DK2919796T3 - Brug af akkermansia til behandling af stofskiftesygdomme - Google Patents
Brug af akkermansia til behandling af stofskiftesygdomme Download PDFInfo
- Publication number
- DK2919796T3 DK2919796T3 DK13792006.2T DK13792006T DK2919796T3 DK 2919796 T3 DK2919796 T3 DK 2919796T3 DK 13792006 T DK13792006 T DK 13792006T DK 2919796 T3 DK2919796 T3 DK 2919796T3
- Authority
- DK
- Denmark
- Prior art keywords
- metable
- akkermansia
- diseases
- treatment
- metable diseases
- Prior art date
Links
- 0 C*(*)(*)CC1*CC(*)C1 Chemical compound C*(*)(*)CC1*CC(*)C1 0.000 description 1
- JKKHRLLTWYVLJP-UHFFFAOYSA-N COCC(C(CN=O)N)OC Chemical compound COCC(C(CN=O)N)OC JKKHRLLTWYVLJP-UHFFFAOYSA-N 0.000 description 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/74—Bacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/74—Bacteria
- A61K35/741—Probiotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Diabetes (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Molecular Biology (AREA)
- Pulmonology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Child & Adolescent Psychology (AREA)
- Rheumatology (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Endocrinology (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Emergency Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Pain & Pain Management (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/EP2012/073011 WO2014075745A1 (en) | 2012-11-19 | 2012-11-19 | Use of akkermansia for treating metabolic disorders |
| PCT/EP2013/073972 WO2014076246A1 (en) | 2012-11-19 | 2013-11-15 | Use of akkermansia for treating metabolic disorders |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK2919796T3 true DK2919796T3 (da) | 2021-05-31 |
Family
ID=47257788
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK13792006.2T DK2919796T3 (da) | 2012-11-19 | 2013-11-15 | Brug af akkermansia til behandling af stofskiftesygdomme |
Country Status (14)
| Country | Link |
|---|---|
| US (10) | US20150306152A1 (da) |
| JP (2) | JP6426616B2 (da) |
| KR (7) | KR20210111871A (da) |
| CN (2) | CN111603488B (da) |
| AU (1) | AU2013346726B2 (da) |
| BR (1) | BR112015011403A2 (da) |
| CA (1) | CA2891758C (da) |
| DK (1) | DK2919796T3 (da) |
| EA (2) | EA202100040A3 (da) |
| ES (3) | ES3037446T3 (da) |
| MX (1) | MX365835B (da) |
| PL (1) | PL3862010T3 (da) |
| PT (1) | PT2919796T (da) |
| WO (2) | WO2014075745A1 (da) |
Families Citing this family (110)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB201112091D0 (en) | 2011-07-14 | 2011-08-31 | Gt Biolog Ltd | Bacterial strains isolated from pigs |
| GB201117313D0 (en) | 2011-10-07 | 2011-11-16 | Gt Biolog Ltd | Bacterium for use in medicine |
| US9173910B2 (en) | 2012-02-29 | 2015-11-03 | The General Hospital Corporation | Compositions of microbiota and methods related thereto |
