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DK0596036T3 - Indretning til afgivelse gennem huden - Google Patents

Indretning til afgivelse gennem huden

Info

Publication number
DK0596036T3
DK0596036T3 DK92917863.0T DK92917863T DK0596036T3 DK 0596036 T3 DK0596036 T3 DK 0596036T3 DK 92917863 T DK92917863 T DK 92917863T DK 0596036 T3 DK0596036 T3 DK 0596036T3
Authority
DK
Denmark
Prior art keywords
drug
passive
reservoir
active
ionizable
Prior art date
Application number
DK92917863.0T
Other languages
Danish (da)
English (en)
Inventor
Ronald P Haak
Richard J Gyory
Felix Theeuwes
Original Assignee
Alza Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alza Corp filed Critical Alza Corp
Application granted granted Critical
Publication of DK0596036T3 publication Critical patent/DK0596036T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/0404—Electrodes for external use
    • A61N1/0408—Use-related aspects
    • A61N1/0428—Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
    • A61N1/0448—Drug reservoir
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0009—Galenical forms characterised by the drug release technique; Application systems commanded by energy involving or responsive to electricity, magnetism or acoustic waves; Galenical aspects of sonophoresis, iontophoresis, electroporation or electroosmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/0404—Electrodes for external use
    • A61N1/0408—Use-related aspects
    • A61N1/0428—Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
    • A61N1/0432—Anode and cathode
    • A61N1/0436—Material of the electrode
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/0404—Electrodes for external use
    • A61N1/0408—Use-related aspects
    • A61N1/0428—Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
    • A61N1/0432—Anode and cathode
    • A61N1/044—Shape of the electrode
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/0404—Electrodes for external use
    • A61N1/0408—Use-related aspects
    • A61N1/0428—Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
    • A61N1/0444—Membrane

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Radiology & Medical Imaging (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Electrotherapy Devices (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Bidet-Like Cleaning Device And Other Flush Toilet Accessories (AREA)
  • External Artificial Organs (AREA)
  • Saccharide Compounds (AREA)
  • Surgical Instruments (AREA)
  • Refuse Collection And Transfer (AREA)
  • Apparatuses For Bulk Treatment Of Fruits And Vegetables And Apparatuses For Preparing Feeds (AREA)
DK92917863.0T 1991-07-24 1992-07-22 Indretning til afgivelse gennem huden DK0596036T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/735,126 US5203768A (en) 1991-07-24 1991-07-24 Transdermal delivery device

Publications (1)

Publication Number Publication Date
DK0596036T3 true DK0596036T3 (da) 1995-12-04

Family

ID=24954476

Family Applications (1)

Application Number Title Priority Date Filing Date
DK92917863.0T DK0596036T3 (da) 1991-07-24 1992-07-22 Indretning til afgivelse gennem huden

Country Status (14)

Country Link
US (1) US5203768A (fr)
EP (1) EP0596036B1 (fr)
JP (1) JPH06509254A (fr)
AT (1) ATE127340T1 (fr)
AU (1) AU2426792A (fr)
DE (1) DE69204676T2 (fr)
DK (1) DK0596036T3 (fr)
ES (1) ES2076779T3 (fr)
GR (1) GR3017333T3 (fr)
IE (1) IE71032B1 (fr)
MX (1) MX9204304A (fr)
PT (1) PT100720A (fr)
WO (1) WO1993001807A1 (fr)
ZA (1) ZA925513B (fr)

