DK0808367T3 - Vaskulære slimhindeaddressiner samt anvendelse deraf - Google Patents

Vaskulære slimhindeaddressiner samt anvendelse deraf

Info

Publication number: DK0808367T3
Authority: DK; Denmark
Prior art keywords: madcam; primate; recombinant; proteins; relates
Prior art date: 1995-02-10

Application number

DK96906504T

Other languages

Danish (da)

English (en)

Inventor

Michael J Briskin

Douglas J Ringler

Dominic Picarella

Walter Newman

Original Assignee

Millennium Pharm Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-02-10

Filing date

1996-02-12

Publication date

2007-11-05

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27011628&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK0808367(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1995-02-10 Priority claimed from US08/386,857 external-priority patent/US6551593B1/en

1995-09-01 Priority claimed from US08/523,004 external-priority patent/US7750137B2/en

1996-02-12 Application filed by Millennium Pharm Inc filed Critical Millennium Pharm Inc

2007-11-05 Application granted granted Critical

2007-11-05 Publication of DK0808367T3 publication Critical patent/DK0808367T3/da

Links

230000002792 vascular Effects 0.000 title 1
241000288906 Primates Species 0.000 abstract 5
102000039446 nucleic acids Human genes 0.000 abstract 4
108020004707 nucleic acids Proteins 0.000 abstract 4
150000007523 nucleic acids Chemical class 0.000 abstract 4
210000000265 leukocyte Anatomy 0.000 abstract 3
210000004027 cell Anatomy 0.000 abstract 2
210000001035 gastrointestinal tract Anatomy 0.000 abstract 2
102000004169 proteins and genes Human genes 0.000 abstract 2
208000022559 Inflammatory bowel disease Diseases 0.000 abstract 1
108091005461 Nucleic proteins Proteins 0.000 abstract 1
102000007056 Recombinant Fusion Proteins Human genes 0.000 abstract 1
108010008281 Recombinant Fusion Proteins Proteins 0.000 abstract 1
239000005557 antagonist Substances 0.000 abstract 1
238000003556 assay Methods 0.000 abstract 1
239000003795 chemical substances by application Substances 0.000 abstract 1
201000010099 disease Diseases 0.000 abstract 1
208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
210000003038 endothelium Anatomy 0.000 abstract 1
238000000338 in vitro Methods 0.000 abstract 1
239000003112 inhibitor Substances 0.000 abstract 1
238000004519 manufacturing process Methods 0.000 abstract 1
238000000034 method Methods 0.000 abstract 1
229920001184 polypeptide Polymers 0.000 abstract 1
102000004196 processed proteins & peptides Human genes 0.000 abstract 1
108090000765 processed proteins & peptides Proteins 0.000 abstract 1
108090000623 proteins and genes Proteins 0.000 abstract 1
230000007115 recruitment Effects 0.000 abstract 1
230000001225 therapeutic effect Effects 0.000 abstract 1
210000001519 tissue Anatomy 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Immunology (AREA)
Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Molecular Biology (AREA)
Medicinal Chemistry (AREA)
Organic Chemistry (AREA)
Hematology (AREA)
Biomedical Technology (AREA)
Biochemistry (AREA)
Urology & Nephrology (AREA)
Cell Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Microbiology (AREA)
Chemical Kinetics & Catalysis (AREA)
Biophysics (AREA)
Biotechnology (AREA)
Gastroenterology & Hepatology (AREA)
Zoology (AREA)
Toxicology (AREA)
Food Science & Technology (AREA)
Physics & Mathematics (AREA)
Analytical Chemistry (AREA)
General Physics & Mathematics (AREA)
Pathology (AREA)
Bioinformatics & Cheminformatics (AREA)
Genetics & Genomics (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Peptides Or Proteins (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
External Artificial Organs (AREA)

