AP2006003849A0 - 3-Aminocyclopentanecarboxamides as modulators of chemokine receptors - Google Patents

3-Aminocyclopentanecarboxamides as modulators of chemokine receptors

Info

Publication number: AP2006003849A0
Authority: AP; ARIPO
Prior art keywords: aminocyclopentanecarboxamides; modulators; chemokine receptors; chemokine; receptors
Prior art date: 2004-06-28

Application number

AP2006003849A

Other languages

English (en)

Inventor

Chu-Biao Xue

Chang-Sheng Zheng

Michael Xia

Original Assignee

Incyte Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2004-06-28

Filing date

2005-06-27

Publication date

2006-12-31

2005-06-27 Application filed by Incyte Corp filed Critical Incyte Corp

2006-12-31 Publication of AP2006003849A0 publication Critical patent/AP2006003849A0/xx

Links

OLHSXPNNEJJDLQ-UHFFFAOYSA-N 3-aminocyclopentane-1-carboxamide Chemical class NC1CCC(C(N)=O)C1 OLHSXPNNEJJDLQ-UHFFFAOYSA-N 0.000 title 1
102000009410 Chemokine receptor Human genes 0.000 title 1
108050000299 Chemokine receptor Proteins 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4433—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with oxygen as a ring hetero atom
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D309/14—Nitrogen atoms not forming part of a nitro radical
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Immunology (AREA)
Diabetes (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Rheumatology (AREA)
Dermatology (AREA)
Hematology (AREA)
Obesity (AREA)
Cardiology (AREA)
Pulmonology (AREA)
Heart & Thoracic Surgery (AREA)
Vascular Medicine (AREA)
Urology & Nephrology (AREA)
Child & Adolescent Psychology (AREA)
Psychology (AREA)
Pain & Pain Management (AREA)
Endocrinology (AREA)
Transplantation (AREA)
Orthopedic Medicine & Surgery (AREA)
Physical Education & Sports Medicine (AREA)
Emergency Medicine (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

AP2006003849A 2004-06-28 2005-06-27 3-Aminocyclopentanecarboxamides as modulators of chemokine receptors AP2006003849A0 (en)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US58348204P	2004-06-28	2004-06-28
US62437404P	2004-11-01	2004-11-01
PCT/US2005/022793 WO2006004684A2 (en)	2004-06-28	2005-06-27	3-aminocyclopentanecarboxamides as modulators of chemokine receptors

Publications (1)

Publication Number	Publication Date
AP2006003849A0 true AP2006003849A0 (en)	2006-12-31

Family

ID=35783293

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AP2006003849A AP2006003849A0 (en)	2004-06-28	2005-06-27	3-Aminocyclopentanecarboxamides as modulators of chemokine receptors

Country Status (21)