Families Citing this family (141)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6956032B1 (en) * 1986-04-18 2005-10-18 Carnegie Mellon University Cyanine dyes as labeling reagents for detection of biological and other materials by luminescence methods
US5656286A (en) * 1988-03-04 1997-08-12 Noven Pharmaceuticals, Inc. Solubility parameter based drug delivery system and method for altering drug saturation concentration
US5374241A (en) * 1989-07-21 1994-12-20 Iomed, Inc. Electrodes for iontophoresis
US6331318B1 (en) * 1994-09-30 2001-12-18 Emisphere Technologies Inc. Carbon-substituted diketopiperazine delivery systems
US5464387A (en) * 1991-07-24 1995-11-07 Alza Corporation Transdermal delivery device
CA2087087C (fr) * 1992-01-22 2000-07-18 Burton H. Sage, Jr. Molecules pour administration par ionophorese
FR2687321B1 (fr) * 1992-02-14 1999-04-16 Elf Aquitaine Dispositif d'ionophorese pour l'administration transcutanee d'une quantite totale donnee d'un principe actif a un sujet.
AU5551394A (en) * 1992-11-09 1994-06-08 Pharmetrix Corporation Combined analgesic delivery methods for pain management
US5387189A (en) * 1993-12-02 1995-02-07 Alza Corporation Electrotransport delivery device and method of making same
US5843015A (en) * 1993-12-28 1998-12-01 Becton Dickinson And Company Molecules for iontophoretic delivery
AU2682795A (en) * 1994-06-17 1996-01-15 Hisamitsu Pharmaceutical Co., Inc. Electrode for iontophoresis and device using the same
US7027859B1 (en) * 1994-09-26 2006-04-11 Alza Corporation Electrotransport delivery device having improved safety and reduced abuse potential
US5843014A (en) * 1995-03-24 1998-12-01 Alza Corporation Display for an electrotransport delivery device
US5879322A (en) * 1995-03-24 1999-03-09 Alza Corporation Self-contained transdermal drug delivery device
US5990179A (en) * 1995-04-28 1999-11-23 Alza Corporation Composition and method of enhancing electrotransport agent delivery
US5985316A (en) * 1995-04-28 1999-11-16 Alza Corporation Composition and method of enhancing electrotransport agent delivery
US6881208B1 (en) * 1995-06-05 2005-04-19 Joseph B. Phipps Method and device for transdermal electrotransport delivery of fentanyl and sufentanil
US6425892B2 (en) * 1995-06-05 2002-07-30 Alza Corporation Device for transdermal electrotransport delivery of fentanyl and sufentanil
WO1996039222A1 (fr) * 1995-06-05 1996-12-12 Alza Corporation Dispositif d'administration transdermique de fentanyl et de sufentanil par electrotransport
ZA964320B (en) * 1995-06-05 1997-01-13 Alza Corp Device for transdermal electrotransport delivery of fentanyl and sufentanil
US6216033B1 (en) * 1996-05-22 2001-04-10 Alza Corporation Device for transdermal electrotransport delivery of fentanyl and sufentanil
US7572252B1 (en) * 1995-06-07 2009-08-11 Alza Corporation Electrotransport agent delivery method and apparatus
US5983130A (en) * 1995-06-07 1999-11-09 Alza Corporation Electrotransport agent delivery method and apparatus
DE69629628T2 (de) 1995-06-14 2004-06-17 Hisamitsu Pharmaceutical Co., Inc., Tosu Schnittstelle für Iontophorese
US5891461A (en) * 1995-09-14 1999-04-06 Cygnus, Inc. Transdermal administration of olanzapine
US5807570A (en) * 1995-09-29 1998-09-15 Cygnus, Inc. Transdermal administration of ropinirole and analogs thereof
WO1997014473A1 (fr) * 1995-10-18 1997-04-24 Novartis Ag Dispositif d'apport transdermique de medicament, commande par une thermopile
