DK1265605T3 - Farmaceutiske sammensætninger omfattende peptidmimetisk, cyklisk beta-drejningsforbindelse - Google Patents

Farmaceutiske sammensætninger omfattende peptidmimetisk, cyklisk beta-drejningsforbindelse

Info

Publication number: DK1265605T3
Authority: DK; Denmark
Prior art keywords: trka; extracellular domain; pharmaceutical compositions; compounds; peptide mimetic
Prior art date: 2000-01-18

Application number

DK01942551T

Other languages

Danish (da)

English (en)

Inventor

Kevin Burgess

Horacio Uri Saragovi

Original Assignee

Univ Mcgill

Texas A & M Univ Sys

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-01-18

Filing date

2001-01-18

Publication date

2007-02-12

2001-01-18 Application filed by Univ Mcgill, Texas A & M Univ Sys filed Critical Univ Mcgill

2007-02-12 Application granted granted Critical

2007-02-12 Publication of DK1265605T3 publication Critical patent/DK1265605T3/da

Links

150000001875 compounds Chemical class 0.000 title abstract 5
125000004122 cyclic group Chemical group 0.000 title 1
239000008194 pharmaceutical composition Substances 0.000 title 1
108090000765 processed proteins & peptides Proteins 0.000 title 1
101150111783 NTRK1 gene Proteins 0.000 abstract 4
102000007339 Nerve Growth Factor Receptors Human genes 0.000 abstract 2
108010032605 Nerve Growth Factor Receptors Proteins 0.000 abstract 2
239000003446 ligand Substances 0.000 abstract 2
230000001537 neural effect Effects 0.000 abstract 2
239000000816 peptidomimetic Substances 0.000 abstract 2
102000004022 Protein-Tyrosine Kinases Human genes 0.000 abstract 1
108090000412 Protein-Tyrosine Kinases Proteins 0.000 abstract 1
239000000556 agonist Substances 0.000 abstract 1
239000005557 antagonist Substances 0.000 abstract 1
230000004069 differentiation Effects 0.000 abstract 1
239000002831 pharmacologic agent Substances 0.000 abstract 1
102000004169 proteins and genes Human genes 0.000 abstract 1
108090000623 proteins and genes Proteins 0.000 abstract 1
150000003384 small molecules Chemical class 0.000 abstract 1
230000008685 targeting Effects 0.000 abstract 1
230000001228 trophic effect Effects 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Engineering & Computer Science (AREA)
Gastroenterology & Hepatology (AREA)
Bioinformatics & Cheminformatics (AREA)
Immunology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

DK01942551T 2000-01-18 2001-01-18 Farmaceutiske sammensætninger omfattende peptidmimetisk, cyklisk beta-drejningsforbindelse DK1265605T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US17648200P	2000-01-18	2000-01-18
PCT/CA2001/000043 WO2001052843A1 (fr)	2000-01-18	2001-01-18	Composes cycliques peptidomimetiques a coude beta

Publications (1)

Publication Number	Publication Date
DK1265605T3 true DK1265605T3 (da)	2007-02-12

Family

ID=22644525

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK01942551T DK1265605T3 (da)	2000-01-18	2001-01-18	Farmaceutiske sammensætninger omfattende peptidmimetisk, cyklisk beta-drejningsforbindelse

Country Status (9)

Country	Link
US (1)	US6881719B2 (fr)
EP (1)	EP1265605B1 (fr)
AT (1)	ATE340571T1 (fr)
AU (1)	AU2001228212A1 (fr)
CA (1)	CA2397670C (fr)
DE (1)	DE60123399T2 (fr)
DK (1)	DK1265605T3 (fr)
ES (1)	ES2273849T3 (fr)
WO (1)	WO2001052843A1 (fr)

