PL1625163T3 - Sposoby wykrywania proBMP przeciwciałem monoklonalnym wiążącym się z aminokwasami 38-43 - Google Patents

Sposoby wykrywania proBMP przeciwciałem monoklonalnym wiążącym się z aminokwasami 38-43

Info

Publication number: PL1625163T3
Authority: PL; Poland
Prior art keywords: amino acids; monoclonal antibody; antibody binding; probnp; native probnp
Prior art date: 2003-05-12

Application number

PL04732278T

Other languages

English (en)

Inventor

Volker Klemt

Anneliese Borgya

Andreas Gallusser

Michael Grol

Klaus Hallermayer

Christoph Seidel

Original Assignee

Hoffmann La Roche

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2003-05-12

Filing date

2004-05-12

Publication date

2012-01-31

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=33427054&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PL1625163(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2004-05-12 Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche

2012-01-31 Publication of PL1625163T3 publication Critical patent/PL1625163T3/pl

Links

238000000034 method Methods 0.000 title abstract 3
150000001413 amino acids Chemical class 0.000 title 1
102100036836 Natriuretic peptides B Human genes 0.000 abstract 5
101710187802 Natriuretic peptides B Proteins 0.000 abstract 5
206010019280 Heart failures Diseases 0.000 abstract 1
238000001514 detection method Methods 0.000 abstract 1
238000003745 diagnosis Methods 0.000 abstract 1
210000004408 hybridoma Anatomy 0.000 abstract 1
238000011895 specific detection Methods 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/26—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against hormones ; against hormone releasing or inhibiting factors
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/58—Atrial natriuretic factor complex; Atriopeptin; Atrial natriuretic peptide [ANP]; Cardionatrin; Cardiodilatin
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/10—Cells modified by introduction of foreign genetic material
- C12N5/12—Fused cells, e.g. hybridomas
- C12N5/16—Animal cells
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/531—Production of immunochemical test materials
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/10—Immunoglobulins specific features characterized by their source of isolation or production
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/975—Kit
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/811—Test for named disease, body condition or organ function

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
Molecular Biology (AREA)
Engineering & Computer Science (AREA)
Immunology (AREA)
Biochemistry (AREA)
Genetics & Genomics (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Biomedical Technology (AREA)
Endocrinology (AREA)
Biophysics (AREA)
Zoology (AREA)
Hematology (AREA)
Urology & Nephrology (AREA)
Biotechnology (AREA)
Microbiology (AREA)
Cell Biology (AREA)
Gastroenterology & Hepatology (AREA)
Toxicology (AREA)
Cardiology (AREA)
Food Science & Technology (AREA)
Physics & Mathematics (AREA)
Analytical Chemistry (AREA)
General Physics & Mathematics (AREA)
Pathology (AREA)
Bioinformatics & Cheminformatics (AREA)
Wood Science & Technology (AREA)
General Engineering & Computer Science (AREA)
Peptides Or Proteins (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)

PL04732278T 2003-05-12 2004-05-12 Sposoby wykrywania proBMP przeciwciałem monoklonalnym wiążącym się z aminokwasami 38-43 PL1625163T3 (pl)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
EP03010591		2003-05-12
PCT/EP2004/005091 WO2004099252A1 (en)	2003-05-12	2004-05-12	Method of detecting native probnp with amonoclonal antibody binding to the amino acids 38-44
EP04732278A EP1625163B8 (en)	2003-05-12	2004-05-12	Method of detecting probnp with a monoclonal antibody binding to the amino acids 38-43

Publications (1)

Publication Number	Publication Date
PL1625163T3 true PL1625163T3 (pl)	2012-01-31

Family

ID=33427054

Family Applications (3)

