AU2001267844A1 - Method of preparing heart muscle cells and method of searching for remedy for heart diseases - Google Patents

Method of preparing heart muscle cells and method of searching for remedy for heart diseases

Info

Publication number: AU2001267844A1
Authority: AU; Australia
Prior art keywords: heart muscle; heart; muscle cells; cells; apoptosis
Prior art date: 2000-06-28
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Abandoned

Application number

AU2001267844A

Other languages

English (en)

Inventor

Hisao Hirota

Hideharu Kimura

Tadamitsu Kishimoto

Nobuyuki Koyama

Keiko Takihara

Seiichi Tanida

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Takeda Pharmaceutical Co Ltd

Original Assignee

Takeda Chemical Industries Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-06-28

Filing date

2001-06-27

Publication date

2002-01-08

2001-06-27 Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd

2002-01-08 Publication of AU2001267844A1 publication Critical patent/AU2001267844A1/en

Status Abandoned legal-status Critical Current

Links

210000004413 cardiac myocyte Anatomy 0.000 title abstract 8
238000000034 method Methods 0.000 title abstract 5
208000019622 heart disease Diseases 0.000 title abstract 2
230000006907 apoptotic process Effects 0.000 abstract 3
210000004027 cell Anatomy 0.000 abstract 2
210000005003 heart tissue Anatomy 0.000 abstract 2
210000004165 myocardium Anatomy 0.000 abstract 2
229940088872 Apoptosis inhibitor Drugs 0.000 abstract 1
229910019142 PO4 Inorganic materials 0.000 abstract 1
108091005804 Peptidases Proteins 0.000 abstract 1
239000004365 Protease Substances 0.000 abstract 1
102100037486 Reverse transcriptase/ribonuclease H Human genes 0.000 abstract 1
239000000158 apoptosis inhibitor Substances 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
239000003623 enhancer Substances 0.000 abstract 1
210000003743 erythrocyte Anatomy 0.000 abstract 1
239000001963 growth medium Substances 0.000 abstract 1
230000002949 hemolytic effect Effects 0.000 abstract 1
230000001939 inductive effect Effects 0.000 abstract 1
238000009630 liquid culture Methods 0.000 abstract 1
210000001161 mammalian embryo Anatomy 0.000 abstract 1
230000001404 mediated effect Effects 0.000 abstract 1
230000024244 muscle cell apoptotic process Effects 0.000 abstract 1
NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 abstract 1
239000010452 phosphate Substances 0.000 abstract 1
239000002504 physiological saline solution Substances 0.000 abstract 1
230000003449 preventive effect Effects 0.000 abstract 1
239000000018 receptor agonist Substances 0.000 abstract 1
229940044601 receptor agonist Drugs 0.000 abstract 1
210000002966 serum Anatomy 0.000 abstract 1
239000012679 serum free medium Substances 0.000 abstract 1
238000005406 washing Methods 0.000 abstract 1

Classifications

- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
- G01N33/5061—Muscle cells
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
- C12N5/0657—Cardiomyocytes; Heart cells
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2503/00—Use of cells in diagnostics
- C12N2503/02—Drug screening
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2509/00—Methods for the dissociation of cells, e.g. specific use of enzymes
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2510/00—Detection of programmed cell death, i.e. apoptosis
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/32—Cardiovascular disorders
- G01N2800/324—Coronary artery diseases, e.g. angina pectoris, myocardial infarction

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Biomedical Technology (AREA)
Chemical & Material Sciences (AREA)
Cell Biology (AREA)
Bioinformatics & Cheminformatics (AREA)
Immunology (AREA)
Biotechnology (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Microbiology (AREA)
Zoology (AREA)
Wood Science & Technology (AREA)
Biochemistry (AREA)
Urology & Nephrology (AREA)
Hematology (AREA)
Genetics & Genomics (AREA)
Molecular Biology (AREA)
Medicinal Chemistry (AREA)
Cardiology (AREA)
Tropical Medicine & Parasitology (AREA)
Toxicology (AREA)
General Engineering & Computer Science (AREA)
Food Science & Technology (AREA)
Rheumatology (AREA)
Physics & Mathematics (AREA)
Analytical Chemistry (AREA)
General Physics & Mathematics (AREA)
Pathology (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Heart & Thoracic Surgery (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Investigating Or Analysing Biological Materials (AREA)