| WO2013139861A1 (en) | 2012-03-20 | 2013-09-26 | Luc Montagnier | Methods and pharmaceutical compositions of the treatment of autistic syndrome disorders |
| WO2014075745A1 (en) * | 2012-11-19 | 2014-05-22 | Université Catholique de Louvain | Use of akkermansia for treating metabolic disorders |
| GB201306536D0 (en) | 2013-04-10 | 2013-05-22 | Gt Biolog Ltd | Polypeptide and immune modulation |
| US10633714B2 (en) | 2013-07-21 | 2020-04-28 | Pendulum Therapeutics, Inc. | Methods and systems for microbiome characterization, monitoring and treatment |
| US20150246081A1 (en) * | 2014-03-03 | 2015-09-03 | Shayne Kenneth Morris | Probiotics with methods for growth and use separately and in combination |
| KR101740893B1 (ko) | 2014-05-20 | 2017-06-13 | 주식회사 엠디헬스케어 | Akkermansia muciniphila 균에서 유래하는 세포밖 소포를 유효성분으로 함유하는 대사질환의 치료 또는 예방용 조성물 |
| CN113730442A (zh) * | 2014-10-31 | 2021-12-03 | 潘德勒姆治疗公司 | 与病症的微生物治疗和诊断有关的方法和组合物 |
| SMT201800291T1 (it) | 2014-12-23 | 2018-07-17 | 4D Pharma Res Limited | Polipeptide pirina e modulazione immunitaria |
| SG10201913609PA (en) | 2014-12-23 | 2020-03-30 | 4D Pharma Res Ltd | Immune modulation |
| EP3292134B1 (en) | 2015-05-06 | 2020-10-21 | Wageningen Universiteit | Method of culturing akkermansia |
| EA201700507A1 (ru) | 2015-05-06 | 2018-05-31 | Университе Католик Де Лувен | Композиция, клетки, способы получения полипептида, применение полипептида и клеток, способ лечения |
| MA41010B1 (fr) | 2015-06-15 | 2020-01-31 | 4D Pharma Res Ltd | Compositions comprenant des souches bactériennes |
| RS59446B1 (sr) | 2015-06-15 | 2019-11-29 | 4D Pharma Res Ltd | Blautia stercosis i wexlerae za upotrebu u lečenju inflamatornih i autoimunskih bolesti |
| SMT201900539T1 (it) | 2015-06-15 | 2019-11-13 | 4D Pharma Res Limited | Composizioni comprendenti ceppi batterici |
| MA41060B1 (fr) | 2015-06-15 | 2019-11-29 | 4D Pharma Res Ltd | Compositions comprenant des souches bactériennes |
| EP3360559B1 (en) | 2015-06-15 | 2019-10-23 | 4D Pharma Research Limited | Compositions comprising bacterial strains |
| CN105106245A (zh) * | 2015-08-24 | 2015-12-02 | 上海交通大学医学院附属瑞金医院 | Akkermansia muciniphila BAA-835菌株的应用 |
| CN105030841A (zh) * | 2015-08-24 | 2015-11-11 | 上海交通大学医学院附属瑞金医院 | Akkermansia muciniphila BAA-835菌株的应用 |
| CN108289918B (zh) * | 2015-09-10 | 2022-01-18 | 卢万天主教大学 | 经巴氏灭菌的艾克曼菌用于治疗代谢病症的用途 |
| JP2018534277A (ja) | 2015-10-05 | 2018-11-22 | シュヴァイツェリッシェ フォルシュングスインスティテュート フュア ホーフゲブリクスクリーマ ウント メディツィン イン ダヴォス | 炎症性状態を治療するためのアッカーマンシア・ムシニフィラ(Akkermansia muciniphila)の使用 |
| WO2017060491A1 (en) * | 2015-10-09 | 2017-04-13 | Biogaia Ab | Mucus thickness to prevent diseases |
| CN105176822B (zh) * | 2015-10-23 | 2019-01-11 | 广州康泽医疗科技有限公司 | 一种人类肠道益生菌的优化分离方法 |
| CA3005781C (en) | 2015-11-20 | 2019-01-22 | 4D Pharma Research Limited | Compositions comprising bacterial strains |
| GB201520497D0 (en) | 2015-11-20 | 2016-01-06 | 4D Pharma Res Ltd | Compositions comprising bacterial strains |
