PL1651260T3 - Lawsonia intracellularis pochodzenia europejskiego oraz szczepionki, środki diagnostyczne i sposoby ją wykorzystujące - Google Patents

Lawsonia intracellularis pochodzenia europejskiego oraz szczepionki, środki diagnostyczne i sposoby ją wykorzystujące

Info

Publication number: PL1651260T3
Authority: PL; Poland
Prior art keywords: intracellularis; vaccines; methods; diagnostic agents; lawsonia intracellularis
Prior art date: 2003-07-25

Application number

PL04778282T

Other languages

English (en)

Other versions

PL1651260T5 (pl

Inventor

Michael B Roof

Jeremy J Kroll

Jeffrey P Knittel

Original Assignee

Boehringer Ingelheim Vetmedica Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2003-07-25

Filing date

2004-07-15

Publication date

2010-02-26

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34115340&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PL1651260(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2004-07-15 Application filed by Boehringer Ingelheim Vetmedica Inc filed Critical Boehringer Ingelheim Vetmedica Inc

2010-02-26 Publication of PL1651260T3 publication Critical patent/PL1651260T3/pl

2018-11-30 Publication of PL1651260T5 publication Critical patent/PL1651260T5/pl

Links

241001148567 Lawsonia intracellularis Species 0.000 title abstract 5
229960005486 vaccine Drugs 0.000 title abstract 3
229940039227 diagnostic agent Drugs 0.000 title 1
239000000032 diagnostic agent Substances 0.000 title 1
230000002238 attenuated effect Effects 0.000 abstract 1
208000015181 infectious disease Diseases 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/105—Delta proteobacteriales, e.g. Lawsonia; Epsilon proteobacteriales, e.g. campylobacter, helicobacter
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/12—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
- C07K16/1203—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
- A61K2039/521—Bacterial cells; Fungal cells; Protozoal cells inactivated (killed)
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
- A61K2039/522—Bacterial cells; Fungal cells; Protozoal cells avirulent or attenuated
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/195—Assays involving biological materials from specific organisms or of a specific nature from bacteria
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S424/00—Drug, bio-affecting and body treating compositions
- Y10S424/825—Bacterial vaccine for porcine species, e.g. swine

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Immunology (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Engineering & Computer Science (AREA)
Genetics & Genomics (AREA)
Microbiology (AREA)
Bioinformatics & Cheminformatics (AREA)
Biochemistry (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Mycology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Wood Science & Technology (AREA)
Zoology (AREA)
Biotechnology (AREA)
Chemical Kinetics & Catalysis (AREA)
Epidemiology (AREA)
Biophysics (AREA)
Molecular Biology (AREA)
Virology (AREA)
General Engineering & Computer Science (AREA)
Tropical Medicine & Parasitology (AREA)
Biomedical Technology (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

PL04778282T 2003-07-25 2004-07-15 Lawsonia intracellularis pochodzenia europejskiego oraz szczepionki, środki diagnostyczne i sposoby ją wykorzystujące PL1651260T5 (pl)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US49000103P	2003-07-25	2003-07-25
PCT/US2004/022704 WO2005011731A1 (en)	2003-07-25	2004-07-15	Lawsonia intracellularis of european origin and vaccines, diagnostic agents and methods of use thereof
EP04778282.6A EP1651260B2 (en)	2003-07-25	2004-07-15	Lawsonia intracellularis of european origin and vaccines, diagnostic agents and methods of use thereof

Publications (2)

Publication Number	Publication Date
PL1651260T3 true PL1651260T3 (pl)	2010-02-26
PL1651260T5 PL1651260T5 (pl)	2018-11-30

Family

ID=34115340

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PL04778282T PL1651260T5 (pl)	2003-07-25	2004-07-15	Lawsonia intracellularis pochodzenia europejskiego oraz szczepionki, środki diagnostyczne i sposoby ją wykorzystujące

Country Status (23)

Country	Link
US (2)	US7312065B2 (pl)
EP (1)	EP1651260B2 (pl)
JP (1)	JP2006528882A (pl)
KR (1)	KR101131845B1 (pl)
CN (2)	CN1829529B (pl)
AT (1)	ATE442163T2 (pl)
AU (1)	AU2004260657B2 (pl)
BR (1)	BRPI0412911B1 (pl)
CA (1)	CA2533559C (pl)
CY (1)	CY1109652T1 (pl)
DE (1)	DE602004023094D1 (pl)
DK (1)	DK1651260T4 (pl)
ES (1)	ES2333334T5 (pl)
MX (1)	MXPA06000994A (pl)
MY (1)	MY140208A (pl)
PL (1)	PL1651260T5 (pl)
PT (1)	PT1651260E (pl)
RU (1)	RU2420570C2 (pl)
SG (1)	SG144909A1 (pl)
SI (1)	SI1651260T2 (pl)
UA (1)	UA87665C2 (pl)
WO (1)	WO2005011731A1 (pl)
ZA (1)	ZA200510081B (pl)

