DK1656360T3 - Thiazolinderivater som selektive androgenreceptor-modulatorer - Google Patents
Thiazolinderivater som selektive androgenreceptor-modulatorerInfo
- Publication number
- DK1656360T3 DK1656360T3 DK04755044T DK04755044T DK1656360T3 DK 1656360 T3 DK1656360 T3 DK 1656360T3 DK 04755044 T DK04755044 T DK 04755044T DK 04755044 T DK04755044 T DK 04755044T DK 1656360 T3 DK1656360 T3 DK 1656360T3
- Authority
- DK
- Denmark
- Prior art keywords
- androgen receptor
- receptor modulators
- selective androgen
- thiazoline derivatives
- derivatives
- Prior art date
Links
- 150000003549 thiazolines Chemical class 0.000 title abstract 2
- 239000000849 selective androgen receptor modulator Substances 0.000 title 1
- 102000001307 androgen receptors Human genes 0.000 abstract 1
- 108010080146 androgen receptors Proteins 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 208000035475 disorder Diseases 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/08—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D277/12—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/14—Drugs for dermatological disorders for baldness or alopecia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/26—Androgens
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Endocrinology (AREA)
- Dermatology (AREA)
- Reproductive Health (AREA)
- Virology (AREA)
- Pregnancy & Childbirth (AREA)
- Tropical Medicine & Parasitology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Urology & Nephrology (AREA)
- Gynecology & Obstetrics (AREA)
- Molecular Biology (AREA)
- AIDS & HIV (AREA)
- Nutrition Science (AREA)
- Diabetes (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Thiazole And Isothizaole Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US47871203P | 2003-06-13 | 2003-06-13 | |
| PCT/US2004/018665 WO2004113309A1 (en) | 2003-06-13 | 2004-06-12 | Thiazoline derivatives as selective androgen receptor modulators (sarms) |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1656360T3 true DK1656360T3 (da) | 2007-12-27 |
Family
ID=33539114
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK04755044T DK1656360T3 (da) | 2003-06-13 | 2004-06-12 | Thiazolinderivater som selektive androgenreceptor-modulatorer |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US20050014952A1 (da) |
| EP (1) | EP1656360B1 (da) |
| JP (1) | JP4898446B2 (da) |
| CN (1) | CN1835937B (da) |
| AT (1) | ATE370133T1 (da) |
| AU (1) | AU2004249697B2 (da) |
| CA (1) | CA2528764A1 (da) |
| CY (1) | CY1106973T1 (da) |
| DE (1) | DE602004008300T2 (da) |
| DK (1) | DK1656360T3 (da) |
| ES (1) | ES2291906T3 (da) |
| PL (1) | PL1656360T3 (da) |
| PT (1) | PT1656360E (da) |
| WO (1) | WO2004113309A1 (da) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7465809B2 (en) * | 2004-11-16 | 2008-12-16 | Janssen Pharmaceutica N.V. | Heterocycle derivatives useful as selective androgen receptor modulators (SARMs) |
| US7709516B2 (en) | 2005-06-17 | 2010-05-04 | Endorecherche, Inc. | Helix 12 directed non-steroidal antiandrogens |
| US9284345B2 (en) | 2007-04-12 | 2016-03-15 | Endorecherche, Inc. | 17alpha-substituted steroids as systemic antiandrogens and selective androgen receptor modulators |
| CA2861066C (en) * | 2012-01-12 | 2024-01-02 | Yale University | Compounds and methods for the enhanced degradation of targeted proteins and other polypeptides by an e3 ubiquitin ligase |
| CN103450112B (zh) * | 2013-08-07 | 2019-09-13 | 华东理工大学 | 一种n-桥连接的含氮五元杂环化合物及其制备与用途 |
| US9682960B2 (en) | 2013-12-19 | 2017-06-20 | Endorecherche, Inc. | Non-steroidal antiandrogens and selective androgen receptor modulators with a pyridyl moiety |
| SG11202111402PA (en) | 2019-05-14 | 2021-11-29 | Nuvation Bio Inc | Anti-cancer nuclear hormone receptor-targeting compounds |
| US11952349B2 (en) | 2019-11-13 | 2024-04-09 | Nuvation Bio Inc. | Anti-cancer nuclear hormone receptor-targeting compounds |
| KR20230160299A (ko) | 2021-03-23 | 2023-11-23 | 누베이션 바이오 인크. | 항암 핵 호르몬 수용체 표적화 화합물 |
| WO2022235585A1 (en) | 2021-05-03 | 2022-11-10 | Nuvation Bio Inc. | Anti-cancer nuclear hormone receptor-targeting compounds |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU1676595A (en) * | 1994-01-24 | 1995-08-08 | E.I. Du Pont De Nemours And Company | Arthropodicidal 2-oxa and thia-zolines |
| US6403623B1 (en) * | 1999-05-27 | 2002-06-11 | Unuversity Of Notre Dame Du Lac | Heterocyclic antituberculosis agents |
| ATE423092T1 (de) * | 2000-08-24 | 2009-03-15 | Univ Tennessee Res Foundation | Selektive modulatoren des androgenrezeptors und methoden zu deren verwendung |
-
2004
- 2004-06-12 CN CN2004800230915A patent/CN1835937B/zh not_active Expired - Fee Related
- 2004-06-12 JP JP2006533745A patent/JP4898446B2/ja not_active Expired - Fee Related
- 2004-06-12 PT PT04755044T patent/PT1656360E/pt unknown
- 2004-06-12 DK DK04755044T patent/DK1656360T3/da active
- 2004-06-12 PL PL04755044T patent/PL1656360T3/pl unknown
- 2004-06-12 WO PCT/US2004/018665 patent/WO2004113309A1/en active IP Right Grant
- 2004-06-12 EP EP04755044A patent/EP1656360B1/en not_active Expired - Lifetime
- 2004-06-12 AU AU2004249697A patent/AU2004249697B2/en not_active Ceased
- 2004-06-12 DE DE602004008300T patent/DE602004008300T2/de not_active Expired - Lifetime
- 2004-06-12 AT AT04755044T patent/ATE370133T1/de active
- 2004-06-12 US US10/866,591 patent/US20050014952A1/en not_active Abandoned
- 2004-06-12 CA CA002528764A patent/CA2528764A1/en not_active Abandoned
- 2004-06-12 ES ES04755044T patent/ES2291906T3/es not_active Expired - Lifetime
-
2007
- 2007-11-05 CY CY20071101413T patent/CY1106973T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CN1835937A (zh) | 2006-09-20 |
| CN1835937B (zh) | 2012-07-18 |
| JP2007501287A (ja) | 2007-01-25 |
| PT1656360E (pt) | 2007-10-22 |
| CY1106973T1 (el) | 2012-09-26 |
| EP1656360A1 (en) | 2006-05-17 |
| DE602004008300D1 (de) | 2007-09-27 |
| AU2004249697B2 (en) | 2010-04-22 |
| DE602004008300T2 (de) | 2008-05-08 |
| WO2004113309A1 (en) | 2004-12-29 |
| US20050014952A1 (en) | 2005-01-20 |
| ATE370133T1 (de) | 2007-09-15 |
| JP4898446B2 (ja) | 2012-03-14 |
| ES2291906T3 (es) | 2008-03-01 |
| EP1656360B1 (en) | 2007-08-15 |
| AU2004249697A1 (en) | 2004-12-29 |
| PL1656360T3 (pl) | 2008-01-31 |
| CA2528764A1 (en) | 2004-12-29 |
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