US6385487B1 (en) 1996-05-08 2002-05-07 Biophoretic Therapeutic Systems, Llc Methods for electrokinetic delivery of medicaments
US5676648A (en) 1996-05-08 1997-10-14 The Aps Organization, Llp Iontophoretic drug delivery apparatus and method for use
US6718201B1 (en) * 1996-06-07 2004-04-06 Alza Corporation Electrotransport agent delivery method and apparatus
AU3404097A (en) * 1996-06-19 1998-01-07 Becton Dickinson & Company Iontophoretic delivery of cell adhesion inhibitors
US5848966A (en) * 1997-03-04 1998-12-15 Graphic Controls Corporation Medical device easily removed from skin and a method of removal therefrom
US6119036A (en) * 1997-03-26 2000-09-12 The Board Of Regents Of The University Of Oklahoma Iontophoretic transdermal delivery device
US6029083A (en) * 1997-04-04 2000-02-22 Becton, Dickinson And Company Circuit and method for automatically turning off an iontophoresis system
US5882677A (en) * 1997-09-30 1999-03-16 Becton Dickinson And Company Iontophoretic patch with hydrogel reservoir
EP1030560B1 (fr) 1997-10-09 2007-09-26 Emory University Procede et dispositif d'administration transdermique du lithium
USRE37796E1 (en) 1997-12-16 2002-07-23 Biophoretic Therapeutic Systems, Llc Methods for iontophoretic delivery of antiviral agents
KR100289471B1 (ko) * 1998-01-19 2001-09-17 김충섭 휀타닐계마취제의이식형서방성제제
ATE343411T1 (de) * 1998-08-31 2006-11-15 Travanti Pharma Inc Gesteuerte medikamentdosierungsvorrichtung
US6148231A (en) * 1998-09-15 2000-11-14 Biophoretic Therapeutic Systems, Llc Iontophoretic drug delivery electrodes and method
US6858018B1 (en) * 1998-09-28 2005-02-22 Vyteris, Inc. Iontophoretic devices
WO2000043058A1 (fr) * 1999-01-22 2000-07-27 Powderject Research Limited Methode favorisant l'administration transdermique sans aiguille de medicaments en poudre
US6477410B1 (en) * 2000-05-31 2002-11-05 Biophoretic Therapeutic Systems, Llc Electrokinetic delivery of medicaments
US6553253B1 (en) 1999-03-12 2003-04-22 Biophoretic Therapeutic Systems, Llc Method and system for electrokinetic delivery of a substance
US7127285B2 (en) * 1999-03-12 2006-10-24 Transport Pharmaceuticals Inc. Systems and methods for electrokinetic delivery of a substance
US6792306B2 (en) * 2000-03-10 2004-09-14 Biophoretic Therapeutic Systems, Llc Finger-mounted electrokinetic delivery system for self-administration of medicaments and methods therefor
US9006175B2 (en) 1999-06-29 2015-04-14 Mannkind Corporation Potentiation of glucose elimination
US6421561B1 (en) 1999-12-30 2002-07-16 Birch Point Medical, Inc. Rate adjustable drug delivery system
US6522918B1 (en) 2000-02-09 2003-02-18 William E. Crisp Electrolytic device
US6496727B1 (en) * 2000-05-31 2002-12-17 Becton, Dickinson And Company Medicament-loaded transdermal reservoir and method for its formation
US6629968B1 (en) * 2000-06-30 2003-10-07 Vyteris, Inc. Shelf storage stable iontophoresis reservoir-electrode and iontophoretic system incorporating the reservoir-electrode
US6653014B2 (en) 2001-05-30 2003-11-25 Birch Point Medical, Inc. Power sources for iontophoretic drug delivery systems
DE10141650C1 (de) 2001-08-24 2002-11-28 Lohmann Therapie Syst Lts Transdermales Therapeutisches System mit Fentanyl bzw. verwandten Substanzen
DE10205373B4 (de) * 2002-02-09 2007-07-19 Aloys Wobben Brandschutz
JP4681231B2 (ja) 2002-03-20 2011-05-11 マンカインド コーポレイション 吸入装置
US7458982B2 (en) * 2002-10-04 2008-12-02 Photokinetix, Inc. Photokinetic delivery of biologically active substances using pulsed incoherent light
