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DK1367137T3 - Fremgangsmåder til isolering af biologiske målmaterialer ved anvendelse af magnetisk silika-partikler - Google Patents

Fremgangsmåder til isolering af biologiske målmaterialer ved anvendelse af magnetisk silika-partikler

Info

Publication number
DK1367137T3
DK1367137T3 DK03014689.8T DK03014689T DK1367137T3 DK 1367137 T3 DK1367137 T3 DK 1367137T3 DK 03014689 T DK03014689 T DK 03014689T DK 1367137 T3 DK1367137 T3 DK 1367137T3
Authority
DK
Denmark
Prior art keywords
methods
silica particles
target materials
biological target
magnetic silica
Prior art date
Application number
DK03014689.8T
Other languages
English (en)
Inventor
Craig E Smith
Charles K York
Original Assignee
Promega Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25134438&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK1367137(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Promega Corp filed Critical Promega Corp
Application granted granted Critical
Publication of DK1367137T3 publication Critical patent/DK1367137T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1003—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor
    • C12N15/1006—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor by means of a solid support carrier, e.g. particles, polymers
    • C12N15/1013—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor by means of a solid support carrier, e.g. particles, polymers by using magnetic beads
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00—Nanotechnology
    • Y10S977/70—Nanostructure
    • Y10S977/832—Nanostructure having specified property, e.g. lattice-constant, thermal expansion coefficient
    • Y10S977/838—Magnetic property of nanomaterial
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00—Nanotechnology
    • Y10S977/902—Specified use of nanostructure
    • Y10S977/904—Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00—Nanotechnology
    • Y10S977/902—Specified use of nanostructure
    • Y10S977/904—Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
    • Y10S977/915—Therapeutic or pharmaceutical composition
    • Y10S977/916—Gene therapy
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00—Nanotechnology
    • Y10S977/902—Specified use of nanostructure
    • Y10S977/904—Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
    • Y10S977/92—Detection of biochemical
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00—Nanotechnology
    • Y10S977/902—Specified use of nanostructure
    • Y10S977/904—Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
    • Y10S977/924—Specified use of nanostructure for medical, immunological, body treatment, or diagnosis using nanostructure as support of dna analysis
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00—Nanotechnology
    • Y10S977/902—Specified use of nanostructure
    • Y10S977/932—Specified use of nanostructure for electronic or optoelectronic application
    • Y10S977/953—Detector using nanostructure
    • Y10S977/96—Of magnetic property

Landscapes

  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Plant Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Immunology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Compounds Of Iron (AREA)
  • Silicon Compounds (AREA)
DK03014689.8T 1997-01-21 1998-01-21 Fremgangsmåder til isolering af biologiske målmaterialer ved anvendelse af magnetisk silika-partikler DK1367137T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/785,097 US6027945A (en) 1997-01-21 1997-01-21 Methods of isolating biological target materials using silica magnetic particles
EP98908435A EP0895546B1 (en) 1997-01-21 1998-01-21 Methods of isolating biological target materials using silica magnetic particles

Publications (1)

Publication Number Publication Date
DK1367137T3 true DK1367137T3 (da) 2010-07-12

Family

ID=25134438

Family Applications (1)

Application Number Title Priority Date Filing Date
DK03014689.8T DK1367137T3 (da) 1997-01-21 1998-01-21 Fremgangsmåder til isolering af biologiske målmaterialer ved anvendelse af magnetisk silika-partikler

Country Status (9)

Country Link
US (5) US6027945A (da)
EP (2) EP0895546B1 (da)
JP (1) JP3253638B2 (da)
AU (1) AU732756B2 (da)
BR (1) BR9805897A (da)
CA (1) CA2249393A1 (da)
DE (3) DE69841555D1 (da)
DK (1) DK1367137T3 (da)
WO (1) WO1998031840A1 (da)

