AP2006003849A0 - 3-Aminocyclopentanecarboxamides as modulators of chemokine receptors - Google Patents

3-Aminocyclopentanecarboxamides as modulators of chemokine receptors

Info

Publication number: AP2006003849A0
Authority: AP; ARIPO
Prior art keywords: aminocyclopentanecarboxamides; modulators; chemokine receptors; chemokine; receptors
Prior art date: 2004-06-28

Application number

AP2006003849A

Other languages

English (en)

Inventor

Chu-Biao Xue

Chang-Sheng Zheng

Michael Xia

Original Assignee

Incyte Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2004-06-28

Filing date

2005-06-27

Publication date

2006-12-31

2005-06-27 Application filed by Incyte Corp filed Critical Incyte Corp

2006-12-31 Publication of AP2006003849A0 publication Critical patent/AP2006003849A0/xx

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4433—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with oxygen as a ring hetero atom
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D309/14—Nitrogen atoms not forming part of a nitro radical
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Immunology (AREA)
Diabetes (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Dermatology (AREA)
Obesity (AREA)
Rheumatology (AREA)
Hematology (AREA)
Pain & Pain Management (AREA)
Urology & Nephrology (AREA)
Psychology (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Vascular Medicine (AREA)
Child & Adolescent Psychology (AREA)
Emergency Medicine (AREA)
Endocrinology (AREA)
Transplantation (AREA)
Pulmonology (AREA)
Orthopedic Medicine & Surgery (AREA)
Physical Education & Sports Medicine (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

AP2006003849A 2004-06-28 2005-06-27 3-Aminocyclopentanecarboxamides as modulators of chemokine receptors AP2006003849A0 (en)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US58348204P	2004-06-28	2004-06-28
US62437404P	2004-11-01	2004-11-01
PCT/US2005/022793 WO2006004684A2 (en)	2004-06-28	2005-06-27	3-aminocyclopentanecarboxamides as modulators of chemokine receptors

Publications (1)

Publication Number	Publication Date
AP2006003849A0 true AP2006003849A0 (en)	2006-12-31

Family

ID=35783293

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AP2006003849A AP2006003849A0 (en)	2004-06-28	2005-06-27	3-Aminocyclopentanecarboxamides as modulators of chemokine receptors

Country Status (21)