IL152575A (en) * 2002-10-31 2008-12-29 Transpharma Medical Ltd A skin-to-skin transmission system of water-insoluble drugs
US7220778B2 (en) * 2003-04-15 2007-05-22 The General Hospital Corporation Methods and devices for epithelial protection during photodynamic therapy
US20050112151A1 (en) * 2003-11-20 2005-05-26 Horng Liou L. Skin adherent hydrogels
US8024033B2 (en) * 2004-02-27 2011-09-20 Encore Medical Asset Corporation Iontophoretic electrode
US7709639B2 (en) 2004-08-20 2010-05-04 Mannkind Corporation Catalysis of diketopiperazine synthesis
ES2540886T3 (es) 2004-08-23 2015-07-14 Mannkind Corporation Sales de dicetopiperazina para la administración de fármacos
US20060095001A1 (en) * 2004-10-29 2006-05-04 Transcutaneous Technologies Inc. Electrode and iontophoresis device
US20060135906A1 (en) * 2004-11-16 2006-06-22 Akihiko Matsumura Iontophoretic device and method for administering immune response-enhancing agents and compositions
JP2006296511A (ja) * 2005-04-15 2006-11-02 Transcutaneous Technologies Inc 外用剤、外用剤の塗布方法、イオントフォレーシス装置及び経皮パッチ
WO2006133101A2 (fr) * 2005-06-03 2006-12-14 Trans-Dermal Patents Company, Llc Systeme d'administration d'agent
US20090143761A1 (en) * 2005-06-03 2009-06-04 Transdermal Patents Company, Llc Agent delivery system and uses of same
JP2006346368A (ja) * 2005-06-20 2006-12-28 Transcutaneous Technologies Inc イオントフォレーシス装置及びその製造方法
JP2007000342A (ja) * 2005-06-23 2007-01-11 Transcutaneous Technologies Inc 複数薬剤の投与量および投与時期を制御するイオントフォレーシス装置
EP1905433A1 (fr) * 2005-07-15 2008-04-02 Transcu Ltd. Compresse absorbante percutanée avec indicateur de position d'application et dispositif d'iontophorèse
US8295922B2 (en) 2005-08-08 2012-10-23 Tti Ellebeau, Inc. Iontophoresis device
US8386030B2 (en) * 2005-08-08 2013-02-26 Tti Ellebeau, Inc. Iontophoresis device
US20070088332A1 (en) * 2005-08-22 2007-04-19 Transcutaneous Technologies Inc. Iontophoresis device
WO2007023907A1 (fr) * 2005-08-24 2007-03-01 Transcu Ltd. Structure d’électrode du type à réfrigération pour ionophorèse
WO2007026672A1 (fr) * 2005-08-29 2007-03-08 Transcu Ltd. Composition d’électrolyte universelle pour l'ionophorèse
JPWO2007029611A1 (ja) * 2005-09-06 2009-03-19 Ｔｔｉ・エルビュー株式会社 イオントフォレーシス装置
US20070112294A1 (en) * 2005-09-14 2007-05-17 Transcutaneous Technologies Inc. Iontophoresis device
AU2006290227B2 (en) 2005-09-14 2012-08-02 Mannkind Corporation Method of drug formulation based on increasing the affinity of crystalline microparticle surfaces for active agents
WO2007032446A1 (fr) * 2005-09-15 2007-03-22 Tti Ellebeau, Inc. Appareil d'iontophorèse de type à tige
WO2007032423A1 (fr) * 2005-09-16 2007-03-22 Tti Ellebeau, Inc. Appareil d'iontophorese du type a catheter
US20090299264A1 (en) * 2005-09-28 2009-12-03 Tti Ellebeau, Inc. Electrode Assembly for Dry Type Iontophoresis
RU2008117153A (ru) * 2005-09-30 2009-11-10 ТиТиАй ЭЛЛЕБО, ИНК. (JP) Аппарат для ионтофореза, доставляющий множество активных агентов к биологическим барьерам
US20070074590A1 (en) * 2005-09-30 2007-04-05 Transcutaneous Technologies Inc. Method and system to detect malfunctions in an iontophoresis device that delivers active agents to biological interfaces
US20090299265A1 (en) * 2005-09-30 2009-12-03 Tti Ellebeau, Inc. Electrode Assembly for Iontophoresis Having Shape-Memory Separator and Iontophoresis Device Using the Same