Families Citing this family (265)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9425138D0 (en) 1994-12-12 1995-02-08 Dynal As Isolation of nucleic acid
DE19520398B4 (de) * 1995-06-08 2009-04-16 Roche Diagnostics Gmbh Magnetisches Pigment
KR100463475B1 (ko) 1995-06-08 2005-06-22 로셰 디아그노스틱스 게엠베하 자기성피그먼트
JP2965131B2 (ja) * 1995-07-07 1999-10-18 東洋紡績株式会社 核酸結合用磁性担体およびそれを用いる核酸単離方法
WO1997040385A1 (en) 1996-04-25 1997-10-30 Bioarray Solutions, Llc Light-controlled electrokinetic assembly of particles near surfaces
KR100464870B1 (ko) 1997-01-21 2005-01-05 더블유.알. 그레이스 앤드 캄파니-콘. 자성 물질상의 실리카 흡착제
US20050287583A1 (en) * 1997-01-21 2005-12-29 Promega Corporation Methods and kits for isolating biological target materials using silica magnetic particles
US6027945A (en) 1997-01-21 2000-02-22 Promega Corporation Methods of isolating biological target materials using silica magnetic particles
WO1998050567A1 (en) * 1997-05-02 1998-11-12 Abbott Laboratories Reagents and methods useful for detecting diseases of the prostate
DE19743518A1 (de) 1997-10-01 1999-04-15 Roche Diagnostics Gmbh Automatisierbare universell anwendbare Probenvorbereitungsmethode
US20080064108A1 (en) * 1997-12-10 2008-03-13 Tony Baker Urine Preservation System
US7569342B2 (en) * 1997-12-10 2009-08-04 Sierra Molecular Corp. Removal of molecular assay interferences
DE69815282T2 (de) * 1997-12-25 2004-05-06 Tosoh Corp., Shinnanyo Magnetischer Träger, seine Herstellung, und Verfahren zum Extrahieren von Nukleinsäuren
US7078224B1 (en) 1999-05-14 2006-07-18 Promega Corporation Cell concentration and lysate clearance using paramagnetic particles
US6534262B1 (en) 1998-05-14 2003-03-18 Whitehead Institute For Biomedical Research Solid phase technique for selectively isolating nucleic acids
EP0969090A1 (en) * 1998-05-27 2000-01-05 QIAGEN GmbH Rapid and simple process for isolation of circular nucleic acids
US6368866B1 (en) 1998-08-03 2002-04-09 Reference Diagnostics, Inc. Rapid separation assay for total iron binding capacity
US6703228B1 (en) * 1998-09-25 2004-03-09 Massachusetts Institute Of Technology Methods and products related to genotyping and DNA analysis
DE69929542T2 (de) 1998-10-27 2006-09-14 Affymetrix, Inc., Santa Clara Komplexitätsmanagement und analyse genomischer dna
US5973138A (en) * 1998-10-30 1999-10-26 Becton Dickinson And Company Method for purification and manipulation of nucleic acids using paramagnetic particles
ATE248911T1 (de) * 1998-11-30 2003-09-15 Roche Diagnostics Gmbh Magnetische partikel zur reinigung von nukleinsäuren
FI990082A0 (fi) * 1999-01-18 1999-01-18 Labsystems Oy Puhdistusprosessi magneettipartikkeleita käyttäen
WO2000042410A1 (en) * 1999-01-18 2000-07-20 Precision System Science Co., Ltd. Concentration device using magnetic particles and method therefor
WO2000043199A1 (en) * 1999-01-20 2000-07-27 Reference Diagnostics, Inc. Magnetically responsive gel particle
US6310199B1 (en) 1999-05-14 2001-10-30 Promega Corporation pH dependent ion exchange matrix and method of use in the isolation of nucleic acids
AU778486B2 (en) * 1999-05-14 2004-12-09 Promega Corporation Cell concentration and lysate clearance using paramagnetic particles
EP1621618B1 (en) 1999-05-14 2011-10-26 Promega Corporation Cell concentration and lysate clearance using paramagnetic particles
US6270970B1 (en) * 1999-05-14 2001-08-07 Promega Corporation Mixed-bed solid phase and its use in the isolation of nucleic acids
EP1069131B1 (en) * 1999-07-15 2006-03-15 Qiagen GmbH Methods for separating particulate substrates from solution while minimizing particle loss
DE19937607A1 (de) * 1999-08-09 2001-02-15 Bilatec Ges Zur Entwicklung Bi Reagenzienkit zur Isolierung von Nukleinsäuren
EP1204741B1 (en) * 1999-08-20 2004-10-20 Promega Corporation Simultaneous isolation and quantitation of dna
EP1510578A3 (en) * 1999-08-20 2005-03-16 Promega Corporation Simultaneous isolation and quantitation of dna
US6841393B2 (en) 1999-10-19 2005-01-11 Kimberly-Clark Worldwide, Inc. Selective removal of contaminants from a surface using colored particles and articles having magnets
US6503761B1 (en) * 1999-10-19 2003-01-07 Kimberly-Clark Worldwide, Inc. Selective removal of contaminants from a surface using articles having magnets
US6958225B2 (en) 1999-10-27 2005-10-25 Affymetrix, Inc. Complexity management of genomic DNA
DE60025529T2 (de) * 1999-11-17 2006-08-24 Roche Diagnostics Gmbh Magnetische glasteilchen, herstellungsverfahren und benutzung
US6936414B2 (en) * 1999-12-22 2005-08-30 Abbott Laboratories Nucleic acid isolation method and kit
WO2001071732A2 (en) * 2000-03-24 2001-09-27 Qiagen Gmbh Porous ferro- or ferrimagnetic glass particles for isolating molecules
JP4792192B2 (ja) * 2000-05-19 2011-10-12 ベクトン・ディキンソン・アンド・カンパニー 液体サンプル内の磁気応答性粒子を操作し、サンプルからｄｎａ又はｒｎａを収集するシステム及び方法
US6672458B2 (en) * 2000-05-19 2004-01-06 Becton, Dickinson And Company System and method for manipulating magnetically responsive particles fluid samples to collect DNA or RNA from a sample
GB0013658D0 (en) * 2000-06-05 2000-07-26 Dynal Asa Nucleic acid isolation
US9709559B2 (en) 2000-06-21 2017-07-18 Bioarray Solutions, Ltd. Multianalyte molecular analysis using application-specific random particle arrays
AU2001272993B2 (en) * 2000-06-21 2005-03-10 Bioarray Solutions, Ltd. Multianalyte molecular analysis