Families Citing this family (41)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2772047B1 (fr) *	1997-12-05	2004-04-09	Ct Nat D Etudes Veterinaires E	Sequence genomique et polypeptides de circovirus associe a la maladie de l'amaigrissement du porcelet (map), applications au diagnostic et a la prevention et/ou au traitement de l'infection
UA95602C2 (ru)	2004-12-30	2011-08-25	Берингер Ингельхейм Ветмедика, Инк.	Иммуногенная композиция цвс2 и способы приготовления такой композиции
US7833707B2 (en)	2004-12-30	2010-11-16	Boehringer Ingelheim Vetmedica, Inc.	Methods of overexpression and recovery of porcine circovirus type 2 ORF2
AU2012207016B2 (en) *	2005-03-14	2015-01-15	Boehringer Ingelheim Animal Health USA Inc.	Immunogenic compositions comprising Lawsonia intracellularis
US8834891B2 (en)	2005-03-14	2014-09-16	Boehringer Ingelheim Vetmedica, Inc.	Immunogenic compositions comprising Lawsonia intracellularis
US8398994B2 (en) *	2005-07-15	2013-03-19	Boehringer Ingelheim Vetmedica, Inc.	Lawsonia vaccine and methods of use thereof
DK3320919T3 (da)	2005-12-29	2020-08-03	Boehringer Ingelheim Animal Health Usa Inc	Multivalente pcv2-immunogeniske sammensætninger og fremgangsmåder til at fremstille sådanne sammensætninger
DK2371383T3 (en) *	2005-12-29	2015-11-30	Boehringer Ingelheim Vetmed	Use of a PCV2 immunogenic composition for reduction of clinical symptoms in pigs
US8470336B2 (en) *	2006-05-25	2013-06-25	Boehringer Ingelheim Vetmedica, Inc.	Vaccination of young animals against Lawsonia intracellularis infections
US20080241190A1 (en) *	2006-11-13	2008-10-02	Boehringer Ingelheim Vetmedica, Inc.	Vaccination of horses against lawsonia intracellularis
EP2099927A4 (en) *	2006-11-22	2010-05-05	Boehringer Ingelheim Vetmed	Methods of reducing porcine circovirus-associated disease outbreaks
EP2859900A1 (en)	2006-12-11	2015-04-15	Boehringer Ingelheim Vetmedica, Inc.	Effective method of treatment of porcine circovirus and lawsonia intracellularis infections
PL2094872T5 (pl) *	2006-12-15	2020-10-05	Boehringer Ingelheim Animal Health USA Inc.	Leczenie świń seropozytywnych wobec przeciwciała anty-pcv2 antygenem pcv2
EP1941903A1 (en)	2007-01-03	2008-07-09	Boehringer Ingelheim Vetmedica Gmbh	Prophylaxis and treatment of PRDC
EP1958644A1 (en)	2007-02-13	2008-08-20	Boehringer Ingelheim Vetmedica Gmbh	Prevention and treatment of sub-clinical pcvd
US7829274B2 (en) *	2007-09-04	2010-11-09	Boehringer Ingelheim Vetmedica, Inc.	Reduction of concomitant infections in pigs by the use of PCV2 antigen
CL2008002675A1 (es) *	2007-09-11	2008-11-07	Wyeth Corp	Bacteria de mycoplasma gallisepticum atenuada; composicion de vacuna que la comprende; método de vacunación; y método de identificación de clones de mycoplasma gallisepticum atenuados.
