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FR2739031B1 - Systeme matriciel transdermique d'administration d'un oestrogene et/ou d'un progestatif a base de copolymere styrene-isoprene-styrene, procede de preparation et utilisation en therapeutique - Google Patents

Systeme matriciel transdermique d'administration d'un oestrogene et/ou d'un progestatif a base de copolymere styrene-isoprene-styrene, procede de preparation et utilisation en therapeutique

Info

Publication number
FR2739031B1
FR2739031B1 FR9511325A FR9511325A FR2739031B1 FR 2739031 B1 FR2739031 B1 FR 2739031B1 FR 9511325 A FR9511325 A FR 9511325A FR 9511325 A FR9511325 A FR 9511325A FR 2739031 B1 FR2739031 B1 FR 2739031B1
Authority
FR
France
Prior art keywords
styrene
progestive
estrogen
isoprene
administration
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR9511325A
Other languages
English (en)
Other versions
FR2739031A1 (fr
Inventor
Chantal Bon Lapillonne
Mayer Daniel Dhuique
Claude Mikler
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Laboratoires dHygiene et de Dietetique SA
Original Assignee
Laboratoires dHygiene et de Dietetique SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to FR9511325A priority Critical patent/FR2739031B1/fr
Application filed by Laboratoires dHygiene et de Dietetique SA filed Critical Laboratoires dHygiene et de Dietetique SA
Priority to AU71351/96A priority patent/AU7135196A/en
Priority to CA002233171A priority patent/CA2233171A1/fr
Priority to PCT/FR1996/001496 priority patent/WO1997011689A1/fr
Priority to EP96932649A priority patent/EP0852493A1/fr
Priority to CN96197186A priority patent/CN1197389A/zh
Priority to US09/043,726 priority patent/US6007835A/en
Priority to JP9513183A priority patent/JPH11514989A/ja
Publication of FR2739031A1 publication Critical patent/FR2739031A1/fr
Application granted granted Critical
Publication of FR2739031B1 publication Critical patent/FR2739031B1/fr
Priority to NO981315A priority patent/NO981315L/no
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7076—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising ingredients of undetermined constitution or reaction products thereof, e.g. rosin or other plant resins

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Botany (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FR9511325A 1995-09-27 1995-09-27 Systeme matriciel transdermique d'administration d'un oestrogene et/ou d'un progestatif a base de copolymere styrene-isoprene-styrene, procede de preparation et utilisation en therapeutique Expired - Fee Related FR2739031B1 (fr)

Priority Applications (9)

Application Number Priority Date Filing Date Title
FR9511325A FR2739031B1 (fr) 1995-09-27 1995-09-27 Systeme matriciel transdermique d'administration d'un oestrogene et/ou d'un progestatif a base de copolymere styrene-isoprene-styrene, procede de preparation et utilisation en therapeutique
CA002233171A CA2233171A1 (fr) 1995-09-27 1996-09-25 Systeme matriciel transdermique
PCT/FR1996/001496 WO1997011689A1 (fr) 1995-09-27 1996-09-25 Systeme matriciel transdermique
EP96932649A EP0852493A1 (fr) 1995-09-27 1996-09-25 Systeme matriciel transdermique
AU71351/96A AU7135196A (en) 1995-09-27 1996-09-25 Transdermal matrix system
CN96197186A CN1197389A (zh) 1995-09-27 1996-09-25 透皮基质系统
US09/043,726 US6007835A (en) 1995-09-27 1996-09-25 Transdermal matrix system
JP9513183A JPH11514989A (ja) 1995-09-27 1996-09-25 経皮マトリックスシステム
NO981315A NO981315L (no) 1995-09-27 1998-03-23 Transdermalt matrikssystem

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9511325A FR2739031B1 (fr) 1995-09-27 1995-09-27 Systeme matriciel transdermique d'administration d'un oestrogene et/ou d'un progestatif a base de copolymere styrene-isoprene-styrene, procede de preparation et utilisation en therapeutique

Publications (2)

Publication Number Publication Date
FR2739031A1 FR2739031A1 (fr) 1997-03-28
FR2739031B1 true FR2739031B1 (fr) 1997-11-21

Family

ID=9482960

Family Applications (1)

Application Number Title Priority Date Filing Date
FR9511325A Expired - Fee Related FR2739031B1 (fr) 1995-09-27 1995-09-27 Systeme matriciel transdermique d'administration d'un oestrogene et/ou d'un progestatif a base de copolymere styrene-isoprene-styrene, procede de preparation et utilisation en therapeutique