WO2007040938A1 (fr) * 2005-09-30 2007-04-12 Tti Ellebeau, Inc. Systemes, dispositifs et procedes d'apport de medicament transdermique a micro-aiguilles fonctionnalisees
WO2007041118A1 (fr) * 2005-09-30 2007-04-12 Tti Ellebeau, Inc. Dispositif d'iontophorese et methode d'administration d'agents actifs a une interface biologique
KR20080080087A (ko) * 2005-09-30 2008-09-02 티티아이 엘뷰 가부시키가이샤 신규 약학 담체를 이용한 경피 약물 전달시스템, 장치 및방법
US20070083185A1 (en) * 2005-09-30 2007-04-12 Darrick Carter Iontophoretic device and method of delivery of active agents to biological interface
WO2007041526A2 (fr) * 2005-09-30 2007-04-12 Transcutaneous Technologies Inc. Appareil de ionophorese et procede d'apport d'antibiotiques vers des interfaces biologiques
KR20080066712A (ko) * 2005-09-30 2008-07-16 티티아이 엘뷰 가부시키가이샤 관능화된 미세바늘 경피 약물 전달 시스템, 장치 및 방법
US20070135754A1 (en) * 2005-09-30 2007-06-14 Hidero Akiyama Electrode assembly for iontophoresis for administering active agent enclosed in nanoparticle and iontophoresis device using the same
JP2009509677A (ja) * 2005-09-30 2009-03-12 Ｔｔｉ・エルビュー株式会社 小胞封入活性物質のイオントフォレーシス送達
EP1944057A4 (fr) * 2005-09-30 2009-02-18 Tti Ellebeau Inc Appareil d'iontophorese capable de regler la dose et l'heure d'administration d'un inducteur de sommeil et d'un agent analeptique
US20070197955A1 (en) * 2005-10-12 2007-08-23 Transcutaneous Technologies Inc. Mucous membrane adhesion-type iontophoresis device
US20090221985A1 (en) * 2005-10-19 2009-09-03 Shmuel Bukshpan System for iontophoretic transdermal delivery of polymeric agents and methods of use thereof
US20070149916A1 (en) * 2005-12-22 2007-06-28 Alza Corporation Dry matrices as drug reservoirs in electrotransport applications
WO2007079116A1 (fr) * 2005-12-28 2007-07-12 Tti Ellebeau, Inc. Appareil de pompe électroosmotique et procédé pour acheminer des agents actifs à des interfaces biologiques
WO2007079190A2 (fr) * 2005-12-29 2007-07-12 Tti Ellebeau, Inc. Dispositif et procede renforçant la reponse immunitaire par stimulation electrique
US7848801B2 (en) * 2005-12-30 2010-12-07 Tti Ellebeau, Inc. Iontophoretic systems, devices, and methods of delivery of active agents to biological interface
JP2009528990A (ja) * 2006-02-13 2009-08-13 アヴィバ ドラッグ デリバリー システムズ スフェンタニルを含む接着性調製物およびそれを用いる方法
AU2007216966C1 (en) 2006-02-22 2014-03-20 Mannkind Corporation A method for improving the pharmaceutic properties of microparticles comprising diketopiperazine and an active agent
US20080004564A1 (en) * 2006-03-30 2008-01-03 Transcutaneous Technologies Inc. Controlled release membrane and methods of use
CN101528300A (zh) * 2006-09-05 2009-09-09 Tti优而美株式会社 使用感应电源的透皮药物输送系统、装置和方法
TW200838576A (en) * 2006-12-01 2008-10-01 Transcu Ltd Systems, devices and methods for powering and/or controlling transdermal delivery devices
US20080188791A1 (en) * 2007-02-02 2008-08-07 Difiore Attilio E Active iontophoresis delivery system
JP5489988B2 (ja) * 2007-05-18 2014-05-14 Ｔｔｉ・エルビュー株式会社 有効成分の生体界面への改善された放出を確保する経皮送達装置
US8197844B2 (en) * 2007-06-08 2012-06-12 Activatek, Inc. Active electrode for transdermal medicament administration
EP2644228A1 (fr) * 2007-06-27 2013-10-02 The General Hospital Corporation Procédé et appareil d'inhibition optique de thérapie photodynamique
US8862223B2 (en) 2008-01-18 2014-10-14 Activatek, Inc. Active transdermal medicament patch and circuit board for same
US8485180B2 (en) 2008-06-13 2013-07-16 Mannkind Corporation Dry powder drug delivery system