AU2001276830A1 (en) * 2000-06-23 2002-01-08 Irm, Llc Method and apparatus for performing an assay
US20050266494A1 (en) * 2000-09-06 2005-12-01 Hodge Timothy A System and method for computer network ordering of biological testing
AU2001288689A1 (en) * 2000-09-06 2002-03-22 Timothy A. Hodge System, method and apparatus for transgenic and targeted mutagenesis screening
US7011943B2 (en) * 2000-09-06 2006-03-14 Transnetyx, Inc. Method for detecting a designated genetic sequence in murine genomic DNA
US20030087286A1 (en) * 2000-09-06 2003-05-08 Hodge Timothy A. Isolation of eukaryotic genomic DNA using magnetically responsive solid functionalized particles
KR20020065509A (ko) * 2000-09-06 2002-08-13 티모시 에이. 호지 유전자이식 및 표적 돌연변이유발 스크리닝을 위한시스템, 방법 및 장치
US20050272085A1 (en) * 2000-09-06 2005-12-08 Hodge Timothy A Methods for forensic and congenic screening
US7494817B2 (en) * 2000-09-06 2009-02-24 Transnet Yx, Inc. Methods for genotype screening using magnetic particles
US20030082605A1 (en) * 2000-09-06 2003-05-01 Hodge Timothy A. Genomic DNA detection method and system thereof
US20050239125A1 (en) * 2000-09-06 2005-10-27 Hodge Timothy A Methods for genotype screening
US20030207289A1 (en) * 2001-09-04 2003-11-06 Hodge Timothy A. Detection of genetic sequences using a bipartite probe
CA2428532C (en) * 2000-11-13 2009-05-19 Promega Corporation Lysate clearance and nucleic acid isolation using silanized silica matrices
WO2002044414A2 (en) * 2000-11-28 2002-06-06 Promega Corporation Purification of dna sequencing reactions using silica magnetic particles
US6607667B2 (en) * 2000-11-28 2003-08-19 W. R. Grace & Co.-Conn. Method for adsorbing substances using silica adsorbent on magnetic substrate
US6794141B2 (en) * 2000-12-22 2004-09-21 Arcturus Bioscience, Inc. Nucleic acid amplification
JP4065405B2 (ja) * 2001-01-19 2008-03-26 デー エル エム ドクトル ミュラー アクチェンゲゼルシャフト プラスミドｄｎａを含有する細胞溶解物を製造するためのバイオマスの処理法
US6855499B1 (en) 2001-02-16 2005-02-15 Cortex Biochem, Inc. Magnetic isolation and purification of nucleic acids
DE60137652D1 (de) 2001-02-16 2009-03-26 Cortex Biochem Inc Magnetische isolierung und reinigung von nukleinsäuren
US20030022203A1 (en) * 2001-04-23 2003-01-30 Rajan Kumar Cellular Arrays
US6656587B2 (en) 2001-05-02 2003-12-02 Phillips Plastics Corporation Composite particles
US6849186B2 (en) * 2001-05-02 2005-02-01 Phillips Plastic Corporation Composite particles
US7262063B2 (en) 2001-06-21 2007-08-28 Bio Array Solutions, Ltd. Directed assembly of functional heterostructures
US7217513B2 (en) * 2001-07-10 2007-05-15 Massachusetts Institute Of Technology Apparatus and method for isolating a nucleic acid from a sample
US7285412B2 (en) * 2001-07-27 2007-10-23 Surface Logix Inc. Device for magnetic immobilization of cells
US7169577B2 (en) * 2001-07-27 2007-01-30 Surface Logix, Inc. Cell isolation and screening device and method of using same
US7169578B2 (en) * 2001-07-27 2007-01-30 Surface Logix, Inc. Cell isolation and screening device and method of using same
US20030040129A1 (en) * 2001-08-20 2003-02-27 Shah Haresh P. Binding assays using magnetically immobilized arrays
US20060014186A1 (en) * 2001-09-04 2006-01-19 Hodge Timothy A Methods for genotype screening of a strain disposed on an adsorbent carrier
US20040137449A1 (en) * 2001-10-05 2004-07-15 Nargessi R D Magnetic isolation and purification of nucleic acids
EP1463825B1 (en) 2001-10-15 2017-12-06 BioArray Solutions Ltd. Multiplexed analysis of polymorphic loci by concurrent interrogation and enzyme-mediated detection
DE60230788D1 (de) 2001-11-06 2009-02-26 Cortex Biochem Inc Isolierung und aufreinigung von nukleinsäuren
CA2473376A1 (en) 2002-01-16 2003-07-31 Dynal Biotech Asa Method for isolating nucleic acids and protein from a single sample
EP1599489A4 (en) * 2002-02-13 2007-01-03 Medimolecular Pty Ltd PROCESS FOR ISOLATING NUCLEIC ACIDS FROM SEQUET SAMPLES
US20060246434A1 (en) * 2002-03-15 2006-11-02 Erlander Mark G Nucleic acid amplification
US7214427B2 (en) * 2002-03-21 2007-05-08 Aviva Biosciences Corporation Composite beads comprising magnetizable substance and electro-conductive substance
GB0207975D0 (en) * 2002-04-05 2002-05-15 Genovision As Isolating nucleic acid
GB0210766D0 (en) * 2002-05-10 2002-06-19 Genovision As Isolating nucleic acid
ATE375512T1 (de) * 2002-06-27 2007-10-15 Toyo Boseki Magnetischer träger für biologische substanzen, verfahren zur seiner produktion und seiner verwendung zur isolierung dieser biologischen substanzen
GB0215185D0 (en) 2002-07-01 2002-08-07 Genovision As Binding a target substance
JP2005532072A (ja) * 2002-07-10 2005-10-27 マサチューセッツ・インスティテュート・オブ・テクノロジー サンプルから核酸を単離するための装置および方法
WO2004013633A2 (en) * 2002-07-29 2004-02-12 Axxima Pharmaceuticals Ag Method for isolating atp binding proteins by means of immobolized protein inhibitors
US7183104B1 (en) 2002-08-23 2007-02-27 Duane Morris Llp Separator and particle detection system
US7176036B2 (en) * 2002-09-20 2007-02-13 Arrowhead Center, Inc. Electroactive microspheres and methods
US7526114B2 (en) 2002-11-15 2009-04-28 Bioarray Solutions Ltd. Analysis, secure access to, and transmission of array images
GB0229287D0 (en) * 2002-12-16 2003-01-22 Dna Res Innovations Ltd Polyfunctional reagents
US7601491B2 (en) 2003-02-06 2009-10-13 Becton, Dickinson And Company Pretreatment method for extraction of nucleic acid from biological samples and kits therefor
