PH29913A - Contraception method using competitive progesterone antagonists and novel compounds useful therein - Google Patents

Contraception method using competitive progesterone antagonists and novel compounds useful therein

Info

Publication number: PH29913A
Authority: PH; Philippines
Prior art keywords: progesterone antagonists; competitive progesterone; novel compounds; compounds useful; 11beta
Prior art date: 1992-05-12

Application number

PH46174A

Other languages

English (en)

Inventor

Krzysztof Chwalisz

Waltere Elger

Karin Schmidt-Gollwitzer

Eckhard Ottow

Ulrich Klar

Horst Michna

Original Assignee

Schering Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1992-05-12

Filing date

1993-05-11

Publication date

1996-09-16

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25914813&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PH29913(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1992-05-12 Priority claimed from DE4216004A external-priority patent/DE4216004B4/de

1992-05-12 Priority claimed from DE19924216003 external-priority patent/DE4216003A1/de

1993-05-11 Application filed by Schering Ag filed Critical Schering Ag

1996-09-16 Publication of PH29913A publication Critical patent/PH29913A/en

Links

230000002860 competitive effect Effects 0.000 title abstract 2
239000000044 progesterone antagonist Substances 0.000 title abstract 2
150000001875 compounds Chemical class 0.000 title 1
230000002411 adverse Effects 0.000 abstract 1
230000015572 biosynthetic process Effects 0.000 abstract 1
230000002357 endometrial effect Effects 0.000 abstract 1
210000003754 fetus Anatomy 0.000 abstract 1
210000004907 gland Anatomy 0.000 abstract 1
230000002401 inhibitory effect Effects 0.000 abstract 1
230000016087 ovulation Effects 0.000 abstract 1
230000027758 ovulation cycle Effects 0.000 abstract 1
150000003431 steroids Chemical class 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/18—Feminine contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J53/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by condensation with a carbocyclic rings or by formation of an additional ring by means of a direct link between two ring carbon atoms, including carboxyclic rings fused to the cyclopenta(a)hydrophenanthrene skeleton are included in this class
- C07J53/002—Carbocyclic rings fused

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
General Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Epidemiology (AREA)
Organic Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Endocrinology (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Reproductive Health (AREA)
Diabetes (AREA)
Gynecology & Obstetrics (AREA)
Steroid Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Investigation Of Foundation Soil And Reinforcement Of Foundation Soil By Compacting Or Drainage (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Nozzles (AREA)
Mixers With Rotating Receptacles And Mixers With Vibration Mechanisms (AREA)
Orthopedics, Nursing, And Contraception (AREA)

PH46174A 1992-05-12 1993-05-11 Contraception method using competitive progesterone antagonists and novel compounds useful therein PH29913A (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DE4216004A DE4216004B4 (de)	1992-05-12	1992-05-12	Verwendung kompetitiver Progesteronantagonisten
DE19924216003 DE4216003A1 (de)	1992-05-12	1992-05-12	Dissoziierte kompetitive Progesteronantagonisten

Publications (1)

Publication Number	Publication Date
PH29913A true PH29913A (en)	1996-09-16

Family

ID=25914813

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PH46174A PH29913A (en)	1992-05-12	1993-05-11	Contraception method using competitive progesterone antagonists and novel compounds useful therein

Country Status (29)

