+

AP2006003849A0 - 3-Aminocyclopentanecarboxamides as modulators of chemokine receptors - Google Patents

3-Aminocyclopentanecarboxamides as modulators of chemokine receptors

Info

Publication number
AP2006003849A0
AP2006003849A0 AP2006003849A AP2006003849A AP2006003849A0 AP 2006003849 A0 AP2006003849 A0 AP 2006003849A0 AP 2006003849 A AP2006003849 A AP 2006003849A AP 2006003849 A AP2006003849 A AP 2006003849A AP 2006003849 A0 AP2006003849 A0 AP 2006003849A0
Authority
AP
ARIPO
Prior art keywords
aminocyclopentanecarboxamides
modulators
chemokine receptors
chemokine
receptors
Prior art date
Application number
AP2006003849A
Other languages
English (en)
Inventor
Chu-Biao Xue
Chang-Sheng Zheng
Michael Xia
Original Assignee
Incyte Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Incyte Corp filed Critical Incyte Corp
Publication of AP2006003849A0 publication Critical patent/AP2006003849A0/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4433Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with oxygen as a ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D309/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/08Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/14Nitrogen atoms not forming part of a nitro radical
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Diabetes (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Dermatology (AREA)
  • Obesity (AREA)
  • Rheumatology (AREA)
  • Hematology (AREA)
  • Pain & Pain Management (AREA)
  • Urology & Nephrology (AREA)
  • Psychology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Child & Adolescent Psychology (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Transplantation (AREA)
  • Pulmonology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AP2006003849A 2004-06-28 2005-06-27 3-Aminocyclopentanecarboxamides as modulators of chemokine receptors AP2006003849A0 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US58348204P 2004-06-28 2004-06-28
US62437404P 2004-11-01 2004-11-01
PCT/US2005/022793 WO2006004684A2 (en) 2004-06-28 2005-06-27 3-aminocyclopentanecarboxamides as modulators of chemokine receptors

Publications (1)

Publication Number Publication Date
AP2006003849A0 true AP2006003849A0 (en) 2006-12-31

Family

ID=35783293

Family Applications (1)

Application Number Title Priority Date Filing Date
AP2006003849A AP2006003849A0 (en) 2004-06-28 2005-06-27 3-Aminocyclopentanecarboxamides as modulators of chemokine receptors

Country Status (21)