US20040157219A1 (en) * 2003-02-06 2004-08-12 Jianrong Lou Chemical treatment of biological samples for nucleic acid extraction and kits therefor
JP2004000922A (ja) * 2003-03-26 2004-01-08 Toyobo Co Ltd 核酸またはタンパク質抽出用シリカ粒子組成物
DE602004030785D1 (de) 2003-05-19 2011-02-10 Univ Brandeis Verfahren, kits und vorrichtungen zur prozessierung von nukleinsäuren
JP4612789B2 (ja) * 2003-05-29 2011-01-12 キヤノン株式会社 Ｄｎａハイブリッド及びｄｎａハイブリッドを用いた環境浄化システム
EP1633869A1 (en) * 2003-06-04 2006-03-15 Qiagen AS Method for sequentially isolating dna and rna from the same nucleic acid-containing sample
US20050042660A1 (en) * 2003-07-31 2005-02-24 Hall Gerald Edward Devices and methods for isolating RNA
GB0319671D0 (en) * 2003-08-21 2003-09-24 Secr Defence Apparatus for processing a fluid sample
EP1510577A1 (en) * 2003-08-29 2005-03-02 Qiagen GmbH Method for magnetic bead isolation of nucleic acids
US7927796B2 (en) * 2003-09-18 2011-04-19 Bioarray Solutions, Ltd. Number coding for identification of subtypes of coded types of solid phase carriers
PT1664722E (pt) * 2003-09-22 2011-12-28 Bioarray Solutions Ltd Polielectrólito imobilizado à superfície com grupos funcionais múltiplos capazes de se ligarem covalentemente às biomoléculas
US20050089916A1 (en) * 2003-10-28 2005-04-28 Xiongwu Xia Allele assignment and probe selection in multiplexed assays of polymorphic targets
AU2004286252A1 (en) 2003-10-28 2005-05-12 Bioarray Solutions Ltd. Optimization of gene expression analysis using immobilized capture probes
ES2533876T3 (es) 2003-10-29 2015-04-15 Bioarray Solutions Ltd Análisis multiplexado de ácidos nucleicos mediante fragmentación de ADN bicatenario
US20050106577A1 (en) * 2003-11-17 2005-05-19 Hashem Akhavan-Tafti Cleavable solid phases for isolating nucleic acids
US20050136477A1 (en) * 2003-11-17 2005-06-23 Hashem Akhavan-Tafti Methods for isolating nucleic acids from biological and cellular materials
US20050106602A1 (en) * 2003-11-17 2005-05-19 Hashem Akhavan-Tafti Simplified methods for isolating nucleic acids from cellular materials
US20050106589A1 (en) * 2003-11-17 2005-05-19 Hashem Akhavan-Tafti Compositions and methods for releasing nucleic acids from solid phase binding materials
US20050106576A1 (en) * 2003-11-17 2005-05-19 Hashem Akhavan-Tafti Methods of using cleavable solid phases for isolating nucleic acids
DE10358137A1 (de) * 2003-12-12 2005-07-07 Merck Patent Gmbh Verfahren und Kit zur Isolierung von RNA
EP1709197A4 (en) * 2003-12-30 2007-07-04 Sigma Aldrich Co RAPID PREPARATION OF NUCLEIC ACIDS BY ENZYMATIC DEPENDENCE
JP2007522807A (ja) * 2004-02-18 2007-08-16 アプレラ コーポレイション 高分子電解質コーティングされたサイズ排除イオン交換粒子
US8426126B2 (en) 2004-03-18 2013-04-23 Applied Biosystems, Llc Modified surfaces as solid supports for nucleic acid purification
US20050239091A1 (en) * 2004-04-23 2005-10-27 Collis Matthew P Extraction of nucleic acids using small diameter magnetically-responsive particles
US20050236299A1 (en) * 2004-04-27 2005-10-27 Mark Weber Folded material containment packages and related methods of packaging folded material products
NL1026271C2 (nl) * 2004-05-26 2005-11-30 Keygene Nv Werkwijze en inrichting voor het isoleren van nucleïnezuur uit nucleïnezuur bevattend materiaal.
WO2006004611A2 (en) * 2004-06-25 2006-01-12 Invitrogen Corporation Separation of nucleic acid
JP4476050B2 (ja) * 2004-06-30 2010-06-09 株式会社ニデック 視野計
US7363170B2 (en) * 2004-07-09 2008-04-22 Bio Array Solutions Ltd. Transfusion registry network providing real-time interaction between users and providers of genetically characterized blood products
JP4798971B2 (ja) * 2004-07-30 2011-10-19 キヤノン株式会社 磁性粒子集合体およびそれを用いた標的核酸の抽出装置および抽出方法
EP1776458A2 (en) 2004-07-30 2007-04-25 Agencourt Bioscience Corporation Methods of isolating nucleic acids using multifunctional group-coated solid phase carriers
US7848889B2 (en) 2004-08-02 2010-12-07 Bioarray Solutions, Ltd. Automated analysis of multiplexed probe-target interaction patterns: pattern matching and allele identification
CA2839092C (en) * 2004-08-03 2018-04-03 Becton, Dickinson And Company Use of magnetic material to direct isolation of compounds and fractionation of multipart samples
WO2006017427A1 (en) * 2004-08-03 2006-02-16 Becton, Dickinson And Company Use of magnetic material to fractionate samples
ATE527338T1 (de) 2004-08-03 2011-10-15 Novartis Vaccines & Diagnostic Verfahren zur gewinnung von nukleinsäuren durch lyse mikrobieller proben
EP1623996A1 (en) * 2004-08-06 2006-02-08 Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts Improved method of selecting a desired protein from a library
US20060099605A1 (en) * 2004-11-11 2006-05-11 Hall Gerald E Jr Devices and methods for isolating RNA
US7320891B2 (en) * 2004-09-10 2008-01-22 Promega Corporation Methods and kits for isolating sperm cells
US7166680B2 (en) * 2004-10-06 2007-01-23 Advanced Cardiovascular Systems, Inc. Blends of poly(ester amide) polymers
EP1650297B1 (en) * 2004-10-19 2011-04-13 Samsung Electronics Co., Ltd. Method and apparatus for the rapid disruption of cells or viruses using micro magnetic beads and laser
DE102005002343A1 (de) 2005-01-18 2006-07-27 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Verfahren zur spezifischen oder unspezifischen Separation von Zellen und/oder Viren aus flüssigen Medien und dessen Verwendung
