DK1186667T3 - Kappegendeficient virusvektor af Paramyxoviridae - Google Patents
Kappegendeficient virusvektor af ParamyxoviridaeInfo
- Publication number
- DK1186667T3 DK1186667T3 DK00927807T DK00927807T DK1186667T3 DK 1186667 T3 DK1186667 T3 DK 1186667T3 DK 00927807 T DK00927807 T DK 00927807T DK 00927807 T DK00927807 T DK 00927807T DK 1186667 T3 DK1186667 T3 DK 1186667T3
- Authority
- DK
- Denmark
- Prior art keywords
- gene
- deficient
- virus
- successfully
- paramyxoviridae
- Prior art date
Links
- 230000002950 deficient Effects 0.000 title abstract 9
- 241000700605 Viruses Species 0.000 title abstract 7
- 241000711504 Paramyxoviridae Species 0.000 title abstract 2
- 239000013598 vector Substances 0.000 title abstract 2
- 101150034814 F gene Proteins 0.000 abstract 7
- 101150008820 HN gene Proteins 0.000 abstract 4
- 210000004027 cell Anatomy 0.000 abstract 4
- 210000002443 helper t lymphocyte Anatomy 0.000 abstract 3
- 239000002299 complementary DNA Substances 0.000 abstract 2
- 208000015181 infectious disease Diseases 0.000 abstract 2
- 230000002458 infectious effect Effects 0.000 abstract 2
- 239000002245 particle Substances 0.000 abstract 2
- 210000002845 virion Anatomy 0.000 abstract 2
- 230000003612 virological effect Effects 0.000 abstract 2
- 108010068327 4-hydroxyphenylpyruvate dioxygenase Proteins 0.000 abstract 1
- 241000711408 Murine respirovirus Species 0.000 abstract 1
- 238000001415 gene therapy Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5254—Virus avirulent or attenuated
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5256—Virus expressing foreign proteins
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/18011—Paramyxoviridae
- C12N2760/18811—Sendai virus
- C12N2760/18822—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/18011—Paramyxoviridae
- C12N2760/18811—Sendai virus
- C12N2760/18841—Use of virus, viral particle or viral elements as a vector
- C12N2760/18843—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/18011—Paramyxoviridae
- C12N2760/18811—Sendai virus
- C12N2760/18841—Use of virus, viral particle or viral elements as a vector
- C12N2760/18845—Special targeting system for viral vectors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/18011—Paramyxoviridae
- C12N2760/18811—Sendai virus
- C12N2760/18861—Methods of inactivation or attenuation
- C12N2760/18862—Methods of inactivation or attenuation by genetic engineering
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/20011—Rhabdoviridae
- C12N2760/20211—Vesiculovirus, e.g. vesicular stomatitis Indiana virus
- C12N2760/20222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2800/00—Nucleic acids vectors
- C12N2800/30—Vector systems comprising sequences for excision in presence of a recombinase, e.g. loxP or FRT
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2810/00—Vectors comprising a targeting moiety
- C12N2810/50—Vectors comprising as targeting moiety peptide derived from defined protein
- C12N2810/60—Vectors comprising as targeting moiety peptide derived from defined protein from viruses
- C12N2810/6072—Vectors comprising as targeting moiety peptide derived from defined protein from viruses negative strand RNA viruses
- C12N2810/6081—Vectors comprising as targeting moiety peptide derived from defined protein from viruses negative strand RNA viruses rhabdoviridae, e.g. VSV
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Virology (AREA)
- Microbiology (AREA)
- Plant Pathology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Immunology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP20073999 | 1999-05-18 | ||
