NO20081934L - Diaryleterderivater som antitumor midler - Google Patents
Diaryleterderivater som antitumor midlerInfo
- Publication number
- NO20081934L NO20081934L NO20081934A NO20081934A NO20081934L NO 20081934 L NO20081934 L NO 20081934L NO 20081934 A NO20081934 A NO 20081934A NO 20081934 A NO20081934 A NO 20081934A NO 20081934 L NO20081934 L NO 20081934L
- Authority
- NO
- Norway
- Prior art keywords
- group
- formula
- antitumor agents
- ether derivatives
- hydrogen atom
- Prior art date
Links
- 239000002246 antineoplastic agent Substances 0.000 title 1
- 150000001987 diarylethers Chemical class 0.000 title 1
- 239000003814 drug Substances 0.000 abstract 2
- 229940079593 drug Drugs 0.000 abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 2
- 239000004480 active ingredient Substances 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000002947 alkylene group Chemical group 0.000 abstract 1
- 230000000259 anti-tumor effect Effects 0.000 abstract 1
- 125000002619 bicyclic group Chemical group 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- 125000002883 imidazolyl group Chemical group 0.000 abstract 1
- 125000002950 monocyclic group Chemical group 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 125000004430 oxygen atom Chemical group O* 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 229920006395 saturated elastomer Polymers 0.000 abstract 1
- 125000004434 sulfur atom Chemical group 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2005351255 | 2005-12-05 | ||
PCT/JP2006/324610 WO2007066784A2 (fr) | 2005-12-05 | 2006-12-04 | Substance medicamenteuse |
Publications (1)
Publication Number | Publication Date |
---|---|
NO20081934L true NO20081934L (no) | 2008-08-13 |
Family
ID=38051953
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20081934A NO20081934L (no) | 2005-12-05 | 2008-04-23 | Diaryleterderivater som antitumor midler |
Country Status (22)
Country | Link |
---|---|
US (1) | US8236826B2 (fr) |
EP (1) | EP1957073B1 (fr) |
KR (1) | KR101157004B1 (fr) |
CN (1) | CN101321529B (fr) |
AR (1) | AR056885A1 (fr) |
AU (1) | AU2006323700B2 (fr) |
BR (1) | BRPI0619349A2 (fr) |
CA (1) | CA2630468C (fr) |
CY (1) | CY1115171T1 (fr) |
DK (1) | DK1957073T3 (fr) |
ES (1) | ES2463450T3 (fr) |
HK (1) | HK1123219A1 (fr) |
IL (1) | IL191544A0 (fr) |
MY (1) | MY146514A (fr) |
NO (1) | NO20081934L (fr) |
PL (1) | PL1957073T3 (fr) |
PT (1) | PT1957073E (fr) |
RU (1) | RU2444362C2 (fr) |
SI (1) | SI1957073T1 (fr) |
TW (1) | TWI332838B (fr) |
WO (1) | WO2007066784A2 (fr) |
ZA (1) | ZA200804445B (fr) |
Families Citing this family (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2573223C (fr) | 2004-08-06 | 2013-05-21 | Otsuka Pharmaceutical Co., Ltd. | Compose aromatique |
UA95978C2 (ru) * | 2006-10-02 | 2011-09-26 | Оцука Фармас'Ютікел Ко., Лтд. | Ингибитор активации stat3/5 |
CN101597278B (zh) | 2008-06-04 | 2013-04-17 | 中国中化股份有限公司 | 酰胺类化合物及其制备与应用 |
KR20110088575A (ko) | 2008-11-21 | 2011-08-03 | 하이 포인트 파마슈티칼스, 엘엘씨 | 아다만틸 벤즈아미드 화합물 |
CN102459185B (zh) | 2009-04-20 | 2015-06-03 | 田边三菱制药株式会社 | 新型甲状腺激素β受体激动剂 |
WO2011047156A1 (fr) | 2009-10-15 | 2011-04-21 | Hercules Technology Management Co V, Inc. | Inhibiteurs de sépiaptérine réductase pour le traitement de la douleur |
KR101411030B1 (ko) | 2010-01-29 | 2014-06-30 | 오쓰까 세이야꾸 가부시키가이샤 | 항암제로서의 2 - 치환 피리딘 유도체 |
WO2012015715A1 (fr) | 2010-07-27 | 2012-02-02 | High Point Pharmaceuticals, Llc | Dérivés de thiazol-2-ylamine substitués, compositions pharmaceutiques et procédés d'utilisation en tant que modulateurs de 11-bêta-hsd1 |
EP2624833B1 (fr) | 2010-10-04 | 2014-12-10 | Otsuka Pharmaceutical Co., Ltd. | Dérivés de 4-(méthylaminophénoxy)pyridin-3-yl-benzamide pour le traitement du cancer |
WO2012090177A2 (fr) * | 2010-12-30 | 2012-07-05 | Lupin Limited | Modulateurs des récepteurs cannabinoïdes |
IN2014MN00226A (fr) * | 2011-07-05 | 2015-09-25 | Lupin Ltd | |
TW201329025A (zh) | 2011-11-01 | 2013-07-16 | Astex Therapeutics Ltd | 醫藥化合物 |