DK96906504T 1995-02-10 1996-02-12 Vaskulære slimhindeaddressiner samt anvendelse deraf DK0808367T3 (da)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US08/386,857 US6551593B1 (en)	1995-02-10	1995-02-10	Treatment of Inflammatory bowel disease by inhibiting binding and/or signalling through α 4 β 7 and its ligands and madcam
US08/523,004 US7750137B2 (en)	1995-09-01	1995-09-01	Mucosal vascular addressins
PCT/US1996/002153 WO1996024673A1 (fr)	1995-02-10	1996-02-12	Adressines vasculaires de muqueuses et leurs utilisations

Publications (1)

Publication Number	Publication Date
DK0808367T3 true DK0808367T3 (da)	2007-11-05

Family

ID=27011628

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK96906504T DK0808367T3 (da)	1995-02-10	1996-02-12	Vaskulære slimhindeaddressiner samt anvendelse deraf

Country Status (12)

Country	Link
EP (1)	EP0808367B1 (fr)
JP (1)	JP4205162B2 (fr)
AT (1)	ATE366809T1 (fr)
AU (1)	AU4986296A (fr)
CA (1)	CA2212702C (fr)
DE (1)	DE69637155T2 (fr)
DK (1)	DK0808367T3 (fr)
ES (1)	ES2290955T3 (fr)
MX (1)	MX9706049A (fr)
NZ (1)	NZ303523A (fr)
PT (1)	PT808367E (fr)
WO (1)	WO1996024673A1 (fr)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JP2001503271A (ja) *	1996-11-01	2001-03-13	ヒューマンジノームサイエンシーズ，インコーポレイテッド	ヒト粘膜アドレシン細胞接着分子―１（ＭＡｄＣＡＭ―１）およびそのスプライス変異体
AU7348798A (en) *	1997-05-09	1998-12-08	John P. Robarts Research Institute, The	Method for dislodging infiltrated leukocytes from a tissue
AU2007201698B2 (en) *	1998-05-13	2011-10-13	Genentech, Inc.	Diagnosis and treatment of hepatic disorders
US7090845B2 (en)	1998-05-13	2006-08-15	Genentech, Inc.	Diagnosis and treatment of hepatic disorders
ATE424417T1 (de) *	1998-05-13	2009-03-15	Genentech Inc	Diagnose und behandlung von hepatischen krankheiten
AUPR524101A0 (en)	2001-05-25	2001-06-21	Council Of The Queensland Institute Of Medical Research, The	Antigen targeting
WO2003047526A2 (fr) *	2001-11-30	2003-06-12	Incyte Genomics, Inc.	Proteines d'adhesion cellulaire et de matrice extracellulaire
WO2004081049A1 (fr) *	2003-03-10	2004-09-23	Auckland Uniservices Limited	Anticorps monoclonaux reconnaissant la molecule d'adherence cellulaire d'adressine des muqueuses, forme soluble de madcam-1, et utilisations
RU2349598C2 (ru) *	2003-05-01	2009-03-20	Дзе Скриппс Рисерч Инститьют	Селективные антагонисты r-кадгерина и способы
DOP2005000002A (es)	2004-01-09	2005-08-15	Pfizer	"anticuerpos contra madcam"
RS57636B1 (sr) *	2004-09-03	2018-11-30	Genentech Inc	Humanizovani anti-beta7 antagonisti i njihova upotreba
DE602006017373D1 (de)	2005-07-08	2010-11-18	Pfizer Ltd	Madcam-antikörper
WO2007007152A2 (fr) *	2005-07-11	2007-01-18	Pfizer Limited	Anticorps anti-madcam utilises pour le traitement de cancers metastatiques et du chlorome
EP2279004B1 (fr) *	2008-05-16	2015-01-14	F. Hoffmann-La Roche AG	Utilisation de biomarqueurs pour évaluer le traitement de troubles inflammatoires gastro-intestinaux avec des antagonistes de l'intégrine bêta7
MX384203B (es)	2011-05-02	2025-03-14	Takeda Pharmaceuticals Co	FORMULACION PARA ANTICUERPO ANTI -A4ß7.
UA116189C2 (uk)	2011-05-02	2018-02-26	Мілленніум Фармасьютікалз, Інк.	КОМПОЗИЦІЯ АНТИ-α4β7 АНТИТІЛА
JP2017537105A (ja)	2014-11-26	2017-12-14	ミレニアムファーマシューティカルズ，インコーポレイテッドＭｉｌｌｅｎｎｉｕｍＰｈａｒｍａｃｅｕｔｉｃａｌｓ，Ｉｎｃ．	瘻孔を伴うクローン病の治療用ベドリズマブ
EP3237004B1 (fr)	2014-12-24	2024-05-08	Takeda Pharmaceutical Company Limited	Prévision du résultat de traitement avec un anticorps dirigé contre l'intégrine anti-alpha4 beta7
MA41636A (fr)	2015-03-06	2018-01-09	Millennium Pharm Inc	Méthode de traitement de la cholangite sclérosante primitive
EP3430053A1 (fr)	2016-03-14	2019-01-23	Millennium Pharmaceuticals, Inc.	Méthodes de traitement ou de prévention d'une maladie du greffon contre l'hôte
EP3430052A2 (fr)	2016-03-14	2019-01-23	Millennium Pharmaceuticals, Inc.	Méthode de traitement de la réaction du greffon contre l'hôte (gvd)
US11760803B2 (en)	2016-03-24	2023-09-19	Takeda Pharmaceutical Company Limited	Methods of treating gastrointestinal immune-related adverse events in immune oncology treatments
TW201735949A (zh)	2016-03-24	2017-10-16	千禧製藥公司	治療抗ctla4及抗pd-1組合治療中的胃腸道免疫相關不良事件之方法
US10918716B2 (en)	2016-05-04	2021-02-16	Millennium Pharmaceuticals, Inc.	Triple combination therapy for treating Crohn's disease
US11389533B2 (en)	2016-06-12	2022-07-19	Takeda Pharmaceutical Company Limited	Method of treating inflammatory bowel disease
WO2018104893A1 (fr)	2016-12-06	2018-06-14	Glaxosmithkline Intellectual Property Development Limited	Anticorps anti-alpha4-beta7 présentant une liaison à fcrn et/ou une demi-vie augmentées
JP2020517671A (ja)	2017-04-28	2020-06-18	ミレニアムファーマシューティカルズ，インコーポレイテッドＭｉｌｌｅｎｎｉｕｍＰｈａｒｍａｃｅｕｔｉｃａｌｓ，Ｉｎｃ．	小児の障害を処置する方法
TW201920266A (zh)	2017-07-14	2019-06-01	美商輝瑞大藥廠	Madcam 抗體
US11739146B2 (en) *	2019-05-20	2023-08-29	Pandion Operations, Inc.	MAdCAM targeted immunotolerance
WO2024252368A2 (fr)	2023-06-09	2024-12-12	Takeda Pharmaceutical Company Limited	Procédés et compositions pour le traitement de la rectocolite hémorragique