Country	Link
US (5)	US5439913A (fr)
EP (1)	EP0639970B2 (fr)
JP (1)	JPH07506582A (fr)
KR (1)	KR100253922B1 (fr)
CN (1)	CN1059446C (fr)
AT (1)	ATE162712T1 (fr)
AU (1)	AU687000B2 (fr)
BG (1)	BG61965B1 (fr)
BR (1)	BR9306354A (fr)
CA (1)	CA2135608C (fr)
CZ (1)	CZ290612B6 (fr)
DE (1)	DE69316747T3 (fr)
DK (1)	DK0639970T4 (fr)
ES (1)	ES2114605T5 (fr)
FI (1)	FI112167B (fr)
GR (1)	GR3026316T3 (fr)
HU (1)	HUT68061A (fr)
IL (1)	IL105684A (fr)
MX (1)	MX9302748A (fr)
MY (1)	MY108866A (fr)
NO (1)	NO307691B1 (fr)
NZ (1)	NZ252154A (fr)
PH (1)	PH29913A (fr)
PL (1)	PL173337B1 (fr)
RO (1)	RO116769B1 (fr)
RU (1)	RU2137476C1 (fr)
SK (1)	SK282531B6 (fr)
UA (1)	UA39934C2 (fr)
WO (1)	WO1993023020A1 (fr)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
MX9301121A (es)	1992-03-02	1993-09-01	Schering Ag	Metodo y equipo para la contracepcion oral y regulacion de la menstruacion con estrogeno/progestina/aniprogestina.
US7704983B1 (en)	1992-03-02	2010-04-27	Eastern Virginia Medical School	Antiprogestin method for reducing side effects associated with low dosage HRT and oral contraception
US5439913A (en) *	1992-05-12	1995-08-08	Schering Aktiengesellschaft	Contraception method using competitive progesterone antagonists and novel compounds useful therein
DE4344463A1 (de) *	1993-12-22	1995-06-29	Schering Ag	Kombinationsprodukt zur Kontrazeption
FR2718138B1 (fr) *	1994-04-01	1996-04-26	Roussel Uclaf	Nouveaux stéroïdes comportant en position 20 une chaîne aminosubstituée, procédé et intermédiaires de préparation, application comme médicaments et compositions pharmaceutiques les renfermant.
DE4417880A1 (de) *	1994-05-18	1995-11-23	Schering Ag	19,11beta-Überbrückte 18-Nor-Steroide, Verfahren zu ihrer Herstellung, diese Steroide enthaltende Arzneimittel sowie deren Verwendung zur Herstellung von Arzneimitteln
IL115738A (en) *	1994-10-24	2002-05-23	Schering Ag	Competitive progesterone antagonists for regulating female fertility as required
ZA9510926B (en)	1994-12-23	1996-07-03	Schering Ag	Compounds with progesterone-antagonistic and antiestrogenic action to be used together for female contraception
DE19652408C2 (de) *	1996-12-06	2002-04-18	Schering Ag	Steroidester, Verfahren zu ihrer Herstellung und ihre Verwendung zur Herstellung von Arzneimitteln
CA2255130A1 (fr)	1997-12-16	1999-06-16	Archer Daniels Midland Company	Procede de fabrication d'aliments complementaires granules de l-lysine
US20020169205A1 (en) *	1998-09-29	2002-11-14	Krzysztof Chwalisz	Implantation rates after in vitro fertilization, and treatment of infertility and early pregnancy loss with a nitric oxide donor or substrate alone or in combination with progesterone, and a method for contraception with nitric oxide inhibitors in combination with antiprogestins or other agents
EE200200103A (et)	1999-08-31	2003-04-15	Jenapharm Gmbh & Co. Kg	Mesoprogestiinid (progesterooniretseptori modulaatorid) naise kontratseptiivide komponendina