US7964380B2 (en) * 2005-01-21 2011-06-21 Argylia Technologies Nanoparticles for manipulation of biopolymers and methods of thereof
US20060166223A1 (en) * 2005-01-26 2006-07-27 Reed Michael W DNA purification and analysis on nanoengineered surfaces
EP1690938A1 (de) * 2005-02-11 2006-08-16 Qiagen GmbH Verfahren zur Isolierung von Nukleinsäuren, wobei die Nukleinsäuren bei erhöhter Temperatur an einer Matrix immobilisiert werden
ITRM20050067A1 (it) * 2005-02-17 2006-08-18 Istituto Naz Per Le Malattie I Metodo per la rivelazione di acidi nucleici virali o di origine virale nelle urine.
ITRM20050068A1 (it) * 2005-02-17 2006-08-18 Istituto Naz Per Le Malattie I Metodo per la rivelazione di acidi nucleici di agenti patogeni batterici o di parassiti nelle urine.
US7914982B2 (en) * 2005-02-17 2011-03-29 Trovagene, Inc. Methods for detecting pathogen specific nucleic acids in urine
US20060223071A1 (en) * 2005-04-01 2006-10-05 Wisniewski Michele E Methods, compositions, and kits for detecting nucleic acids in a single vessel
US8628918B2 (en) * 2005-05-09 2014-01-14 Affymetrix, Inc. Multiplex capture of nucleic acids
US8632970B2 (en) 2005-05-09 2014-01-21 Affymetrix, Inc. Multiplex capture of nucleic acids
EP1880025B1 (en) 2005-05-12 2011-03-16 Affymetrix, Inc. Multiplex branched-chain dna assays
US20060269929A1 (en) * 2005-05-26 2006-11-30 Hall Gerald E Jr Methods and kits for DNA purification on polymeric membranes at low ionic strength
US20060270843A1 (en) * 2005-05-26 2006-11-30 Hall Gerald E Jr Methods for isolation of nucleic acids
US8486629B2 (en) 2005-06-01 2013-07-16 Bioarray Solutions, Ltd. Creation of functionalized microparticle libraries by oligonucleotide ligation or elongation
EP2460893B1 (en) * 2005-06-20 2013-08-28 Advanced Cell Diagnostics, Inc. Multiplex detection of nucleic acids
JP2009500019A (ja) * 2005-07-01 2009-01-08 プロメガ・コーポレーション 生体分子の精製のための浮遊性粒子のネットワーク、及び生体分子の精製のための浮遊性粒子又は浮遊性粒子のネットワークの使用
US20070072195A1 (en) * 2005-09-29 2007-03-29 Constantine Haralambopoulos Bio-commemorative article incorporating amplified genetic material
US7927798B2 (en) * 2005-10-05 2011-04-19 Panomics, Inc. Detection of nucleic acids from whole blood
US8372340B2 (en) 2005-10-19 2013-02-12 Luminex Corporation Apparatus and methods for integrated sample preparation, reaction and detection
US7727473B2 (en) 2005-10-19 2010-06-01 Progentech Limited Cassette for sample preparation
US7754148B2 (en) 2006-12-27 2010-07-13 Progentech Limited Instrument for cassette for sample preparation
US20070092403A1 (en) * 2005-10-21 2007-04-26 Alan Wirbisky Compact apparatus, compositions and methods for purifying nucleic acids
US8030034B2 (en) * 2005-12-09 2011-10-04 Promega Corporation Nucleic acid purification with a binding matrix
CN101384715A (zh) * 2006-02-15 2009-03-11 东曹株式会社 从生物材料中提取核酸的方法
US20070254284A1 (en) * 2006-05-01 2007-11-01 Biwei Zhao A nucleic acid detection method
EP2041318A2 (en) * 2006-06-26 2009-04-01 Blood Cell Storage, Inc. Device and method for extraction and analysis of nucleic acids from biological samples
EP2054501A4 (en) * 2006-10-06 2010-11-03 Promega Corp METHODS AND KITS FOR ISOLATING CELLS
EP1911844A1 (en) * 2006-10-10 2008-04-16 Qiagen GmbH Methods and kit for isolating nucleic acids
EP3604553A3 (en) 2006-11-03 2020-04-29 Siemens Healthcare Diagnostics Inc. Random access system for polymerase chain reaction testing
WO2008071384A1 (en) * 2006-12-13 2008-06-19 Roche Diagnostics Gmbh Use of tde for the isolation of nucleic acids
WO2008071385A2 (en) * 2006-12-13 2008-06-19 Roche Diagnostics Gmbh Use of acetals for the isolation of nucleic acids
CN101627065B (zh) * 2006-12-21 2012-05-23 茵维特罗根戴纳股份公司 颗粒和其在分离核酸的方法或分离磷蛋白的方法中的应用
US8993292B2 (en) * 2007-01-16 2015-03-31 Applied Biosystems Llc Methods and systems for differential extraction
US7960180B2 (en) * 2007-02-20 2011-06-14 University Of Notre Dame Du Lac Methods and apparatus to capture and release microbe particles using amino-functionalized silica
WO2008134470A2 (en) * 2007-04-25 2008-11-06 3M Innovative Properties Company Methods for nucleic acid amplification
AU2008273030B2 (en) * 2007-06-29 2013-01-17 Becton, Dickinson And Company Methods for extraction and purification of components of biological samples
US7868145B2 (en) * 2007-07-11 2011-01-11 Industrial Technology Research Institute Magnetic particles containing a copolymer core, magnetic layer and silicon layer
JP2010534476A (ja) 2007-07-23 2010-11-11 アプライド バイオシステムズ インコーポレイテッド 法医学的試料から精子核酸を回収するための方法
PL2195450T3 (pl) * 2007-08-22 2013-09-30 Trovagene Inc Sposób zastosowania miRNA do wykrywania in vivo śmierci komórki
CN101363045B (zh) * 2007-09-10 2012-10-17 厦门致善生物科技有限公司 一种用超微磁颗粒分离纯化生物靶物质的方法
US9388457B2 (en) 2007-09-14 2016-07-12 Affymetrix, Inc. Locus specific amplification using array probes
US8357296B2 (en) 2007-09-24 2013-01-22 Emd Millipore Corporation Centrifugal filter
WO2009068585A1 (en) * 2007-11-26 2009-06-04 Atonomics A/S Integrated separation and detection cartridge using magnetic particles with bimodal size distribution
WO2009117167A1 (en) * 2008-01-02 2009-09-24 Blood Cell Storage, Inc. Devices and processes for nucleic acid extraction
WO2009088987A2 (en) 2008-01-03 2009-07-16 The Johns Hopkins University Compositions and methods for polynucleotide extraction and methylation detection
KR101053023B1 (ko) * 2008-02-14 2011-08-01 (주)바이오니아 구형 실리카 자성입자 및 이의 제조방법