EP2200643B1 (en)	2007-09-17	2013-09-04	Boehringer Ingelheim Vetmedica, Inc.	A live lawsonia intracellularis vaccine administered in combination with an antibiotic for use in the treatment of lawsonia intracellularis infections in pigs
JP2011508595A (ja) *	2007-12-31	2011-03-17	ベーリンガーインゲルハイムフェトメディカインコーポレイテッド	外来性アミノ酸の挿入を含むｐｃｖ２ｏｒｆ２ウイルス様粒子
KR20100113582A (ko)	2008-01-23	2010-10-21	베링거잉겔하임베트메디카인코퍼레이티드	Ｐｃｖ2 마이코플라즈마 히오뉴모니에 면역원성 조성물 및 당해 조성물의 생산 방법
US20110033495A1 (en) *	2008-02-15	2011-02-10	Boehringer Ingelheim Vetmedica, Inc.	Methods and compositions for reducing the impact of enteric diseases
TWI449533B (zh) *	2008-04-18	2014-08-21	Intervet Int Bv	防備胞內勞森菌（Ｌａｗｓｏｎｉａｉｎｔｒａｃｅｌｌｕｌａｒｉｓ）、豬肺炎黴漿菌（Ｍｙｃｏｐｌａｓｍａｈｙｏｐｎｅｕｍｏｎｉａｅ）及豬環狀病毒（Ｐｏｒｃｉｎｅｃｉｒｃｏｖｉｒｕｓ）用疫苗
TWI551295B (zh)	2008-04-18	2016-10-01	英特威特國際股份有限公司	防備胞內勞森菌（Ｌａｗｓｏｎｉａｉｎｔｒａｃｅｌｌｕｌａｒｉｓ）用疫苗
JP5723772B2 (ja) *	2008-07-22	2015-05-27	インターベットインターナショナルベー．フェー．	新規血清型のローソニア・イントラセルラリス細菌、その細菌に基づくワクチン、該新規ローソニア・イントラセルラリス血清型の特定に適した抗体および該抗体を製造するためのハイブリドーマ
US8142760B2 (en) *	2008-09-05	2012-03-27	Nathan Len Winkelman	Vaccination for Lawsonia intracellularis
WO2011006880A1 (en) *	2009-07-14	2011-01-20	Intervet International B.V.	Lawsonia intracellularis propagation
TWI627281B (zh)	2009-09-02	2018-06-21	百靈佳殷格翰家畜藥品公司	降低ｐｃｖ－２組合物殺病毒活性之方法及具有改良免疫原性之ｐｃｖ－２組合物
US8530223B2 (en)	2009-11-09	2013-09-10	Intervet International B.V.	Method to grow Lawsonia intracellularis bacteria in persistently infected McCoy cells
CA2793959C (en)	2010-03-25	2019-06-04	Oregon Health & Science University	Cmv glycoproteins and recombinant vectors
PT2691530T (pt)	2011-06-10	2018-05-10	Univ Oregon Health & Science	Glicoproteínas e vectores recombinantes cmv
CN105579060B (zh)	2013-09-25	2021-03-16	硕腾服务有限责任公司	Pcv2b趋异株疫苗组合物以及使用方法
AU2014329524B2 (en)	2013-10-02	2019-01-17	Boehringer Ingelheim Animal Health USA Inc.	PCV2 ORF2 protein variant and virus like particles composed thereof
RU2672251C1 (ru) *	2013-12-03	2018-11-13	Интервет Интернэшнл Б.В.	Вакцина против lawsonia intracellularis и свиного цирковируса 2-го типа
CN103823063B (zh) *	2014-02-25	2015-09-30	上海理工大学	检测猪霍乱沙门氏菌的方法及其单抗
WO2016124623A1 (en)	2015-02-04	2016-08-11	Intervet International B.V.	A vaccine for use against subclinical lawsonia infection in a pig
KR101893827B1 (ko) *	2016-01-04	2018-08-31	전북대학교 산학협력단	약독화된 살모넬라 변이주를 유효성분으로 포함하는 돼지 증식성 회장염 및 살모넬라증 동시 예방 또는 치료용 백신 조성물
AU2019228294A1 (en)	2018-02-28	2020-08-13	Boehringer Ingelheim Vetmedica Gmbh	Method for reducing skatole and/or indole in animals
KR102249189B1 (ko) *	2020-01-09	2021-05-07	전북대학교 산학협력단	항원성이 증진된 항원을 발현하는 약독화된 살모넬라 변이주를 유효성분으로 포함하는 돼지 증식성 회장염 및 살모넬라증 동시 예방 또는 치료용 백신 조성물
BR112023001324A2 (pt)	2020-07-24	2023-02-14	Boehringer Ingelheim Animal Health Usa Inc	Combinação de vacina de suíno
CN111961627A (zh) *	2020-08-27	2020-11-20	南京农业大学	一种胞内劳森菌的分离与培养方法
US20230141226A1 (en)	2021-11-01	2023-05-11	Boehringer Ingelheim Vetmedica Gmbh	Immunogenic gel compositions