US7317027B2 (en) *	2003-05-19	2008-01-08	Sanofi-Aventis Deutschland Gmbh	Azaindole-derivatives as factor Xa inhibitors
JP2007507534A (ja) *	2003-10-01	2007-03-29	ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ	持続的三相避妊方法
US20060205700A1 (en) *	2005-03-09	2006-09-14	May Flavia S	Non invasive method for prevention and treatment of cancer
MX343130B (es)	2006-10-24	2016-10-26	Repros Therapeutics Inc	Composiciones y métodos para suprimir la proliferación endometrial.
DE102007023614A1 (de)	2007-05-21	2008-11-27	Bayer Schering Pharma Aktiengesellschaft	Nichtsteroidale Progesteronrezeptor-Modulatoren
DE102007049630A1 (de)	2007-10-11	2009-10-29	Bayer Schering Pharma Aktiengesellschaft	Nichtsteroidale Progesteronrezeptor-Modulatoren
DE102007032800A1 (de)	2007-07-10	2009-01-15	Bayer Schering Pharma Aktiengesellschaft	Nichtsteroidale Progesteronrezeptor-Modulatoren
DE102007058747A1 (de)	2007-12-05	2009-06-10	Bayer Schering Pharma Aktiengesellschaft	Nichtsteroidale Progesteronrezeptor-Modulatoren
EP2070909A1 (fr)	2007-12-15	2009-06-17	Bayer Schering Pharma AG	Modulateurs de récepteur de progestérone non stéroïdiens
TWI477276B (zh) *	2008-04-28	2015-03-21	Repros Therapeutics Inc	抗黃體素給藥方案
TWI539953B (zh)	2008-04-28	2016-07-01	瑞波若斯治療學公司	用於治療乳癌之組成物和方法
AU2010348967C1 (en)	2010-03-22	2016-04-28	Allergan pharmaceuticals International Ltd.	Compositions and methods for non-toxic delivery of antiprogestins
EP2576582B1 (fr)	2010-05-26	2019-09-18	Corcept Therapeutics, Inc.	Traitement de la dystrophie musculaire
US9381193B2 (en) *	2011-04-01	2016-07-05	Washington University	Contraceptive methods and compositions
EP2868321A1 (fr)	2013-11-03	2015-05-06	Flamina Holding AG	Composition ou groupe des compositions pour l'inhibitation de la production de HCG autocrine dans la cellulse adulte humain
US9603856B2 (en)	2013-11-03	2017-03-28	Flamina Holding Ag	Pharmaceutical composition or group of compositions for inhibiting autocrine HCG production in adult human cells
CA2977591A1 (fr)	2015-03-02	2016-09-09	Corcept Therapeutics, Inc.	Utilisation d'un antagoniste du recepteur des glucocorticoides et d'analogues de la somatostatine pour le traitement de tumeurs secretant de l'hormone adrenocorticotrope (acth)
CN107530339B (zh)	2015-03-30	2021-03-16	科赛普特治疗学股份有限公司	糖皮质激素受体拮抗剂联合糖皮质激素用于治疗肾上腺功能不全
MX383318B (es)	2015-08-13	2025-03-13	Corcept Therapeutics Inc	Metodo para diagnosticar de manera diferencial el sindrome de cushing dependiente de la corticotropina.
SG11201806101SA (en)	2016-01-19	2018-08-30	Corcept Therapeutics Inc	Differential diagnosis of ectopic cushing's syndrome
SG11201908790PA (en)	2017-03-31	2019-10-30	Corcept Therapeutics Inc	Glucocorticoid receptor modulators to treat cervical cancer
EP3641780A4 (fr)	2017-06-20	2021-02-24	Corcept Therapeutics, Inc.	Méthodes de traitement des tumeurs neuro-épithéliales à l'aide de modulateurs sélectifs du récepteur de glucocorticoïdes
US20240269280A1 (en)	2020-12-18	2024-08-15	Instil Bio (Uk) Limited	Processing of tumor infiltrating lymphocytes