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AUPR604401A0 (en)	2001-06-29	2001-07-26	University Of Wollongong, The	Peptoid compounds
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US9498530B2 (en)	2002-12-24	2016-11-22	Rinat Neuroscience Corp.	Methods for treating osteoarthritis pain by administering a nerve growth factor antagonist and compositions containing the same
PT2263692T (pt)	2002-12-24	2018-11-28	Rinat Neuroscience Corp	Anticorpos anti-ngf e métodos de utilização dos mesmos
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ITRM20030601A1 (it) *	2003-12-24	2005-06-25	Lay Line Genomics Spa	Metodo per l'umanizzazione di anticorpi e anticorpi umanizzati con esso ottenuti.
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WO2006005740A2 (fr) *	2004-07-14	2006-01-19	Janssen Pharmaceutica N.V.	Essai de depistage de p75ntr
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US20110230479A1 (en) *	2005-04-15	2011-09-22	Longo Frank M	Neurotrophin mimetics and uses thereof
JP2008536844A (ja) *	2005-04-15	2008-09-11	ザユニバーシティオブノースカロライナアットチャペルヒル	ニューロトロフィン類似体を用いた細胞生存促進法
ITRM20050290A1 (it) *	2005-06-07	2006-12-08	Lay Line Genomics Spa	Uso di molecole in grado di inibire il legame tra ngf e il suo recettore trka come analgesici ad effetto prolungato.
US8686045B2 (en)	2005-06-08	2014-04-01	The University Of North Carolina At Chapel Hill	Methods of facilitating neural cell survival using non-peptide and peptide BDNF neurotrophin mimetics
PT1904104E (pt)	2005-07-08	2013-11-21	Biogen Idec Inc	Anticorpos sp35 e suas utilizações
US8642040B2 (en)	2006-07-24	2014-02-04	Biogen Idec Ma Inc.	Methods for promoting myelination, neuronal survival and oligodendrocyte differentiation via administration of Sp35 or TrkA antagonists
AU2011253937B2 (en) *	2006-12-05	2012-09-27	The Royal Institution For The Advancement Of Learning/ Mcgill University	Methods of use of TRK receptor modulators
JP5576659B2 (ja) *	2006-12-05	2014-08-20	ザロイヤルインスティテューションフォージアドバンスメントオブラーニング／マギルユニバーシティ	Ｔｒｋレセプター調節因子の使用方法
AU2008311251B9 (en) *	2007-10-11	2014-04-17	Biogen Ma Inc.	Methods for treating pressure induced optic neuropathy, preventing neuronal degeneration and promoting neuronal cell, survival via administration of lingo-1 antagonists and TrkB agonists
EP2217697B1 (fr) *	2007-11-08	2015-06-10	Biogen MA Inc.	Utilisation des antagonistes de lingo-4 dans le traitement d'états mettant en jeu une démyélination
US8293713B2 (en) *	2008-04-04	2012-10-23	Mimetogen Pharmaceuticals, Inc.	Beta-turn peptidomimetic cyclic compounds for treating dry eye
EP2315779A2 (fr)	2008-07-09	2011-05-04	Biogen Idec MA Inc.	Compositions comprenant des anticorps anti-lingo ou leurs fragments
CA2752891C (fr)	2009-02-27	2018-08-21	Mimetogen Pharmaceuticals Inc.	Composes cycliques peptidomimetiques pour le traitement de la retinite pigmentaire
CN104761515B (zh)	2009-11-12	2018-03-09	特罗菲克斯制药股份有限公司	神经营养蛋白模拟化合物及其盐的晶型
US10273219B2 (en)	2009-11-12	2019-04-30	Pharmatrophix, Inc.	Crystalline forms of neurotrophin mimetic compounds and their salts
JP2015518829A (ja)	2012-05-14	2015-07-06	バイオジェン・エムエイ・インコーポレイテッドＢｉｏｇｅｎＭＡＩｎｃ．	運動ニューロンに関する状態の処置のためのｌｉｎｇｏ−２アンタゴニスト
ES2834125T3 (es) *	2012-06-22	2021-06-16	Mimetogen Pharmaceuticals Inc	Síntesis de compuestos cíclicos peptidomiméticos de giro beta
JP2016516044A (ja)	2013-03-15	2016-06-02	ファーマトロフィックス，インコーポレイテッド	非ペプチドｂｄｎｆニューロトロフィン模倣化合物
CN105189449A (zh)	2013-03-15	2015-12-23	特罗菲克斯制药股份有限公司	非肽bdnf神经营养蛋白模拟物
CN111732652A (zh)	2013-09-09	2020-10-02	卡尼姆盖德治疗学公司	免疫系统调节器
US10435467B2 (en)	2015-01-08	2019-10-08	Biogen Ma Inc.	LINGO-1 antagonists and uses for treatment of demyelinating disorders
AU2016229309B2 (en)	2015-03-06	2021-12-02	Canimguide Therapeutics Ab	Immune system modulators and compositions
EP4549450A2 (fr)	2015-07-09	2025-05-07	Mimetogen Pharmaceuticals, Inc.	Synthèse en phase de solution et cristallisation de sels cycliques peptidomimétiques à coude bêta
JPWO2022009992A1 (fr) *	2020-07-10	2022-01-13
WO2024031084A2 (fr) *	2022-08-05	2024-02-08	The Texas A&M University System	Compositions et procédés pour des peptides cyclisés liés à un colorant à usage médical
FR3148027A1 (fr) *	2023-04-24	2024-10-25	Peptinov	Composition vaccinale anti-ngf