Country	Link
US (2)	US7449467B2 (xx)
EP (1)	EP1763351B9 (xx)
JP (2)	JP4116670B2 (xx)
KR (1)	KR100856156B1 (xx)
AP (1)	AP2006003849A0 (xx)
AR (1)	AR049559A1 (xx)
AU (1)	AU2005260013A1 (xx)
BR (1)	BRPI0512352A (xx)
CA (1)	CA2571019C (xx)
CR (1)	CR8775A (xx)
EA (1)	EA011487B1 (xx)
EC (1)	ECSP067120A (xx)
ES (1)	ES2614117T3 (xx)
GE (1)	GEP20094843B (xx)
IL (1)	IL179910A0 (xx)
MA (1)	MA28680B1 (xx)
MX (1)	MXPA06014672A (xx)
NO (1)	NO20070487L (xx)
SG (1)	SG156691A1 (xx)
TW (1)	TW200608966A (xx)
WO (1)	WO2006004684A2 (xx)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
KR100895968B1 (ko) *	2002-11-27	2009-05-07	인사이트 코포레이션	케모킨 수용체의 조절자로서의 3-아미노피롤리딘 유도체
CN103012374B (zh)	2004-04-13	2015-05-20	因塞特公司	作为趋化因子受体拮抗剂的哌嗪基哌啶衍生物
GEP20094844B (en) *	2004-06-28	2009-11-25	Incyte Corp	3-aminocyclopentane carboxamides as modulators of chemokine receptors
AU2005260013A1 (en) *	2004-06-28	2006-01-12	Incyte Corporation	3-aminocyclopentanecarboxamides as modulators of chemokine receptors
US8067415B2 (en)	2005-11-01	2011-11-29	Millennium Pharmaceuticals, Inc.	Compounds useful as antagonists of CCR2
US8067457B2 (en)	2005-11-01	2011-11-29	Millennium Pharmaceuticals, Inc.	Compounds useful as antagonists of CCR2
MEP1008A (xx) *	2005-12-21	2010-02-10	Incyte Corp	3-aminociklopentankarboksamidi kao modulatori receptora hemokina
US7910108B2 (en)	2006-06-05	2011-03-22	Incyte Corporation	Sheddase inhibitors combined with CD30-binding immunotherapeutics for the treatment of CD30 positive diseases
US20080076120A1 (en) *	2006-09-14	2008-03-27	Millennium Pharmaceuticals, Inc.	Methods for the identification, evaluation and treatment of patients having CC-Chemokine receptor 2 (CCR-2) mediated disorders
WO2008109238A1 (en) *	2007-03-02	2008-09-12	Janssen Pharmaceutica N.V.	Substituted cyclopentyl piperidine ccr2 antagonists
JP5292400B2 (ja)	2007-07-24	2013-09-18	ブリストル−マイヤーズスクイブカンパニー	ケモカイン受容体活性のモジュレーターとしてのピペリジン誘導体
TWI433838B (zh)	2008-06-25	2014-04-11	必治妥美雅史谷比公司	作為趨化因子受體活性調節劑之六氫吡啶衍生物
WO2010061329A1 (en) *	2008-11-26	2010-06-03	Pfizer Inc.	3-aminocyclopentanecarboxamides as chemokine receptor modulators
CN101555616B (zh) *	2009-05-13	2012-11-07	大连理工大学	镍钛合金表面羟基磷灰石/二氧化钛复合涂层的制备方法
MX2012013082A (es)	2010-05-12	2013-05-09	Vertex Pharma	Derivados de 2-aminopiridina utiles como iinhibidores de cinasa atr.
JP5786258B2 (ja) *	2011-07-15	2015-09-30	ベーリンガーインゲルハイムインターナショナルゲゼルシャフトミットベシュレンクテルハフツング	新規かつ選択的なｃｃｒ２拮抗薬
RU2719422C2 (ru)	2014-08-04	2020-04-17	Нуэволюшон А/С	Необязательно конденсированные гетероциклил-замещенные производные пиримидина, пригодные для лечения воспалительных, метаболических, онкологических и аутоиммунных заболеваний
US10403890B2 (en) *	2015-11-10	2019-09-03	Nissan Motor Co., Ltd.	Negative electrode active material for electric device and electric device using the same
JP2021098692A (ja)	2019-12-20	2021-07-01	ヌエヴォリューション・アクティーゼルスカブＮｕｅｖｏｌｕｔｉｏｎＡ／Ｓ	核内受容体に対して活性の化合物
EP4126875A1 (en)	2020-03-31	2023-02-08	Nuevolution A/S	Compounds active towards nuclear receptors
WO2021198955A1 (en)	2020-03-31	2021-10-07	Nuevolution A/S	Compounds active towards nuclear receptors
KR102456699B1 (ko) *	2020-11-19	2022-10-19	주식회사 오에이티씨	디다노신을 포함하는 신경염증성 질환 예방 또는 치료용 조성물