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AU5675794A (en) *	1992-12-15	1994-07-04	Board Of Trustees Of The Leland Stanford Junior University	Mucosal vascular addressin, dna and expression

1996
- 1996-02-12 PT PT96906504T patent/PT808367E/pt unknown
- 1996-02-12 DK DK96906504T patent/DK0808367T3/da active
- 1996-02-12 EP EP96906504A patent/EP0808367B1/fr not_active Revoked
- 1996-02-12 MX MX9706049A patent/MX9706049A/es active IP Right Grant
- 1996-02-12 CA CA2212702A patent/CA2212702C/fr not_active Expired - Lifetime
- 1996-02-12 DE DE69637155T patent/DE69637155T2/de not_active Expired - Lifetime
- 1996-02-12 NZ NZ303523A patent/NZ303523A/en not_active IP Right Cessation
- 1996-02-12 ES ES96906504T patent/ES2290955T3/es not_active Expired - Lifetime
- 1996-02-12 AU AU49862/96A patent/AU4986296A/en not_active Abandoned
- 1996-02-12 JP JP52449196A patent/JP4205162B2/ja not_active Expired - Fee Related
- 1996-02-12 WO PCT/US1996/002153 patent/WO1996024673A1/fr active IP Right Grant
- 1996-02-12 AT AT96906504T patent/ATE366809T1/de active

