AU2001268007A1 - Novel cytotoxic compounds and their use - Google Patents

Novel cytotoxic compounds and their use

Info

Publication number: AU2001268007A1
Authority: AU; Australia
Prior art keywords: cysteamine; phospho; aminoethanol; phosphate; linolenoyl
Prior art date: 2000-07-12
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Abandoned

Application number

AU2001268007A

Other languages

English (en)

Inventor

Oleg Strelchenok

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Ardenia Investments Ltd

Original Assignee

Ardenia Investments Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-07-12

Filing date

2001-07-05

Publication date

2002-01-21

2000-07-12 Priority claimed from SE0002629A external-priority patent/SE0002629D0/xx

2001-07-05 Application filed by Ardenia Investments Ltd filed Critical Ardenia Investments Ltd

2002-01-21 Publication of AU2001268007A1 publication Critical patent/AU2001268007A1/en

Status Abandoned legal-status Critical Current

Links

150000001875 compounds Chemical class 0.000 title 1
231100000433 cytotoxic Toxicity 0.000 title 1
230000001472 cytotoxic effect Effects 0.000 title 1
150000001408 amides Chemical class 0.000 abstract 2
OSXDKPMVQBAQNA-UHFFFAOYSA-N 2-(docosa-2,4,6,8,10,12-hexaenoyloxyamino)ethoxy-oxido-oxophosphanium Chemical compound C(C=CC=CC=CC=CC=CC=CCCCCCCCCC)(=O)ONCCOP(=O)=O OSXDKPMVQBAQNA-UHFFFAOYSA-N 0.000 abstract 1
JAVWBHAJWQRZDD-UHFFFAOYSA-N 2-(icosa-2,4,6,8,10-pentaenoyloxyamino)ethoxy-oxido-oxophosphanium Chemical compound C(C=CC=CC=CC=CC=CCCCCCCCCC)(=O)ONCCOP(=O)=O JAVWBHAJWQRZDD-UHFFFAOYSA-N 0.000 abstract 1
DXXJDTSNRNNWHQ-DOFZRALJSA-N 2-[[(5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoyl]oxyamino]ethoxy-oxido-oxophosphanium Chemical compound C(CCC\C=C/C\C=C/C\C=C/C\C=C/CCCCC)(=O)ONCCOP(=O)=O DXXJDTSNRNNWHQ-DOFZRALJSA-N 0.000 abstract 1
LZJUKIQAXWBZFI-QNEBEIHSSA-N 2-[[(6Z,9Z,12Z)-octadeca-6,9,12-trienoyl]oxyamino]ethoxy-oxido-oxophosphanium Chemical compound C(CCCC\C=C/C\C=C/C\C=C/CCCCC)(=O)ONCCOP(=O)=O LZJUKIQAXWBZFI-QNEBEIHSSA-N 0.000 abstract 1
JUMALYVMTSKVLY-PDBXOOCHSA-N 2-[[(9Z,12Z,15Z)-octadeca-9,12,15-trienoyl]oxyamino]ethoxy-oxido-oxophosphanium Chemical compound C(CCCCCCC\C=C/C\C=C/C\C=C/CC)(=O)ONCCOP(=O)=O JUMALYVMTSKVLY-PDBXOOCHSA-N 0.000 abstract 1
SHGAZHPCJJPHSC-NUEINMDLSA-N Isotretinoin Chemical compound OC(=O)C=C(C)/C=C/C=C(C)C=CC1=C(C)CCCC1(C)C SHGAZHPCJJPHSC-NUEINMDLSA-N 0.000 abstract 1
SHGAZHPCJJPHSC-YCNIQYBTSA-N all-trans-retinoic acid Chemical compound OC(=O)\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C SHGAZHPCJJPHSC-YCNIQYBTSA-N 0.000 abstract 1
230000000259 anti-tumor effect Effects 0.000 abstract 1
230000010261 cell growth Effects 0.000 abstract 1
RZPNFYXFSHGGBE-UHFFFAOYSA-N cysteamine S-phosphate Chemical compound NCCSP(O)(O)=O RZPNFYXFSHGGBE-UHFFFAOYSA-N 0.000 abstract 1
230000002401 inhibitory effect Effects 0.000 abstract 1
229960005280 isotretinoin Drugs 0.000 abstract 1
239000000203 mixture Substances 0.000 abstract 1
DCWXELXMIBXGTH-QMMMGPOBSA-N phosphonotyrosine Chemical compound OC(=O)[C@@H](N)CC1=CC=C(OP(O)(O)=O)C=C1 DCWXELXMIBXGTH-QMMMGPOBSA-N 0.000 abstract 1
235000020777 polyunsaturated fatty acids Nutrition 0.000 abstract 1
229930002330 retinoic acid Natural products 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/06—Phosphorus compounds without P—C bonds
- C07F9/08—Esters of oxyacids of phosphorus
- C07F9/09—Esters of phosphoric acids
- C07F9/091—Esters of phosphoric acids with hydroxyalkyl compounds with further substituents on alkyl
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/661—Phosphorus acids or esters thereof not having P—C bonds, e.g. fosfosal, dichlorvos, malathion or mevinphos
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/06—Phosphorus compounds without P—C bonds
- C07F9/08—Esters of oxyacids of phosphorus
- C07F9/09—Esters of phosphoric acids
- C07F9/12—Esters of phosphoric acids with hydroxyaryl compounds
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/06—Phosphorus compounds without P—C bonds
- C07F9/16—Esters of thiophosphoric acids or thiophosphorous acids
- C07F9/165—Esters of thiophosphoric acids
- C07F9/1651—Esters of thiophosphoric acids with hydroxyalkyl compounds with further substituents on alkyl

