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AU2002361160B2 - Purified Hepatitis C virus envelope proteins for diagnostic and therapeutic use - Google Patents

Purified Hepatitis C virus envelope proteins for diagnostic and therapeutic use Download PDF

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Publication number
AU2002361160B2
AU2002361160B2 AU2002361160A AU2002361160A AU2002361160B2 AU 2002361160 B2 AU2002361160 B2 AU 2002361160B2 AU 2002361160 A AU2002361160 A AU 2002361160A AU 2002361160 A AU2002361160 A AU 2002361160A AU 2002361160 B2 AU2002361160 B2 AU 2002361160B2
Authority
AU
Australia
Prior art keywords
hcv
therapeutic
antigen
protein
seq
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
AU2002361160A
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English (en)
Other versions
AU2002361160A1 (en
Inventor
Fons Bosman
Erik Depla
Geert Maertens
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GenImmune NV
Original Assignee
GenImmune NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by GenImmune NV filed Critical GenImmune NV
Publication of AU2002361160A1 publication Critical patent/AU2002361160A1/en
Assigned to GENIMMUNE N.V. reassignment GENIMMUNE N.V. Request for Assignment Assignors: INNOGENETICS N.V.
Application granted granted Critical
Publication of AU2002361160B2 publication Critical patent/AU2002361160B2/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • A61K39/29Hepatitis virus
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C07K14/08RNA viruses
    • C07K14/18Togaviridae; Flaviviridae
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011Details
    • C12N2770/24011Flaviviridae
    • C12N2770/24211Hepacivirus, e.g. hepatitis C virus, hepatitis G virus
    • C12N2770/24222New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Oncology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AU2002361160A 2001-12-18 2002-12-18 Purified Hepatitis C virus envelope proteins for diagnostic and therapeutic use Expired - Fee Related AU2002361160B2 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US2051001A 2001-12-18 2001-12-18
US10/020,510 2001-12-18
US41835802P 2002-10-16 2002-10-16
US60/418,358 2002-10-16
PCT/EP2002/014480 WO2003051912A2 (fr) 2001-12-18 2002-12-18 Proteines purifiees du virus de l'hepatite c utilisables en diagnostic et therapie

Publications (2)

Publication Number Publication Date
AU2002361160A1 AU2002361160A1 (en) 2003-06-30
AU2002361160B2 true AU2002361160B2 (en) 2008-07-03

Family

ID=26693530

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2002361160A Expired - Fee Related AU2002361160B2 (en) 2001-12-18 2002-12-18 Purified Hepatitis C virus envelope proteins for diagnostic and therapeutic use

Country Status (12)