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5885823A (en) *	1995-06-05	1999-03-23	Nobl Laboratories, Inc.	Lawsonia intracellularis cultivation, anti-Lawsonia intracellularis vaccines and diagnostic agents
US5714375A (en) *	1995-06-05	1998-02-03	Nobl Laboratories, Inc.	Ileal symbiont intracellularis propagation in suspended host cells

2004
- 2004-07-15 CA CA2533559A patent/CA2533559C/en not_active Expired - Lifetime
- 2004-07-15 JP JP2006521125A patent/JP2006528882A/ja active Pending
- 2004-07-15 EP EP04778282.6A patent/EP1651260B2/en not_active Expired - Lifetime
- 2004-07-15 ES ES04778282.6T patent/ES2333334T5/es not_active Expired - Lifetime
- 2004-07-15 UA UAA200601775A patent/UA87665C2/ru unknown
- 2004-07-15 CN CN200480021627XA patent/CN1829529B/zh not_active Expired - Lifetime
- 2004-07-15 WO PCT/US2004/022704 patent/WO2005011731A1/en active Application Filing
- 2004-07-15 BR BRPI0412911A patent/BRPI0412911B1/pt active IP Right Grant
- 2004-07-15 PT PT04778282T patent/PT1651260E/pt unknown
- 2004-07-15 DK DK04778282.6T patent/DK1651260T4/en active
- 2004-07-15 KR KR1020067001755A patent/KR101131845B1/ko not_active Expired - Lifetime
- 2004-07-15 DE DE602004023094T patent/DE602004023094D1/de not_active Expired - Lifetime
- 2004-07-15 PL PL04778282T patent/PL1651260T5/pl unknown
- 2004-07-15 SG SG200805019-7A patent/SG144909A1/en unknown
- 2004-07-15 SI SI200431296T patent/SI1651260T2/sl unknown
- 2004-07-15 RU RU2006105715/10A patent/RU2420570C2/ru active
- 2004-07-15 AT AT04778282T patent/ATE442163T2/de active
- 2004-07-15 US US10/891,745 patent/US7312065B2/en not_active Expired - Lifetime
- 2004-07-15 CN CNA2008101760745A patent/CN101423811A/zh active Pending
- 2004-07-15 AU AU2004260657A patent/AU2004260657B2/en not_active Expired
- 2004-07-15 MX MXPA06000994A patent/MXPA06000994A/es active IP Right Grant
- 2004-07-23 MY MYPI20042965A patent/MY140208A/en unknown
2005
- 2005-12-12 ZA ZA200510081A patent/ZA200510081B/en unknown
2007
- 2007-11-06 US US11/935,447 patent/US7758870B2/en not_active Expired - Lifetime
2009
- 2009-11-25 CY CY20091101223T patent/CY1109652T1/el unknown

Also Published As

Publication number	Publication date
EP1651260B1 (en)	2009-09-09
ATE442163T2 (de)	2009-09-15
JP2006528882A (ja)	2006-12-28
ES2333334T3 (es)	2010-02-19
RU2420570C2 (ru)	2011-06-10
US20080112980A1 (en)	2008-05-15
CN1829529B (zh)	2011-05-04
SI1651260T2 (sl)	2018-09-28
CN101423811A (zh)	2009-05-06
RU2006105715A (ru)	2007-09-10
SG144909A1 (en)	2008-08-28
CA2533559C (en)	2013-07-02
US7758870B2 (en)	2010-07-20
MY140208A (en)	2009-11-30
BRPI0412911A (pt)	2006-09-26
ZA200510081B (en)	2006-08-30
BRPI0412911B1 (pt)	2020-01-21
US20050031647A1 (en)	2005-02-10
US7312065B2 (en)	2007-12-25
CN1829529A (zh)	2006-09-06
AU2004260657B2 (en)	2012-06-07
KR101131845B1 (ko)	2012-03-30
WO2005011731A1 (en)	2005-02-10
EP1651260B2 (en)	2018-06-27
AU2004260657A1 (en)	2005-02-10
CY1109652T1 (el)	2014-08-13
DK1651260T4 (en)	2018-10-08
SI1651260T1 (sl)	2010-01-29
PL1651260T5 (pl)	2018-11-30
KR20060054352A (ko)	2006-05-22
EP1651260A1 (en)	2006-05-03
DE602004023094D1 (de)	2009-10-22
ES2333334T5 (es)	2018-08-06
DK1651260T3 (da)	2010-01-11
CA2533559A1 (en)	2005-02-10
PT1651260E (pt)	2009-09-24
UA87665C2 (ru)	2009-08-10
MXPA06000994A (es)	2006-05-15

Publication	Publication Date	Title
SI1651260T1 (sl)	2010-01-29	Lawsonia intracellularis evropskega izvora in vakcine, diagnostična sredstva in postopki za njihovo uporabo
MXPA01003557A (es)	2004-04-05	Secuencias genomicas de neisseria y metodos para su uso.
SI2351579T1 (sl)	2017-05-31	Polipeptidna cepiva za široko zaščito proti hipervirulentnim meningokoknim linijam
WO2008112344A3 (en)	2009-12-30	Extracellular matrix materials as vaccine adjuvants for diseases associated with infectious pathogens or toxins
CY1107950T1 (el)	2013-09-04	Νεϊσσεριακες συνθεσεις εμβολιου και μεθοδοι
DK1185691T3 (da)	2009-06-22	Genomiske neisseriasekvenser og fremgangmåder til anvendelse deraf
SG163598A1 (en)	2010-08-30	Lawsonia vaccine and methods of use thereof
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