Application Number	Title	Priority Date	Filing Date
PL04732282T PL1625164T3 (pl)	2003-05-12	2004-05-12	Sposób wykrywania proBNP z użyciem przeciwciała monoklonalnego wiążącego się z aminokwasami 42-46
PL04732278T PL1625163T3 (pl)	2003-05-12	2004-05-12	Sposoby wykrywania proBMP przeciwciałem monoklonalnym wiążącym się z aminokwasami 38-43
PL10172014T PL2256132T3 (pl)	2003-05-12	2004-05-12	Sposób wykrywania proBNP z zastosowaniem przeciwciała monoklonalnego

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
PL04732282T PL1625164T3 (pl)	2003-05-12	2004-05-12	Sposób wykrywania proBNP z użyciem przeciwciała monoklonalnego wiążącego się z aminokwasami 42-46

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
PL10172014T PL2256132T3 (pl)	2003-05-12	2004-05-12	Sposób wykrywania proBNP z zastosowaniem przeciwciała monoklonalnego

Country Status (16)

Country	Link
US (4)	US7264938B2 (pl)
EP (4)	EP2949669A1 (pl)
JP (4)	JP5128125B2 (pl)
KR (2)	KR100857752B1 (pl)
CN (3)	CN100497393C (pl)
AT (2)	ATE522546T1 (pl)
AU (1)	AU2004235974B2 (pl)
BR (1)	BRPI0410261B8 (pl)
CA (2)	CA2522378C (pl)
DK (3)	DK1625163T3 (pl)
ES (3)	ES2372282T3 (pl)
HK (1)	HK1097855A1 (pl)
HU (1)	HUE025169T2 (pl)
MX (1)	MXPA05011826A (pl)
PL (3)	PL1625164T3 (pl)
WO (2)	WO2004099252A1 (pl)