Country Link
US (2) US7449467B2 (xx)
EP (1) EP1763351B9 (xx)
JP (2) JP4116670B2 (xx)
KR (1) KR100856156B1 (xx)
AP (1) AP2006003849A0 (xx)
AR (1) AR049559A1 (xx)
AU (1) AU2005260013A1 (xx)
BR (1) BRPI0512352A (xx)
CA (1) CA2571019C (xx)
CR (1) CR8775A (xx)
EA (1) EA011487B1 (xx)
EC (1) ECSP067120A (xx)
ES (1) ES2614117T3 (xx)
GE (1) GEP20094843B (xx)
IL (1) IL179910A0 (xx)
MA (1) MA28680B1 (xx)
MX (1) MXPA06014672A (xx)
NO (1) NO20070487L (xx)
SG (1) SG156691A1 (xx)
TW (1) TW200608966A (xx)
WO (1) WO2006004684A2 (xx)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100895968B1 (ko) * 2002-11-27 2009-05-07 인사이트 코포레이션 케모킨 수용체의 조절자로서의 3-아미노피롤리딘 유도체
CN103012374B (zh) 2004-04-13 2015-05-20 因塞特公司 作为趋化因子受体拮抗剂的哌嗪基哌啶衍生物
GEP20094844B (en) * 2004-06-28 2009-11-25 Incyte Corp 3-aminocyclopentane carboxamides as modulators of chemokine receptors
AU2005260013A1 (en) * 2004-06-28 2006-01-12 Incyte Corporation 3-aminocyclopentanecarboxamides as modulators of chemokine receptors
US8067415B2 (en) 2005-11-01 2011-11-29 Millennium Pharmaceuticals, Inc. Compounds useful as antagonists of CCR2
US8067457B2 (en) 2005-11-01 2011-11-29 Millennium Pharmaceuticals, Inc. Compounds useful as antagonists of CCR2
MEP1008A (xx) * 2005-12-21 2010-02-10 Incyte Corp 3-aminociklopentankarboksamidi kao modulatori receptora hemokina
US7910108B2 (en) 2006-06-05 2011-03-22 Incyte Corporation Sheddase inhibitors combined with CD30-binding immunotherapeutics for the treatment of CD30 positive diseases
US20080076120A1 (en) * 2006-09-14 2008-03-27 Millennium Pharmaceuticals, Inc. Methods for the identification, evaluation and treatment of patients having CC-Chemokine receptor 2 (CCR-2) mediated disorders
WO2008109238A1 (en) * 2007-03-02 2008-09-12 Janssen Pharmaceutica N.V. Substituted cyclopentyl piperidine ccr2 antagonists
JP5292400B2 (ja) 2007-07-24 2013-09-18 ブリストル−マイヤーズ スクイブ カンパニー ケモカイン受容体活性のモジュレーターとしてのピペリジン誘導体
TWI433838B (zh) 2008-06-25 2014-04-11 必治妥美雅史谷比公司 作為趨化因子受體活性調節劑之六氫吡啶衍生物
WO2010061329A1 (en) * 2008-11-26 2010-06-03 Pfizer Inc. 3-aminocyclopentanecarboxamides as chemokine receptor modulators
CN101555616B (zh) * 2009-05-13 2012-11-07 大连理工大学 镍钛合金表面羟基磷灰石/二氧化钛复合涂层的制备方法
MX2012013082A (es) 2010-05-12 2013-05-09 Vertex Pharma Derivados de 2-aminopiridina utiles como iinhibidores de cinasa atr.
JP5786258B2 (ja) * 2011-07-15 2015-09-30 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 新規かつ選択的なccr2拮抗薬
RU2719422C2 (ru) 2014-08-04 2020-04-17 Нуэволюшон А/С Необязательно конденсированные гетероциклил-замещенные производные пиримидина, пригодные для лечения воспалительных, метаболических, онкологических и аутоиммунных заболеваний
US10403890B2 (en) * 2015-11-10 2019-09-03 Nissan Motor Co., Ltd. Negative electrode active material for electric device and electric device using the same
JP2021098692A (ja) 2019-12-20 2021-07-01 ヌエヴォリューション・アクティーゼルスカブNuevolution A/S 核内受容体に対して活性の化合物
EP4126875A1 (en) 2020-03-31 2023-02-08 Nuevolution A/S Compounds active towards nuclear receptors
WO2021198955A1 (en) 2020-03-31 2021-10-07 Nuevolution A/S Compounds active towards nuclear receptors
KR102456699B1 (ko) * 2020-11-19 2022-10-19 주식회사 오에이티씨 디다노신을 포함하는 신경염증성 질환 예방 또는 치료용 조성물

