DK1558600T3 - Udvalgte CGRP-antagonister, fremgangsmåder til fremstilling deraf samt deres anvendelse som lægemiddel - Google Patents

Udvalgte CGRP-antagonister, fremgangsmåder til fremstilling deraf samt deres anvendelse som lægemiddel

Info

Publication number: DK1558600T3
Authority: DK; Denmark
Prior art keywords: drug; preparation; methods; cgrp antagonists; selected cgrp
Prior art date: 2002-10-25

Application number

DK03809317T

Other languages

Danish (da)

English (en)

Inventor

Klaus Rudolf

Stephan Georg Mueller

Dirk Stenkamp

Philipp Lustenberger

Eckhart Bauer

Arndt Kirsten

Henri Doods

Alexander Dreyer

Marcus Schindler

Original Assignee

Boehringer Ingelheim Pharma

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-10-25

Filing date

2003-10-23

Publication date

2008-09-01

2003-10-23 Application filed by Boehringer Ingelheim Pharma filed Critical Boehringer Ingelheim Pharma

2008-09-01 Application granted granted Critical

2008-09-01 Publication of DK1558600T3 publication Critical patent/DK1558600T3/da

Links

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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/12—Antidiarrhoeals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/14—Decongestants or antiallergics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
- C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
- C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
- C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
- C07D453/04—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems having a quinolyl-4, a substituted quinolyl-4 or a alkylenedioxy-quinolyl-4 radical linked through only one carbon atom, attached in position 2, e.g. quinine
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/10—Spiro-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/08—Bridged systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems

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Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Medicinal Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Pulmonology (AREA)
Diabetes (AREA)
Pain & Pain Management (AREA)
Endocrinology (AREA)
Rheumatology (AREA)
Dermatology (AREA)
Psychiatry (AREA)
Obesity (AREA)
Oncology (AREA)
Addiction (AREA)
Cardiology (AREA)
Communicable Diseases (AREA)
Emergency Medicine (AREA)
Heart & Thoracic Surgery (AREA)
Hematology (AREA)
Otolaryngology (AREA)
Ophthalmology & Optometry (AREA)
Immunology (AREA)
Orthopedic Medicine & Surgery (AREA)
Physical Education & Sports Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

DK03809317T 2002-10-25 2003-10-23 Udvalgte CGRP-antagonister, fremgangsmåder til fremstilling deraf samt deres anvendelse som lægemiddel DK1558600T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DE10250080A DE10250080A1 (de)	2002-10-25	2002-10-25	Ausgewählte CGRP-Antagonisten, Verfahren zu deren Herstellung sowie deren Verwendung als Arzneimittel
PCT/EP2003/011762 WO2004037810A1 (de)	2002-10-25	2003-10-23	Ausgewählte cgrp-antagonisten, verfahren zu deren herstellung sowie deren verwendung als arzneimittel

Publications (1)

Publication Number	Publication Date
DK1558600T3 true DK1558600T3 (da)	2008-09-01

Family

ID=32103086

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK03809317T DK1558600T3 (da)	2002-10-25	2003-10-23	Udvalgte CGRP-antagonister, fremgangsmåder til fremstilling deraf samt deres anvendelse som lægemiddel

Country Status (27)

Country	Link
EP (1)	EP1558600B1 (es)
JP (1)	JP4401296B2 (es)
KR (1)	KR20050074970A (es)
CN (1)	CN1708493A (es)
AR (1)	AR041718A1 (es)
AT (1)	ATE394392T1 (es)
AU (1)	AU2003276156A1 (es)
BR (1)	BR0315665A (es)
CA (1)	CA2503455A1 (es)
CO (1)	CO5570704A2 (es)
DE (2)	DE10250080A1 (es)
DK (1)	DK1558600T3 (es)
EA (1)	EA009219B1 (es)
EC (1)	ECSP055747A (es)
ES (1)	ES2306918T3 (es)
HR (1)	HRP20050364A2 (es)
IL (1)	IL168056A0 (es)
MX (1)	MXPA05004375A (es)
NO (1)	NO20052496L (es)
PE (1)	PE20040592A1 (es)
PL (1)	PL376450A1 (es)
RS (1)	RS20050311A (es)
TW (1)	TW200413317A (es)
UA (1)	UA79323C2 (es)
UY (1)	UY28034A1 (es)
WO (1)	WO2004037810A1 (es)
ZA (1)	ZA200502248B (es)