Country Status (9)

Country Link
US (1) US6007835A (fr)
EP (1) EP0852493A1 (fr)
JP (1) JPH11514989A (fr)
CN (1) CN1197389A (fr)
AU (1) AU7135196A (fr)
CA (1) CA2233171A1 (fr)
FR (1) FR2739031B1 (fr)
NO (1) NO981315L (fr)
WO (1) WO1997011689A1 (fr)

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US5656286A (en) * 1988-03-04 1997-08-12 Noven Pharmaceuticals, Inc. Solubility parameter based drug delivery system and method for altering drug saturation concentration
US6979697B1 (en) 1998-08-21 2005-12-27 Point Therapeutics, Inc. Regulation of substrate activity
US7384650B2 (en) * 1999-11-24 2008-06-10 Agile Therapeutics, Inc. Skin permeation enhancement composition for transdermal hormone delivery system
DE10211832A1 (de) * 2002-03-16 2003-10-02 Lohmann Therapie Syst Lts Hormonhaltiges transdermales therapeutisches System mit einem Wirkstoffreservoir auf der Basis von Vinylacetat-Vinylpyrrolidon-Copolymer mit verbesserter Kohäsion
US20050191339A1 (en) * 2002-08-08 2005-09-01 Beiersdorf Ag Skin friendly active ingredient plaster based on SBC, containing at least 34 WT.% of a pharmaceutical active ingredient and production thereof
DE10236319A1 (de) * 2002-08-08 2004-02-19 Beiersdorf Ag Hautfreundliche Wirkstoffpflaster auf der Basis von SBC mit mindestens einem pharmazeutischen Wirkstoff mit einem Gehalt von mindestens 34 Gew.-% und dessen Herstellung
JP4422430B2 (ja) * 2003-05-14 2010-02-24 帝國製薬株式会社 エストロゲン及び／又はプロゲストゲン含有外用貼付剤
EP1498133A1 (fr) 2003-07-18 2005-01-19 Aventis Pharma Deutschland GmbH Utilisation d'inhibiteur de pak pour le traitement d'une maladie articulaire
ZA200604036B (en) * 2003-10-23 2007-09-26 Cipla Ltd Transdermal pharmaceutical spray formulations comprising a VP/VA copolymer and a non-aqueous vehicle
EP1531333A1 (fr) 2003-11-12 2005-05-18 Aventis Pharma Deutschland GmbH Méthode pour la identification d' une risque des troubles thrombogénique par détermination du polymorphisme TAFI-ILE347
JP2008501638A (ja) 2004-04-23 2008-01-24 ドイツ連邦共和国 ＩＣＯＳ陽性細胞のｉｎｖｉｖｏ枯渇によるＴ細胞介在病態の治療方法
US20060127463A1 (en) * 2004-12-15 2006-06-15 Nugara Peter N Composite structure including a low vinyl acetate layer
BRPI0609209A2 (pt) 2005-03-11 2010-03-02 Sanofi Aventis uso de mgc4504
DE102005048898A1 (de) 2005-10-12 2007-04-19 Sanofi-Aventis Deutschland Gmbh EGLN2-Varianten und ihre Verwendung bei der Vorbeugung oder Behandlung thromboembolischer Erkrankungen und koronarer Herzerkrankungen
EP1795609A1 (fr) 2005-12-06 2007-06-13 Sanofi-Aventis Deutschland GmbH Méthode de diagnostique et de traitement des maladies cardiovasculaires
EP2105742A1 (fr) 2008-03-26 2009-09-30 Sanofi-Aventis Utilisation de cathepsine C
US8741949B2 (en) 2008-06-27 2014-06-03 Meta-Iq Aps Inhibitors of carnitin-palmitoyl-tranferase-1 for the treatment and prevention of disorders caused by delipidation of neural tissue
EP2293072A1 (fr) 2009-08-31 2011-03-09 Sanofi-Aventis Utilisation de la cathepsine H
TW201241179A (en) 2010-12-17 2012-10-16 Sanofi Sa MiRNAs in joint disease
TW201238973A (en) 2010-12-17 2012-10-01 Sanofi Sa MiRNAs in joint disease
TW201238974A (en) 2010-12-17 2012-10-01 Sanofi Sa MiRNAs in joint disease
TW201239097A (en) 2010-12-17 2012-10-01 Sanofi Sa MiRNAs in joint disease
WO2013067346A1 (fr) * 2011-11-04 2013-05-10 Agile Therapeutics, Inc. Méthodes et composition d'administration dermique
ES2885523T3 (es) 2011-11-23 2021-12-14 Therapeuticsmd Inc Formulaciones y terapias de reposición hormonal de combinación naturales
US9301920B2 (en) 2012-06-18 2016-04-05 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
US10806697B2 (en) 2012-12-21 2020-10-20 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10806740B2 (en) 2012-06-18 2020-10-20 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
US20150196640A1 (en) 2012-06-18 2015-07-16 Therapeuticsmd, Inc. Progesterone formulations having a desirable pk profile
US20130338122A1 (en) 2012-06-18 2013-12-19 Therapeuticsmd, Inc. Transdermal hormone replacement therapies
US10471072B2 (en) 2012-12-21 2019-11-12 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US11266661B2 (en) 2012-12-21 2022-03-08 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US11246875B2 (en) 2012-12-21 2022-02-15 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10568891B2 (en) 2012-12-21 2020-02-25 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US9180091B2 (en) 2012-12-21 2015-11-10 Therapeuticsmd, Inc. Soluble estradiol capsule for vaginal insertion
US10537581B2 (en) 2012-12-21 2020-01-21 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US8877868B2 (en) * 2013-02-26 2014-11-04 Henkel IP & Holding GmbH Hot melt adhesive comprising cyanoacrylate curing compounds
JP2017516768A (ja) 2014-05-22 2017-06-22 セラピューティックスエムディー インコーポレーテッドＴｈｅｒａｐｅｕｔｉｃｓｍｄ， Ｉｎｃ． 天然の併用ホルモン補充療法剤及び療法
US10328087B2 (en) 2015-07-23 2019-06-25 Therapeuticsmd, Inc. Formulations for solubilizing hormones
BR112018070199A2 (pt) 2016-04-01 2019-01-29 Therapeuticsmd Inc composição farmacêutica de hormônio esteroide
WO2017173044A1 (fr) 2016-04-01 2017-10-05 Therapeuticsmd Inc. Compositions d'hormones stéroïdes dans des huiles à chaîne moyenne
US11633405B2 (en) 2020-02-07 2023-04-25 Therapeuticsmd, Inc. Steroid hormone pharmaceutical formulations

