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DK0598840T3 - Humane calciumkanal sammensætninger og fremgangsmåder - Google Patents

Humane calciumkanal sammensætninger og fremgangsmåder

Info

Publication number
DK0598840T3
DK0598840T3 DK92918611T DK92918611T DK0598840T3 DK 0598840 T3 DK0598840 T3 DK 0598840T3 DK 92918611 T DK92918611 T DK 92918611T DK 92918611 T DK92918611 T DK 92918611T DK 0598840 T3 DK0598840 T3 DK 0598840T3
Authority
DK
Denmark
Prior art keywords
human calcium
methods
calcium channel
channel compositions
compositions
Prior art date
Application number
DK92918611T
Other languages
Danish (da)
English (en)
Inventor
Michael Miller Harpold
Steven Bradley Ellis
Mark Edward Williams
Daniel Howard Feldman
Ann Francis Mccue
Robert Brenner
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US07/745,206 external-priority patent/US5429921A/en
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Application granted granted Critical
Publication of DK0598840T3 publication Critical patent/DK0598840T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cosmetics (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Curing Cements, Concrete, And Artificial Stone (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DK92918611T 1991-08-15 1992-08-14 Humane calciumkanal sammensætninger og fremgangsmåder DK0598840T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US07/745,206 US5429921A (en) 1988-04-04 1991-08-15 Assays for agonists and antagonists of recombinant human calcium channels
US86835492A 1992-04-10 1992-04-10
PCT/US1992/006903 WO1993004083A1 (fr) 1991-08-15 1992-08-14 Compositions de canaux calciques humains et procedes

Publications (1)

Publication Number Publication Date
DK0598840T3 true DK0598840T3 (da) 2000-10-02

Family

ID=27114421

Family Applications (1)

Application Number Title Priority Date Filing Date
DK92918611T DK0598840T3 (da) 1991-08-15 1992-08-14 Humane calciumkanal sammensætninger og fremgangsmåder

Country Status (10)

Country Link
EP (3) EP0598840B1 (fr)
JP (1) JPH06509717A (fr)
AT (2) ATE191920T1 (fr)
AU (1) AU677571B2 (fr)
CA (1) CA2113203C (fr)
DE (2) DE69233469T2 (fr)
DK (1) DK0598840T3 (fr)
ES (2) ES2147184T3 (fr)
GR (1) GR3033961T3 (fr)
WO (1) WO1993004083A1 (fr)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5876958A (en) * 1988-04-04 1999-03-02 Sibia Neurosciences, Inc. Assays of cells expressing human calcium channels containing α1 β subunits
US6387696B1 (en) * 1988-04-04 2002-05-14 Merck & Co., Inc. Human calcium channel compositions and methods
US5874236A (en) * 1988-04-04 1999-02-23 Sibia Neurosciences. Inc. DNA encoding human calcium channel α-1A, β1, β-2, and β-4 subunits, and assays using cells that express the subunits
US5386025A (en) * 1990-02-20 1995-01-31 The Salk Institute Biotechnology/Industrial Associates Calcium channel compositions and methods
US5912122A (en) * 1993-06-04 1999-06-15 Sibia Neurosciences, Inc. Nucleic acids encoding and method for detecting nucleic acid encoding human metabotropic glutamate receptor subtype mGluR6
US5623051A (en) * 1994-11-10 1997-04-22 University Of Washington Methods and compositions for screening for presynaptic calcium channel blockers
US5712158A (en) * 1995-06-06 1998-01-27 Warner-Lambert Company Cell line for the rapid expression of functional calcium channels
US6040436A (en) * 1996-09-16 2000-03-21 American Home Products Corporation Nucleic acid encoding human neuronal calcium channel subunits
CA2312195A1 (fr) * 1997-12-03 1999-06-10 Merck & Co., Inc. Compositions a canaux calcium actives a basse tension et procedes correspondants
CA2312477A1 (fr) * 1997-12-05 1999-06-17 Loyola University Of Chicago Canaux calciques potentiel-dependants de type t et leurs methodes d'utilisation
WO1999046383A1 (fr) 1998-03-13 1999-09-16 Brown University Research Foundation Isoforme de canal calcique humain de type n et utilisations
CA2299611A1 (fr) 1998-06-02 1999-12-09 Torben Bech-Hansen Gene de sous-unite 1f(alpha) du canal calcique retinal
CA2365440A1 (fr) * 1999-05-05 2000-11-09 Lexicon Genetics Incorporated Nouvelles proteines de canal ionique de l'homme
CA2384911C (fr) 1999-09-16 2008-07-22 Warner-Lambert Company Methode de criblage de ligands de liaison a la sous-unite .alpha.2.delta.-1
US6962973B1 (en) 1999-09-16 2005-11-08 Warner-Lambert Company Porcine α2δ-1 calcium channel subunit cDNA and soluble secreted α2δ-1 subunit polypeptides
US6783952B1 (en) 1999-09-16 2004-08-31 Warner-Lambert Company Secreted soluble α2δ-2, α2δ-3 or α2δ-4 calcium channel subunit polypeptides and screening assays using same
ATE405156T1 (de) * 1999-10-26 2008-09-15 Eisai R&D Man Co Ltd N-KALZIUM-KANAL-ßKNOCKOUT-TIERß
US7067714B1 (en) 1999-10-26 2006-06-27 Eisai Research Institute N-calcium channel knockout animal
US7294691B1 (en) 2000-09-18 2007-11-13 Warner Lambert Company Soluble secreted α2δ-2calcium channel subunit polypeptide
WO2003079025A2 (fr) 2002-03-19 2003-09-25 Novartis Ag Procedes d'identification de composes utiles pour la suppression de la douleur neuropathique chronique et compositions associees

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4950739A (en) * 1988-02-10 1990-08-21 New York University Membrane calcium channels and factors and methods for blocking, isolating and purifying calcium channels
US5386025A (en) * 1990-02-20 1995-01-31 The Salk Institute Biotechnology/Industrial Associates Calcium channel compositions and methods
EP0424397B1 (fr) * 1988-04-04 1996-06-19 The Salk Institute Biotechnology Industrial Associates, Inc. Compositions a canal de calcium et procedes associes
DE4110785A1 (de) * 1991-04-04 1992-10-08 Bayer Ag Gewebe-spezifische humane neuronale calcium-kanal-subtypen und deren verwendung

Also Published As

Publication number Publication date
EP0992585B1 (fr) 2005-01-12
GR3033961T3 (en) 2000-11-30
DE69233469T2 (de) 2005-12-22
CA2113203A1 (fr) 1993-03-04
EP0598840A1 (fr) 1994-06-01
AU677571B2 (en) 1997-05-01
JPH06509717A (ja) 1994-11-02
DE69230938T2 (de) 2000-10-12
EP0598840B1 (fr) 2000-04-19
ES2235417T3 (es) 2005-07-01
ATE286976T1 (de) 2005-01-15
DE69233469D1 (de) 2005-02-17
DE69230938D1 (de) 2000-05-25
ATE191920T1 (de) 2000-05-15
AU2495792A (en) 1993-03-16
EP0992585A3 (fr) 2000-11-15
EP1469074A1 (fr) 2004-10-20
EP0992585A2 (fr) 2000-04-12
ES2147184T3 (es) 2000-09-01
EP1469074B1 (fr) 2008-11-26
CA2113203C (fr) 2001-01-02
WO1993004083A1 (fr) 1993-03-04

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