Country	Link
US (2)	US7449467B2 (xx)
EP (1)	EP1763351B9 (xx)
JP (2)	JP4116670B2 (xx)
KR (1)	KR100856156B1 (xx)
AP (1)	AP2006003849A0 (xx)
AR (1)	AR049559A1 (xx)
AU (1)	AU2005260013A1 (xx)
BR (1)	BRPI0512352A (xx)
CA (1)	CA2571019C (xx)
CR (1)	CR8775A (xx)
EA (1)	EA011487B1 (xx)
EC (1)	ECSP067120A (xx)
ES (1)	ES2614117T3 (xx)
GE (1)	GEP20094843B (xx)
IL (1)	IL179910A0 (xx)
MA (1)	MA28680B1 (xx)
MX (1)	MXPA06014672A (xx)
NO (1)	NO20070487L (xx)
SG (1)	SG156691A1 (xx)
TW (1)	TW200608966A (xx)
WO (1)	WO2006004684A2 (xx)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
BRPI0316732B8 (pt) *	2002-11-27	2021-05-25	Incyte Corp	composto derivado de 3-aminopirrolidina e sua composição farmacêutica
CA2562235C (en)	2004-04-13	2013-09-24	Incyte Corporation	Piperazinylpiperidine derivatives as chemokine receptor antagonists
AU2005259983B2 (en) *	2004-06-28	2011-07-28	Incyte Corporation	3-aminocyclopentanecarboxamides as modulators of chemokine receptors
KR100856156B1 (ko) *	2004-06-28	2008-09-03	인사이트 코포레이션	케모카인 수용체의 조절자로서의3-아미노사이클로펜탄카복스아마이드
WO2007053499A2 (en)	2005-11-01	2007-05-10	Millennium Pharmaceuticals, Inc.	Compounds useful as antagonists of ccr2
US8067457B2 (en)	2005-11-01	2011-11-29	Millennium Pharmaceuticals, Inc.	Compounds useful as antagonists of CCR2
MEP1008A (xx) *	2005-12-21	2010-02-10	Incyte Corp	3-aminociklopentankarboksamidi kao modulatori receptora hemokina
US7910108B2 (en)	2006-06-05	2011-03-22	Incyte Corporation	Sheddase inhibitors combined with CD30-binding immunotherapeutics for the treatment of CD30 positive diseases
US20080076120A1 (en) *	2006-09-14	2008-03-27	Millennium Pharmaceuticals, Inc.	Methods for the identification, evaluation and treatment of patients having CC-Chemokine receptor 2 (CCR-2) mediated disorders
WO2008109238A1 (en) *	2007-03-02	2008-09-12	Janssen Pharmaceutica N.V.	Substituted cyclopentyl piperidine ccr2 antagonists
US8536198B2 (en) *	2007-07-24	2013-09-17	Bristol-Myers Squibb Company	Piperidine derivatives as modulators of chemokine receptor activity
TWI433838B (zh)	2008-06-25	2014-04-11	必治妥美雅史谷比公司	作為趨化因子受體活性調節劑之六氫吡啶衍生物
RS52810B8 (sr) *	2008-11-26	2019-08-30	Pfizer	3-aminociklopentankarboksamidi kao modulatori hemokinskih receptora
CN101555616B (zh) *	2009-05-13	2012-11-07	大连理工大学	镍钛合金表面羟基磷灰石/二氧化钛复合涂层的制备方法
AU2011253021A1 (en)	2010-05-12	2012-11-29	Vertex Pharmaceuticals Incorporated	2 -aminopyridine derivatives useful as inhibitors of ATR kinase
JP5786258B2 (ja) *	2011-07-15	2015-09-30	ベーリンガーインゲルハイムインターナショナルゲゼルシャフトミットベシュレンクテルハフツング	新規かつ選択的なｃｃｒ２拮抗薬
JP6604664B2 (ja)	2014-08-04	2019-11-13	ヌエヴォリューション・アクティーゼルスカブ	核内受容体に対して活性な化合物
CN108352513B (zh) *	2015-11-10	2019-10-01	日产自动车株式会社	电气设备用负极活性物质和使用了其的电气设备
WO2021124277A1 (en)	2019-12-20	2021-06-24	Nuevolution A/S	Compounds active towards nuclear receptors
MX2022012260A (es)	2020-03-31	2022-11-30	Nuevolution As	Compuestos activos frente a receptores nucleares.
AU2021249530A1 (en)	2020-03-31	2022-12-01	Nuevolution A/S	Compounds active towards nuclear receptors
WO2022108381A1 (ko)	2020-11-19	2022-05-27	주식회사 오에이티씨	디다노신을 포함하는 신경염증성 질환 예방 또는 치료용 조성물