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2000076512A1 (en) *	1999-06-11	2000-12-21	Merck & Co., Inc.	Cyclopentyl modulators of chemokine receptor activity
US6977265B2 (en)	2001-11-30	2005-12-20	Roche Palo Alto Llc	Piperidine CCR-3 receptor antagonists
MY129850A (en)	2002-04-29	2007-05-31	Merck Sharp & Dohme	Tetrahydropyranyl cyclopentyl tetrahydropyridopyridine modulators of chemokine receptor activity
EP1501507B1 (en) *	2002-04-29	2008-05-28	Merck & Co., Inc.	Tetrahydropyranyl cyclopentyl tetrahydropyridopyridine modulators of chemokine receptor activity
EP1501803B1 (en)	2002-04-29	2008-08-13	Merck & Co., Inc.	Tetrahydropyranyl cyclopentyl tetrahydroisoquinoline modulators of chemokine receptor activity
JP2006514618A (ja)	2002-10-30	2006-05-11	メルク　エンド　カムパニー　インコーポレーテッド	ケモカイン受容体活性のピペリジニル−アルファ−アミノアミドモジュレーター
JP2006511500A (ja)	2002-10-30	2006-04-06	メルク　エンド　カムパニー　インコーポレーテッド	γ−アミノアミド系のケモカイン受容体活性調節剤
AU2003284188B2 (en)	2002-10-30	2010-02-25	Merck Sharp & Dohme Corp.	Piperidinyl cyclopentyl aryl benzylamide modulators of chemokine receptor activity
CA2502174A1 (en)	2002-10-30	2004-05-21	Merck & Co., Inc.	Tetrahydropyranyl cyclopentyl benzylamide modulators of chemokine receptor activity
CA2502178A1 (en)	2002-10-30	2004-05-21	Merck & Co., Inc.	Heteroarylpiperidine modulators of chemokine receptor activity
KR100895968B1 (ko)	2002-11-27	2009-05-07	인사이트 코포레이션	케모킨 수용체의 조절자로서의 3-아미노피롤리딘 유도체
PL377377A1 (pl) *	2002-12-20	2006-02-06	Leo Pharma A/S	Nowe związki aminobenzofenonu
WO2005040109A1 (en)	2003-10-22	2005-05-06	Neurocrine Biosciences, Inc.	Ligands of melanocortin receptors and compositions and methods related thereto
EP1682135B1 (en)	2003-10-27	2011-07-27	Merck Sharp & Dohme Corp.	salt of a tetrahydropyranyl cyclopentyl tetrahydropyridopyridine derivative as CCR2-antagonist
WO2005059107A2 (en) *	2003-12-11	2005-06-30	Anormed Inc.	Chemokine receptor binding compounds
AU2004305079B2 (en)	2003-12-18	2011-05-12	Incyte Corporation	3-cycloalkylaminopyrrolidine derivatives as modulators of chemokine receptors
US20070117797A1 (en)	2004-01-02	2007-05-24	Goble Stephen D	Alkylamino, arylamino, and sulfonamido cyclopentyl amide modulators of chemokine receptor activity
EP1732552A4 (en)	2004-01-20	2007-12-19	Merck & Co Inc	2,6-DISUBSTITUTED PIPERIDINES, MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY
CN1913778A (zh)	2004-01-28	2007-02-14	默克公司	趋化因子受体活性的氨基环戊基吡啶并吡嗪酮调节剂
EP1742919A4 (en)	2004-04-26	2010-04-28	Merck Sharp & Dohme	TETRAHYDROPYRANYL-CYCLOPENTYL-1-SUBSTITUTED AND 1,1-DISUBSTITUTED TETRAHYDROISOCHINOLINE MODULATORS OF CHEMOKIN RECEPTOR ACTIVITY
CA2565486A1 (en)	2004-05-11	2005-12-08	Incyte Corporation	3-(4-heteroarylcyclohexylamino)cyclopentanecarboxamides as modulators of chemokine receptors
GEP20094844B (en) *	2004-06-28	2009-11-25	Incyte Corp	3-aminocyclopentane carboxamides as modulators of chemokine receptors
AU2005260013A1 (en) *	2004-06-28	2006-01-12	Incyte Corporation	3-aminocyclopentanecarboxamides as modulators of chemokine receptors
PA8653301A1 (es)	2004-11-22	2006-11-09	Incyte Corp Incyte Corp	Sales de la n-[2-({(3r)-1-[trans-4-hidroxi-4-(6-metoxipiridin-3-il) ciclohexil)pirrolidin
MEP1008A (xx)	2005-12-21	2010-02-10	Incyte Corp	3-aminociklopentankarboksamidi kao modulatori receptora hemokina