AU2001267844A 2000-06-28 2001-06-27 Method of preparing heart muscle cells and method of searching for remedy for heart diseases Abandoned AU2001267844A1 (en)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
JP2000194805		2000-06-28
JP2000-194805		2000-06-28
PCT/JP2001/005520 WO2002000850A1 (fr)	2000-06-28	2001-06-27	Procede servant a preparer des cellules du muscle cardiaque et procede servant a rechercher des agents therapeutiques de maladies cardiaques

Publications (1)

Publication Number	Publication Date
AU2001267844A1 true AU2001267844A1 (en)	2002-01-08

Family

ID=18693571

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AU2001267844A Abandoned AU2001267844A1 (en)	2000-06-28	2001-06-27	Method of preparing heart muscle cells and method of searching for remedy for heart diseases

Country Status (6)

Country	Link
US (2)	US20030175847A1 (fr)
EP (2)	EP1295936B1 (fr)
AT (1)	ATE412766T1 (fr)
AU (1)	AU2001267844A1 (fr)
DE (1)	DE60136358D1 (fr)
WO (1)	WO2002000850A1 (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2004027014A1 (fr) *	2002-09-17	2004-04-01	Japan Tissue Engineering Co.,Ltd	Dispositif de dispersion de cellules, cassette de dispersion de cellules et partie retenue de tissu
US8168718B2 (en)	2005-12-09	2012-05-01	Exxonmobil Chemical Patents Inc.	Thermoplastic vulcanizate adhesive compositions
EP2226633A1 (fr) *	2009-03-06	2010-09-08	Charité - Universitätsmedizin Berlin	Utilisations et procédés d'identification d'un composé cytoprotecteur impliquant gp130 ou LIFRalpha
CN108949673A (zh) *	2018-08-13	2018-12-07	武汉华联科生物技术有限公司	一种大鼠胎鼠心肌细胞原代分离方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3948725A (en) *	1974-05-30	1976-04-06	Godo Shusei Kabushiki Kaisha	Neutral protease useful for animal tissue and cell culture
JPH0372872A (ja) *	1988-07-12	1991-03-28	Bio Kagaku Kenkyusho:Kk	無血清培地及びそれを用いた哺乳類細胞の培養法
US5543318A (en) *	1991-06-12	1996-08-06	Smith; David A.	Method of isolation, culture and proliferation of human atrial myocytes
US5378698A (en) *	1991-10-21	1995-01-03	Shionogi & Co., Ltd.	Benzothiazepine derivatives
US5919449A (en) *	1995-05-30	1999-07-06	Diacrin, Inc.	Porcine cardiomyocytes and their use in treatment of insufficient cardiac function
US6133233A (en) *	1997-02-18	2000-10-17	Kansas State University Research Foundation	Peptide modulation of reperfusion injury
WO1999011771A1 (fr) *	1997-09-04	1999-03-11	Science Research Laboratory, Inc.	Separation de cellules par utilisation de champs electriques
CA2306448A1 (fr) *	1997-10-16	1999-04-22	Board Of Regents, The University Of Texas System	Modeles et traitement de l'hypertrophie cardiaque en liaison avec la fonction nf-at3

2001
- 2001-06-27 AT AT01945643T patent/ATE412766T1/de not_active IP Right Cessation
- 2001-06-27 AU AU2001267844A patent/AU2001267844A1/en not_active Abandoned
- 2001-06-27 DE DE60136358T patent/DE60136358D1/de not_active Expired - Lifetime
- 2001-06-27 WO PCT/JP2001/005520 patent/WO2002000850A1/fr active Application Filing
- 2001-06-27 US US10/311,119 patent/US20030175847A1/en not_active Abandoned
- 2001-06-27 EP EP01945643A patent/EP1295936B1/fr not_active Expired - Lifetime
- 2001-06-27 EP EP08075845A patent/EP2090663A3/fr not_active Withdrawn
2008
- 2008-02-07 US US12/069,074 patent/US20080160553A1/en not_active Abandoned

Also Published As

Publication number	Publication date
WO2002000850A1 (fr)	2002-01-03
EP2090663A3 (fr)	2009-11-11
DE60136358D1 (de)	2008-12-11
EP1295936B1 (fr)	2008-10-29
EP2090663A2 (fr)	2009-08-19
EP1295936A1 (fr)	2003-03-26
ATE412766T1 (de)	2008-11-15
US20030175847A1 (en)	2003-09-18
US20080160553A1 (en)	2008-07-03
EP1295936A4 (fr)	2004-11-10

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