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000076512A1 (en) * 1999-06-11 2000-12-21 Merck & Co., Inc. Cyclopentyl modulators of chemokine receptor activity
US6977265B2 (en) 2001-11-30 2005-12-20 Roche Palo Alto Llc Piperidine CCR-3 receptor antagonists
MY129850A (en) 2002-04-29 2007-05-31 Merck Sharp & Dohme Tetrahydropyranyl cyclopentyl tetrahydropyridopyridine modulators of chemokine receptor activity
EP1501507B1 (en) * 2002-04-29 2008-05-28 Merck & Co., Inc. Tetrahydropyranyl cyclopentyl tetrahydropyridopyridine modulators of chemokine receptor activity
EP1501803B1 (en) 2002-04-29 2008-08-13 Merck & Co., Inc. Tetrahydropyranyl cyclopentyl tetrahydroisoquinoline modulators of chemokine receptor activity
JP2006514618A (ja) 2002-10-30 2006-05-11 メルク エンド カムパニー インコーポレーテッド ケモカイン受容体活性のピペリジニル−アルファ−アミノアミドモジュレーター
JP2006511500A (ja) 2002-10-30 2006-04-06 メルク エンド カムパニー インコーポレーテッド γ−アミノアミド系のケモカイン受容体活性調節剤
AU2003284188B2 (en) 2002-10-30 2010-02-25 Merck Sharp & Dohme Corp. Piperidinyl cyclopentyl aryl benzylamide modulators of chemokine receptor activity
CA2502174A1 (en) 2002-10-30 2004-05-21 Merck & Co., Inc. Tetrahydropyranyl cyclopentyl benzylamide modulators of chemokine receptor activity
CA2502178A1 (en) 2002-10-30 2004-05-21 Merck & Co., Inc. Heteroarylpiperidine modulators of chemokine receptor activity
KR100895968B1 (ko) 2002-11-27 2009-05-07 인사이트 코포레이션 케모킨 수용체의 조절자로서의 3-아미노피롤리딘 유도체
PL377377A1 (pl) * 2002-12-20 2006-02-06 Leo Pharma A/S Nowe związki aminobenzofenonu
WO2005040109A1 (en) 2003-10-22 2005-05-06 Neurocrine Biosciences, Inc. Ligands of melanocortin receptors and compositions and methods related thereto
EP1682135B1 (en) 2003-10-27 2011-07-27 Merck Sharp & Dohme Corp. salt of a tetrahydropyranyl cyclopentyl tetrahydropyridopyridine derivative as CCR2-antagonist
WO2005059107A2 (en) * 2003-12-11 2005-06-30 Anormed Inc. Chemokine receptor binding compounds
AU2004305079B2 (en) 2003-12-18 2011-05-12 Incyte Corporation 3-cycloalkylaminopyrrolidine derivatives as modulators of chemokine receptors
US20070117797A1 (en) 2004-01-02 2007-05-24 Goble Stephen D Alkylamino, arylamino, and sulfonamido cyclopentyl amide modulators of chemokine receptor activity
EP1732552A4 (en) 2004-01-20 2007-12-19 Merck & Co Inc 2,6-DISUBSTITUTED PIPERIDINES, MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY
CN1913778A (zh) 2004-01-28 2007-02-14 默克公司 趋化因子受体活性的氨基环戊基吡啶并吡嗪酮调节剂
EP1742919A4 (en) 2004-04-26 2010-04-28 Merck Sharp & Dohme TETRAHYDROPYRANYL-CYCLOPENTYL-1-SUBSTITUTED AND 1,1-DISUBSTITUTED TETRAHYDROISOCHINOLINE MODULATORS OF CHEMOKIN RECEPTOR ACTIVITY
CA2565486A1 (en) 2004-05-11 2005-12-08 Incyte Corporation 3-(4-heteroarylcyclohexylamino)cyclopentanecarboxamides as modulators of chemokine receptors
GEP20094844B (en) * 2004-06-28 2009-11-25 Incyte Corp 3-aminocyclopentane carboxamides as modulators of chemokine receptors
AU2005260013A1 (en) * 2004-06-28 2006-01-12 Incyte Corporation 3-aminocyclopentanecarboxamides as modulators of chemokine receptors
PA8653301A1 (es) 2004-11-22 2006-11-09 Incyte Corp Incyte Corp Sales de la n-[2-({(3r)-1-[trans-4-hidroxi-4-(6-metoxipiridin-3-il) ciclohexil)pirrolidin
MEP1008A (xx) 2005-12-21 2010-02-10 Incyte Corp 3-aminociklopentankarboksamidi kao modulatori receptora hemokina