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Molecular Biology (AREA)
Biochemistry (AREA)
Epidemiology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Medicinal Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Saccharide Compounds (AREA)

AU2001268007A 2000-07-12 2001-07-05 Novel cytotoxic compounds and their use Abandoned AU2001268007A1 (en)

Applications Claiming Priority (5)

Application Number	Priority Date	Filing Date	Title
US21781000P	2000-07-12	2000-07-12
SE0002629		2000-07-12
US60217810		2000-07-12
SE0002629A SE0002629D0 (sv)	2000-07-12	2000-07-12	Novel compounds and their use
PCT/SE2001/001559 WO2002004467A1 (fr)	2000-07-12	2001-07-05	Nouveaux composes cytotoxiques et leur utilisation

Publications (1)

Publication Number	Publication Date
AU2001268007A1 true AU2001268007A1 (en)	2002-01-21

Family

ID=26655180

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AU2001268007A Abandoned AU2001268007A1 (en)	2000-07-12	2001-07-05	Novel cytotoxic compounds and their use

Country Status (7)

Country	Link
US (1)	US6699851B2 (fr)
EP (1)	EP1299400B1 (fr)
AT (1)	ATE339429T1 (fr)
AU (1)	AU2001268007A1 (fr)
DE (1)	DE60123058T2 (fr)
ES (1)	ES2272490T3 (fr)
WO (1)	WO2002004467A1 (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
BR112012031194A2 (pt) *	2010-06-08	2018-05-29	Krisani Biosciences P Ltd	derivados de cisteamina e seu uso no tratamento de ehna
WO2014045293A1 (fr) *	2012-09-24	2014-03-27	Krisani Bioscience (P) Ltd.	Amides d'acides gras comportant un groupe cystéamine ou un groupe cystéamine acétylé et leurs utilisations
WO2020169822A1 (fr) *	2019-02-21	2020-08-27	Universite Claude Bernard Lyon 1	Vecteurs moléculaires structurés pour des composés anti-inflammatoires et leurs utilisations

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
SE9802162D0 (sv) *	1998-06-17	1998-06-17	Nomet Management Services Bv	Immunostimulating composition
SE9900941D0 (sv) *	1998-12-23	1999-03-16	Nomet Management Serv Bv	Novel retinoic acid derivatives and their use
CN1149219C (zh) *	1999-03-11	2004-05-12	阿登尼亚投资有限公司	治疗癌症的新化合物

2001
- 2001-07-05 EP EP01945899A patent/EP1299400B1/fr not_active Expired - Lifetime
- 2001-07-05 DE DE60123058T patent/DE60123058T2/de not_active Expired - Lifetime
- 2001-07-05 US US10/332,745 patent/US6699851B2/en not_active Expired - Lifetime
- 2001-07-05 ES ES01945899T patent/ES2272490T3/es not_active Expired - Lifetime
- 2001-07-05 AU AU2001268007A patent/AU2001268007A1/en not_active Abandoned
- 2001-07-05 WO PCT/SE2001/001559 patent/WO2002004467A1/fr active IP Right Grant
- 2001-07-05 AT AT01945899T patent/ATE339429T1/de active

Also Published As

Publication number	Publication date
US6699851B2 (en)	2004-03-02
EP1299400B1 (fr)	2006-09-13
ATE339429T1 (de)	2006-10-15
EP1299400A1 (fr)	2003-04-09
US20030171338A1 (en)	2003-09-11
DE60123058T2 (de)	2007-04-05
WO2002004467A1 (fr)	2002-01-17
ES2272490T3 (es)	2007-05-01
DE60123058D1 (de)	2006-10-26

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