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GR3036813T3 - Novel n-(1-alkyl-5-phenyl-2,3,4,5-tetrahydro-1h-benzo[b][1,4]diazepin-3-yl)-acetamides - Google Patents

Novel n-(1-alkyl-5-phenyl-2,3,4,5-tetrahydro-1h-benzo[b][1,4]diazepin-3-yl)-acetamides

Info

Publication number
GR3036813T3
GR3036813T3 GR20010401426T GR20010401426T GR3036813T3 GR 3036813 T3 GR3036813 T3 GR 3036813T3 GR 20010401426 T GR20010401426 T GR 20010401426T GR 20010401426 T GR20010401426 T GR 20010401426T GR 3036813 T3 GR3036813 T3 GR 3036813T3
Authority
GR
Greece
Prior art keywords
novel
diazepin
acetamides
benzo
tetrahydro
Prior art date
Application number
GR20010401426T
Other languages
English (en)
Inventor
David A Claremon
Nigel Liverton
Harold G Selnick
Garry R Smith
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of GR3036813T3 publication Critical patent/GR3036813T3/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/12—1,5-Benzodiazepines; Hydrogenated 1,5-benzodiazepines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
GR20010401426T 1995-06-07 2001-10-05 Novel n-(1-alkyl-5-phenyl-2,3,4,5-tetrahydro-1h-benzo[b][1,4]diazepin-3-yl)-acetamides GR3036813T3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US47653495A 1995-06-07 1995-06-07
PCT/US1996/008331 WO1996040653A1 (en) 1995-06-07 1996-06-03 Novel n-(1-alkyl-5-phenyl-2,3,4,5-tetrahydro-1h-benzo[b][1,4]diazepin-3-yl)-acetamides

Publications (1)

Publication Number Publication Date
GR3036813T3 true GR3036813T3 (en) 2002-01-31

Family

ID=23892257

Family Applications (1)

Application Number Title Priority Date Filing Date
GR20010401426T GR3036813T3 (en) 1995-06-07 2001-10-05 Novel n-(1-alkyl-5-phenyl-2,3,4,5-tetrahydro-1h-benzo[b][1,4]diazepin-3-yl)-acetamides

Country Status (12)

Country Link
US (1) US5726171A (el)
EP (1) EP0830350B1 (el)
JP (1) JPH11506745A (el)
AT (1) ATE206409T1 (el)
AU (1) AU704592B2 (el)
CA (1) CA2222330A1 (el)
DE (1) DE69615682T2 (el)
DK (1) DK0830350T3 (el)
ES (1) ES2163638T3 (el)
GR (1) GR3036813T3 (el)
PT (1) PT830350E (el)
WO (1) WO1996040653A1 (el)

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EP0977772A1 (en) 1997-04-14 2000-02-09 Cor Therapeutics, Inc. SELECTIVE FACTOR Xa INHIBITORS
US6228854B1 (en) 1997-08-11 2001-05-08 Cor Therapeutics, Inc. Selective factor Xa inhibitors
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US6958330B1 (en) 1998-06-22 2005-10-25 Elan Pharmaceuticals, Inc. Polycyclic α-amino-ε-caprolactams and related compounds
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US6552013B1 (en) 1998-06-22 2003-04-22 Elan Pharmaceuticals, Inc. Deoxyamino acid compounds, pharmaceutical compositions comprising same, and methods for inhibiting β-amyloid peptide release and/or its synthesis by use of such compounds
US6774125B2 (en) 1998-06-22 2004-08-10 Elan Pharmaceuticals, Inc. Deoxyamino acid compounds, pharmaceutical compositions comprising same, and methods for inhibiting β-amyloid peptide release and/or its synthesis by use of such compounds
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US6569851B1 (en) 1998-06-22 2003-05-27 Elan Pharmaceutials, Inc. Cycloalkyl, lactam, lactone and related compounds, pharmaceutical compositions comprising same, and methods for inhibiting β-amyloid peptide release and/or its synthesis by use of such compounds
US20100009966A1 (en) * 2001-04-11 2010-01-14 Bristol-Myers Squibb Pharma Company Substituted lactams as inhibitors of abeta protein production
AU2001257006A1 (en) * 2000-04-11 2001-10-23 Du Pont Pharmaceuticals Company Substituted lactams as inhibitors of abeta protein production
US20030129186A1 (en) 2001-07-25 2003-07-10 Biomarin Pharmaceutical Inc. Compositions and methods for modulating blood-brain barrier transport
EP2392258B1 (en) 2005-04-28 2014-10-08 Proteus Digital Health, Inc. Pharma-informatics system
JP2010503710A (ja) 2006-09-18 2010-02-04 ラプトール ファーマシューティカル インコーポレイテッド 受容体関連タンパク質（ｒａｐ）結合体の投与による肝障害の処置
EP3395372B1 (en) 2009-02-20 2022-04-06 EnhanX Biopharm Inc. Glutathione-based drug delivery system
BRPI1011188B1 (pt) 2009-05-06 2019-10-15 Laboratory Skin Care, Inc. Composições de liberação dérmica compreendendo complexos de partículas de agente ativo-fosfato de cálcio e métodos para usar as mesmas
US20120077778A1 (en) 2010-09-29 2012-03-29 Andrea Bourdelais Ladder-Frame Polyether Conjugates
CN118994190A (zh) 2016-02-05 2024-11-22 戴纳立制药公司 受体相互作用蛋白激酶1的抑制剂
HRP20220636T1 (hr) 2016-12-09 2022-07-22 Denali Therapeutics Inc. Spojevi korisni kao inhibitori ripk1
MX2024008648A (es) 2022-01-12 2024-09-23 Denali Therapeutics Inc Formas cristalinas de (s)-5-bencil-n-(5-metil-4-oxo-2,3,4,5-tetrah idropirido [3,2- b][1,4]oxacepin-3-il)-4h-1,2,4-triazol-3-carboxam ida.

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Also Published As

Publication number Publication date
US5726171A (en) 1998-03-10
WO1996040653A1 (en) 1996-12-19
AU5886496A (en) 1996-12-30
EP0830350A4 (en) 1998-09-30
ES2163638T3 (es) 2002-02-01
DE69615682T2 (de) 2002-07-11
ATE206409T1 (de) 2001-10-15
PT830350E (pt) 2002-02-28
DE69615682D1 (de) 2001-11-08
AU704592B2 (en) 1999-04-29
EP0830350B1 (en) 2001-10-04
DK0830350T3 (da) 2001-11-19
JPH11506745A (ja) 1999-06-15
CA2222330A1 (en) 1996-12-19
EP0830350A1 (en) 1998-03-25

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