| GB201520631D0 (en) | 2015-11-23 | 2016-01-06 | 4D Pharma Res Ltd | Compositions comprising bacterial strains |
| GB201520638D0 (en) | 2015-11-23 | 2016-01-06 | 4D Pharma Res Ltd | Compositions comprising bacterial strains |
| CN116570631A (zh) | 2016-02-04 | 2023-08-11 | 根特大学 | 微生物群落用于人类和动物健康的用途 |
| CA3016179C (en) | 2016-03-04 | 2019-08-13 | 4D Pharma Plc | Compositions comprising bacterial blautia strains for treating visceral hypersensitivity |
| GB201612191D0 (en) | 2016-07-13 | 2016-08-24 | 4D Pharma Plc | Compositions comprising bacterial strains |
| AU2017228502C1 (en) * | 2016-03-04 | 2021-09-16 | The Regents Of The University Of California | Microbial consortium and uses thereof |
| DK3443071T3 (da) | 2016-04-11 | 2022-01-31 | Univ Wageningen | Hidtil ukendt bakterieart |
| GB201609811D0 (en) | 2016-06-05 | 2016-07-20 | Snipr Technologies Ltd | Methods, cells, systems, arrays, RNA and kits |
| EP3483256A4 (en) * | 2016-07-11 | 2019-12-04 | Korea Research Institute of Bioscience and Biotechnology | AKKERMANSIA MUCINIPHILA TRIBE WITH EFFECT FOR PREVENTING OR TREATING DEGENERATIVE BRAIN DISEASES OR METABOLIC DISEASES AND USE THEREOF |
| TWI802545B (zh) | 2016-07-13 | 2023-05-21 | 英商4D製藥有限公司 | 包含細菌菌株之組合物 |
| CN109874329B (zh) * | 2016-08-12 | 2023-08-29 | 深圳华大生命科学研究院 | 一种产丁酸栖粪杆菌及其培养方法和应用 |
| GB201621123D0 (en) | 2016-12-12 | 2017-01-25 | 4D Pharma Plc | Compositions comprising bacterial strains |
| EP3558329B1 (en) * | 2016-12-20 | 2024-01-31 | The Regents of The University of California | Compositions and methods for inhibiting seizures |
| EP3606325B1 (en) | 2017-04-03 | 2024-09-04 | Gusto Global, LLC | Rational design of microbial-based biotherapeutics |
| FR3065643B1 (fr) | 2017-04-26 | 2020-04-17 | Usines Chimiques D'ivry La Bataille (Ucib) | Composition nutraceutique et/ou pharmaceutique pour stimuler la production de beta-defensines de type 2 |
| US10695386B2 (en) | 2017-05-11 | 2020-06-30 | Shayne K. Morris | Skin microbiome colonizer formulations and methods for use |
| TW201907929A (zh) | 2017-05-22 | 2019-03-01 | 英商4D製藥研究有限公司 | 包含細菌品系之組成物 |
| TW201907931A (zh) | 2017-05-24 | 2019-03-01 | 英商4D製藥研究有限公司 | 包含細菌菌株之組合物 |
| LT3638271T (lt) | 2017-06-14 | 2021-01-11 | 4D Pharma Research Limited | Kompozicijos, apimančios bakterines padermes |
| PL3600363T3 (pl) | 2017-06-14 | 2021-06-14 | 4D Pharma Research Limited | Kompozycje zawierające szczepy bakteryjne |
| WO2018229236A2 (en) | 2017-06-14 | 2018-12-20 | 4D Pharma Research Limited | Compositions comprising bacterial strains |
| TWI640314B (zh) * | 2017-08-22 | 2018-11-11 | 長庚生物科技股份有限公司 | 戈氏副擬桿菌用於降低胰島素抗性及提升葡萄糖耐受性之用途 |
| TWI636788B (zh) * | 2017-08-28 | 2018-10-01 | 長庚生物科技股份有限公司 | 戈氏副擬桿菌用於抑制脂肪肝疾病之用途 |
| WO2019046646A1 (en) | 2017-08-30 | 2019-03-07 | Whole Biome Inc. | METHODS AND COMPOSITIONS FOR THE TREATMENT OF MICROBIOMA ASSOCIATED DISORDERS |