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6500844B1 (en) *	1999-06-11	2002-12-31	Merck & Co., Inc.	Cyclopentyl modulators of chemokine receptor activity
US6977265B2 (en)	2001-11-30	2005-12-20	Roche Palo Alto Llc	Piperidine CCR-3 receptor antagonists
WO2003093231A2 (en)	2002-04-29	2003-11-13	Merck & Co., Inc.	Tetrahydropyranyl cyclopentyl tetrahydroisoquinoline modulators of chemokine receptor activity
MY129850A (en) *	2002-04-29	2007-05-31	Merck Sharp & Dohme	Tetrahydropyranyl cyclopentyl tetrahydropyridopyridine modulators of chemokine receptor activity
ATE396993T1 (de) *	2002-04-29	2008-06-15	Merck & Co Inc	Tetrahydropyranyl-cyclopentyl- tetrahydropyridopyridin-modulatoren der chemokin- rezeptor-aktivität
JP2006514003A (ja)	2002-10-30	2006-04-27	メルク　エンド　カムパニー　インコーポレーテッド	ケモカイン受容体活性のテトラヒドロピラニルシクロペンチルベンジルアミド調節剤
US20050250814A1 (en)	2002-10-30	2005-11-10	Cangyou Zhou	Piperidinyl-alpha-aminoamide modulators of chemokine receptor activity
AU2003284984B2 (en)	2002-10-30	2008-10-23	Merck Sharp & Dohme Corp.	Gamma-aminoamide modulators of chemokine receptor activity
JP2006507301A (ja)	2002-10-30	2006-03-02	メルク　エンド　カムパニー　インコーポレーテッド	ケモカイン受容体活性のピペリジニルシクロペンチルアリールベンジルアミドモジュレーター
WO2004041777A2 (en)	2002-10-30	2004-05-21	Merck & Co., Inc.	Heteroarylpiperidine modulators of chemokine receptor activity
BRPI0316732B8 (pt) *	2002-11-27	2021-05-25	Incyte Corp	composto derivado de 3-aminopirrolidina e sua composição farmacêutica
KR20050089056A (ko) *	2002-12-20	2005-09-07	레오 파마 에이/에스	신규한 아미노벤조페논 화합물
US20050192286A1 (en) *	2003-10-22	2005-09-01	Neurocrine Biosciences, Inc.	Ligands of melanocortin receptors and compositions and methods related thereto
KR20060101476A (ko)	2003-10-27	2006-09-25	머크 앤드 캄파니 인코포레이티드	Ｃｃｒ-2 길항제 염
CA2548393A1 (en) *	2003-12-11	2005-06-30	Anormed Inc.	Chemokine receptor binding compounds
OA13338A (en)	2003-12-18	2007-04-13	Incyte Corp	3-cycloalkylaminopyrrolidine derivates as modulators of chemokine receptors.
JP2007519633A (ja)	2004-01-02	2007-07-19	メルク　エンド　カムパニー　インコーポレーテッド	アルキルアミノ、アリールアミノおよびスルホンアミドシクロペンチルアミド系のケモカイン受容体活性調節剤
US7410961B2 (en)	2004-01-20	2008-08-12	Merck & Co., Inc.	2,6-disubstituted piperiddines as modulators
US20070155731A1 (en)	2004-01-28	2007-07-05	Gabor Butora	Aminocyclopentyl pyridopyrazinone modulators of chemokine receptor activity
JP2007534758A (ja)	2004-04-26	2007-11-29	メルク　エンド　カムパニー　インコーポレーテッド	ケモカイン受容体活性調節物質であるテトラヒドロピラニルシクロペンチル１−置換及び１，１−二置換テトラヒドロイソキノリン
WO2005115392A2 (en) *	2004-05-11	2005-12-08	Incyte Corporation	3-(4-heteroarylcyclohexylamino) cyclopentanecarboxamides as modulators of chemokine receptors
AU2005259983B2 (en) *	2004-06-28	2011-07-28	Incyte Corporation	3-aminocyclopentanecarboxamides as modulators of chemokine receptors
KR100856156B1 (ko) *	2004-06-28	2008-09-03	인사이트 코포레이션	케모카인 수용체의 조절자로서의3-아미노사이클로펜탄카복스아마이드
UY29219A1 (es) *	2004-11-22	2006-04-28	Incyte Corp	Sales de la n-(2- (((3r)-1-(trans-4-hidroxi-4-(6-metoxipiridin-3-il)-cilohexil) pirrolidin-3-il)amino)-2-oxoetil)-3- (trifluorometil) benzamida
MEP1008A (xx) *	2005-12-21	2010-02-10	Incyte Corp	3-aminociklopentankarboksamidi kao modulatori receptora hemokina

2005
- 2005-06-27 KR KR1020067027464A patent/KR100856156B1/ko not_active Expired - Fee Related
- 2005-06-27 GE GEAP20059758A patent/GEP20094843B/en unknown
- 2005-06-27 SG SG200907284-4A patent/SG156691A1/en unknown
- 2005-06-27 CA CA2571019A patent/CA2571019C/en not_active Expired - Fee Related
- 2005-06-27 US US11/167,816 patent/US7449467B2/en active Active
- 2005-06-27 WO PCT/US2005/022793 patent/WO2006004684A2/en active Application Filing
- 2005-06-27 JP JP2007518357A patent/JP4116670B2/ja not_active Expired - Fee Related
- 2005-06-27 AP AP2006003849A patent/AP2006003849A0/xx unknown
- 2005-06-27 BR BRPI0512352-6A patent/BRPI0512352A/pt not_active IP Right Cessation
- 2005-06-27 AU AU2005260013A patent/AU2005260013A1/en not_active Abandoned
- 2005-06-27 ES ES05790938.4T patent/ES2614117T3/es active Active
- 2005-06-27 EA EA200602242A patent/EA011487B1/ru not_active IP Right Cessation
- 2005-06-27 MX MXPA06014672A patent/MXPA06014672A/es unknown
- 2005-06-27 EP EP05790938.4A patent/EP1763351B9/en active Active
- 2005-06-27 TW TW094121454A patent/TW200608966A/zh unknown
- 2005-06-28 AR ARP050102676A patent/AR049559A1/es unknown
2006
- 2006-11-28 CR CR8775A patent/CR8775A/es not_active Application Discontinuation
- 2006-12-07 IL IL179910A patent/IL179910A0/en unknown
- 2006-12-27 EC EC2006007120A patent/ECSP067120A/es unknown
- 2006-12-28 MA MA29560A patent/MA28680B1/fr unknown
2007
- 2007-01-25 NO NO20070487A patent/NO20070487L/no not_active Application Discontinuation
- 2007-12-12 JP JP2007321252A patent/JP2008074877A/ja active Pending
2008
- 2008-09-25 US US12/238,121 patent/US8470827B2/en active Active