| PCT/JP2000/003195 WO2000070070A1 (fr) | 1999-05-18 | 2000-05-18 | Vecteur de virus paramyxoviridae defectueux dans un gene enveloppe |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1186667T3 true DK1186667T3 (da) | 2007-10-22 |
Family
ID=16429375
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK00927807T DK1186667T3 (da) | 1999-05-18 | 2000-05-18 | Kappegendeficient virusvektor af Paramyxoviridae |
Country Status (12)
| Country | Link |
|---|---|
| EP (1) | EP1186667B1 (da) |
| JP (2) | JP3602058B2 (da) |
| KR (2) | KR20070058607A (da) |
| CN (1) | CN1330767C (da) |
| AT (1) | ATE367445T1 (da) |
| AU (1) | AU4614600A (da) |
| CA (1) | CA2368948C (da) |
| DE (1) | DE60035589T2 (da) |
| DK (1) | DK1186667T3 (da) |
| ES (1) | ES2288473T3 (da) |
| HK (1) | HK1044352A1 (da) |
| WO (1) | WO2000070070A1 (da) |
Families Citing this family (60)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3883213B2 (ja) * | 1998-07-03 | 2007-02-21 | 株式会社ディナベック研究所 | 神経細胞用（−）鎖ｒｎａウィルスベクター |
| US7241617B2 (en) | 1998-07-03 | 2007-07-10 | Dnavec Research, Inc. | Sendai viral vectors comprising foreign genes inserted between the R1 and R2 Loci |
| WO2003025570A1 (en) * | 2001-09-18 | 2003-03-27 | Dnavec Research Inc. | Method of examining (-) strand rna virus vector having lowered ability to form grains and method of constructing the same |
| US7226786B2 (en) | 1999-05-18 | 2007-06-05 | Dnavec Research Inc. | Envelope gene-deficient Paramyxovirus vector |
| CA2397903A1 (en) * | 2000-01-19 | 2001-07-26 | Dnavec Research Inc. | Use of paramyxovirus vector for gene transfer into blood vessel |
| CN1248740C (zh) | 2000-03-30 | 2006-04-05 | 株式会社载体研究所 | 使用仙台病毒载体的aids病毒疫苗 |
| JP2002142770A (ja) | 2000-11-08 | 2002-05-21 | Dnavec Research Inc | 循環系への遺伝子送達用パラミクソウイルスベクター |
| WO2002042481A1 (fr) | 2000-11-27 | 2002-05-30 | Dnavec Research Inc. | Vecteur paramyxovirus codant pour un gene d'angiogenese et son utilisation |
| KR100964413B1 (ko) | 2001-01-19 | 2010-06-15 | 비로노바티브 비.브이. | 감응성 포유류에서 호흡계 질환을 유발하는 바이러스 |
| US8715922B2 (en) | 2001-01-19 | 2014-05-06 | ViroNovative | Virus causing respiratory tract illness in susceptible mammals |
| FR2826010B1 (fr) * | 2001-06-14 | 2005-02-25 | Mahmood Salman Al | Oligonucleotides antisens capables d'inhiber la formation des tubes capillaires par les cellules endotheliales |
| EP2327418A1 (en) | 2002-02-21 | 2011-06-01 | MedImmune, LLC | Recombinant parainfluenza virus expression systems and vaccines comprising heterologous antigens derived from other viruses |
| CN101054419A (zh) * | 2002-04-30 | 2007-10-17 | 株式会社载体研究所 | 具有修饰的蛋白酶依赖向性的载体 |
| KR100587388B1 (ko) * | 2003-02-14 | 2006-06-08 | 주식회사 효성 | 고강도 폴리비닐알코올 섬유의 제조방법 및 그로부터수득되는 고강도 폴리비닐알코올 섬유 |
| KR101187955B1 (ko) * | 2003-04-25 | 2012-10-08 | 비로노바티브 비브이 | 메타뉴모바이러스 유래 이종 항원을 포함하는 재조합파라인플루엔자 바이러스 발현 시스템 및 백신 |
| EP1636371B1 (en) * | 2003-06-13 | 2012-04-25 | Apath, LLC | Negative strand rna virus replicon |
| WO2005042737A1 (ja) | 2003-11-04 | 2005-05-12 | Dnavec Research Inc. | 遺伝子導入された樹状細胞の製造方法 |
| WO2005067981A1 (ja) | 2004-01-13 | 2005-07-28 | Dnavec Research Inc. | 免疫刺激性サイトカインをコードするマイナス鎖rnaウイルスベクターを用いる腫瘍の遺伝子治療 |
| EP1717317A4 (en) * | 2004-01-22 | 2009-02-11 | Dnavec Research Inc | METHOD OF GENERATING VIRAL NEGATIVE STRAND RNA VECTORS USING A HYBRID PROMOTER COMPRISING THE CYTOMEGALOVIRUS ENHANCER AND THE BETA ACTIN PROMOTER FROM CHICKEN |
| WO2005071085A1 (ja) * | 2004-01-22 | 2005-08-04 | Dnavec Research Inc. | ウイルスベクターの製造方法 |
| US20080038234A1 (en) * | 2004-03-23 | 2008-02-14 | Shuji Hayashi | Bone Marrow-Related Cells Associated With Tissue Maintenance And/Or Repair |