EP2570147B1 (fr) 2008-06-13 2017-10-18 MannKind Corporation Inhalateur de poudre sèche et système d'administration de médicament
EP2300083B1 (fr) 2008-06-20 2013-05-22 MannKind Corporation Appareil interactif pour l'établissement en temps réel d'un profil des efforts d'inhalation
TWI614024B (zh) 2008-08-11 2018-02-11 曼凱公司 超快起作用胰島素之用途
MX2011002529A (es) * 2008-09-10 2011-07-29 Transcu Ltd Aparato y metodo para suministrar liquidos viscosos basados en hpc dentro de substratos porosos, por ejemplo un proceso basado en una banda continua.
US8314106B2 (en) 2008-12-29 2012-11-20 Mannkind Corporation Substituted diketopiperazine analogs for use as drug delivery agents
EP2405963B1 (fr) 2009-03-11 2013-11-06 MannKind Corporation Appareil, système et procédé de mesure de résistance d'un inhalateur
WO2010144424A2 (fr) * 2009-06-09 2010-12-16 Tti Ellebeau, Inc. Electrode longue durée de grande capacité, dispositif et procédé de fabrication
KR20200028501A (ko) 2009-06-12 2020-03-16 맨카인드 코포레이션 한정된 비표면적을 갖는 디케토피페라진 마이크로입자
CA2778698A1 (fr) 2009-11-03 2011-05-12 Mannkind Corporation Appareil et methode de simulation d'efforts d'inhalation
WO2011130455A1 (fr) 2010-04-13 2011-10-20 Najib Babul Compositions pharmaceutiques dermiques de 1-méthyl-2',6'-pipécoloxylidide et méthode d'utilisation
KR20130117755A (ko) 2010-06-21 2013-10-28 맨카인드 코포레이션 건조 분말 약물 운반 시스템 및 방법
US9731121B2 (en) 2011-03-31 2017-08-15 Incline Therapeutics, Inc. Switch validation circuit and method
US8428708B1 (en) 2012-05-21 2013-04-23 Incline Therapeutics, Inc. Self-test for analgesic product
US8781571B2 (en) 2011-03-31 2014-07-15 Incline Therapeutics, Inc. Switch validation circuit and method
US8428709B1 (en) 2012-06-11 2013-04-23 Incline Therapeutics, Inc. Current control for electrotransport drug delivery
BR112013025395B1 (pt) 2011-04-01 2022-02-01 Mannkind Corporation Embalagem de bolha e método de fabricação de uma embalagem de bolhas
WO2012174472A1 (fr) 2011-06-17 2012-12-20 Mannkind Corporation Microparticules de dicétopipérazine de capacité élevée
WO2013063160A1 (fr) 2011-10-24 2013-05-02 Mannkind Corporation Procédés et compositions pour traiter la douleur
RU2650035C2 (ru) 2012-07-12 2018-04-06 Маннкайнд Корпорейшн Системы и способы доставки сухих порошковых лекарств
WO2014055110A1 (fr) † 2012-10-01 2014-04-10 United Technologies Corporation Aube directrice statique à canaux internes creux
EP2911690A1 (fr) 2012-10-26 2015-09-02 MannKind Corporation Compositions et procédés de vaccin antigrippal inhalable
CN108578372B (zh) 2013-03-15 2021-07-06 曼金德公司 微晶二酮哌嗪组合物以及方法
WO2015010092A1 (fr) 2013-07-18 2015-01-22 Mannkind Corporation Compositions pharmaceutiques en poudre sèche stables à la chaleur et procédés
US11446127B2 (en) 2013-08-05 2022-09-20 Mannkind Corporation Insufflation apparatus and methods
US10307464B2 (en) 2014-03-28 2019-06-04 Mannkind Corporation Use of ultrarapid acting insulin
US10561806B2 (en) 2014-10-02 2020-02-18 Mannkind Corporation Mouthpiece cover for an inhaler
CN104353183B (zh) * 2014-10-31 2016-12-07 厦门微科格瑞生物科技有限公司 电解液位置固定的可佩戴智能药物导入结构
US12102508B2 (en) * 2016-10-21 2024-10-01 Ohio State Innovation Foundation Antimicrobial wound care dressing
KR20190003316A (ko) * 2017-06-30 2019-01-09 주식회사 엑소코바이오 지방줄기세포 유래의 엑소좀 및/또는 세포외 소포체를 유효성분으로 포함하는 조성물의 피부염 개선 용도
KR102649069B1 (ko) * 2018-05-31 2024-03-19 주식회사 엑소코바이오 줄기세포 유래의 엑소좀을 유효성분으로 포함하는 안면 홍조 개선용 조성물
CN110693857B (zh) * 2019-10-17 2023-08-11 宜昌人福药业有限责任公司 一种舒芬太尼透皮贴剂及其制备方法

