL 05707336T PL 1917018 T3 PL1917018 T3 PL 1917018T3
- Authority
- PL
- Poland
- Prior art keywords
- sulphate
- inulin
- treatment
- sulphated
- polysaccharide
- Prior art date
Links
- QAOWNCQODCNURD-UHFFFAOYSA-L Sulfate Chemical compound [O-]S([O-])(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-L 0.000 title abstract 9
- 229910021653 sulphate ion Inorganic materials 0.000 title abstract 9
- 229920001202 Inulin Polymers 0.000 title abstract 5
- JYJIGFIDKWBXDU-MNNPPOADSA-N inulin Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)OC[C@]1(OC[C@]2(OC[C@]3(OC[C@]4(OC[C@]5(OC[C@]6(OC[C@]7(OC[C@]8(OC[C@]9(OC[C@]%10(OC[C@]%11(OC[C@]%12(OC[C@]%13(OC[C@]%14(OC[C@]%15(OC[C@]%16(OC[C@]%17(OC[C@]%18(OC[C@]%19(OC[C@]%20(OC[C@]%21(OC[C@]%22(OC[C@]%23(OC[C@]%24(OC[C@]%25(OC[C@]%26(OC[C@]%27(OC[C@]%28(OC[C@]%29(OC[C@]%30(OC[C@]%31(OC[C@]%32(OC[C@]%33(OC[C@]%34(OC[C@]%35(OC[C@]%36(O[C@@H]%37[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O%37)O)[C@H]([C@H](O)[C@@H](CO)O%36)O)[C@H]([C@H](O)[C@@H](CO)O%35)O)[C@H]([C@H](O)[C@@H](CO)O%34)O)[C@H]([C@H](O)[C@@H](CO)O%33)O)[C@H]([C@H](O)[C@@H](CO)O%32)O)[C@H]([C@H](O)[C@@H](CO)O%31)O)[C@H]([C@H](O)[C@@H](CO)O%30)O)[C@H]([C@H](O)[C@@H](CO)O%29)O)[C@H]([C@H](O)[C@@H](CO)O%28)O)[C@H]([C@H](O)[C@@H](CO)O%27)O)[C@H]([C@H](O)[C@@H](CO)O%26)O)[C@H]([C@H](O)[C@@H](CO)O%25)O)[C@H]([C@H](O)[C@@H](CO)O%24)O)[C@H]([C@H](O)[C@@H](CO)O%23)O)[C@H]([C@H](O)[C@@H](CO)O%22)O)[C@H]([C@H](O)[C@@H](CO)O%21)O)[C@H]([C@H](O)[C@@H](CO)O%20)O)[C@H]([C@H](O)[C@@H](CO)O%19)O)[C@H]([C@H](O)[C@@H](CO)O%18)O)[C@H]([C@H](O)[C@@H](CO)O%17)O)[C@H]([C@H](O)[C@@H](CO)O%16)O)[C@H]([C@H](O)[C@@H](CO)O%15)O)[C@H]([C@H](O)[C@@H](CO)O%14)O)[C@H]([C@H](O)[C@@H](CO)O%13)O)[C@H]([C@H](O)[C@@H](CO)O%12)O)[C@H]([C@H](O)[C@@H](CO)O%11)O)[C@H]([C@H](O)[C@@H](CO)O%10)O)[C@H]([C@H](O)[C@@H](CO)O9)O)[C@H]([C@H](O)[C@@H](CO)O8)O)[C@H]([C@H](O)[C@@H](CO)O7)O)[C@H]([C@H](O)[C@@H](CO)O6)O)[C@H]([C@H](O)[C@@H](CO)O5)O)[C@H]([C@H](O)[C@@H](CO)O4)O)[C@H]([C@H](O)[C@@H](CO)O3)O)[C@H]([C@H](O)[C@@H](CO)O2)O)[C@@H](O)[C@H](O)[C@@H](CO)O1 JYJIGFIDKWBXDU-MNNPPOADSA-N 0.000 title abstract 5
- 229940029339 inulin Drugs 0.000 title abstract 5
- 201000008482 osteoarthritis Diseases 0.000 title abstract 3
- 238000011282 treatment Methods 0.000 title abstract 3
- 229920001282 polysaccharide Polymers 0.000 abstract 3
- 239000005017 polysaccharide Substances 0.000 abstract 3
- 150000004804 polysaccharides Chemical class 0.000 abstract 3
- DBTMGCOVALSLOR-DEVYUCJPSA-N (2s,3r,4s,5r,6r)-4-[(2s,3r,4s,5r,6r)-3,5-dihydroxy-6-(hydroxymethyl)-4-[(2s,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxan-2-yl]oxy-6-(hydroxymethyl)oxane-2,3,5-triol Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1O[C@@H]1[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](CO)O[C@H](O)[C@@H]2O)O)O[C@H](CO)[C@H]1O DBTMGCOVALSLOR-DEVYUCJPSA-N 0.000 abstract 2
- 229920002558 Curdlan Polymers 0.000 abstract 2
