DK1053018T3 - Administration af immunogene molekyler via HBsAg-partikler - Google Patents

Administration af immunogene molekyler via HBsAg-partikler

Info

Publication number: DK1053018T3
Authority: DK; Denmark
Prior art keywords: hbsag particles; administration; particles; molecules via; immunogenic molecules
Prior art date: 1998-02-03

Application number

DK99902800T

Other languages

Danish (da)

English (en)

Inventor

Yechezkel Barenholz

Jorg Reimann

Dvorah Diminsky

Reinhold Schirmbeck

Original Assignee

Yissum Res Dev Co

Reimann Joerg

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-02-03

Filing date

1999-01-29

Publication date

2005-08-15

1999-01-29 Application filed by Yissum Res Dev Co, Reimann Joerg filed Critical Yissum Res Dev Co

2005-08-15 Application granted granted Critical

2005-08-15 Publication of DK1053018T3 publication Critical patent/DK1053018T3/da

Links

239000002245 particle Substances 0.000 title abstract 5
230000002163 immunogen Effects 0.000 title 1
108090000765 processed proteins & peptides Proteins 0.000 abstract 2
230000004044 response Effects 0.000 abstract 2
102000004127 Cytokines Human genes 0.000 abstract 1
108090000695 Cytokines Proteins 0.000 abstract 1
230000000890 antigenic effect Effects 0.000 abstract 1
238000005538 encapsulation Methods 0.000 abstract 1
230000000763 evoking effect Effects 0.000 abstract 1
230000028993 immune response Effects 0.000 abstract 1
230000003308 immunostimulating effect Effects 0.000 abstract 1
238000000034 method Methods 0.000 abstract 1
239000000203 mixture Substances 0.000 abstract 1
102000004196 processed proteins & peptides Human genes 0.000 abstract 1
230000004936 stimulating effect Effects 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/21—Retroviridae, e.g. equine infectious anemia virus
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/29—Hepatitis virus
- A61K39/292—Serum hepatitis virus, hepatitis B virus, e.g. Australia antigen
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5256—Virus expressing foreign proteins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5258—Virus-like particles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55522—Cytokines; Lymphokines; Interferons
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55555—Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55561—CpG containing adjuvants; Oligonucleotide containing adjuvants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2730/00—Reverse transcribing DNA viruses
- C12N2730/00011—Details
- C12N2730/10011—Hepadnaviridae
- C12N2730/10111—Orthohepadnavirus, e.g. hepatitis B virus
- C12N2730/10134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/16011—Human Immunodeficiency Virus, HIV
- C12N2740/16111—Human Immunodeficiency Virus, HIV concerning HIV env
- C12N2740/16134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Immunology (AREA)
Virology (AREA)
Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Microbiology (AREA)
Mycology (AREA)
Epidemiology (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
Bioinformatics & Cheminformatics (AREA)
Communicable Diseases (AREA)
Organic Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Hematology (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Peptides Or Proteins (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicinal Preparation (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

DK99902800T 1998-02-03 1999-01-29 Administration af immunogene molekyler via HBsAg-partikler DK1053018T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US7347698P	1998-02-03	1998-02-03
PCT/IL1999/000060 WO1999039736A2 (fr)	1998-02-03	1999-01-29	APPORT DE MOLECULES IMMUNOGENES VIA DES PARTICULES DE HBsAg

Publications (1)

Publication Number	Publication Date
DK1053018T3 true DK1053018T3 (da)	2005-08-15

Family

ID=22113916

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK99902800T DK1053018T3 (da)	1998-02-03	1999-01-29	Administration af immunogene molekyler via HBsAg-partikler

Country Status (9)

Country	Link
EP (1)	EP1053018B1 (fr)
JP (1)	JP4480267B2 (fr)
AT (1)	ATE300312T1 (fr)
AU (1)	AU755957B2 (fr)
CA (1)	CA2319599C (fr)
DE (1)	DE69926342T2 (fr)
DK (1)	DK1053018T3 (fr)
ES (1)	ES2242376T3 (fr)
WO (1)	WO1999039736A2 (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AUPQ912000A0 (en) *	2000-07-31	2000-08-24	Crown In The Right Of The Queensland Department Of Health, The	Improved virus like particles
DE10106235A1 (de) *	2001-02-10	2002-08-22	Bosch Gmbh Robert	Wischarm
CN1812766A (zh)	2003-04-25	2006-08-02	宾州研究基金会	用于全身传递使生长停滞的、衍生于脂质的生物活性化合物的方法和系统
CU23405A1 (es) *	2003-10-20	2009-08-04	Ct Ingenieria Genetica Biotech	Composiciones farmacéuticas para uso terapéutico
US9603921B2 (en)	2004-10-27	2017-03-28	Janssen Vaccines Ag	Virosome particles comprising antigens from influenza virus and hepatitis b virus
JP2009120532A (ja) *	2007-11-14	2009-06-04	Osaka Univ	糖及び糖鎖認識機構を利用する物質送達用及びバイオイメージング用バイオナノカプセル