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE410009C (de) * 1923-12-25 1925-02-21 Willi Reiche Dipl Ing Sprungwellenschutz fuer die Induktionswicklungen elektrischer Apparate und Maschinen
US3598123A (en) * 1969-04-01 1971-08-10 Alza Corp Bandage for administering drugs
US3598122A (en) * 1969-04-01 1971-08-10 Alza Corp Bandage for administering drugs
US3991755A (en) * 1973-07-27 1976-11-16 Medicon, Inc. Iontophoresis apparatus for applying local anesthetics
US4144317A (en) * 1975-05-30 1979-03-13 Alza Corporation Device consisting of copolymer having acetoxy groups for delivering drugs
US4141359A (en) * 1976-08-16 1979-02-27 University Of Utah Epidermal iontophoresis device
US4250878A (en) * 1978-11-22 1981-02-17 Motion Control, Inc. Non-invasive chemical species delivery apparatus and method
BR8008859A (pt) * 1979-10-10 1981-08-25 Cyclotech Med Ind Bandagem bloqueadora de dor
US4286592A (en) * 1980-02-04 1981-09-01 Alza Corporation Therapeutic system for administering drugs to the skin
US4314557A (en) * 1980-05-19 1982-02-09 Alza Corporation Dissolution controlled active agent dispenser
US4383529A (en) * 1980-11-03 1983-05-17 Wescor, Inc. Iontophoretic electrode device, method and gel insert
US4379454A (en) * 1981-02-17 1983-04-12 Alza Corporation Dosage for coadministering drug and percutaneous absorption enhancer
JPS5810066A (ja) * 1981-07-10 1983-01-20 株式会社アドバンス イオントフオレ−ゼ用プラスタ−構造体
US4640689A (en) * 1983-08-18 1987-02-03 Drug Delivery Systems Inc. Transdermal drug applicator and electrodes therefor
US4808152A (en) * 1983-08-18 1989-02-28 Drug Delivery Systems Inc. System and method for controlling rate of electrokinetic delivery of a drug
US4568343A (en) * 1984-10-09 1986-02-04 Alza Corporation Skin permeation enhancer compositions
US4747819A (en) * 1984-10-29 1988-05-31 Medtronic, Inc. Iontophoretic drug delivery
US4744787A (en) * 1984-10-29 1988-05-17 Medtronic, Inc. Iontophoresis apparatus and methods of producing same
US4702732A (en) * 1984-12-24 1987-10-27 Trustees Of Boston University Electrodes, electrode assemblies, methods, and systems for tissue stimulation and transdermal delivery of pharmacologically active ligands
US4722726A (en) * 1986-02-12 1988-02-02 Key Pharmaceuticals, Inc. Method and apparatus for iontophoretic drug delivery
US4752285B1 (en) * 1986-03-19 1995-08-22 Univ Utah Res Found Methods and apparatus for iontophoresis application of medicaments
US4731049A (en) * 1987-01-30 1988-03-15 Ionics, Incorporated Cell for electrically controlled transdermal drug delivery

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WO1993001807A1 (fr) 1993-02-04
ES2076779T3 (es) 1995-11-01
EP0596036A1 (fr) 1994-05-11
IE922372A1 (en) 1993-01-27
ZA925513B (en) 1993-08-03
AU2426792A (en) 1993-02-23
PT100720A (pt) 1994-05-31
IE71032B1 (en) 1997-01-15
ATE127340T1 (de) 1995-09-15
JPH06509254A (ja) 1994-10-20
EP0596036B1 (fr) 1995-09-06
DE69204676T2 (de) 1996-02-08
MX9204304A (es) 1993-01-01
DE69204676D1 (de) 1995-10-12
GR3017333T3 (en) 1995-12-31
US5203768A (en) 1993-04-20

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