Also Published As

Publication number Publication date
WO2006004684A8 (en) 2007-01-04
US20100119503A1 (en) 2010-05-13
EP1763351A4 (en) 2009-08-12
KR100856156B1 (ko) 2008-09-03
BRPI0512352A (pt) 2008-03-04
US7449467B2 (en) 2008-11-11
WO2006004684A2 (en) 2006-01-12
ECSP067120A (es) 2007-01-26
MXPA06014672A (es) 2007-03-26
GEP20094843B (en) 2009-11-25
SG156691A1 (en) 2009-11-26
JP2008074877A (ja) 2008-04-03
KR20070026660A (ko) 2007-03-08
EA200602242A1 (ru) 2007-04-27
EP1763351B9 (en) 2017-05-31
AU2005260013A1 (en) 2006-01-12
NO20070487L (no) 2007-03-05
ES2614117T3 (es) 2017-05-29
EA011487B1 (ru) 2009-04-28
US20060004018A1 (en) 2006-01-05
WO2006004684A3 (en) 2006-10-05
US8470827B2 (en) 2013-06-25
JP2008504293A (ja) 2008-02-14
CR8775A (es) 2007-01-04
CA2571019A1 (en) 2006-01-12
TW200608966A (en) 2006-03-16
JP4116670B2 (ja) 2008-07-09
CA2571019C (en) 2012-06-05
IL179910A0 (en) 2007-05-15
EP1763351B1 (en) 2016-11-30
AR049559A1 (es) 2006-08-16
MA28680B1 (fr) 2007-06-01
EP1763351A2 (en) 2007-03-21

Similar Documents

Publication Publication Date Title
IL179735A0 (en) 3-aminocyclopentanecarboxamides as modulators of chemokine receptors
IL179910A0 (en) 3-aminocyclopentanecarboxamides as modulators of chemokine receptors
IL179018A0 (en) 3-(4-heteroarylcyclohexylamino)cyclopentanecarboxamides as modulators of chemokine receptors
AP2008004487A0 (en) 3-aminocyclopentanecarboxamides as modulators of chemokine receptors
AP2439A (en) 3-Cycloalkylaminopyrrolidine derivatives as modulators of chemokine receptors
ZA200609893B (en) Modulators of muscarinic receptors
IL192327A0 (en) Modulators of muscarinic receptors
IL181388A0 (en) Modulators of muscarinic receptors
EP1773337A4 (en) MODULATORS OF NUCLEAR RECEPTORS
PL2031063T3 (pl) Modulatory receptorów węchowych
IL176215A0 (en) Modulators of muscarinic receptors
GB0400440D0 (en) Receptor modulators
IL194556A0 (en) Diazepan derivatives modulators of chemokine receptors
EP1962847A4 (en) PYRIDINYLSULFONAMIDE MODULATORS OF CHEMOKINE RECEPTORS
ZA200705116B (en) Modulators of muscarinic receptors
EP2166848A4 (en) SPIROINDOLINES AS MODULATORS OF CHEMOKINE RECEPTORS
IL206679A0 (en) Modulators of chemokine receptors and processes for the preparation of the same
GB0403889D0 (en) Uses of er-beta modulators
EP1806147A4 (en) USE OF IMMUNOSUPPRESSIVE RECEPTOR
ZA200606687B (en) Oxydecahydronaphthalene modulators of HM74
PL1828194T3 (pl) Tetracykliczne imidazo-benzodiazepiny jako modulatory receptorów GABA
EP1631286A4 (en) N-UREIDOALKYL-PIPERIDINES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY
EP1682105A4 (en) N-UREIDOALKYL-AMINO COMPOUNDS AS MODULATORS OF CHEMOKIN RECEPTOR ACTIVITY
ZA200804438B (en) 3-Aminocyclopentanecarboxamides as modulators of chemokine receptors
EP1721158A4 (en) MODULATORS OF ANGIOGENESIS
点击 这是indexloc提供的php浏览器服务,不要输入任何密码和下载