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5039522A (en) *	1988-01-29	1991-08-13	New York Blood Center, Inc.	Immunogens containing peptides with an attached hydrophobic tail for adsorption to hepatitis B virus surface antigen
JP2001526688A (ja) *	1997-05-19	2001-12-18	メルクエンドカンパニーインコーポレーテッド	オリゴヌクレオチドアジュバント

1999
- 1999-01-29 ES ES99902800T patent/ES2242376T3/es not_active Expired - Lifetime
- 1999-01-29 EP EP99902800A patent/EP1053018B1/fr not_active Expired - Lifetime
- 1999-01-29 AT AT99902800T patent/ATE300312T1/de not_active IP Right Cessation
- 1999-01-29 CA CA2319599A patent/CA2319599C/fr not_active Expired - Fee Related
- 1999-01-29 AU AU22973/99A patent/AU755957B2/en not_active Ceased
- 1999-01-29 DE DE69926342T patent/DE69926342T2/de not_active Expired - Lifetime
- 1999-01-29 JP JP2000530233A patent/JP4480267B2/ja not_active Expired - Fee Related
- 1999-01-29 DK DK99902800T patent/DK1053018T3/da active
- 1999-01-29 WO PCT/IL1999/000060 patent/WO1999039736A2/fr active IP Right Grant

Also Published As

Publication number	Publication date
AU755957B2 (en)	2003-01-02
JP4480267B2 (ja)	2010-06-16
AU2297399A (en)	1999-08-23
JP2002502828A (ja)	2002-01-29
EP1053018B1 (fr)	2005-07-27
ATE300312T1 (de)	2005-08-15
DE69926342T2 (de)	2006-01-12
EP1053018A2 (fr)	2000-11-22
CA2319599A1 (fr)	1999-08-12
WO1999039736A3 (fr)	1999-09-23
DE69926342D1 (de)	2005-09-01
WO1999039736A2 (fr)	1999-08-12
CA2319599C (fr)	2011-04-19
ES2242376T3 (es)	2005-11-01

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DE69936386D1 (de)	2007-08-09	Sprühgetrocknete proteinformulierungen
ATE377076T1 (de)	2007-11-15	Humanes cytokin als ligand des zalpha rezeptors und dessen verwendungen
CA2182303A1 (fr)	1996-06-06	Procede de preparation d'un vecteur viral par recombinaison homologue intermoleculaire
ATE454901T1 (de)	2010-01-15	Verfahren zur erhaltung zellimmuneantworten gegen proteinen
DK1459766T3 (da)	2008-10-13	Adjuvanssammensætninger til forstærkning af immunresponser på polynukleotidbaserede vacciner
DE69417252D1 (de)	1999-04-22	Verbesserte immunogene zusammensetzung gegen mensliches gastrin 17
NZ331651A (en)	2000-01-28	BSW17 peptide immunogens for vaccination against and treatment of allergy
CA2231603A1 (fr)	1997-04-24	Interleukine-15 du poulet et ses utilisations
BR9811475A (pt)	2000-08-15	Conjugados imunogênicos compreendendo uma porina meningocóccica de grupo b e um polissacarìdeo de h. influenzae
SE8303211D0 (sv)	1983-06-07	Rena teichomycin a?712 singelfaktorer 1,2,3,4 och 5 och sett for deras framstellning
ES2103311T3 (es)	1997-09-16	Compuestos heterociclicos.
ATE268384T1 (de)	2004-06-15	Analog von haemophilus hin47 mit verminderter protease aktivität
DK1053018T3 (da)	2005-08-15	Administration af immunogene molekyler via HBsAg-partikler
DE60137146D1 (de)	2009-02-05	Fusionszellen und zytokin-zusammensetzungen zur behandlung von krankheiten
ATE515258T1 (de)	2011-07-15	Mukosales verabreichungssytem
TW200504216A (en)	2005-02-01	Immunization of fish with plant-expressed recombinant proteins
WO2003022225A3 (fr)	2004-02-12	Compositions comprenant des melanges de proteines therapeutiques et leurs procedes de preparation
ATE385809T1 (de)	2008-03-15	Saponin-zusammensetzungen und deren verwendung
EP2347764A3 (fr)	2011-10-26	Procédé pour obtenir des structures cochléaires, des compositions de vaccins, des adjuvants et leurs intermédiaires
DK0858345T3 (da)	2003-02-24	Anvendelse af muteiner af vildtypecytokiner som immunogener
MXPA05004849A (es)	2006-03-08	Novedosas composiciones de multiples peptidos antigenicos relacionados con inhibina, que mejoran el desempeno de produccion avicola.
ES2012815A6 (es)	1990-04-16	Un metodo para producir peptidos antigenicos relacionados con el antigeno p97 asociado a melanoma, y para preparar vacunas que los contienen.
WO1999022763A3 (fr)	1999-08-05	Immunomodulateurs encapsules utilises comme adjuvants de vaccins
DK0542895T3 (da)	1997-05-12	Krydsreaktiv influenza A immunisering
GB2358352A (en)	2001-07-25	Bacterial extract as oral adjuvant