- 239000001879 Curdlan Substances 0.000 abstract 2
- 229920002148 Gellan gum Polymers 0.000 abstract 2
- 229920001543 Laminarin Polymers 0.000 abstract 2
- 239000005717 Laminarin Substances 0.000 abstract 2
- 241000124008 Mammalia Species 0.000 abstract 2
- 229920001218 Pullulan Polymers 0.000 abstract 2
- 239000004373 Pullulan Substances 0.000 abstract 2
- 239000002253 acid Substances 0.000 abstract 2
- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 abstract 2
- 235000019316 curdlan Nutrition 0.000 abstract 2
- 229940078035 curdlan Drugs 0.000 abstract 2
- 239000003814 drug Substances 0.000 abstract 2
- 229920001277 pectin Polymers 0.000 abstract 2
- 239000001814 pectin Substances 0.000 abstract 2
- 235000010987 pectin Nutrition 0.000 abstract 2
- 238000011321 prophylaxis Methods 0.000 abstract 2
- 235000019423 pullulan Nutrition 0.000 abstract 2
- 239000000783 alginic acid Substances 0.000 abstract 1
- 235000010443 alginic acid Nutrition 0.000 abstract 1
- 229920000615 alginic acid Polymers 0.000 abstract 1
- 229960001126 alginic acid Drugs 0.000 abstract 1
- 150000004781 alginic acids Chemical class 0.000 abstract 1
- 229920001542 oligosaccharide Polymers 0.000 abstract 1
- 150000002482 oligosaccharides Chemical class 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 159000000000 sodium salts Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/737—Sulfated polysaccharides, e.g. chondroitin sulfate, dermatan sulfate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Physical Education & Sports Medicine (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Dermatology (AREA)
- Rheumatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Immunology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
Abstract
The present invention relates to the use of a sulphated polysaccharide in acid form or as a physiologically acceptable salt thereof, selected from the group constituting of inulin sulphate, gellan sulphate, pullulan sulphate, curdlan sulphate, alginiq acid sulphate, laminarin sulphate, and pectin sulphate, for the preparation of a medicament for the treatment or prophylaxis of arthrosis in a mammal. Preferably, the sulphated polysaccharide is inulin sulphate, most preferably inulin polysulphate sodium salt. The present invention also relates to the use of a sulphated oligosaccharide derived from a polysaccharide selected from the group consisting of inulin, gellan, pullulan, curdlan, alginic acid, laminarin, and pectin, for the preparation of a medicament for the treatment or prophylaxis of arthrosis in a mammal.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES200400464A ES2251289B1 (en) | 2004-02-27 | 2004-02-27 | NEW THERAPEUTIC USE OF A GROUP OF SULFATED POLYSACARIDS. |
| EP05707336A EP1917018B1 (en) | 2004-02-27 | 2005-02-11 | Inulin sulphate for the treatment of osteoarthritis |