Country Link
EP (1) EP1461080A2 (fr)
JP (1) JP2005516939A (fr)
KR (1) KR20040076869A (fr)
CN (1) CN1622828A (fr)
AU (1) AU2002361160B2 (fr)
BR (1) BR0215081A (fr)
CA (1) CA2468690A1 (fr)
IL (1) IL162236A0 (fr)
MX (1) MXPA04005891A (fr)
NZ (1) NZ533396A (fr)
RU (1) RU2319505C2 (fr)
WO (1) WO2003051912A2 (fr)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7108855B2 (en) 1998-06-24 2006-09-19 Innogenetics N.V. Purified hepatitis C virus envelope proteins for diagnostic and therapeutic use
US7101561B2 (en) 2000-12-01 2006-09-05 Innogenetics N.V. Purified hepatitis C virus envelope proteins for diagnostic and therapeutic use
EP1414942A2 (fr) 2001-04-24 2004-05-06 Innogenetics N.V. Expression, dans la levure, de proteines de l'enveloppe du virus de l'hepatite c (vhc) a nucleo-glycosylation
FR2859221B1 (fr) * 2003-08-28 2005-10-14 Centre Nat Rech Scient Vecteur de co-expression de domaines membranaires de proteines d'enveloppe d'un virus et utilisations
EP1574517A1 (fr) 2004-03-09 2005-09-14 Innogenetics N.V. HCV E1 contenant les ponts disulfure spécifiques
EP1809773B1 (fr) * 2004-10-18 2014-07-16 Globeimmune, Inc. Moyens therapeutiques a base de levure contre l'infection par hepatite c chronique
CN100365124C (zh) * 2005-10-27 2008-01-30 云南大学 一段丙型肝炎病毒特异性cDNA序列的应用
WO2009030872A1 (fr) * 2007-09-07 2009-03-12 Mats Axel Atterdag Persson Matériaux et procédés pour le traitement de l'hépatite c
DK2285408T3 (en) 2008-06-05 2019-02-04 Ablynx Nv AMINO ACID SEQUENCES AGAINST COATING PROTEINS IN A VIRUS AND POLYPEPTIDES INCLUDING THESE FOR TREATMENT OF VIRUSAL DISEASES
RU2016103067A (ru) 2009-06-05 2018-11-20 Аблинкс Нв Улучшенные аминокислотные последовательности, направленные против респираторно-синцитиального вируса человека (hrsv), и полипептиды, включающие такие последовательности, для профилактики и/или лечения инфекций дыхательных путей
EP2507262A1 (fr) 2009-11-30 2012-10-10 Ablynx N.V. Séquences d'acides aminés améliorées dirigées contre le virus syncytial respiratoire humain (hrsv) et polypeptides comprenant celles-ci pour la prévention et/ou le traitement d'infections du tractus respiratoire
SG195383A1 (en) 2011-06-14 2013-12-30 Globeimmune Inc Yeast-based compositions and methods for the treatment or prevention of hepatitis delta virus infection
RU2570553C2 (ru) * 2013-11-20 2015-12-10 Федеральное бюджетное учреждение "Всероссийский научно-исследовательский институт лесоводства и механизации лесного хозяйства (ФБУ ВНИИЛМ) Способ очистки вирусных полиэдров
CN104327170A (zh) * 2014-05-16 2015-02-04 中国疾病预防控制中心病毒病预防控制所 丙型肝炎病毒(hcv)细胞进入抑制肽zte1序列及应用
CA2961568A1 (fr) 2014-09-17 2016-03-24 The University Of Iowa Research Foundation Segments d'arn viral utilises en tant qu'agents immunomodulateurs et composants de vaccin
AU2017334263B2 (en) * 2016-09-29 2024-11-28 Macfarlane Burnet Institute For Medical Research And Public Health Limited Assembled glycoproteins
WO2020117760A1 (fr) * 2018-12-03 2020-06-11 Duke University Procédé de purification de nanoparticules et de protéines recombinantes

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6555114B1 (en) * 1993-11-04 2003-04-29 Innogenetics N.V. Immunodominant human T-cell epitopes of hepatitis C virus
JP2002518037A (ja) * 1998-06-24 2002-06-25 イノジェネティックス・ナムローゼ・フェンノートシャップ Hcvエンベロープ蛋白の粒子:ワクチン接種への使用

Also Published As

Publication number Publication date
AU2002361160A1 (en) 2003-06-30
CA2468690A1 (fr) 2003-06-26
KR20040076869A (ko) 2004-09-03
EP1461080A2 (fr) 2004-09-29
WO2003051912A3 (fr) 2004-03-04
RU2319505C2 (ru) 2008-03-20
MXPA04005891A (es) 2004-09-13
JP2005516939A (ja) 2005-06-09
WO2003051912A9 (fr) 2004-07-15
WO2003051912A2 (fr) 2003-06-26
NZ533396A (en) 2005-04-29
RU2004116914A (ru) 2005-04-20
IL162236A0 (en) 2005-11-20
CN1622828A (zh) 2005-06-01
BR0215081A (pt) 2004-10-19

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PC1 Assignment before grant (sect. 113)

Owner name: GENIMMUNE N.V.

Free format text: FORMER APPLICANT(S): INNOGENETICS N.V.

MK25 Application lapsed reg. 22.2i(2) - failure to pay acceptance fee
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