| CA2571849A1 (en) * | 2004-06-24 | 2006-01-05 | Dnavec Research Inc. | Anticancer agent containing dendritic cell having rna virus transferred thereinto |
| JP2008105946A (ja) * | 2005-02-08 | 2008-05-08 | Dnavec Corp | 遺伝子導入造血細胞から血液細胞を再構築させる方法 |
| DE102005015005A1 (de) * | 2005-04-01 | 2006-10-05 | Qiagen Gmbh | Verfahren zur Behandlung einer Biomoleküle enthaltenden Probe |
| CA2612168A1 (en) | 2005-06-14 | 2006-12-21 | Dnavec Corporation | Methods for producing antibodies |
| WO2006137517A1 (ja) * | 2005-06-24 | 2006-12-28 | Dnavec Corporation | 幼少個体への遺伝子導入用ベクター |
| DK1950307T3 (da) | 2005-10-28 | 2016-02-15 | Id Pharma Co Ltd | Genoverførsel til luftvejsepitelstamcelle ved anvendelse af en lentivirusvektor, som er pseudo-typificeret med RNA-virus-spike-protein |
| WO2007061141A1 (ja) * | 2005-11-24 | 2007-05-31 | Genomidea, Inc. | 改変パラミクソウイルスおよびその作製方法 |
| CA2636600A1 (en) * | 2006-01-17 | 2007-07-26 | Dnavec Corporation | Novel protein expression system |
| US20090246170A1 (en) | 2006-05-31 | 2009-10-01 | Dnavec Corporation | Therapeutic Agent For Alzheimer's Disease |
| WO2008007581A1 (fr) | 2006-07-13 | 2008-01-17 | Dnavec Corporation | Vecteur de virus paramyxoviridae non répliquant |
| CN101646768A (zh) | 2007-02-07 | 2010-02-10 | 生物载体株式会社 | 减毒负链rna病毒 |
| WO2008129971A1 (ja) * | 2007-04-13 | 2008-10-30 | National Institute Of Advanced Industrial Science And Technology | 改良された持続感染型センダイウイルスベクター |
| WO2008136438A1 (ja) | 2007-04-27 | 2008-11-13 | Kyushu University, National University Corporation | 遺伝子治療用ウイルスベクター |
| DK2322611T3 (da) | 2008-07-16 | 2016-09-05 | Ip Pharma Co Ltd | Fremgangsmåde til fremstilling af reprogrammeret celle under anvendelse af chromosomalt ikke-integreret virusvektor |
| EP2363472B1 (en) | 2008-10-31 | 2014-12-10 | Dnavec Corporation | Method for enhancing expression of recombinant protein |
| US8951801B2 (en) | 2009-02-27 | 2015-02-10 | Kyoto University | Method for making IPS cells |
| CA2770412C (en) | 2009-08-07 | 2018-09-11 | Kyoto University | Method of efficiently establishing induced pluripotent stem cells |
| JP5773393B2 (ja) | 2009-09-24 | 2015-09-02 | 国立大学法人京都大学 | 効率的な人工多能性幹細胞の樹立方法 |
| WO2011052771A1 (ja) * | 2009-11-02 | 2011-05-05 | 国立大学法人三重大学 | パラミクソウイルスベクターを用いた経鼻噴霧型結核ワクチン |
| WO2011083881A1 (ja) | 2010-01-08 | 2011-07-14 | 国立大学法人京都大学 | タウオパチー治療用ワクチン |
| US9005967B2 (en) | 2010-01-22 | 2015-04-14 | Kyoto University | Myc variants improve induced pluripotent stem cell generation efficiency |
| CA2796599A1 (en) | 2010-04-16 | 2011-10-20 | Keio University | Method for producing induced pluripotent stem cells |
| WO2012029770A1 (ja) | 2010-08-30 | 2012-03-08 | ディナベック株式会社 | 多能性幹細胞を誘導するための組成物およびその使用 |
| JP5794588B2 (ja) | 2010-09-14 | 2015-10-14 | 国立大学法人京都大学 | 効率的な人工多能性幹細胞の樹立方法 |
| US20130302367A1 (en) | 2010-10-22 | 2013-11-14 | Hisatoshi Shida | Virus vector for prime/boost vaccines, which comprises vaccinia virus vector and sendai virus vector |
| EP2647698A4 (en) | 2010-12-03 | 2015-10-07 | Univ Kyoto | PROCESS FOR PRODUCING EOSINOPHILES FROM PLURIPOTENT STEM CELLS |
| EP2647699B1 (en) | 2010-12-03 | 2020-04-01 | Kyoto University | Efficient method for establishing induced pluripotent stem cells |
| US8911975B2 (en) | 2011-02-08 | 2014-12-16 | Mie University | Method for producing virus vector for gene transfer |
| EP3636755A1 (en) * | 2012-12-26 | 2020-04-15 | BioComo Inc. | Vaccine prepared utilizing human parainfluenza virus type 2 vector |
| AU2014324233B2 (en) | 2013-09-24 | 2020-07-23 | Id Pharma Co., Ltd. | Method for improving efficiency of inducing pluripotent stem cell |
| US20180339038A1 (en) * | 2015-06-12 | 2018-11-29 | Mie University | Human parainfluenza virus type 2 vector and vaccine |