| PCT/EP2005/001390 WO2005084610A2 (en) | 2004-02-27 | 2005-02-11 | New therapeutic use for a group of sulphated polysaccharides |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL1917018T3 true PL1917018T3 (en) | 2011-03-31 |
Family
ID=34917281
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL05707336T PL1917018T3 (en) | 2004-02-27 | 2005-02-11 | Inulin sulphate for the treatment of osteoarthritis |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US7816329B2 (en) |
| EP (1) | EP1917018B1 (en) |
| JP (1) | JP2007523925A (en) |
| AT (1) | ATE484285T1 (en) |
| AU (1) | AU2005218729A1 (en) |
| CA (1) | CA2555616A1 (en) |
| CY (1) | CY1110910T1 (en) |
| DE (1) | DE602005024186D1 (en) |
| DK (1) | DK1917018T3 (en) |
| ES (2) | ES2251289B1 (en) |
| NZ (1) | NZ549989A (en) |
| PL (1) | PL1917018T3 (en) |
| PT (1) | PT1917018E (en) |
| SI (1) | SI1917018T1 (en) |
| WO (1) | WO2005084610A2 (en) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5002937B2 (en) * | 2005-10-03 | 2012-08-15 | Ｊｎｃ株式会社 | Sulfated polysaccharide and process for producing the same |
| ES2327480B1 (en) * | 2007-06-15 | 2010-08-10 | Bioiberica, S.A. | "DISABLED FOR THE TREATMENT OF TENDONS, LIGAMENTS AND BONES". |
| WO2017109755A1 (en) * | 2015-12-22 | 2017-06-29 | Stemmatters, Biotecnologia E Medicina Regenerativa, S.A | Gellan gum-based hydrogels, methods and uses thereof |
| RU2686075C1 (en) * | 2018-04-11 | 2019-04-24 | Дмитрий Вениаминович Воробьев | Biologically active agent for treating locomotor diseases and a method of treating locomotor diseases |
| WO2021211441A1 (en) * | 2020-04-13 | 2021-10-21 | The Board Of Regents Of The University Of Oklahoma | Modified sugar polymers with low anticoagulant activity and therapeutic activity |
| CN113730646A (en) * | 2021-08-27 | 2021-12-03 | 中国海洋大学 | A kind of high drug-loading degradable alginate sulfate vascular embolization microspheres and preparation method and application thereof |
| CN116179630A (en) * | 2021-11-26 | 2023-05-30 | 中国科学院大连化学物理研究所 | A chemically modified polysaccharide derivative and its preparation and application |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2686779A (en) | 1949-07-18 | 1954-08-17 | Phillips Petroleum Co | Process for producing alkali metal sulfates of cellulose, inulin, dextrin, and starch |
| US4021545A (en) * | 1976-07-12 | 1977-05-03 | American Cyanamid Company | Complement inhibitors |
| FR2543145B1 (en) * | 1983-03-24 | 1986-10-17 | Sanofi Sa | NOVEL XYLAN SULPHATES, THEIR PREPARATION PROCESS AND THEIR ANTI-THROMBOTIC AND HYPOLIPEMIC ACTIVITY |
| DE3854604T2 (en) * | 1987-03-19 | 1996-03-28 | Arthropharm Pty Ltd | ANTI-IGNITION AGENTS AND COMPOSITIONS. |
| US5063210A (en) | 1989-04-20 | 1991-11-05 | Lange Iii Louis G | Use of sulfated polysaccharides to decrease cholesterol and fatty acid absorption |
| WO1992013541A1 (en) * | 1991-01-30 | 1992-08-20 | Hoechst Aktiengesellschaft | Use of substituted polysaccharides for the treatment of degenerative articular ailments |