US9074244B2 (en) 2008-03-11 2015-07-07 Affymetrix, Inc. Array-based translocation and rearrangement assays
US20120149587A1 (en) * 2008-03-12 2012-06-14 University Of Virginia Patent Foundation Method for detecting nucleated cells
AU2009223122B2 (en) 2008-03-12 2014-12-11 University Of Virginia Patent Foundation Detection of polymeric analytes
DE102008029356A1 (de) * 2008-06-20 2009-12-24 Siemens Healthcare Diagnostics Gmbh Verfahren zur Aufreinigung von Nukleinsäuren, insbesondere aus fixiertem Gewebe
EP2147981A1 (en) * 2008-07-25 2010-01-27 Biotype AG Kit and method for evaluating detection properties in amplification reactions
US20100062518A1 (en) * 2008-09-09 2010-03-11 Sukanta Banerjee Concentrating White Blood Cells for DNA Extraction from a Leukodepleted Blood Sample
US8632671B2 (en) * 2008-10-03 2014-01-21 Board Of Regents, University Of Texas System Method for measuring carbon nanotubes taken-up by a plurality of living cells
AU2009313556A1 (en) * 2008-11-04 2010-05-14 Blood Cell Storage, Inc. Nucleic acid extraction on curved glass surfaces
US8846878B1 (en) 2009-01-23 2014-09-30 Cubrc Corporation Method and device for isolating a protein sample
US20110287951A1 (en) * 2009-01-30 2011-11-24 Emmert-Buck Michael R Methods and systems for purifying, transferring, and/or manipulating nucleic acids
DE102009001864A1 (de) * 2009-03-25 2010-09-30 Qiagen Gmbh Überschichtung zur Partikelabtrennung
DE102009022512A1 (de) * 2009-05-25 2010-12-02 Qiagen Gmbh Verfahren zur Reaktivierung von Silikaoberflächen zur Isolierung von Nukleinsäuren
US8222397B2 (en) 2009-08-28 2012-07-17 Promega Corporation Methods of optimal purification of nucleic acids and kit for use in performing such methods
US8039613B2 (en) * 2009-08-28 2011-10-18 Promega Corporation Methods of purifying a nucleic acid and formulation and kit for use in performing such methods
TW201113523A (en) * 2009-08-31 2011-04-16 Mbio Diagnostics Inc Integrated sample preparation and analyte detection
TW201113377A (en) 2009-09-01 2011-04-16 Basf Agrochemical Products Bv Herbicide-tolerant plants
US11096345B2 (en) 2009-09-01 2021-08-24 Basf Se Method for treating post-emergent rice
TWI407994B (zh) 2009-10-22 2013-09-11 Ind Tech Res Inst 分離核酸的方法、試劑及套組
BR112012015266A2 (pt) * 2009-12-23 2017-10-10 Koninl Philips Electronics Nv dispositivo configurado para receber uma amostra e método para determinar a presença de um analito em uma amostra
EP2345719A1 (en) 2010-01-18 2011-07-20 Qiagen GmbH Method for isolating small RNA
US20110223588A1 (en) * 2010-03-09 2011-09-15 Biosample Llc Solid Phase Nucleic Acid Extraction From Small Sample Volumes, and Release of Controlled Quantities
EP2407540A1 (en) 2010-07-15 2012-01-18 Qiagen GmbH Method for purifying a target nucleic acid
DE102010036111B4 (de) 2010-09-01 2013-08-29 Bundesrepublik Deutschland (Bundesamt für Ausrüstung, Informationstechnik und Nutzung der Bundeswehr) Vorbehandlungsverfahren zur Isolierung und Aufkonzentrierung von Nukleinsäuren aus einer Umweltprobe
US8658361B2 (en) 2010-10-21 2014-02-25 Advanced Cell Diagnostics, Inc. Ultra sensitive method for in situ detection of nucleic acids
EP2646551B1 (en) 2010-11-30 2017-06-07 Life Technologies Corporation Alkylene glycols and polymers and copolymers thereof for direct isolation of nucleic acid from embedded samples
CN103261424B (zh) 2010-12-16 2017-12-12 巴斯夫农业公司 对除草剂具有增强的耐受性的植物
EP2465934A1 (de) 2010-12-20 2012-06-20 Steffen Mergemeier Extraktion von Nukleinsäuren
US9051563B2 (en) 2011-01-14 2015-06-09 Zymo Research Corporation Nucleic acid purification
CN107338189B (zh) 2011-05-04 2021-02-02 卢米耐克斯公司 用于集成的样品制备、反应和检测的设备与方法
US8629264B2 (en) 2011-05-19 2014-01-14 Blood Cell Storage, Inc. Gravity flow fluidic device for nucleic acid extraction
US9304070B2 (en) 2011-07-13 2016-04-05 Emd Millipore Corporation All-in-one sample preparation device and method
DE102011054474B4 (de) 2011-07-20 2014-02-13 Stratec Biomedical Ag System zur Stabilisierung, Aufbewahrung und Lagerung einer Nukleinsäure
JP6096774B2 (ja) 2011-08-12 2017-03-15 キアゲン ゲゼルシャフト ミット ベシュレンクテル ハフツング 核酸を単離するための方法
WO2013116375A1 (en) 2012-01-30 2013-08-08 Exact Sciences Corporation Modification of dna on magnetic beads
EP2634254A1 (en) 2012-02-29 2013-09-04 QIAGEN GmbH Method for isolating nucleic acids from a food sample
US10041087B2 (en) 2012-06-19 2018-08-07 BASF Agro B.V. Plants having increased tolerance to herbicides
AR091489A1 (es) 2012-06-19 2015-02-11 Basf Se Plantas que tienen una mayor tolerancia a herbicidas inhibidores de la protoporfirinogeno oxidasa (ppo)
CN104540594B (zh) 2012-06-25 2019-07-02 通用医疗公司 使用高梯度磁场对粒子进行分类
EP2770056B1 (en) 2012-07-18 2017-05-31 Zymo Research Corporation Nucleic acid purification
FR2994184B1 (fr) 2012-08-02 2017-12-08 Biomerieux Sa Procedes de fonctionalisation et reactifs utilises dans de tels procedes utilisant un anhydride aza-isatoique ou un de ses derives, molecules biologiques ainsi traitees et kits
EP2888354B1 (en) 2012-08-21 2020-04-01 Qiagen GmbH Virus particle stabilisation and method for isolating viral nucleic acids
US20150225712A1 (en) 2012-08-21 2015-08-13 Qiagen Gmbh Method for isolating nucleic acids from a formaldehyde releaser stabilized sample
SG11201500655VA (en) 2012-09-03 2015-05-28 Qiagen Gmbh Method for isolating rna including small rna with high yield