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FR2843396B1 (fr) *	2002-08-07	2005-04-15	Bio Rad Pasteur	Anticorps specifiques pour le diagnostic de l'insuffisance cardiaque
DK1625163T3 (da) *	2003-05-12	2011-12-05	Hoffmann La Roche	Fremgangsmåde til at påvise proBNP med en monoklonal antistofbinding til aminosyrerne 38-43
US20070037208A1 (en) *	2003-05-29	2007-02-15	Foote Robert S	Method for detecting cardiac ischemia via changes in b-natriuretic peptide levels
DE10355731A1 (de)	2003-11-28	2005-06-30	Roche Diagnostics Gmbh	Analytischer Sandwichtest zur Bestimmung von NT-proBNP
DE602005001299T2 (de) *	2004-07-07	2008-02-07	Roche Diagnostics Gmbh	Kombinationen von Markern zum Nachweis von typ 1 und 2 Diabetes
AT500800B1 (de) *	2004-09-08	2008-07-15	Biomedica Medizinprodukte Gmbh	Verfahren zur bestimmung von probnp
CN101636656A (zh)	2007-01-25	2010-01-27	霍夫曼-拉罗奇有限公司	Igfbp-7在心力衰竭评估中的用途
KR100836322B1 (ko) *	2007-08-31	2008-06-09	현대자동차주식회사	차량용 흡음재 제작장치 및 방법
US9482677B2 (en)	2008-02-27	2016-11-01	Scios Inc.	Method, composition and device for sampling natriuretic peptides in a biological fluid
JP5524182B2 (ja)	2008-04-30	2014-06-18	エフ．ホフマン−ラロシュアーゲー	心不全の評価におけるｓｆｒｐ−３の使用
EP2460015B1 (en)	2009-07-27	2014-08-20	Roche Diagnostics GmbH	Use of mimecan in the assessment of heart failure
EA201290311A1 (ru) *	2009-11-13	2012-12-28	БиДжи МЕДИСИН, ИНК.	Факторы риска и прогнозирование инфаркта миокарда
AU2011285694B2 (en)	2010-08-04	2014-12-18	Idexx Laboratories, Inc.	Detection of degradation products of canine NT-proBNP
WO2012166918A1 (en)	2011-05-31	2012-12-06	Idexx Laboratories, Inc.	DETECTION OF DEGRADATION PRODUCTS OF FELINE NT-proBNP
WO2013042603A1 (ja) *	2011-09-20	2013-03-28	コニカミノルタホールディングス株式会社	検体希釈用液、それを用いたキットおよび蛍光測定方法
US20140273273A1 (en)	2012-11-01	2014-09-18	Christie Mitchell Ballantyne	Biomarkers to improve prediction of heart failure risk
CN103304665A (zh) *	2013-05-21	2013-09-18	上海贝西生物科技有限公司	一种抗氨基末端脑利钠肽前体单克隆抗体及其应用
JP6682445B2 (ja) *	2014-10-10	2020-04-15	松森　昭	心不全患者の検出方法、心疾患の識別方法、心不全の検査試薬、心不全の検査キット、心不全を検出するための装置及び心不全を検出するためのプログラム
EP3360570A1 (en)	2017-02-13	2018-08-15	Roche Diagnostics GmbH	Antibodies recognizing genetic variants
US11549940B2 (en)	2017-10-02	2023-01-10	Otsuka Pharmaceutical Co., Ltd.	Method for detecting analyte
US20210148934A1 (en) *	2018-04-13	2021-05-20	Kyoritsu Seiyaku Corporation	Method of detecting heart failure, device for detecting heart failure, sandwich immunoassay method, and combination of antibodies
CN108752480B (zh) *	2018-05-30	2022-03-29	中元汇吉生物技术股份有限公司	一种免疫原组合物、其制备方法及其用途
US11931207B2 (en)	2018-12-11	2024-03-19	Eko.Ai Pte. Ltd.	Artificial intelligence (AI) recognition of echocardiogram images to enhance a mobile ultrasound device
US11446009B2 (en)	2018-12-11	2022-09-20	Eko.Ai Pte. Ltd.	Clinical workflow to diagnose heart disease based on cardiac biomarker measurements and AI recognition of 2D and doppler modality echocardiogram images
US12001939B2 (en)	2018-12-11	2024-06-04	Eko.Ai Pte. Ltd.	Artificial intelligence (AI)-based guidance for an ultrasound device to improve capture of echo image views
CN111487222B (zh) *	2019-01-28	2023-11-14	上海乐合生物科技有限公司	一种检测bnp的spr芯片的制备方法
EP4014041A1 (en)	2019-08-13	2022-06-22	Gentian AS	Highly sensitive particle enhanced assay for the quantification of nt-probnp
JP7650966B2 (ja) *	2020-09-30	2025-03-25	エフ．ホフマン－ラロシュアーゲー	心房細動の評価における、循環中の総ＮＴ－ｐｒｏＢＮＰ（グリコシル化および非グリコシル化ＮＴ－ｐｒｏＢＮＰ）ならびにそのＮＴ－ｐｒｏＢＮＰ（非グリコシル化ＮＴ－ｐｒｏＢＮＰ）との比率
CN112986586A (zh) *	2021-02-20	2021-06-18	广东菲鹏生物有限公司	一种氨基末端脑尿钠肽检测方法和试剂盒
CN112964885B (zh) *	2021-02-20	2022-11-11	广东菲鹏生物有限公司	一种氨基末端脑尿钠肽检测方法和试剂盒
CN118119849A (zh)	2021-10-01	2024-05-31	挪威金田有限公司	测定样品中N末端激素原BNP(NT-proBNP)浓度的新方法
CN118871785A (zh)	2022-03-18	2024-10-29	豪夫迈·罗氏有限公司	用于2型与1型急性心肌梗死的早期辨别的肌钙蛋白标志物组合
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JP2665850B2 (ja)	1991-11-14	1997-10-22	塩野義製薬株式会社	ｈＢＮＰのＣ端を認識するモノクロ−ナル抗体
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DK1625163T3 (da) *	2003-05-12	2011-12-05	Hoffmann La Roche	Fremgangsmåde til at påvise proBNP med en monoklonal antistofbinding til aminosyrerne 38-43