2005
- 2005-06-27 AU AU2005260013A patent/AU2005260013A1/en not_active Abandoned
- 2005-06-27 MX MXPA06014672A patent/MXPA06014672A/es unknown
- 2005-06-27 GE GEAP20059758A patent/GEP20094843B/en unknown
- 2005-06-27 US US11/167,816 patent/US7449467B2/en active Active
- 2005-06-27 BR BRPI0512352-6A patent/BRPI0512352A/pt not_active IP Right Cessation
- 2005-06-27 CA CA2571019A patent/CA2571019C/en not_active Expired - Fee Related
- 2005-06-27 AP AP2006003849A patent/AP2006003849A0/xx unknown
- 2005-06-27 WO PCT/US2005/022793 patent/WO2006004684A2/en active Application Filing
- 2005-06-27 TW TW094121454A patent/TW200608966A/zh unknown
- 2005-06-27 KR KR1020067027464A patent/KR100856156B1/ko not_active Expired - Fee Related
- 2005-06-27 SG SG200907284-4A patent/SG156691A1/en unknown
- 2005-06-27 JP JP2007518357A patent/JP4116670B2/ja not_active Expired - Fee Related
- 2005-06-27 EA EA200602242A patent/EA011487B1/ru not_active IP Right Cessation
- 2005-06-27 ES ES05790938.4T patent/ES2614117T3/es active Active
- 2005-06-27 EP EP05790938.4A patent/EP1763351B9/en active Active
- 2005-06-28 AR ARP050102676A patent/AR049559A1/es unknown
2006
- 2006-11-28 CR CR8775A patent/CR8775A/es not_active Application Discontinuation
- 2006-12-07 IL IL179910A patent/IL179910A0/en unknown
- 2006-12-27 EC EC2006007120A patent/ECSP067120A/es unknown
- 2006-12-28 MA MA29560A patent/MA28680B1/fr unknown
2007
- 2007-01-25 NO NO20070487A patent/NO20070487L/no not_active Application Discontinuation
- 2007-12-12 JP JP2007321252A patent/JP2008074877A/ja active Pending
2008
- 2008-09-25 US US12/238,121 patent/US8470827B2/en active Active

Also Published As

Publication number	Publication date
WO2006004684A8 (en)	2007-01-04
US20100119503A1 (en)	2010-05-13
EP1763351A4 (en)	2009-08-12
KR100856156B1 (ko)	2008-09-03
BRPI0512352A (pt)	2008-03-04
US7449467B2 (en)	2008-11-11
WO2006004684A2 (en)	2006-01-12
ECSP067120A (es)	2007-01-26
MXPA06014672A (es)	2007-03-26
GEP20094843B (en)	2009-11-25
SG156691A1 (en)	2009-11-26
JP2008074877A (ja)	2008-04-03
KR20070026660A (ko)	2007-03-08
EA200602242A1 (ru)	2007-04-27
EP1763351B9 (en)	2017-05-31
AU2005260013A1 (en)	2006-01-12
NO20070487L (no)	2007-03-05
ES2614117T3 (es)	2017-05-29
EA011487B1 (ru)	2009-04-28
US20060004018A1 (en)	2006-01-05
WO2006004684A3 (en)	2006-10-05
US8470827B2 (en)	2013-06-25
JP2008504293A (ja)	2008-02-14
CR8775A (es)	2007-01-04
CA2571019A1 (en)	2006-01-12
TW200608966A (en)	2006-03-16
JP4116670B2 (ja)	2008-07-09
CA2571019C (en)	2012-06-05
IL179910A0 (en)	2007-05-15
EP1763351B1 (en)	2016-11-30
AR049559A1 (es)	2006-08-16
MA28680B1 (fr)	2007-06-01
EP1763351A2 (en)	2007-03-21

Publication	Publication Date	Title
IL179735A0 (en)	2007-05-15	3-aminocyclopentanecarboxamides as modulators of chemokine receptors
IL179910A0 (en)	2007-05-15	3-aminocyclopentanecarboxamides as modulators of chemokine receptors
IL179018A0 (en)	2007-03-08	3-(4-heteroarylcyclohexylamino)cyclopentanecarboxamides as modulators of chemokine receptors
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