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GB9402331D0 (en) *	1994-02-07	1994-03-30	Univ Mcgill	Nerve growth factor structural analogs and their uses

2001
- 2001-01-18 AT AT01942551T patent/ATE340571T1/de not_active IP Right Cessation
- 2001-01-18 AU AU2001228212A patent/AU2001228212A1/en not_active Abandoned
- 2001-01-18 EP EP01942551A patent/EP1265605B1/fr not_active Expired - Lifetime
- 2001-01-18 ES ES01942551T patent/ES2273849T3/es not_active Expired - Lifetime
- 2001-01-18 CA CA2397670A patent/CA2397670C/fr not_active Expired - Lifetime
- 2001-01-18 US US10/181,546 patent/US6881719B2/en not_active Expired - Lifetime
- 2001-01-18 DK DK01942551T patent/DK1265605T3/da active
- 2001-01-18 DE DE60123399T patent/DE60123399T2/de not_active Expired - Lifetime
- 2001-01-18 WO PCT/CA2001/000043 patent/WO2001052843A1/fr active IP Right Grant

Also Published As

Publication number	Publication date
WO2001052843A1 (fr)	2001-07-26
DE60123399T2 (de)	2007-08-23
DE60123399D1 (de)	2006-11-09
US6881719B2 (en)	2005-04-19
ATE340571T1 (de)	2006-10-15
EP1265605B1 (fr)	2006-09-27
AU2001228212A1 (en)	2001-07-31
CA2397670A1 (fr)	2001-07-26
CA2397670C (fr)	2010-06-08
US20030211982A1 (en)	2003-11-13
EP1265605A1 (fr)	2002-12-18
ES2273849T3 (es)	2007-05-16

Publication	Publication Date	Title
DK1265605T3 (da)	2007-02-12	Farmaceutiske sammensætninger omfattende peptidmimetisk, cyklisk beta-drejningsforbindelse
BRPI0411155A (pt)	2006-07-11	composto que se liga a e ativa o receptor de eritropoietina, composição farmacêutica e seu uso
Contreras et al.	1984	Antagonism of morphine-induced analgesia, tolerance and dependence by alpha-melanocyte-stimulating hormone.
EP1496935A4 (fr)	2006-06-07	Agonistes et antagonistes du recepteur de l'insuline et d'igf-1
DE60132017D1 (de)	2008-01-31	Neue benzazepine und ähnliche heterocyclische derivate,die als orexin rezeptor antagonisten geeignet sind
ATE480252T1 (de)	2010-09-15	Peptidantagonist von zonulin und dessen verwendung
YU42402A (sh)	2006-01-16	Jedinjenja karbamida koja imaju antagonističku aktivnost na muskarinski receptor
BR9911621A (pt)	2001-10-16	Bifenil sulfonamidas como antagonista duplos de receptor de angiotensina endotelina
DE60205234D1 (de)	2005-09-01	1,2,3,4-tetrahydroisochinolin-derivate als urotensin ii rezeptor-antagonisten
PT1274687E (pt)	2005-04-29	Derivados de 1,2,3,4-tetra-hidroisoquinolina
Cristofori-Armstrong et al.	2019	The modulation of acid-sensing ion channel 1 by PcTx1 is pH-, subtype-and species-dependent: Importance of interactions at the channel subunit interface and potential for engineering selective analogues
YU80902A (sh)	2005-11-28	Novi indolin-2-on derivati, njihovo dobijanje i farmaceuski oblici koji ih sadrže
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ATE227276T1 (de)	2002-11-15	Neue pyrimidinderivate
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Zaitseva et al.	2018	Prospects of a search for kappa-opioid receptor agonists with analgesic activity
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