Family Cites Families (42)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE219447C (fr) *
DE283428C (fr) *	1913-12-10	1915-04-15
US3890356A (en)	1973-03-26	1975-06-17	Richardson Merrell Inc	7-Alkyl-{66 {hu 3,5{b -steroids
US4000273A (en)	1973-11-01	1976-12-28	Richardson-Merrell Inc.	Method for the control of fertility
US3928398A (en)	1973-11-01	1975-12-23	Richardson Merrell Inc	Derivatives of 7{60 -methylestr-4-en-3{60 ,17{62 -diol
US4352751A (en)	1979-09-10	1982-10-05	Analytical Radiation Corporation	Species-linked diamine triacetic acids and their chelates
US4416622A (en) *	1980-11-25	1983-11-22	F. L. Smidth & Co.	Method and plant such as a kiln plant for treating granular or pulverous raw material
ZA8231B (en)	1981-01-09	1982-11-24	Roussel Uclaf	New 11 -substituted steroid derivatives, their preparation, their use as medicaments, the compositions containing them and the new intermediates thus obtained
US4957939A (en)	1981-07-24	1990-09-18	Schering Aktiengesellschaft	Sterile pharmaceutical compositions of gadolinium chelates useful enhancing NMR imaging
US4647447A (en)	1981-07-24	1987-03-03	Schering Aktiengesellschaft	Diagnostic media
US4416822A (en)	1982-07-09	1983-11-22	The Upjohn Company	17β-Difluoromethyl steroids
IL68222A (en)	1983-03-24	1987-02-27	Yeda Res & Dev	Contraceptive compositions comprising a progesterone antagonist and a blocker of progesterone activity
ES533260A0 (es)	1983-06-15	1985-02-01	Schering Ag	Procedimiento para la preparacion de 13a-alquilgonanos
DE3324235A1 (de)	1983-07-01	1985-01-10	Schering AG, 1000 Berlin und 4709 Bergkamen	Neue komplexbildner, komplexe und komplexsalze
AU572589B2 (en)	1983-12-14	1988-05-12	Upjohn Company, The	11(alpha)-difluoromethyl and (e)-and (z)-11-fluoromethylene steroids
DE3347126A1 (de)	1983-12-22	1985-07-11	Schering AG, 1000 Berlin und 4709 Bergkamen	11ss-aryl-estradiene, deren herstellung und diese enthaltende pharmazeutische praeparate
US4687659A (en)	1984-11-13	1987-08-18	Salutar, Inc.	Diamide-DTPA-paramagnetic contrast agents for MR imaging
US4859451A (en)	1984-10-04	1989-08-22	Salutar, Inc.	Paramagnetic contrast agents for MR imaging
US5087439A (en)	1984-11-13	1992-02-11	Salutar, Inc.	Paramagnetic metal-diethylenetriamine-pentaacetic acid partial amide complexes for magnetic resonance imaging
US4826673A (en)	1985-01-09	1989-05-02	Mallinckrodt, Inc.	Methods and compositions for enhancing magnetic resonance imaging
DE3533175A1 (de) *	1985-09-13	1987-03-19	Schering Ag	Antigestagene zur verschiebung der endometrialen reifung
FR2598083B1 (fr) *	1986-05-05	1989-12-29	Theramex Laboratoire	Nouvelles compositions pharmaceutiques a action antiprogesteronique et leur procede d'obtention
DE3625315A1 (de)	1986-07-25	1988-01-28	Schering Ag	11ss-(4-isopropenylphenyl)-estra-4,9-diene, deren herstellung und diese enthaltende pharmazeutische praeparate
US5039512A (en)	1986-08-04	1991-08-13	Salutar, Inc.	NMR imaging with paramagnetic polyvalent metal salts of poly-(acid-alkylene-amino)-alkanes
DE3640708C2 (de)	1986-11-28	1995-05-18	Schering Ag	Verbesserte metallhaltige Pharmazeutika
DE3708942A1 (de) *	1987-03-18	1988-09-29	Schering Ag	19,11ss-ueberbrueckte steroide, deren herstellung und diese enthaltende pharmazeutische praeparate
US4994259A (en)	1987-05-08	1991-02-19	Salutar, Inc.	Improvement in the method of NMR imaging employing a manganese II chelates of N,N'-bis[pyridoxal-alkylene (or cycloalkylene) (or arylene)]-N,N'-diacetic acid derivatives
FI900218A0 (fi)	1987-07-16	1990-01-15	Nycomed As	Aminokarboxylsyror och deras derivat.
US5399340A (en)	1987-09-24	1995-03-21	Schering Aktiengesellschaft	Use of amide complex compounds
DE3805064A1 (de) *	1988-02-18	1989-10-05	Hoechst Ag	Pharmazeutische zubereitungen zur geburtseinleitung, fuer den schwangerschaftsabbruch und zur verwendung als kontrazeptivum
US5137711A (en)	1988-07-19	1992-08-11	Mallickrodt Medical, Inc.	Paramagnetic dtpa and edta alkoxyalkylamide complexes as mri agents
US5011925A (en)	1989-03-09	1991-04-30	Mallinckrodt, Inc.	Morpholinoamido EDTA derivatives
US5384108A (en)	1989-04-24	1995-01-24	Mallinckrodt Medical, Inc.	Magnetic resonance imaging agents
US5087440A (en)	1989-07-31	1992-02-11	Salutar, Inc.	Heterocyclic derivatives of DTPA used for magnetic resonance imaging
GB8923843D0 (en)	1989-10-23	1989-12-13	Salutar Inc	Compounds
US5077037A (en)	1990-08-03	1991-12-31	Mallinckrodt Medical, Inc.	Novel compositions for magnetic resonance imaging
US5407928A (en)	1990-08-15	1995-04-18	Schering Aktiengesellschaft	11β-aryl-gona-4,9-dien-3-ones
IE71203B1 (en)	1990-12-13	1997-02-12	Akzo Nv	Low estrogen oral contraceptives
US5439913A (en)	1992-05-12	1995-08-08	Schering Aktiengesellschaft	Contraception method using competitive progesterone antagonists and novel compounds useful therein
WO1993021926A1 (fr)	1992-05-06	1993-11-11	Medical College Of Hampton Roads	Reduction des hemorragies uterines secondaires liees a la prise de progesterone
US5330743A (en)	1992-11-12	1994-07-19	Magnetic Research, Inc.	Aminosaccharide contrast agents for magnetic resonance images
US5516769A (en)	1993-02-19	1996-05-14	The Medical College Of Hampton Roads	Method of inhibiting fertilization

