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CA2413582A1 - Methode de traitement de l'infection - Google Patents

Methode de traitement de l'infection Download PDF

Info

Publication number
CA2413582A1
CA2413582A1 CA002413582A CA2413582A CA2413582A1 CA 2413582 A1 CA2413582 A1 CA 2413582A1 CA 002413582 A CA002413582 A CA 002413582A CA 2413582 A CA2413582 A CA 2413582A CA 2413582 A1 CA2413582 A1 CA 2413582A1
Authority
CA
Canada
Prior art keywords
methyl
oxyacetic acid
compound
benzyl
carbamoylcarbazol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002413582A
Other languages
English (en)
Inventor
Andrew Loh
Simona Skerjanec
William Louis Macias
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2413582A1 publication Critical patent/CA2413582A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/02—Local antiseptics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Indole Compounds (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
  • Food Preservation Except Freezing, Refrigeration, And Drying (AREA)
  • Apparatuses For Bulk Treatment Of Fruits And Vegetables And Apparatuses For Preparing Feeds (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)

Abstract

Cette invention concerne une méthode de traitement et/ou de prévention de l'infection.
CA002413582A 2000-07-14 2001-06-29 Methode de traitement de l'infection Abandoned CA2413582A1 (fr)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US21892800P 2000-07-14 2000-07-14
US60/218,928 2000-07-14
US25639800P 2000-12-18 2000-12-18
US60/256,398 2000-12-18
PCT/US2001/016509 WO2002005796A2 (fr) 2000-07-14 2001-06-29 Methode de traitement de l'infection

Publications (1)

Publication Number Publication Date
CA2413582A1 true CA2413582A1 (fr) 2002-01-24

Family

ID=26913393

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002413582A Abandoned CA2413582A1 (fr) 2000-07-14 2001-06-29 Methode de traitement de l'infection

Country Status (7)

Country Link
EP (1) EP1303262A2 (fr)
JP (1) JP2004503586A (fr)
CN (1) CN1450893A (fr)
AU (1) AU2001272915A1 (fr)
BR (1) BR0112460A (fr)
CA (1) CA2413582A1 (fr)
WO (1) WO2002005796A2 (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5584518B2 (ja) 2009-05-28 2014-09-03 石原産業株式会社 ジアミノトリフルオロメチルピリジン誘導体を含有する抗ショック剤
EP3693063A1 (fr) * 2019-02-06 2020-08-12 Diaccurate Procédés et compositions de traitement du cancer
CN112022846B (zh) * 2020-09-23 2021-10-08 吕奔 一种吲哚啉衍生物在制备治疗脓毒症药物中的应用
CN119158697B (zh) * 2024-11-21 2025-03-04 烟台铁口机床辅机有限公司 一种金属切屑用切削油的回收装置

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL109311A0 (en) * 1993-04-16 1994-07-31 Lilly Co Eli 1H-indole-3-acetamide sPla2 inhibitors
IL109309A (en) * 1993-04-16 2000-06-29 Lilly Co Eli 1-H-indole-3-acetic acid hydrazide SPLA2 inhibitors and pharmaceutical compositions containing them
PT675110E (pt) * 1994-04-01 2002-11-29 Lilly Co Eli 1h-indole-3-glioxilamidas inibidoras da spla2
US5641800A (en) * 1994-07-21 1997-06-24 Eli Lilly And Company 1H-indole-1-functional sPLA2 inhibitors
CA2264020A1 (fr) * 1996-08-26 1998-03-05 Jean Bemis Inhibiteurs des enzymes phospholipases
CA2279211A1 (fr) * 1997-02-20 1998-08-27 Shionogi & Co., Ltd. Derives d'acide indoldicarboxylique
AU1279899A (en) * 1997-10-27 1999-05-17 Eli Lilly And Company N,n-diethylglycolamido ester prodrugs of indole spla2 inhibitors
US6177426B1 (en) * 1997-10-27 2001-01-23 Eli Lilly And Company Morpholino-N-ethyl ester prodrugs of indole sPLA2 inhibitors
AU1200799A (en) * 1997-10-27 1999-05-17 Eli Lilly And Company Isopropyl ester prodrugs of indole spla2 inhibitors
PL342516A1 (en) * 1998-02-25 2001-06-18 Genetics Inst Phospholipase a2 inhibitors
KR20010034552A (ko) * 1998-03-03 2001-04-25 요시히코 시오노 포스포리파제 저해제인 소듐[[3-(2-아미노-1,2-디옥소에틸)-2-에틸-1-(페닐메틸)-1ｈ-인돌-4-일]옥시]아세테이트를 포함하는 약학적 조성물
ID23219A (id) * 1998-04-17 2000-03-30 Lilly Co Eli Trisiklik tersubstitusi
DZ2769A1 (fr) * 1998-04-17 2003-12-01 Lilly Co Eli Composés tricycliques substitués.
ATE280155T1 (de) * 1998-05-01 2004-11-15 Lilly Co Eli Inhibitorische ester für spla 2
WO2000007591A1 (fr) * 1998-08-03 2000-02-17 Eli Lilly And Company INHIBITEURS DE sPLA2 DE TYPE INDOLE
WO2000007590A1 (fr) * 1998-08-03 2000-02-17 Eli Lilly And Company INHIBITEURS DE sPLA2 DE TYPE INDOLE
AU1940800A (en) * 1998-12-21 2000-07-12 Eli Lilly And Company Combination therapy for the treatment of sepsis
US6391908B1 (en) * 1998-12-22 2002-05-21 Eli Lilly And Company Oxime amide indole type sPLA2 inhibitors

Also Published As

Publication number Publication date
EP1303262A2 (fr) 2003-04-23
AU2001272915A1 (en) 2002-01-30
BR0112460A (pt) 2003-07-22
CN1450893A (zh) 2003-10-22
JP2004503586A (ja) 2004-02-05
WO2002005796A2 (fr) 2002-01-24
WO2002005796A3 (fr) 2002-09-06

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