| US11103574B2 (en) | 2016-11-17 | 2021-08-31 | Japan, as represented by the Director-General of National Institute of Infectious Disease | Infectious disease vaccine using non-infectious paramyxovirus particle |
| CN111479920A (zh) | 2017-07-21 | 2020-07-31 | 株式会社爱医隆集团 | 用于修饰靶序列的多核苷酸及其用途 |
| EP3744847A4 (en) | 2018-01-22 | 2021-12-08 | Japan as Represented by The Director-General of National Institute of Infectious Diseases | SELECTIVE VACCINE ANTIGEN INDUCING CD8-POSITIVE T-LYMPHOCYTES |
| KR102764120B1 (ko) | 2019-12-31 | 2025-02-06 | 엘릭서젠 쎄라퓨틱스, 인크. | 핵산 및 단백질의 세포 및 조직으로의 온도-기반 일시적 전달 |
| US20230220025A1 (en) | 2020-09-04 | 2023-07-13 | Heartseed Inc. | Quality Improving Agent for IPS Cells, Method of Producing IPS Cells, IPS Cells, and Composition for Producing IPS Cells |
| JPWO2022138964A1 (da) | 2020-12-25 | 2022-06-30 | ||
| JP2022104813A (ja) | 2020-12-29 | 2022-07-11 | アイ ピース，インコーポレイテッド | リプログラミング因子を導入された細胞の培養方法 |
| EP4524249A1 (en) | 2022-04-25 | 2025-03-19 | Tokiwa-bio Inc. | Rna virus-derived chimeric envelope protein and rna virus vector having same |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5512421A (en) * | 1991-02-19 | 1996-04-30 | The Regents Of The University Of California | Generation, concentration and efficient transfer of VSV-G pseudotyped retroviral vectors |
| KR100552387B1 (ko) * | 1995-10-31 | 2006-04-21 | 가부시끼가이샤 디나벡 겡뀨쇼 | 자율 복제 능력을 갖는 (-)쇄 rna 바이러스 벡터 |
| KR100525687B1 (ko) * | 1995-11-01 | 2005-11-25 | 가부시끼가이샤 디나벡 겡뀨쇼 | 재조합체 센다이바이러스 |
| AU7335396A (en) * | 1995-11-01 | 1997-05-22 | Dnavec Research Inc. | Membrane-fusible liposome with the use of recombinant sendai virus |
| WO2000070055A1 (fr) * | 1999-05-18 | 2000-11-23 | Dnavec Research Inc. | Ribonucleoproteine derivee d'un paramyxovirus |
-
2000
- 2000-05-18 EP EP00927807A patent/EP1186667B1/en not_active Expired - Lifetime
- 2000-05-18 CN CNB008056730A patent/CN1330767C/zh not_active Expired - Lifetime
- 2000-05-18 WO PCT/JP2000/003195 patent/WO2000070070A1/ja active IP Right Grant
- 2000-05-18 DE DE60035589T patent/DE60035589T2/de not_active Expired - Lifetime
- 2000-05-18 KR KR1020077008323A patent/KR20070058607A/ko not_active Ceased
- 2000-05-18 AU AU46146/00A patent/AU4614600A/en not_active Abandoned
- 2000-05-18 ES ES00927807T patent/ES2288473T3/es not_active Expired - Lifetime
- 2000-05-18 KR KR1020017012612A patent/KR100739938B1/ko not_active Expired - Fee Related
- 2000-05-18 CA CA2368948A patent/CA2368948C/en not_active Expired - Fee Related
- 2000-05-18 DK DK00927807T patent/DK1186667T3/da active
- 2000-05-18 AT AT00927807T patent/ATE367445T1/de active
- 2000-05-18 JP JP2000618476A patent/JP3602058B2/ja not_active Expired - Lifetime
-
2002
- 2002-08-15 HK HK02105976A patent/HK1044352A1/xx not_active IP Right Cessation
-
2004
- 2004-08-02 JP JP2004253541A patent/JP2004329222A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| EP1186667A4 (en) | 2004-06-30 |
| AU4614600A (en) | 2000-12-05 |
| ATE367445T1 (de) | 2007-08-15 |
| HK1044352A1 (en) | 2002-10-18 |
| KR20020014786A (ko) | 2002-02-25 |
| DE60035589D1 (de) | 2007-08-30 |
| KR100739938B1 (ko) | 2007-07-16 |
| CA2368948A1 (en) | 2000-11-23 |
| CN1355851A (zh) | 2002-06-26 |
| EP1186667B1 (en) | 2007-07-18 |
| WO2000070070A1 (fr) | 2000-11-23 |
| EP1186667A1 (en) | 2002-03-13 |
| JP3602058B2 (ja) | 2004-12-15 |
| CN1330767C (zh) | 2007-08-08 |
| ES2288473T3 (es) | 2008-01-16 |
| KR20070058607A (ko) | 2007-06-08 |
| JP2004329222A (ja) | 2004-11-25 |
| CA2368948C (en) | 2013-12-24 |
| DE60035589T2 (de) | 2008-04-17 |
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