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DK1152753T3 - Kombinationer af formoterol og fluticasonpropionat til astma - Google Patents

Kombinationer af formoterol og fluticasonpropionat til astma

Info

Publication number
DK1152753T3
DK1152753T3 DK00907572T DK00907572T DK1152753T3 DK 1152753 T3 DK1152753 T3 DK 1152753T3 DK 00907572 T DK00907572 T DK 00907572T DK 00907572 T DK00907572 T DK 00907572T DK 1152753 T3 DK1152753 T3 DK 1152753T3
Authority
DK
Denmark
Prior art keywords
formoterol
asthma
combinations
fluticasone propionate
fluticasone
Prior art date
Application number
DK00907572T
Other languages
Danish (da)
English (en)
Inventor
Jeremy Guy Clarke
Henry Luke Danahay
Ian Francis Hassan
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10848051&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK1152753(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis Ag filed Critical Novartis Ag
Application granted granted Critical
Publication of DK1152753T3 publication Critical patent/DK1152753T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/165Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/166Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the carbon of a carboxamide group directly attached to the aromatic ring, e.g. procainamide, procarbazine, metoclopramide, labetalol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/165Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/008Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0078Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions

Landscapes

  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Otolaryngology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DK00907572T 1999-02-18 2000-02-16 Kombinationer af formoterol og fluticasonpropionat til astma DK1152753T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9903759.0A GB9903759D0 (en) 1999-02-18 1999-02-18 Organic compounds
PCT/EP2000/001270 WO2000048587A1 (fr) 1999-02-18 2000-02-16 Combinaisons de formoterol et de fluticasone propionate pour le traitement de l'asthme

Publications (1)

Publication Number Publication Date
DK1152753T3 true DK1152753T3 (da) 2004-08-16

Family

ID=10848051

Family Applications (1)

Application Number Title Priority Date Filing Date
DK00907572T DK1152753T3 (da) 1999-02-18 2000-02-16 Kombinationer af formoterol og fluticasonpropionat til astma

Country Status (32)

Country Link
US (4) US20020103260A1 (fr)
EP (1) EP1152753B1 (fr)
JP (1) JP2002537249A (fr)
KR (2) KR20010102205A (fr)
CN (1) CN1339965A (fr)
AR (1) AR022609A1 (fr)
AT (1) ATE266393T1 (fr)
AU (1) AU758999B2 (fr)
BR (1) BR0008276A (fr)
CA (1) CA2368537A1 (fr)
CO (1) CO5140098A1 (fr)
CZ (1) CZ20012976A3 (fr)
DE (1) DE60010662T2 (fr)
DK (1) DK1152753T3 (fr)
ES (1) ES2220411T3 (fr)
GB (1) GB9903759D0 (fr)
HK (1) HK1042429A1 (fr)
HU (1) HUP0200852A3 (fr)
ID (1) ID29437A (fr)
IL (1) IL144061A (fr)
MY (1) MY126768A (fr)
NO (1) NO20013987L (fr)
NZ (1) NZ513526A (fr)
PE (1) PE20001545A1 (fr)
PL (1) PL349856A1 (fr)
PT (1) PT1152753E (fr)
RU (1) RU2249454C2 (fr)
SK (1) SK11842001A3 (fr)
TR (1) TR200102110T2 (fr)
TW (1) TWI229601B (fr)
WO (1) WO2000048587A1 (fr)
ZA (1) ZA200105391B (fr)

Families Citing this family (44)