| JP2844396B2 (en) | 1991-02-07 | 1999-01-06 | ポーラ化成工業株式会社 | Cosmetics |
| AU652022B2 (en) | 1991-02-12 | 1994-08-11 | C.R. Bard Inc. | Injectable medical device |
| DE69319471T2 (en) * | 1992-03-17 | 1999-04-15 | Asahi Medical Co. Ltd., Tokio/Tokyo | Filter medium with limited negative surface charge for the treatment of blood material |
| ATE323424T1 (en) * | 1999-09-22 | 2006-05-15 | Nestle Sa | METHOD FOR INCREASE PET ACTIVITY |
| FR2816213B1 (en) * | 2000-11-03 | 2005-04-22 | Goemar Lab Sa | ANTI-INFLAMMATORY DRUG AND SCARING |
| WO2003006645A2 (en) * | 2001-07-13 | 2003-01-23 | Imclone Systems Incorporated | Method and composition for inhibiting heparanase activity |
| US20030181416A1 (en) * | 2002-01-10 | 2003-09-25 | Comper Wayne D. | Antimicrobial charged polymers that exhibit resistance to lysosomal degradation during kidney filtration and renal passage, compositions and method of use thereof |
| US7988962B2 (en) * | 2003-12-02 | 2011-08-02 | Universiteit Gent | Use of polysulphated alginate in cellular matrices |
-
2004
- 2004-02-27 ES ES200400464A patent/ES2251289B1/en not_active Expired - Fee Related
-
2005
- 2005-02-11 WO PCT/EP2005/001390 patent/WO2005084610A2/en active Application Filing
- 2005-02-11 CA CA002555616A patent/CA2555616A1/en not_active Abandoned
- 2005-02-11 PT PT05707336T patent/PT1917018E/en unknown
- 2005-02-11 EP EP05707336A patent/EP1917018B1/en not_active Expired - Lifetime
- 2005-02-11 US US10/590,311 patent/US7816329B2/en not_active Expired - Fee Related
- 2005-02-11 AU AU2005218729A patent/AU2005218729A1/en not_active Abandoned
- 2005-02-11 NZ NZ549989A patent/NZ549989A/en unknown
- 2005-02-11 JP JP2007500092A patent/JP2007523925A/en active Pending
- 2005-02-11 SI SI200531146T patent/SI1917018T1/en unknown
- 2005-02-11 PL PL05707336T patent/PL1917018T3/en unknown
- 2005-02-11 ES ES05707336T patent/ES2354076T3/en not_active Expired - Lifetime
- 2005-02-11 DE DE602005024186T patent/DE602005024186D1/en not_active Expired - Lifetime
- 2005-02-11 AT AT05707336T patent/ATE484285T1/en active
- 2005-02-11 DK DK05707336.3T patent/DK1917018T3/en active
-
2010
- 2010-11-11 CY CY20101101018T patent/CY1110910T1/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP1917018A2 (en) | 2008-05-07 |
| AU2005218729A1 (en) | 2005-09-15 |
| ATE484285T1 (en) | 2010-10-15 |
| WO2005084610A2 (en) | 2005-09-15 |
| CA2555616A1 (en) | 2005-09-15 |
| JP2007523925A (en) | 2007-08-23 |
| DE602005024186D1 (en) | 2010-11-25 |
| ES2251289A1 (en) | 2006-04-16 |
| ES2354076T3 (en) | 2011-03-09 |
| CY1110910T1 (en) | 2015-06-10 |
| WO2005084610A3 (en) | 2005-12-08 |
| US20080051350A1 (en) | 2008-02-28 |
| EP1917018B1 (en) | 2010-10-13 |
| ES2251289B1 (en) | 2007-07-01 |
| US7816329B2 (en) | 2010-10-19 |
| NZ549989A (en) | 2008-10-31 |
| SI1917018T1 (en) | 2010-12-31 |
| PT1917018E (en) | 2010-12-10 |
| DK1917018T3 (en) | 2011-01-31 |
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