Also Published As

Publication number	Publication date
KR20070026660A (ko)	2007-03-08
MXPA06014672A (es)	2007-03-26
CR8775A (es)	2007-01-04
CA2571019C (en)	2012-06-05
US20060004018A1 (en)	2006-01-05
SG156691A1 (en)	2009-11-26
KR100856156B1 (ko)	2008-09-03
MA28680B1 (fr)	2007-06-01
IL179910A0 (en)	2007-05-15
EP1763351A2 (en)	2007-03-21
JP2008504293A (ja)	2008-02-14
AR049559A1 (es)	2006-08-16
EP1763351B1 (en)	2016-11-30
ES2614117T3 (es)	2017-05-29
ECSP067120A (es)	2007-01-26
EP1763351A4 (en)	2009-08-12
US8470827B2 (en)	2013-06-25
TW200608966A (en)	2006-03-16
US20100119503A1 (en)	2010-05-13
GEP20094843B (en)	2009-11-25
JP4116670B2 (ja)	2008-07-09
CA2571019A1 (en)	2006-01-12
NO20070487L (no)	2007-03-05
EA200602242A1 (ru)	2007-04-27
WO2006004684A8 (en)	2007-01-04
EP1763351B9 (en)	2017-05-31
WO2006004684A2 (en)	2006-01-12
EA011487B1 (ru)	2009-04-28
AU2005260013A1 (en)	2006-01-12
WO2006004684A3 (en)	2006-10-05
US7449467B2 (en)	2008-11-11
BRPI0512352A (pt)	2008-03-04
JP2008074877A (ja)	2008-04-03

Publication	Publication Date	Title
IL179735A0 (en)	2007-05-15	3-aminocyclopentanecarboxamides as modulators of chemokine receptors
IL179910A0 (en)	2007-05-15	3-aminocyclopentanecarboxamides as modulators of chemokine receptors
IL179018A0 (en)	2007-03-08	3-(4-heteroarylcyclohexylamino)cyclopentanecarboxamides as modulators of chemokine receptors
IL191602A0 (en)	2009-02-11	3-aminocyclopentanecarboxamides as modulators of chemokine receptors
AP2439A (en)	2012-08-31	3-Cycloalkylaminopyrrolidine derivatives as modulators of chemokine receptors
ZA200609893B (en)	2008-08-27	Modulators of muscarinic receptors
ZA200806028B (en)	2009-04-29	Modulators of muscarinic receptors
ZA200701397B (en)	2009-04-29	Modulators of muscarinic receptors
EP1773337A4 (en)	2009-11-11	MODULATORS OF NUCLEAR RECEPTORS
PL2031063T3 (pl)	2014-04-30	Modulatory receptorów węchowych
IL176215A0 (en)	2006-10-05	Modulators of muscarinic receptors
GB0400440D0 (en)	2004-02-11	Receptor modulators
IL194556A0 (en)	2009-08-03	Diazepan derivatives modulators of chemokine receptors
EP1962847A4 (en)	2010-10-06	PYRIDINYLSULFONAMIDE MODULATORS OF CHEMOKINE RECEPTORS
ZA200705116B (en)	2008-06-25	Modulators of muscarinic receptors
EP2166848A4 (en)	2011-08-03	SPIROINDOLINES AS MODULATORS OF CHEMOKINE RECEPTORS
IL206679A0 (en)	2010-12-30	Modulators of chemokine receptors and processes for the preparation of the same
GB0403889D0 (en)	2004-03-24	Uses of er-beta modulators
EP1806147A4 (en)	2009-07-01	USE OF IMMUNOSUPPRESSIVE RECEPTOR
ZA200606687B (en)	2008-02-27	Oxydecahydronaphthalene modulators of HM74
PL1828194T3 (pl)	2008-11-28	Tetracykliczne imidazo-benzodiazepiny jako modulatory receptorów GABA
EP1631286A4 (en)	2007-08-29	N-UREIDOALKYL-PIPERIDINES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY
EP1682105A4 (en)	2008-12-24	N-UREIDOALKYL-AMINO COMPOUNDS AS MODULATORS OF CHEMOKIN RECEPTOR ACTIVITY
ZA200804438B (en)	2009-09-30	3-Aminocyclopentanecarboxamides as modulators of chemokine receptors
EP1721158A4 (en)	2008-07-30	MODULATORS OF ANGIOGENESIS