* Cited by examiner, † Cited by third party
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GB9616237D0 (en) 1996-08-01 1996-09-11 Norton Healthcare Ltd Aerosol formulations
FR2798290B1 (fr) 1999-09-11 2003-09-12 Glaxo Group Ltd Formulation pharmaceutique de propionate de fluticasone
GB2392164B (en) * 1999-09-11 2004-04-07 Glaxo Group Ltd Pharmaceutical formulation of fluticasone propionate
GB2388843B (en) * 1999-09-11 2004-03-03 Glaxo Group Ltd A metered dose inhaler containing a pharmaceutical formulation of fluticasone propionate
AU2001252350A1 (en) * 2000-04-13 2001-10-30 Innovata Biomed Limited Medicaments for treating respiratory disorders comprising formoterol and fluticasone
GB0009591D0 (en) * 2000-04-18 2000-06-07 Glaxo Group Ltd Medical combinations
GB0012260D0 (en) 2000-05-19 2000-07-12 Astrazeneca Ab Novel composition
US6759398B2 (en) * 2000-08-05 2004-07-06 Smithkline Beecham Corporation Anti-inflammatory androstane derivative
FI20002216A0 (fi) 2000-10-06 2000-10-06 Orion Yhtymae Oyj Yhdistelmäpartikkelit astman hoitoon
FI20002215A0 (fi) 2000-10-06 2000-10-06 Orion Yhtymae Oyj Yhdistelmäpartikkelit
BR0207062A (pt) * 2001-02-06 2004-10-05 Innovata Biomed Ltd Composição farmacêutica bimodal, inalador para pó seco, método de aplicação de uma quantidade terapeuticamente eficaz de um ingrediente ativo substancialmente fino aos pulmões de um paciente, método de tratamento de um distúrbio respiratório, método de tratamento de doença pulmonar obstrutiva crÈnica (copd), uso de um agente antiinflamatório, uso de um broncodilatador, uso de uma mistura de um agente antiinflamatório e de um broncodilatador, e, processo para a fabricação de uma composição farmacêutica bimodal
GB0106031D0 (en) * 2001-03-12 2001-05-02 Glaxo Group Ltd Use
DK1372608T3 (da) * 2001-03-30 2007-12-27 Jagotec Ag Medicinske aerosolformuleringer
US6667344B2 (en) 2001-04-17 2003-12-23 Dey, L.P. Bronchodilating compositions and methods
US20030055026A1 (en) 2001-04-17 2003-03-20 Dey L.P. Formoterol/steroid bronchodilating compositions and methods of use thereof
US7931022B2 (en) 2001-10-19 2011-04-26 Respirks, Inc. Method and apparatus for dispensing inhalator medicament
JP2005523268A (ja) 2002-02-04 2005-08-04 グラクソ グループ リミテッド グルココルチコイドおよびβ2−アドレナリン受容体アゴニストを含む吸入用製剤
EP1757281A3 (fr) * 2002-02-04 2009-07-15 Glaxo Group Limited Formulation pour inhalation comprenant un glucocorticoïde et un agoniste de 2-adrénorécepteur béta
GB2389530B (en) 2002-06-14 2007-01-10 Cipla Ltd Pharmaceutical compositions
US20050158248A1 (en) * 2002-08-21 2005-07-21 Xian-Ming Zeng Method of preparing dry powder inhalation compositions
EA007377B1 (ru) 2002-08-21 2006-10-27 Нортон Хелткэа Лтд. Композиции для ингаляции
JP4744876B2 (ja) * 2002-08-21 2011-08-10 ノートン・ヘルスケアー リミテッド 乾燥粉末吸入組成物の製造方法
GB0219511D0 (en) * 2002-08-21 2002-10-02 Norton Healthcare Ltd Method of preparing dry powder inhalation compositions
WO2004028545A1 (fr) * 2002-09-25 2004-04-08 Astrazeneca Ab Combinaison d'un agoniste $g(b)2 a action prolongee et d'un glucocorticosteroide dans le traitement de maladies fibrotiques
SE527069C2 (sv) * 2003-06-19 2005-12-13 Mederio Ag Förfarande och anordning för administrering av läkemedelspulver
SE526850C2 (sv) * 2003-06-19 2005-11-08 Microdrug Ag Farmaceutisk kombinerad torr pulverdos separerade på gemensam dosbädd
SE527200C2 (sv) * 2003-06-19 2006-01-17 Microdrug Ag Inhalatoranordning samt kombinerade doser av formaterol och fluticason
SE526509C2 (sv) * 2003-06-19 2005-09-27 Microdrug Ag Kombinerade doser av formoterol och budesonid separerade på en gemensam dosbädd
SE527189C2 (sv) * 2003-06-19 2006-01-17 Microdrug Ag Inhalatoranordning samt kombinerade doser för formaterol och ett antikolinergiskt medel
TWI359675B (en) 2003-07-10 2012-03-11 Dey L P Bronchodilating β-agonist compositions
GB0323684D0 (en) * 2003-10-09 2003-11-12 Jagotec Ag Improvements in or relating to organic compounds
GB0323685D0 (en) * 2003-10-09 2003-11-12 Jagotec Ag Improvements in or relating to organic compounds
RU2431501C2 (ru) * 2005-07-14 2011-10-20 Липотера, Инк. Липолитические составы с пролонгированным высвобождением для локального лечения отложения жировых тканей
GB0617171D0 (en) * 2006-08-31 2006-10-11 Generics Uk Ltd Novel compositions and methods
WO2008137446A1 (fr) * 2007-05-03 2008-11-13 Trustees Of Boston University Procédés et compositions pour le traitement des maladies respiratoires
ES2774367T3 (es) * 2009-05-29 2020-07-20 Pearl Therapeutics Inc Composiciones para el suministro respiratorio de agentes activos y métodos y sistemas asociados
US8815258B2 (en) 2009-05-29 2014-08-26 Pearl Therapeutics, Inc. Compositions, methods and systems for respiratory delivery of two or more active agents
GB0918150D0 (en) * 2009-10-16 2009-12-02 Jagotec Ag Improved formulations
GB0918149D0 (en) 2009-10-16 2009-12-02 Jagotec Ag Improved medicinal aerosol formulation
WO2011093811A2 (fr) * 2010-01-29 2011-08-04 Mahmut Bilgic Préparations pharmaceutiques comprenant du formotérol et du fluticasone
AU2011315315B2 (en) * 2010-10-12 2016-08-18 Cipla Limited Pharmaceutical composition
CA2835927A1 (fr) * 2011-05-17 2012-11-22 Pearl Therapeutics, Inc. Compositions, procedes et systemes d'administration par voie respiratoire d'au moins deux agents actifs
KR20150002774A (ko) 2012-04-11 2015-01-07 시플라 리미티드 아르포르모테롤 및 플루티카손 푸로에이트를 포함하는 약학 조성물
US20140275517A1 (en) 2013-03-15 2014-09-18 Pearl Therapeutics, Inc. Methods and systems for conditioning of particulate crystalline materials