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US4655768A (en) * 1984-07-06 1987-04-07 Avery International Corporation Bandage for sustained delivery of drugs
JP2572763B2 (ja) * 1987-04-02 1997-01-16 帝國製薬株式会社 エトフェナマ−ト含有貼付薬
US5273757A (en) * 1987-09-01 1993-12-28 Lts Lohmann Therapie-Systeme Gmbh & Co. Kg Apparatus for the delivery of substances, processes for the production thereof and use thereof
DE3743947A1 (de) * 1987-09-01 1989-03-09 Lohmann Gmbh & Co Kg Vorrichtung zur gesteuerten abgabe von nicotin, verfahren zu ihrer herstellung sowie ihre verwendung
US5656286A (en) * 1988-03-04 1997-08-12 Noven Pharmaceuticals, Inc. Solubility parameter based drug delivery system and method for altering drug saturation concentration
DE4002281A1 (de) * 1990-01-26 1991-08-01 Lohmann Therapie Syst Lts Transdermales therapeutisches system mit dem wirkstoff tulobuterol
JP2849937B2 (ja) * 1990-04-18 1999-01-27 日東電工株式会社 医療用貼付剤
DE69108512T2 (de) * 1990-05-17 1995-08-03 Hisamitsu Pharmaceutical Co Estradiol enthaltende transdermale zubereitung.
JP3523275B2 (ja) * 1992-03-26 2004-04-26 東光薬品工業株式会社 貼付剤
FR2717689B1 (fr) * 1994-03-28 1996-07-05 Lhd Lab Hygiene Dietetique Système matriciel transdermique d'administration d'un oestrogène et/ou un progestatif à base de copolymère styrène-isoprène-styrène.

Also Published As

Publication number Publication date
JPH11514989A (ja) 1999-12-21
AU7135196A (en) 1997-04-17
CN1197389A (zh) 1998-10-28
NO981315L (no) 1998-03-24
WO1997011689A1 (fr) 1997-04-03
CA2233171A1 (fr) 1997-04-03
US6007835A (en) 1999-12-28
FR2739031A1 (fr) 1997-03-28
NO981315D0 (no) 1998-03-23
EP0852493A1 (fr) 1998-07-15

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