1992
- 1992-07-01 US US07/907,514 patent/US5439913A/en not_active Expired - Lifetime
1993
- 1993-05-11 MX MX9302748A patent/MX9302748A/es not_active IP Right Cessation
- 1993-05-11 PH PH46174A patent/PH29913A/en unknown
- 1993-05-12 AT AT93909968T patent/ATE162712T1/de not_active IP Right Cessation
- 1993-05-12 CZ CZ19942780A patent/CZ290612B6/cs not_active IP Right Cessation
- 1993-05-12 WO PCT/EP1993/001181 patent/WO1993023020A1/fr active IP Right Grant
- 1993-05-12 DK DK93909968T patent/DK0639970T4/da active
- 1993-05-12 CA CA002135608A patent/CA2135608C/fr not_active Expired - Fee Related
- 1993-05-12 RU RU94046068A patent/RU2137476C1/ru not_active IP Right Cessation
- 1993-05-12 BR BR9306354A patent/BR9306354A/pt not_active Application Discontinuation
- 1993-05-12 DE DE69316747T patent/DE69316747T3/de not_active Expired - Fee Related
- 1993-05-12 ES ES93909968T patent/ES2114605T5/es not_active Expired - Lifetime
- 1993-05-12 IL IL10568493A patent/IL105684A/en not_active IP Right Cessation
- 1993-05-12 NZ NZ252154A patent/NZ252154A/en not_active IP Right Cessation
- 1993-05-12 JP JP5519879A patent/JPH07506582A/ja active Pending
- 1993-05-12 RO RO94-01791A patent/RO116769B1/ro unknown
- 1993-05-12 CN CN93107323A patent/CN1059446C/zh not_active Expired - Fee Related
- 1993-05-12 HU HU9403253A patent/HUT68061A/hu unknown
- 1993-05-12 EP EP93909968A patent/EP0639970B2/fr not_active Expired - Lifetime
- 1993-05-12 MY MYPI93000880A patent/MY108866A/en unknown
- 1993-05-12 AU AU40673/93A patent/AU687000B2/en not_active Ceased
- 1993-05-12 PL PL93306094A patent/PL173337B1/pl not_active IP Right Cessation
- 1993-05-12 SK SK1347-94A patent/SK282531B6/sk unknown
- 1993-12-05 UA UA94105922A patent/UA39934C2/uk unknown
1994
- 1994-11-10 FI FI945289A patent/FI112167B/fi active
- 1994-11-11 BG BG99178A patent/BG61965B1/bg unknown
- 1994-11-11 KR KR1019940704038A patent/KR100253922B1/ko not_active Expired - Fee Related
- 1994-11-11 NO NO944308A patent/NO307691B1/no unknown
1998
- 1998-03-11 GR GR980400507T patent/GR3026316T3/el unknown
- 1998-09-17 US US09/154,755 patent/US6340688B1/en not_active Expired - Fee Related
2001
- 2001-11-28 US US09/994,781 patent/US6608074B2/en not_active Expired - Fee Related
2003
- 2003-03-31 US US10/401,598 patent/US6790853B2/en not_active Expired - Fee Related
2004
- 2004-07-15 US US10/891,180 patent/US7297702B2/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