2004
- 2004-05-12 DK DK04732278.9T patent/DK1625163T3/da active
- 2004-05-12 AU AU2004235974A patent/AU2004235974B2/en not_active Expired
- 2004-05-12 ES ES04732278T patent/ES2372282T3/es not_active Expired - Lifetime
- 2004-05-12 CN CNB200480012494XA patent/CN100497393C/zh not_active Expired - Lifetime
- 2004-05-12 KR KR1020057021327A patent/KR100857752B1/ko not_active Expired - Lifetime
- 2004-05-12 CA CA2522378A patent/CA2522378C/en not_active Expired - Lifetime
- 2004-05-12 PL PL04732282T patent/PL1625164T3/pl unknown
- 2004-05-12 JP JP2006505419A patent/JP5128125B2/ja not_active Expired - Lifetime
- 2004-05-12 MX MXPA05011826A patent/MXPA05011826A/es active IP Right Grant
- 2004-05-12 CN CNA2004800124973A patent/CN1784425A/zh active Pending
- 2004-05-12 ES ES04732282T patent/ES2369008T3/es not_active Expired - Lifetime
- 2004-05-12 EP EP15161853.5A patent/EP2949669A1/en not_active Ceased
- 2004-05-12 DK DK04732282.1T patent/DK1625164T3/da active
- 2004-05-12 KR KR1020087000782A patent/KR20080011467A/ko not_active Ceased
- 2004-05-12 WO PCT/EP2004/005091 patent/WO2004099252A1/en active Application Filing
- 2004-05-12 PL PL04732278T patent/PL1625163T3/pl unknown
- 2004-05-12 EP EP04732278A patent/EP1625163B8/en not_active Expired - Lifetime
- 2004-05-12 JP JP2006505418A patent/JP4430066B2/ja not_active Expired - Lifetime
- 2004-05-12 BR BRPI0410261A patent/BRPI0410261B8/pt not_active IP Right Cessation
- 2004-05-12 DK DK10172014.2T patent/DK2256132T3/en active
- 2004-05-12 EP EP04732282A patent/EP1625164B1/en not_active Expired - Lifetime
- 2004-05-12 CN CN2010101190838A patent/CN101967190A/zh active Pending
- 2004-05-12 HU HUE10172014A patent/HUE025169T2/en unknown
- 2004-05-12 AT AT04732278T patent/ATE522546T1/de active
- 2004-05-12 WO PCT/EP2004/005092 patent/WO2004099253A1/en active Search and Examination
- 2004-05-12 EP EP10172014.2A patent/EP2256132B1/en not_active Expired - Lifetime
- 2004-05-12 ES ES10172014.2T patent/ES2548327T3/es not_active Expired - Lifetime
- 2004-05-12 AT AT04732282T patent/ATE517124T1/de active
- 2004-05-12 PL PL10172014T patent/PL2256132T3/pl unknown
- 2004-05-12 CA CA2522747A patent/CA2522747C/en not_active Expired - Lifetime
2005
- 2005-11-10 US US11/271,138 patent/US7264938B2/en not_active Expired - Lifetime
- 2005-11-10 US US11/271,651 patent/US7264939B2/en not_active Expired - Lifetime
2006
- 2006-12-05 US US11/634,286 patent/US7807380B2/en not_active Expired - Lifetime
- 2006-12-22 US US11/644,565 patent/US7811770B2/en not_active Expired - Lifetime
2007
- 2007-02-28 HK HK07102250.4A patent/HK1097855A1/xx not_active IP Right Cessation
2009
- 2009-09-04 JP JP2009204610A patent/JP4834136B2/ja not_active Expired - Lifetime
2012
- 2012-10-04 JP JP2012222436A patent/JP5649631B2/ja not_active Expired - Lifetime