Family Cites Families (8)

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Publication number Priority date Publication date Assignee Title
IL95590A (en) * 1989-09-08 1996-06-18 Glaxo Group Ltd Medicinal preparations containing Salmetrol and Pluticasone Propionate
SE9302777D0 (sv) * 1993-08-27 1993-08-27 Astra Ab Process for conditioning substances
US5658549A (en) * 1991-12-12 1997-08-19 Glaxo Group Limited Aerosol formulations containing propellant 134a and fluticasone propionate
CA2123909C (fr) * 1991-12-18 2002-10-01 Christer Carl Gustav Carling Nouvelle combinaison de formoterol et de budesonide
GB9426252D0 (en) * 1994-12-24 1995-02-22 Glaxo Group Ltd Pharmaceutical composition
SE9700135D0 (sv) * 1997-01-20 1997-01-20 Astra Ab New formulation
EP1014943B1 (fr) * 1997-02-05 2002-06-19 Jago Research Ag Formulations medicales pour aerosols
NZ337443A (en) * 1997-03-20 2001-04-27 Schering Corp Preparation of powder agglomerates for the production of agglomerated dosage forms suitable for oral and/or nasal inhalation especially for pharmaceuticals of particle size less than 10 microns forming an inter particle bridge between agglomerates

Also Published As

Publication number Publication date
CO5140098A1 (es) 2002-03-22
EP1152753A1 (fr) 2001-11-14
CA2368537A1 (fr) 2000-08-24
KR20070104955A (ko) 2007-10-29
SK11842001A3 (sk) 2001-12-03
HK1042429A1 (en) 2002-08-16
DE60010662T2 (de) 2005-05-19
NO20013987D0 (no) 2001-08-16
BR0008276A (pt) 2001-11-06
ES2220411T3 (es) 2004-12-16
WO2000048587A1 (fr) 2000-08-24
NZ513526A (en) 2004-01-30
PL349856A1 (en) 2002-09-23
ATE266393T1 (de) 2004-05-15
AR022609A1 (es) 2002-09-04
US20020103260A1 (en) 2002-08-01
NO20013987L (no) 2001-08-16
JP2002537249A (ja) 2002-11-05
GB9903759D0 (en) 1999-04-14
CZ20012976A3 (cs) 2001-11-14
CN1339965A (zh) 2002-03-13
EP1152753B1 (fr) 2004-05-12
PE20001545A1 (es) 2001-01-29
TR200102110T2 (tr) 2001-10-22
IL144061A0 (en) 2002-04-21
HUP0200852A3 (en) 2004-04-28
US20040101487A1 (en) 2004-05-27
US20100034890A1 (en) 2010-02-11
IL144061A (en) 2005-12-18
US20050287079A1 (en) 2005-12-29
KR20010102205A (ko) 2001-11-15
ID29437A (id) 2001-08-30
AU758999B2 (en) 2003-04-03
RU2249454C2 (ru) 2005-04-10
HUP0200852A2 (en) 2002-08-28
PT1152753E (pt) 2004-09-30
AU2911500A (en) 2000-09-04
ZA200105391B (en) 2002-06-21
DE60010662D1 (de) 2004-06-17
MY126768A (en) 2006-10-31
TWI229601B (en) 2005-03-21

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