CA2885263C (en) 2012-09-17 2021-11-16 W. R. Grace & Co.-Conn. Chromatography media and devices
GB201217405D0 (en) * 2012-09-28 2012-11-14 Fermentas Uab Protein removal agent
US10745686B2 (en) 2013-02-08 2020-08-18 Qiagen Gmbh Method for separating DNA by size
JP2016510872A (ja) * 2013-03-01 2016-04-11 スピノミックス エス．ア．Ｓｐｉｎｏｍｉｘ Ｓ．Ａ． 磁気粒子をベースとする分離および分析方法
CA2905425A1 (en) * 2013-03-13 2014-10-02 Abbott Molecular Inc. Methods of isolating nucleic acid using a lysis buffer containing ethanol
US9670479B2 (en) 2013-03-15 2017-06-06 F Cubed, LLC Sample preparation device and methods of use
JP5802237B2 (ja) * 2013-04-18 2015-10-28 三洋化成工業株式会社 磁性粒子及びその製造方法
UA123757C2 (uk) 2013-08-12 2021-06-02 Басф Агро Б. В. Мутована протопорфіриногеноксидаза, що надає рослинам стійкості до ппо-інгібуючого гербіциду
CA2920591A1 (en) 2013-08-12 2015-02-19 BASF Agro B.V. Plants having increased tolerance to herbicides
DE202014002379U1 (de) 2014-03-15 2014-08-19 Ruprecht-Karls-Universität Heidelberg DNA Stabilisierungssystem
WO2015150465A2 (en) 2014-04-03 2015-10-08 Basf Se Plants having increased tolerance to herbicides
WO2015168383A1 (en) 2014-05-02 2015-11-05 W. R. Grace & Co.-Conn. Functionalized support material and methods of making and using functionalized support material
KR102344395B1 (ko) * 2014-06-24 2021-12-29 (주)바이오니아 자성 입자를 이용한 핵산 분리 방법
US10000750B2 (en) 2014-10-09 2018-06-19 Promega Corporation Method of isolating nucleic acid
JP2017539080A (ja) 2014-10-23 2017-12-28 コーニング インコーポレイテッド 高分子被包磁性ナノ粒子
JP6773402B2 (ja) * 2014-11-04 2020-10-21 三洋化成工業株式会社 磁性シリカ粒子を用いた対象物質の分離方法
EP3059312A1 (en) 2015-02-20 2016-08-24 QIAGEN GmbH Nucleic acid extraction method
US9422596B1 (en) 2015-04-27 2016-08-23 Norgen Biotek Corp. Methods and columns for nucleic acid purification
KR101646610B1 (ko) 2015-05-28 2016-08-09 (주)바이오니아 생체 물질 정제용 고활성 실리카 자성나노입자 및 이의 제조 방법
EP3303582A1 (en) 2015-06-01 2018-04-11 Qiagen GmbH Electrophoresis assisted method and device for purifying a charged target molecule from a sample
EP3303580B1 (en) 2015-06-01 2020-11-18 Qiagen GmbH Electrophoresis assisted method for purifying a target nucleic acid using a delayed elution approach
EP3302784B1 (en) 2015-06-05 2021-10-06 W.R. Grace & Co.-Conn. Adsorbent bioprocessing clarification agents and methods of making and using the same
ES2906751T3 (es) 2015-06-05 2022-04-20 Qiagen Gmbh Método para separar el DNA por tamaño
EP3347490A1 (en) * 2015-09-11 2018-07-18 Corning Incorporated Compositions and methods for nucleic acid purification from blood samples
EP3362462B1 (en) 2015-10-12 2021-07-21 Advanced Cell Diagnostics, Inc. In situ detection of nucleotide variants in high noise samples, and compositions and methods related thereto
AR106452A1 (es) 2015-10-22 2018-01-17 Basf Se Plantas que tienen una mayor tolerancia a herbicidas
AR106931A1 (es) 2015-10-22 2018-03-07 Basf Se Plantas que tienen una mayor tolerancia a herbicidas
BR112018068934A2 (pt) 2016-04-29 2019-01-22 Basf Plant Science Co Gmbh método de modificação de moléculas de ácido nucleico alvo (na alvo) em células, molécula, molécula de funa recombinante, vetor e seu uso, sistema de vetor, sistema de modificação de na alvo em células, composição
TR201606310A2 (tr) 2016-05-12 2017-11-21 Akdeniz Ueniversitesi Genomik dna izolasyon yöntemi ve kiti.
AU2017266411B2 (en) 2016-05-20 2023-06-08 BASF Agro B.V. Dual transit peptides for targeting polypeptides
WO2018004309A1 (ko) 2016-06-30 2018-01-04 김성천 이중가닥 핵산 신호 프로브 및 이를 이용한 표적분자의 검출방법
CN109790153A (zh) 2016-07-27 2019-05-21 巴斯夫农业公司 具有增加的除草剂耐受性的植物
US10077465B2 (en) * 2016-09-13 2018-09-18 The United States Of America, As Represented By The Secretary Of The Navy Sorbents for extraction and stabilization of nucleic acids
EP3519093B1 (en) 2016-09-30 2021-03-10 Koninklijke Philips N.V. System for applying a reagent to a sample
SG10202100951SA (en) 2016-11-21 2021-03-30 Nanostring Technologies Inc Chemical compositions and methods of using same
CA3044728A1 (en) 2016-12-20 2018-06-28 BASF Agro B.V. Plants having increased tolerance to herbicides
EP3630971A1 (en) * 2017-05-22 2020-04-08 QIAGEN Healthcare Biotechnologies Systems Limited Improvements in the recovery of nucleic acids from solid supports
CN111148834B (zh) 2017-09-27 2024-06-11 凯杰有限公司 以高收率分离rna的方法
SG11202011274YA (en) 2018-05-14 2020-12-30 Nanostring Technologies Inc Chemical compositions and methods of using same
JP7428657B2 (ja) * 2018-10-26 2024-02-06 テルモ株式会社 標的物質の分離方法および定量方法
EP3968029A4 (en) * 2019-05-08 2023-01-18 Hitachi High-Tech Corporation Automatic analysis device pretreatment method
US11807909B1 (en) 2019-09-12 2023-11-07 Zymo Research Corporation Methods for species-level resolution of microorganisms
US20220396826A1 (en) * 2019-11-20 2022-12-15 Toray Industries, Inc. Nucleic acid separation method, detection method, nucleic acid purification column and method of producing same
WO2021246820A1 (ko) 2020-06-05 2021-12-09 주식회사 씨젠 호흡기 병원체 검출을 위한 검체수송 키트 및 이를 이용한 호흡기 병원체 검출방법
KR20220075978A (ko) 2020-11-30 2022-06-08 (주)바이오니아 중저 비유전율을 가진 화합물을 포함한 핵산 결합 완충액을 이용한 핵산 분리방법
WO2023075394A1 (ko) 2021-10-29 2023-05-04 주식회사 씨젠 검체 채취 스왑 도구 및 호흡기 병원체의 검출 방법
WO2024126113A1 (en) 2022-12-12 2024-06-20 BASF Agricultural Solutions Seed US LLC Plants having increased tolerance to herbicides
WO2024124348A1 (en) * 2022-12-15 2024-06-20 Stemcell Technologies Canada Inc. Methods for nucleic acid extraction

