AU2001273847A1 - Polydesoxyribonucleotides for inhibiting the expression of the icam-1-gene - Google Patents
Polydesoxyribonucleotides for inhibiting the expression of the icam-1-geneInfo
- Publication number
- AU2001273847A1 AU2001273847A1 AU2001273847A AU7384701A AU2001273847A1 AU 2001273847 A1 AU2001273847 A1 AU 2001273847A1 AU 2001273847 A AU2001273847 A AU 2001273847A AU 7384701 A AU7384701 A AU 7384701A AU 2001273847 A1 AU2001273847 A1 AU 2001273847A1
- Authority
- AU
- Australia
- Prior art keywords
- polydesoxyribonucleotides
- icam
- inhibiting
- gene
- expression
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 230000002401 inhibitory effect Effects 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
- C12N15/1138—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against receptors or cell surface proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/15—Nucleic acids forming more than 2 strands, e.g. TFOs
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/30—Chemical structure
- C12N2310/31—Chemical structure of the backbone
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/30—Chemical structure
- C12N2310/32—Chemical structure of the sugar
- C12N2310/321—2'-O-R Modification
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/30—Chemical structure
- C12N2310/35—Nature of the modification
- C12N2310/351—Conjugate
- C12N2310/3511—Conjugate intercalating or cleaving agent
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Pulmonology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Molecular Biology (AREA)
- Plant Pathology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Immunology (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE10019252A DE10019252A1 (en) | 2000-04-18 | 2000-04-18 | Polydeoxyribonucleotides to inhibit ICAM-1 gene expression |
DE10019252 | 2000-04-18 | ||
PCT/DE2001/001509 WO2001079487A2 (en) | 2000-04-18 | 2001-04-18 | Polydesoxyribonucleotides for inhibiting the expression of the icam-1-gene |
Publications (1)
Publication Number | Publication Date |
---|---|
AU2001273847A1 true AU2001273847A1 (en) | 2001-10-30 |
Family
ID=7639214
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU2001273847A Abandoned AU2001273847A1 (en) | 2000-04-18 | 2001-04-18 | Polydesoxyribonucleotides for inhibiting the expression of the icam-1-gene |
Country Status (3)
Country | Link |
---|---|
AU (1) | AU2001273847A1 (en) |
DE (1) | DE10019252A1 (en) |
WO (1) | WO2001079487A2 (en) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ITUB20155754A1 (en) * | 2015-11-20 | 2017-05-20 | Mastelli S R L | Composition for the treatment of intestinal inflammatory diseases. |
Family Cites Families (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU3056889A (en) * | 1988-01-21 | 1989-08-11 | Yale University | Selective inhibition of gene expression by photoactivatable oligonucleotides |
US6096722A (en) * | 1990-08-14 | 2000-08-01 | Isis Pharmaceuticals Inc. | Antisense modulation of cell adhesion molecule expression and treatment of cell adhesion molecule-associated diseases |
US6111094A (en) * | 1990-08-14 | 2000-08-29 | Isis Pharmaceuticals Inc. | Enhanced antisense modulation of ICAM-1 |
ATE230023T1 (en) * | 1990-08-14 | 2003-01-15 | Isis Pharmaceuticals Inc | INFLUENCE ON CELL ADHESION BY OLIGONUCLEOTIDES |
US5789573A (en) * | 1990-08-14 | 1998-08-04 | Isis Pharmaceuticals, Inc. | Antisense inhibition of ICAM-1, E-selectin, and CMV IE1/IE2 |
AU3598293A (en) * | 1992-01-31 | 1993-09-01 | Regents Of The University Of California, The | Method for making universal donor cells |
US5580969A (en) * | 1992-07-24 | 1996-12-03 | The United States Of America As Represented By The Secretary Of The Navy | Antisense oligonucleotides directed against human ICAM-I RNA |
HUT69922A (en) * | 1992-09-02 | 1995-09-28 | Isis Pharmaceuticals Inc | Oligonucleotide modification of cell adhesion |
AU7559894A (en) * | 1993-08-05 | 1995-02-28 | Isis Pharmaceuticals, Inc. | Oligomers for modulating metabolic function |
US5696248A (en) * | 1994-06-15 | 1997-12-09 | Hoechst Aktiengesellschaft | 3'-modified oligonucleotide derivatives |
WO1996015780A1 (en) * | 1994-11-23 | 1996-05-30 | Isis Pharmaceuticals, Inc. | Compositions and methods for preventing and treating allograft rejection |
WO1998024797A1 (en) * | 1996-12-02 | 1998-06-11 | Dyad Pharmaceutical Corporation | Antisense inhibition of human adhesion molecules |
US6277967B1 (en) * | 1998-07-14 | 2001-08-21 | Isis Pharmaceuticals, Inc. | Carbohydrate or 2′-modified oligonucleotides having alternating internucleoside linkages |
CN1317009A (en) * | 1998-08-03 | 2001-10-10 | 东卡罗来纳大学 | Low adenosine anti-sense oligonucleotide agent, composition, reagent kit and treatments |
US6114517A (en) * | 1998-12-10 | 2000-09-05 | Isis Pharmaceuticals Inc. | Methods of modulating tumor necrosis factor α-induced expression of cell adhesion molecules |
WO2001029262A2 (en) * | 1999-10-15 | 2001-04-26 | Orchid Biosciences, Inc. | Genotyping reagents, kits and methods of use thereof |
-
2000
- 2000-04-18 DE DE10019252A patent/DE10019252A1/en not_active Withdrawn
-
2001
- 2001-04-18 WO PCT/DE2001/001509 patent/WO2001079487A2/en active Application Filing
- 2001-04-18 AU AU2001273847A patent/AU2001273847A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
WO2001079487A3 (en) | 2002-06-20 |
WO2001079487A2 (en) | 2001-10-25 |
DE10019252A1 (en) | 2001-10-31 |
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