IL105684A0 (en)	1993-09-22
DE69316747D1 (de)	1998-03-05
EP0639970B1 (fr)	1998-01-28
US20050026885A1 (en)	2005-02-03
HUT68061A (en)	1995-05-29
PL173337B1 (pl)	1998-02-27
CZ290612B6 (cs)	2002-09-11
CZ278094A3 (en)	1995-02-15
MY108866A (en)	1996-11-30
MX9302748A (es)	1994-02-28
DK0639970T3 (da)	1998-09-21
ATE162712T1 (de)	1998-02-15
AU687000B2 (en)	1998-02-19
US5439913A (en)	1995-08-08
NO307691B1 (no)	2000-05-15
WO1993023020A1 (fr)	1993-11-25
SK282531B6 (sk)	2002-10-08
FI945289L (fi)	1994-11-10
BR9306354A (pt)	1998-06-30
DE69316747T2 (de)	1998-09-24
US20030191102A1 (en)	2003-10-09
RU94046068A (ru)	1996-10-20
ES2114605T3 (es)	1998-06-01
CA2135608A1 (fr)	1993-11-25
SK134794A3 (en)	1998-05-06
UA39934C2 (uk)	2001-07-16
IL105684A (en)	1998-08-16
FI112167B (fi)	2003-11-14
RU2137476C1 (ru)	1999-09-20
CN1087643A (zh)	1994-06-08
AU4067393A (en)	1993-12-13
JPH07506582A (ja)	1995-07-20
DK0639970T4 (da)	2003-02-10
NO944308L (no)	1995-01-11
EP0639970A1 (fr)	1995-03-01
FI945289A0 (fi)	1994-11-10
DE69316747T3 (de)	2003-04-10
US6790853B2 (en)	2004-09-14
KR100253922B1 (en)	2000-09-01
ES2114605T5 (es)	2003-04-16
EP0639970B2 (fr)	2002-11-06
CA2135608C (fr)	2007-04-10
RO116769B1 (ro)	2001-06-29
NO944308D0 (no)	1994-11-11
US6608074B2 (en)	2003-08-19
US7297702B2 (en)	2007-11-20
CN1059446C (zh)	2000-12-13
US6340688B1 (en)	2002-01-22
BG99178A (bg)	1995-05-31
NZ252154A (en)	1996-04-26
BG61965B1 (bg)	1998-11-30
US20020058649A1 (en)	2002-05-16
GR3026316T3 (en)	1998-06-30

Publication	Publication Date	Title
KR100253922B1 (en)	2000-09-01	Contraception method using competitive progesterone antagonists and novel compounds useful therein
EP0136011A3 (fr)	1986-07-16	Méthode de traitement hormonal de troubles de la périménopause, ménopause et postménopause et emballage à préparations multiples dans ce but
IL124459A0 (en)	1998-12-06	Antagonists of gonadotropin releasing hormone
MX9804850A (es)	1998-09-30	Antagonistas de hormona liberadora de gonadotropina.
PH23373A (en)	1989-07-14	Multistage combination preparation and its use for oral contraception
NO962663D0 (no)	1996-06-21	Fremgangsmåte for hormonell prevensjon
ZA919732B (en)	1992-09-30	Progestogen-only contraceptive
BG101427A (en)	1997-11-28	Competitive progesterone antagonists for regulating female fertility as required
EP1159965A3 (fr)	2002-05-22	Procédé de prévention ou d'inhibition de la fertilisation
MX9804819A (es)	1998-10-31	Antagonistas de hormona liberadora de gonadotropina.