DK0666841T3 - Succinoylamino-hydroxyethylaminosulfaminsyrederivater til anvendelse som inhibitorer af retrovirale proteaser - Google Patents
Succinoylamino-hydroxyethylaminosulfaminsyrederivater til anvendelse som inhibitorer af retrovirale proteaserInfo
- Publication number
- DK0666841T3 DK0666841T3 DK94901230.6T DK94901230T DK0666841T3 DK 0666841 T3 DK0666841 T3 DK 0666841T3 DK 94901230 T DK94901230 T DK 94901230T DK 0666841 T3 DK0666841 T3 DK 0666841T3
- Authority
- DK
- Denmark
- Prior art keywords
- inhibitors
- succinoylamino
- hydroxyethylaminosulfamic
- acid derivatives
- retroviral proteases
- Prior art date
Links
- 239000003112 inhibitor Substances 0.000 title abstract 2
- 230000001177 retroviral effect Effects 0.000 title abstract 2
- 102000035195 Peptidases Human genes 0.000 title 1
- 108091005804 Peptidases Proteins 0.000 title 1
- 239000004365 Protease Substances 0.000 title 1
- 239000002253 acid Substances 0.000 title 1
- 108010010369 HIV Protease Proteins 0.000 abstract 1
- 229940042399 direct acting antivirals protease inhibitors Drugs 0.000 abstract 1
- -1 hydroxyethylamino sulfamic acid derivative compounds Chemical class 0.000 abstract 1
- 239000000137 peptide hydrolase inhibitor Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/22—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with hetero atoms directly attached to ring nitrogen atoms
- C07D295/26—Sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C307/00—Amides of sulfuric acids, i.e. compounds having singly-bound oxygen atoms of sulfate groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C307/04—Diamides of sulfuric acids
- C07C307/06—Diamides of sulfuric acids having nitrogen atoms of the sulfamide groups bound to acyclic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/02—Systems containing only non-condensed rings with a three-membered ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/04—Systems containing only non-condensed rings with a four-membered ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
- C07C2601/08—Systems containing only non-condensed rings with a five-membered ring the ring being saturated
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US96968392A | 1992-10-30 | 1992-10-30 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0666841T3 true DK0666841T3 (da) | 1997-02-10 |
Family
ID=25515855
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK94901230.6T DK0666841T3 (da) | 1992-10-30 | 1993-10-29 | Succinoylamino-hydroxyethylaminosulfaminsyrederivater til anvendelse som inhibitorer af retrovirale proteaser |
Country Status (9)
| Country | Link |
|---|---|
| EP (1) | EP0666841B1 (fr) |
| AT (1) | ATE148105T1 (fr) |
| AU (1) | AU5589294A (fr) |
| CA (1) | CA2141570A1 (fr) |
| DE (1) | DE69307726T2 (fr) |
| DK (1) | DK0666841T3 (fr) |
| ES (1) | ES2097023T3 (fr) |
| GR (1) | GR3023044T3 (fr) |
| WO (1) | WO1994010133A1 (fr) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6407134B1 (en) | 1995-03-10 | 2002-06-18 | G. D. Searle & Co. | Heterocyclecarbonyl amino acid hydroxyethylamino sulfonamide retroviral protease inhibitors |
| PL184771B1 (pl) * | 1995-03-10 | 2002-12-31 | Searle & Co | Związek stanowiący hydroksyetyloaminosulfonamid pirolidynokarbonyloaminokwasu, kompozycja zawierająca ten związek, jego zastosowanie do wytwarzania kompozycji do leczenia infekcji retrowirusowej i sposób zapobiegania replikacji retrowirusa in vitro |
| US5776971A (en) * | 1995-03-10 | 1998-07-07 | G.D. Searle & Co. | Heterocyclecarbonyl amino acid hydroxyethylamino sulfonamide retroviral protease inhibitors |
| DE19703713A1 (de) * | 1997-01-23 | 1998-07-30 | Hans Prof Dr Schick | Verfahren für die Herstellung von Oxetan-2-onen und Zwischenprodukte |
| WO2016040084A1 (fr) * | 2014-09-09 | 2016-03-17 | Bristol-Myers Squibb Company | Inhibiteurs de la réplication du virus de l'immunodéficience humaine |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH676988A5 (fr) * | 1987-01-21 | 1991-03-28 | Sandoz Ag | |
| DE3830825A1 (de) * | 1987-09-15 | 1989-03-23 | Sandoz Ag | Hydrophile reninhemmer, ihre herstellung und verwendung |
| ES2059289T3 (es) * | 1990-11-19 | 1997-10-16 | Monsanto Co | Inhibidores de la proteasa retroviral. |
| ATE296625T1 (de) * | 1990-11-19 | 2005-06-15 | Monsanto Co | Retrovirusprotease inhibitoren |
-
1993
- 1993-10-29 DE DE69307726T patent/DE69307726T2/de not_active Expired - Fee Related
- 1993-10-29 ES ES94901230T patent/ES2097023T3/es not_active Expired - Lifetime
- 1993-10-29 AU AU55892/94A patent/AU5589294A/en not_active Abandoned
- 1993-10-29 AT AT94901230T patent/ATE148105T1/de not_active IP Right Cessation
- 1993-10-29 DK DK94901230.6T patent/DK0666841T3/da active
- 1993-10-29 WO PCT/US1993/010460 patent/WO1994010133A1/fr active IP Right Grant
- 1993-10-29 CA CA002141570A patent/CA2141570A1/fr not_active Abandoned
- 1993-10-29 EP EP94901230A patent/EP0666841B1/fr not_active Expired - Lifetime
-
1997
- 1997-04-04 GR GR970400711T patent/GR3023044T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU5589294A (en) | 1994-05-24 |
| ES2097023T3 (es) | 1997-03-16 |
| GR3023044T3 (en) | 1997-07-30 |
| EP0666841A1 (fr) | 1995-08-16 |
| ATE148105T1 (de) | 1997-02-15 |
| EP0666841B1 (fr) | 1997-01-22 |
| DE69307726T2 (de) | 1997-06-05 |
| CA2141570A1 (fr) | 1994-05-11 |
| DE69307726D1 (de) | 1997-03-06 |
| WO1994010133A1 (fr) | 1994-05-11 |
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