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DE102004063752A1 (de) *	2004-12-29	2006-07-13	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Verwendung ausgewählter CGRP-Antagonisten zur Bekämpfung menopausaler Hitzewallungen
US7491717B2 (en)	2005-03-23	2009-02-17	Boehringer Ingelheim International Gmbh	Selected CGRP-antagonists, process for preparing them and their use as pharmaceutical compositions
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EP1770091A1 (de) *	2005-09-29	2007-04-04	Boehringer Ingelheim Pharma GmbH & Co. KG	CGRP-Antagonisten, Verfahren zu deren Herstellung sowie deren Verwendung als Arzneimittel
US7439237B2 (en)	2005-04-15	2008-10-21	Boehringer Ingelheim International Gmbh	Selected CGRP-antagonists, process for preparing them and their use as pharmaceutical compositions
DE102005038831A1 (de) *	2005-08-17	2007-02-22	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Ausgewählte CGRP-Antagonisten, Verfahren zu deren Herstellung sowie deren Verwendung als Arzneimittel
US7834007B2 (en)	2005-08-25	2010-11-16	Bristol-Myers Squibb Company	CGRP antagonists
EP1770087A1 (de) *	2005-09-29	2007-04-04	Boehringer Ingelheim Pharma GmbH & Co. KG	Ausgewählte CGRP-Antagonisten, Verfahren zu deren Herstellung sowie deren Verwendung als Arzneimittel
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DE102006017827A1 (de)	2006-04-13	2007-10-18	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Neue kristalline Verbindungen
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DE102007038250A1 (de)	2007-08-13	2009-02-19	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Neues Herstellverfahren
EP2065381A1 (de)	2007-10-18	2009-06-03	Boehringer Ingelheim Pharma GmbH & Co. KG	CGRP Antagonisten
JP5366960B2 (ja)	2007-10-18	2013-12-11	ベーリンガーインゲルハイムインターナショナルゲゼルシャフトミットベシュレンクテルハフツング	Ｃｇｒｐアンタゴニスト
EP2251338A3 (de)	2007-11-22	2011-06-08	Boehringer Ingelheim International GmbH	Organische Verbindungen
KR101409076B1 (ko)	2008-08-01	2014-06-18	미쓰이가가쿠 아그로 가부시키가이샤	아미드 유도체, 그 아미드 유도체를 함유하는 유해 생물 방제제 및 유해 생물의 방제 방법
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WO2000018764A1 (en) *	1998-09-30	2000-04-06	Merck Sharp & Dohme Limited	Benzimidazolinyl piperidines as cgrp ligands
DE19937304C2 (de) *	1999-08-10	2003-08-21	Boehringer Ingelheim Pharma	Verwendung von CGRP-Antagonisten zur Bekämpfung menopausaler Hitzewallungen

2002
- 2002-10-25 DE DE10250080A patent/DE10250080A1/de not_active Withdrawn
2003
- 2003-10-22 UY UY28034A patent/UY28034A1/es not_active Application Discontinuation
- 2003-10-23 AT AT03809317T patent/ATE394392T1/de active
- 2003-10-23 CA CA002503455A patent/CA2503455A1/en not_active Abandoned
- 2003-10-23 PE PE2003001077A patent/PE20040592A1/es not_active Application Discontinuation
- 2003-10-23 RS YUP-2005/0311A patent/RS20050311A/sr unknown
- 2003-10-23 AU AU2003276156A patent/AU2003276156A1/en not_active Abandoned
- 2003-10-23 WO PCT/EP2003/011762 patent/WO2004037810A1/de active IP Right Grant
- 2003-10-23 MX MXPA05004375A patent/MXPA05004375A/es not_active Application Discontinuation
- 2003-10-23 EP EP03809317A patent/EP1558600B1/de not_active Expired - Lifetime
- 2003-10-23 UA UAA200504872A patent/UA79323C2/uk unknown
- 2003-10-23 KR KR1020057007144A patent/KR20050074970A/ko not_active Withdrawn
- 2003-10-23 BR BR0315665-6A patent/BR0315665A/pt not_active IP Right Cessation
- 2003-10-23 EA EA200500600A patent/EA009219B1/ru not_active IP Right Cessation
- 2003-10-23 HR HR20050364A patent/HRP20050364A2/hr not_active Application Discontinuation
- 2003-10-23 DK DK03809317T patent/DK1558600T3/da active
- 2003-10-23 CN CNA2003801020040A patent/CN1708493A/zh active Pending
- 2003-10-23 JP JP2004545963A patent/JP4401296B2/ja not_active Expired - Fee Related
- 2003-10-23 DE DE50309807T patent/DE50309807D1/de not_active Expired - Lifetime
- 2003-10-23 ES ES03809317T patent/ES2306918T3/es not_active Expired - Lifetime
- 2003-10-23 PL PL03376450A patent/PL376450A1/xx not_active Application Discontinuation
- 2003-10-24 AR ARP030103889A patent/AR041718A1/es unknown
- 2003-10-24 TW TW092129640A patent/TW200413317A/zh unknown
2005
- 2005-03-17 ZA ZA200502248A patent/ZA200502248B/en unknown
- 2005-04-14 IL IL168056A patent/IL168056A0/en unknown
- 2005-04-25 EC EC2005005747A patent/ECSP055747A/es unknown
- 2005-05-24 NO NO20052496A patent/NO20052496L/no not_active Application Discontinuation
- 2005-05-24 CO CO05050511A patent/CO5570704A2/es not_active Application Discontinuation

Also Published As

Publication number	Publication date
JP2006516244A (ja)	2006-06-29
CO5570704A2 (es)	2005-10-31
CA2503455A1 (en)	2004-05-06
EA009219B1 (ru)	2007-12-28
ES2306918T3 (es)	2008-11-16
AR041718A1 (es)	2005-05-26
MXPA05004375A (es)	2005-07-05
UY28034A1 (es)	2004-05-31
AU2003276156A1 (en)	2004-05-13
EP1558600A1 (de)	2005-08-03
NO20052496L (no)	2005-06-24
HRP20050364A2 (en)	2006-05-31
KR20050074970A (ko)	2005-07-19
EP1558600B1 (de)	2008-05-07
WO2004037810A1 (de)	2004-05-06
TW200413317A (en)	2004-08-01
BR0315665A (pt)	2005-08-30
EA200500600A1 (ru)	2006-02-24
RS20050311A (sr)	2007-08-03
DE50309807D1 (de)	2008-06-19
IL168056A0 (en)	2009-02-11
UA79323C2 (en)	2007-06-11
ATE394392T1 (de)	2008-05-15
ZA200502248B (en)	2006-08-30
DE10250080A1 (de)	2004-05-13
PE20040592A1 (es)	2004-10-27
NO20052496D0 (no)	2005-05-24
JP4401296B2 (ja)	2010-01-20
ECSP055747A (es)	2005-07-06
CN1708493A (zh)	2005-12-14
PL376450A1 (en)	2005-12-27

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