Also Published As

Publication number	Publication date
ES2372282T3 (es)	2012-01-18
KR20060003905A (ko)	2006-01-11
CN101967190A (zh)	2011-02-09
MXPA05011826A (es)	2006-01-26
HUE025169T2 (en)	2016-02-29
JP5649631B2 (ja)	2015-01-07
EP1625164B1 (en)	2011-07-20
DK2256132T3 (en)	2015-07-13
BRPI0410261B1 (pt)	2020-03-10
AU2004235974A1 (en)	2004-11-18
AU2004235974B2 (en)	2008-02-14
EP2949669A1 (en)	2015-12-02
KR100857752B1 (ko)	2008-09-11
US20070117156A1 (en)	2007-05-24
CA2522378C (en)	2011-03-29
US7807380B2 (en)	2010-10-05
JP2007525427A (ja)	2007-09-06
JP5128125B2 (ja)	2013-01-23
CN1832964A (zh)	2006-09-13
CA2522378A1 (en)	2004-11-18
EP1625164A1 (en)	2006-02-15
DK1625164T3 (da)	2011-10-31
JP2010011860A (ja)	2010-01-21
CN100497393C (zh)	2009-06-10
US20060110776A1 (en)	2006-05-25
JP4430066B2 (ja)	2010-03-10
ES2369008T3 (es)	2011-11-24
PL1625164T3 (pl)	2011-12-30
US20070099241A1 (en)	2007-05-03
ES2548327T3 (es)	2015-10-15
CA2522747A1 (en)	2004-11-18
ATE522546T1 (de)	2011-09-15
BRPI0410261A (pt)	2006-05-16
PL2256132T3 (pl)	2016-08-31
BRPI0410261B8 (pt)	2021-07-27
ATE517124T1 (de)	2011-08-15
DK1625163T3 (da)	2011-12-05
KR20080011467A (ko)	2008-02-04
EP1625163B1 (en)	2011-08-31
US7264938B2 (en)	2007-09-04
EP2256132B1 (en)	2015-04-01
US7264939B2 (en)	2007-09-04
CA2522747C (en)	2012-08-14
JP2007535470A (ja)	2007-12-06
JP4834136B2 (ja)	2011-12-14
HK1097855A1 (en)	2007-07-06
US20060110775A1 (en)	2006-05-25
EP1625163B8 (en)	2011-11-02
JP2013018784A (ja)	2013-01-31
CN1784425A (zh)	2006-06-07
WO2004099252A1 (en)	2004-11-18
EP1625163A1 (en)	2006-02-15
WO2004099253A1 (en)	2004-11-18
US7811770B2 (en)	2010-10-12
EP2256132A1 (en)	2010-12-01

Publication	Publication Date	Title
PL1625163T3 (pl)	2012-01-31	Sposoby wykrywania proBMP przeciwciałem monoklonalnym wiążącym się z aminokwasami 38-43
ATE486093T1 (de)	2010-11-15	Antikörper, die spezifische für probnp(1-108) sind, und ihre verwendung zur diagnose von herzinfarkt
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DK1092155T3 (da)	2003-03-24	Fremgangsmåde til tidlig diagnose af carcinomer
JP2007525427A5 (pl)	2009-04-23
DK1151304T3 (da)	2008-01-28	Fremgangsmåde til påvisning af N-terminalt proBNP
ATE335763T1 (de)	2006-09-15	Sandwich-immunoassay zur bestimmung von proanp- teilpeptiden
WO2009075376A1 (ja)	2009-06-18	抗オフロキサシンモノクローナル抗体、これを用いたオフロキサシンの免疫学的測定方法
DE60333471D1 (de)	2010-09-02	Polyklonaler-monoklonaler-elisa-assay zum nachweis von n-terminalem probnp
WO2008125733A8 (en)	2009-07-30	Immunoassay for quantification of an unstable antigen selected from bnp and probnp
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ATE405646T1 (de)	2008-09-15	Ein verfahren zum auffinden vom prostatakrebs
WO2003027150A1 (fr)	2003-04-03	Anticorps et son utilisation
TW200720655A (en)	2007-06-01	ELISA kit for diagnosting infectious bursal disease (IBD) and method using the same