Also Published As

Publication number	Publication date
DE69637155D1 (de)	2007-08-23
JP4205162B2 (ja)	2009-01-07
NZ303523A (en)	2002-02-01
ATE366809T1 (de)	2007-08-15
EP0808367B1 (fr)	2007-07-11
JPH10513365A (ja)	1998-12-22
CA2212702C (fr)	2010-04-20
PT808367E (pt)	2007-10-22
EP0808367A1 (fr)	1997-11-26
CA2212702A1 (fr)	1996-08-15
WO1996024673A1 (fr)	1996-08-15
AU4986296A (en)	1996-08-27
MX9706049A (es)	1998-02-28
DE69637155T2 (de)	2008-02-07
ES2290955T3 (es)	2008-02-16

Publication	Publication Date	Title
DK0808367T3 (da)	2007-11-05	Vaskulære slimhindeaddressiner samt anvendelse deraf
Geiser et al.	1993	The interleukin-8-related chemotactic cytokines GRO alpha, GRO beta, and GRO gamma activate human neutrophil and basophil leukocytes
Pearse	1988	Receptors compete for adaptors found in plasma membrane coated pits.
RU2734169C2 (ru)	2020-10-13	Способ получения повышающей регуляции экспрессии PD-L1, полипептиды, конъюгат, слитый полипептид, композиция и комбинация для обеспечения повышающей регуляции экспрессии PD-L1
Timpl et al.	1982	[47] Laminin
DE60219611T2 (de)	2007-12-27	Modifizierte annexin-proteine und verhinderung und behandlung von thrombose
US20060173162A1 (en)	2006-08-03	Bactericidak anti-apoptotic, pro-inflammatory and anti-inflammatory peptides of heparin-binding protein (hbp)
KR100451446B1 (ko)	2004-10-06	아글리코 생성물 및 그의 사용 방법
JP2742925B2 (ja)	1998-04-22	血栓形成抑制用治療薬組成物
JP2512453B2 (ja)	1996-07-03	天然のコロニ−促進因子―１の精製
JP2004043502A (ja)	2004-02-12	新規蛋白質及びこれを使用した薬剤の製法
JPH03204896A (ja)	1991-09-06	インターフェロンレセプター細胞外断片
EP1399476B1 (fr)	2006-08-16	Utilisation de fragments solubles de cytokeratine-1 en diagnostic
JP4794102B2 (ja)	2011-10-19	フィブリンのシトルリン誘導体及び慢性関節リウマチの診断又は治療のためのその使用
WO1994025476A1 (fr)	1994-11-10	Proteines de recombinaison de type augmentant la permeabilite bactericide (bpi) et de type fixant le liposaccharide (lbd), molecules codant pour ces proteines, leurs procedes de production et leurs utilisations
HU226468B1 (en)	2008-12-29	Amino-terminally truncated mcp-2-as chemokine antagonists
EP1683866B1 (fr)	2017-03-01	Formes délétées du facteur de libération de l'histamine (HRF) dépendant de l'IgE qui sont capable de promouvoir la libération de l'histamine, des peptides capables de fixer l'HRF et leurs utilisations
McNaughton et al.	2018	Novel anti-inflammatory peptides based on chemokine–glycosaminoglycan interactions reduce leukocyte migration and disease severity in a model of rheumatoid arthritis
EA009414B1 (ru)	2007-12-28	Терапевтические применения вариантов хемокинов
Bond et al.	1993	Native and recombinant Fel dI as probes into the relationship of allergen structure to human IgE immunoreactivity
Campistol et al.	1996	Polymerization of normal and intact β2-microglobulin as the amyloidogenic protein in dialysis-amyloidosis
CN111848780A (zh)	2020-10-30	一种IL-36的可溶性受体sIL-36R及其应用
EP0698666B1 (fr)	2006-04-26	Epimorphine modifiée
Plager et al.	2001	A novel human homolog of eosinophil major basic protein
JP3103531B2 (ja)	2000-10-30	ヒト尿由来細胞接着糖蛋白質及びその製造方法