+

AU2000268170A1 - A cell line expressing mutant human tissue-type plasminogen activator, constructing strategy and method of expressed protein preparation - Google Patents

A cell line expressing mutant human tissue-type plasminogen activator, constructing strategy and method of expressed protein preparation

Info

Publication number
AU2000268170A1
AU2000268170A1 AU2000268170A AU6817000A AU2000268170A1 AU 2000268170 A1 AU2000268170 A1 AU 2000268170A1 AU 2000268170 A AU2000268170 A AU 2000268170A AU 6817000 A AU6817000 A AU 6817000A AU 2000268170 A1 AU2000268170 A1 AU 2000268170A1
Authority
AU
Australia
Prior art keywords
cell line
plasminogen activator
human tissue
expressed protein
protein preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2000268170A
Inventor
Jiahui Xia
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
HUNAN ROYAL BIOTECH
Original Assignee
HUNAN ROYAL BIOTECH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by HUNAN ROYAL BIOTECH filed Critical HUNAN ROYAL BIOTECH
Publication of AU2000268170A1 publication Critical patent/AU2000268170A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6456—Plasminogen activators
    • C12N9/6459—Plasminogen activators t-plasminogen activator (3.4.21.68), i.e. tPA
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21069—Protein C activated (3.4.21.69)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2291/00—Indexing codes associated with group G01N29/00
    • G01N2291/02—Indexing codes associated with the analysed material
    • G01N2291/025—Change of phase or condition
    • G01N2291/0256—Adsorption, desorption, surface mass change, e.g. on biosensors

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
AU2000268170A 2000-09-04 2000-09-04 A cell line expressing mutant human tissue-type plasminogen activator, constructing strategy and method of expressed protein preparation Abandoned AU2000268170A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/CN2000/000260 WO2002020802A1 (en) 2000-09-04 2000-09-04 A cell line expressing mutant human tissue-type plasminogen activator, constructing strategy and method of expressed protein preparation

Publications (1)

Publication Number Publication Date
AU2000268170A1 true AU2000268170A1 (en) 2002-03-22

Family

ID=4574691

Family Applications (2)

Application Number Title Priority Date Filing Date
AU2000268170A Abandoned AU2000268170A1 (en) 2000-09-04 2000-09-04 A cell line expressing mutant human tissue-type plasminogen activator, constructing strategy and method of expressed protein preparation
AU2001235320A Abandoned AU2001235320A1 (en) 2000-09-04 2001-02-16 A cell line expressing mutated human tissue - type plasminogen activator, the constructing strategy thereof and method of preparing expressed protein

Family Applications After (1)

Application Number Title Priority Date Filing Date
AU2001235320A Abandoned AU2001235320A1 (en) 2000-09-04 2001-02-16 A cell line expressing mutated human tissue - type plasminogen activator, the constructing strategy thereof and method of preparing expressed protein

Country Status (6)

Country Link
US (1) US7632677B2 (en)
EP (1) EP1323826A4 (en)
JP (1) JP2004508066A (en)
CN (1) CN1216149C (en)
AU (2) AU2000268170A1 (en)
WO (2) WO2002020802A1 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112111475B (en) * 2020-09-24 2021-07-20 江苏丰华生物制药有限公司 TNK-tPA fusion protein with enhanced transport capacity through epithelial cells and application thereof
CN112490602B (en) * 2020-10-19 2021-09-24 电子科技大学 THz guided wave regulation and control device based on multilayer structure

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2581652B1 (en) * 1985-04-22 1989-12-22 Genentech Inc NEW MUTANTS OF TISSUE ACTIVATOR OF HUMAN PLASMINOGEN
ES2031826T3 (en) * 1985-12-23 1993-01-01 Chiron Corporation PROCEDURE TO PRODUCE NEW PEPTIDE ACTIVATORS OF PLASMINOGEN.
PT86162B (en) * 1986-11-21 1990-11-20 Smithkline Beecham Corp RECOMBINANT PROTEIN EXPRESSION
EP0340573A3 (en) * 1988-04-30 1990-05-30 BASF Aktiengesellschaft Proteins, their production and their use
DE3927865A1 (en) * 1989-08-23 1991-02-28 Boehringer Mannheim Gmbh T-PA MUTANT GK1L
US5223408A (en) * 1991-07-11 1993-06-29 Genentech, Inc. Method for making variant secreted proteins with altered properties
US5795737A (en) * 1994-09-19 1998-08-18 The General Hospital Corporation High level expression of proteins
CN1113099C (en) 1996-10-26 2003-07-02 湖南医科大学 New carrier for gene treatment
WO2002010375A1 (en) * 2000-07-17 2002-02-07 Jiahui Xia Human source gene leading sequence, gene vector and gene expression strategy
CN1148228C (en) * 2000-08-30 2004-05-05 夏家辉 Gene medicine for treating hemophilia B and its preparing process

Also Published As

Publication number Publication date
AU2001235320A1 (en) 2002-03-26
EP1323826A1 (en) 2003-07-02
CN1216149C (en) 2005-08-24
US7632677B2 (en) 2009-12-15
WO2002020802A1 (en) 2002-03-14
EP1323826A4 (en) 2004-06-16
WO2002022832A1 (en) 2002-03-21
US20040077042A1 (en) 2004-04-22
JP2004508066A (en) 2004-03-18
CN1468310A (en) 2004-01-14

Similar Documents

Publication Publication Date Title
AU2001283492A1 (en) Methods of patterning protein and cell adhesivity
AU2001261160A1 (en) Prosthesis and method of making
AU2002356861A1 (en) Fibrin membrane and methods for its preparation- application to artificial skin
AU2001267075A1 (en) Disintegrating stent and method of making same
AU2002213838A1 (en) Method of producing non-bovine chymosin and use thereof
AU2001247263A1 (en) Memory cell, method of formation, and operation
AU2001268970A1 (en) Method for making a bipolar membrane and use of resulting bipolar membrane
AU4115501A (en) Disposable trunks-type shorts and production method therefor
AU2001261759A1 (en) Method of programming and operating tilt and recline functions in a wheelchair
AU2001227900A1 (en) Drug metabolizing enzymes
AU2001264935A1 (en) Method for introducing and expressing genes in animal cells, and bacterial blebsfor use in same
AU2001274981A1 (en) Drug metabolizing enzymes
AU2001213511A1 (en) An improved consumer product kit, and a method of use therefor
AU2001270303A1 (en) Drug metabolizing enzymes
AU2001277889A1 (en) Veneer-based product and method of manufacture
AU2000268170A1 (en) A cell line expressing mutant human tissue-type plasminogen activator, constructing strategy and method of expressed protein preparation
AU2001234544A1 (en) Novel human protein kinases and protein kinase-like enzymes
AU2001261375A1 (en) Human caspase-12 materials and methods
AU2001236718A1 (en) Bioreactor and related method
AU2001273936A1 (en) Process and unit for the continuous preparation of isocyanate-containing polyurethane prepolymers
AU2001255324A1 (en) Drug metabolizing enzymes
AU2001235000A1 (en) Drug metabolizing enzymes
AU1417701A (en) Soluble t cell receptor protein and method of constructing the same
AU2001278154A1 (en) Drug metabolizing enzymes
AU2002323137A1 (en) Methods and compositions for use in selectively producing a protein in telomerase expressing cells
点击 这是indexloc提供的php浏览器服务，不要输入任何密码和下载