| JP7171602B2 (ja) * | 2017-11-08 | 2022-11-15 | アサヒグループホールディングス株式会社 | アッカーマンシア・ムシニフィラ増殖材 |
| EP3716983A4 (en) * | 2017-11-30 | 2022-03-02 | Glycom A/S | HUMAN MILK OLIGOSACCHARIDES AND SYNTHETIC COMPOSITIONS THEREOF FOR MICROBIOTA MODULATION |
| US11534465B2 (en) * | 2018-03-02 | 2022-12-27 | Academisch Medisch Centrum | Fecal matter for treatment of autoimmune diseases |
| WO2019199895A1 (en) | 2018-04-10 | 2019-10-17 | Siolta Therapeutics, Inc. | Microbial consortia |
| US11168299B2 (en) | 2018-04-11 | 2021-11-09 | Shayne Morris | Pairing probiotics and prebiotics, methods for growth and use, separately and in combination |
| US11291696B2 (en) | 2018-04-11 | 2022-04-05 | Shayne Morris | Pairing probiotics and prebiotics, methods for growth and use, separately and in combination |
| KR102225939B1 (ko) * | 2018-04-19 | 2021-03-10 | 주식회사 고바이오랩 | 신규한 Bacteroides vulgatus 균주 및 이를 유효 성분으로 하는 면역 및 대사성 질환 예방 또는 치료용 조성물 |
| EP3802788B1 (en) | 2018-05-15 | 2025-07-02 | Duke University | Systems and methods for genetic manipulation of akkermansia species |
| CN110496140B (zh) * | 2018-05-18 | 2022-05-31 | 瑞微(深圳)生物科技有限公司 | 脆弱拟杆菌或阿克曼粘细菌在制备用于预防或治疗肿瘤的药物中的应用 |
| US12292445B2 (en) | 2018-05-23 | 2025-05-06 | The Regents Of The University Of California | Methods of selecting subjects for treatment with metabolomic modulators |
| EP3594321A1 (en) * | 2018-07-10 | 2020-01-15 | Université catholique de Louvain | Dusodibacter, a novel bacterial genus of the gastroinstestinal microbiota and uses thereof |
| EP3823651A4 (en) | 2018-07-19 | 2022-04-27 | Pendulum Therapeutics, Inc. | METHODS AND COMPOSITIONS FOR MICROBIAL TRANSPLANTATION |
| CA3109264A1 (en) * | 2018-08-20 | 2020-02-27 | Murdoch Children's Research Institute | Behavioural treatment |
| CN110964650B (zh) * | 2018-09-27 | 2022-10-11 | 上海上药信谊药厂有限公司 | 一种用于预防和治疗代谢疾病的菌株及其应用 |
| KR102377407B1 (ko) * | 2018-10-01 | 2022-03-22 | 한국생명공학연구원 | 아커만시아 뮤시니필라 균주 또는 이의 배양물을 유효성분으로 함유하는 노화방지용 조성물 |
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| WO2008076696A2 (en) | 2006-12-18 | 2008-06-26 | Washington University In St. Louis | The gut microbiome as a biomarker and therapeutic target for treating obesity or an obesity related disorder |
| EP2030623A1 (en) | 2007-08-17 | 2009-03-04 | Nestec S.A. | Preventing and/or treating metabolic disorders by modulating the amount of enterobacteria |
| EP2103226A1 (en) * | 2008-03-18 | 2009-09-23 | Friesland Brands B.V. | Long-life probiotic food product |
| NZ602704A (en) | 2010-03-01 | 2015-01-30 | Agronomique Inst Nat Rech | Method of diagnostic of inflammatory bowel diseases |
| US9173910B2 (en) * | 2012-02-29 | 2015-11-03 | The General Hospital Corporation | Compositions of microbiota and methods related thereto |
| WO2014075745A1 (en) * | 2012-11-19 | 2014-05-22 | Université Catholique de Louvain | Use of akkermansia for treating metabolic disorders |
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