Family Cites Families (50)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4233169A (en) * 1979-04-13 1980-11-11 Corning Glass Works Porous magnetic glass structure
US4297337A (en) * 1979-04-13 1981-10-27 Corning Glass Works Solid-phase immunoassays using magnetic glass
US4395271A (en) * 1979-04-13 1983-07-26 Corning Glass Works Method for making porous magnetic glass and crystal-containing structures
DE3211309A1 (de) 1982-03-26 1983-09-29 Metin Dipl.-Ing. 6100 Darmstadt Colpan Chromatographisches verfahren zur isolierung von makromolekuelen
US5482834A (en) 1982-05-17 1996-01-09 Hahnemann University Evaluation of nucleic acids in a biological sample hybridization in a solution of chaotrophic salt solubilized cells
US4672040A (en) 1983-05-12 1987-06-09 Advanced Magnetics, Inc. Magnetic particles for use in separations
US4695393A (en) * 1983-05-12 1987-09-22 Advanced Magnetics Inc. Magnetic particles for use in separations
US4554088A (en) * 1983-05-12 1985-11-19 Advanced Magnetics Inc. Magnetic particles for use in separations
US4683202A (en) * 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
US5076950A (en) * 1985-12-20 1991-12-31 Syntex (U.S.A.) Inc. Magnetic composition for particle separation
US6027750A (en) * 1986-09-04 2000-02-22 Gautsch; James Systems and methods for the rapid isolation of nucleic acids
DE3639949A1 (de) 1986-11-22 1988-06-09 Diagen Inst Molekularbio Verfahren zur trennung von langkettigen nukleinsaeuren
US4767670A (en) 1987-01-21 1988-08-30 E. I. Du Pont De Nemours And Company Chromatographic supports for separation of oligonucleotides
EP0343934B1 (en) * 1988-05-24 1995-01-25 Anagen (U.K.) Limited Magnetically attractable particles and method of preparation
US5512439A (en) * 1988-11-21 1996-04-30 Dynal As Oligonucleotide-linked magnetic particles and uses thereof
US5075430A (en) * 1988-12-12 1991-12-24 Bio-Rad Laboratories, Inc. Process for the purification of DNA on diatomaceous earth
US5234809A (en) 1989-03-23 1993-08-10 Akzo N.V. Process for isolating nucleic acid
US5523231A (en) 1990-02-13 1996-06-04 Amersham International Plc Method to isolate macromolecules using magnetically attractable beads which do not specifically bind the macromolecules
US5243037A (en) * 1990-09-21 1993-09-07 E. I. Du Pont De Nemours And Company Poly(fluoroalkyl) sugar reagents for surface modification of supports
AU654323B2 (en) 1991-01-04 1994-11-03 Perseptive Biosystems, Inc. Sulfonamide bonded hydrophilic coating
US5155018A (en) * 1991-07-10 1992-10-13 Hahnemann University Process and kit for isolating and purifying RNA from biological sources
US5395498A (en) * 1991-11-06 1995-03-07 Gombinsky; Moshe Method for separating biological macromolecules and means therfor
US5734020A (en) 1991-11-20 1998-03-31 Cpg, Inc. Production and use of magnetic porous inorganic materials
US5610274A (en) * 1991-11-20 1997-03-11 Cpg, Inc. Production and use of magnetic porous inorganic materials
US5346994A (en) * 1992-01-28 1994-09-13 Piotr Chomczynski Shelf-stable product and process for isolating RNA, DNA and proteins
EP0555798B1 (en) 1992-02-13 1999-05-06 Becton, Dickinson and Company Hydrated celite and purification of DNA
WO1993025710A1 (en) * 1992-06-08 1993-12-23 Gen-Probe Incorporated Preparation of nucleic acid from mononuclear cells
US5316680A (en) 1992-10-21 1994-05-31 Cornell Research Foundation, Inc. Multimodal chromatographic separation media and process for using same
JP3615545B2 (ja) 1993-02-01 2005-02-02 キアゲン・エヌ・ブイ 第四級アンモニウム塩界面活性剤及びそのｒｎａの単離剤
DE4307262A1 (de) * 1993-03-02 1994-09-08 Christian Bergemann Magnetisches polymeres Siliciumdioxid
AU689815B2 (en) * 1993-08-30 1998-04-09 Promega Corporation Nucleic acid purification compositions and methods
US5990301A (en) 1994-02-07 1999-11-23 Qiagen Gmbh Process for the separation and purification of nucleic acids from biological sources
ATE187733T1 (de) 1994-02-07 2000-01-15 Qiagen Gmbh Verfahren zur herstellung endotoxinfreier oder an endotoxin abgereicherter nucleinsäuren und/oder oligonucleotide für die gentherapie
DE4420732A1 (de) * 1994-06-15 1995-12-21 Boehringer Mannheim Gmbh Vorrichtung zur Behandlung von Nukleinsäuren aus einer Probe
ATE191086T1 (de) * 1994-07-27 2000-04-15 Pilgrimm Herbert Superparamagnetische teilchen, verfahren zur herstellung und deren verwendung
US5582988A (en) 1994-09-15 1996-12-10 Johnson & Johnson Clinical Diagnostics, Inc. Methods for capture and selective release of nucleic acids using weakly basic polymer and amplification of same
US5652348A (en) 1994-09-23 1997-07-29 Massey University Chromatographic resins and methods for using same
US5660984A (en) * 1994-12-09 1997-08-26 Davis; Thomas E. DNA isolating apparatus comprising a non-porous DNA binding, anion exchange resin and methods of use thereof
DE19520398B4 (de) * 1995-06-08 2009-04-16 Roche Diagnostics Gmbh Magnetisches Pigment
JP2965131B2 (ja) * 1995-07-07 1999-10-18 東洋紡績株式会社 核酸結合用磁性担体およびそれを用いる核酸単離方法
US5783686A (en) * 1995-09-15 1998-07-21 Beckman Instruments, Inc. Method for purifying nucleic acids from heterogenous mixtures
SE9600590D0 (sv) 1996-02-19 1996-02-19 Pharmacia Biotech Ab Sätt för kromatografisk separation av peptider och nukleinsyra samt ny högaffin jonbytesmatris
US5904848A (en) 1996-02-21 1999-05-18 Cpg, Inc. Controlled pore glass-synthetic resin membrane
EP0929694A4 (en) * 1996-03-15 2002-05-02 Penn State Res Found DETECTION OF TUMOR-RELATED EXTRACELLULAR NUCLEIC ACID USING PLASMA OR BLOOD SERUM USING NUCLEIC ACID AMPLIFICATION TESTS
JPH09327291A (ja) * 1996-06-11 1997-12-22 Toyobo Co Ltd Ｒｎａの抽出精製方法
JP3940935B2 (ja) * 1996-06-11 2007-07-04 東洋紡績株式会社 プラスミドｄｎａの抽出精製方法
KR100464870B1 (ko) 1997-01-21 2005-01-05 더블유.알. 그레이스 앤드 캄파니-콘. 자성 물질상의 실리카 흡착제
US6027945A (en) 1997-01-21 2000-02-22 Promega Corporation Methods of isolating biological target materials using silica magnetic particles
JP4196227B2 (ja) 1997-05-20 2008-12-17 東洋紡績株式会社 核酸またはタンパク質抽出用シリカ粒子組成物
WO2000050564A2 (en) * 1999-02-26 2000-08-31 Myriad Genetics, Inc. Method for extracting dna from dried specimens

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JPH11509742A (ja) 1999-08-31
US6673631B1 (en) 2004-01-06
CA2249393A1 (en) 1998-07-23
US20040086930A1 (en) 2004-05-06
EP0895546A4 (en) 2002-03-20
AU6647598A (en) 1998-08-07
JP3253638B2 (ja) 2002-02-04
DE895546T1 (de) 2002-10-17
US6368800B1 (en) 2002-04-09
EP0895546B1 (en) 2003-08-27
EP1367137A1 (en) 2003-12-03
DE69841555D1 (de) 2010-04-22
EP1367137B1 (en) 2010-03-10
DE69817484D1 (de) 2003-10-02
BR9805897A (pt) 1999-08-24
US20020086326A1 (en) 2002-07-04
EP0895546A1 (en) 1999-02-10
DE69817484T2 (de) 2004-06-17
US6027945A (en) 2000-02-22
AU732756B2 (en) 2001-04-26
WO1998031840A1 (en) 1998-07-23

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