US9376376B2 (en) | 2012-03-14 | 2016-06-28 | Sinochem Corporation | Substitute diphenylamine compounds use thereof as antitumor agents |
JP6066806B2 (ja) * | 2012-04-03 | 2017-01-25 | 大塚製薬株式会社 | 医薬 |
SG11201506514QA (en) | 2013-02-19 | 2015-09-29 | Ono Pharmaceutical Co | Trk-INHIBITING COMPOUND |
CA2919397C (fr) * | 2013-09-09 | 2021-05-18 | Peloton Therapeutics, Inc. | Ethers aryliques comme inhibiteurs h1f-2-alpha pour le traitement du cancer |
CN106536518B (zh) * | 2014-05-19 | 2020-05-12 | 勃林格殷格翰动物保健美国公司 | 驱蠕虫化合物 |
TW201617314A (zh) * | 2014-09-10 | 2016-05-16 | 第一三共股份有限公司 | 羧酸衍生物 |
CN107098884A (zh) * | 2016-02-19 | 2017-08-29 | 中国科学院上海药物研究所 | 一类取代的氨基吡啶类化合物及其制备和用途 |
JP7444458B2 (ja) * | 2018-09-21 | 2024-03-06 | 学校法人福岡大学 | プリオン病治療薬 |
AU2023224057A1 (en) * | 2022-02-28 | 2024-08-15 | Sironax Ltd. | Rip1 modulators, preparations, and uses thereof |
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BE629102A (fr) * | 1961-03-29 | |||
NL7111711A (fr) | 1970-09-17 | 1972-03-21 | ||
US3715375A (en) * | 1970-09-17 | 1973-02-06 | Merck & Co Inc | New diphenyl sulfones |
GB1494117A (en) | 1974-11-02 | 1977-12-07 | Bayer Ag | Process for the preparation of acid amides |
DE2707659A1 (de) * | 1977-02-23 | 1978-08-24 | Bayer Ag | Selbstvernetzbare polyurethane |
DE2707660C2 (de) * | 1977-02-23 | 1985-12-19 | Bayer Ag, 5090 Leverkusen | Abspalter- und Diolrest enthaltende Diisocyanat-Addukte, ihre Herstellung und Verwendung |
DE2812252A1 (de) * | 1978-03-21 | 1979-10-04 | Bayer Ag | 1,2,4-triazol-blockierte polyisocyanate als vernetzer fuer lackbindemittel |
US4978672A (en) * | 1986-03-07 | 1990-12-18 | Ciba-Geigy Corporation | Alpha-heterocyclc substituted tolunitriles |
EP0500495A3 (en) * | 1991-02-21 | 1993-04-07 | Ciba-Geigy Ag | Thermosetting composition |
EP0580550B1 (fr) | 1992-07-21 | 1997-10-22 | Novartis AG | Dérivés de l'acide oxamique utilisés comme agents hypocholestérémiques |
WO1995001326A1 (fr) | 1993-06-30 | 1995-01-12 | The Wellcome Foundation Limited | Composes de diaryle contre l'atherosclerose |
JPH11511121A (ja) | 1995-06-07 | 1999-09-28 | インスティテュート オブ マテリア メディカ | カルコンレチノイドおよびその使用方法 |
US6022884A (en) * | 1997-11-07 | 2000-02-08 | Amgen Inc. | Substituted pyridine compounds and methods of use |
AU2723099A (en) | 1998-02-06 | 1999-08-23 | Byk Gulden Lomberg Chemische Fabrik Gmbh | Tryptase inhibitors |
EP1060175B1 (fr) | 1998-02-06 | 2004-11-17 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. | Inhibiteurs de la tryptase |
AR015733A1 (es) * | 1998-03-25 | 2001-05-16 | Otsuka Pharma Co Ltd | DERIVADO DE PIRIDINA, EL PRODUCTO Y LA COMPOSICIoN FARMACEUTICA QUE CONTIENE DICHO DERIVADO. |
TWI245035B (en) | 1998-06-26 | 2005-12-11 | Ono Pharmaceutical Co | Amino acid derivatives and a pharmaceutical composition comprising the derivatives |
EP1101755B1 (fr) * | 1998-07-24 | 2004-10-06 | Teijin Limited | Derives d'acide anthranilique |
US20020065296A1 (en) * | 1999-01-13 | 2002-05-30 | Bayer Corporation | Heteroaryl ureas containing nitrogen hetero-atoms as p38 kinase inhibitors |
WO2000042012A1 (fr) | 1999-01-13 | 2000-07-20 | Bayer Corporation | DIPHENYLUREES A SUBSTITUANTS φ-CARBOXYARYLES, INHIBITRICES DE KINASE RAF |
AU2871900A (en) | 1999-02-04 | 2000-08-25 | Millennium Pharmaceuticals, Inc. | G-protein coupled heptahelical receptor binding compounds and methods of use thereof |
CO5160290A1 (es) | 1999-03-29 | 2002-05-30 | Novartis Ag | Derivados de acido fenoxifeniloxamico sustituido . |
US6159694A (en) * | 1999-04-08 | 2000-12-12 | Isis Pharmaceuticals Inc. | Antisense modulation of stat3 expression |
WO2001002359A1 (fr) | 1999-07-01 | 2001-01-11 | Ajinomoto Co., Inc. | Composes heterocycliques et leurs applications en medecine |
JP2001089450A (ja) | 1999-09-22 | 2001-04-03 | Otsuka Pharmaceut Co Ltd | ピリジン誘導体含有医薬製剤 |
JP2001089412A (ja) | 1999-09-22 | 2001-04-03 | Otsuka Pharmaceut Co Ltd | ベンゼン誘導体またはその医薬的に許容される塩 |
US20030220402A1 (en) * | 2000-02-15 | 2003-11-27 | Naoki Tsuchiya | Cancer remedy comprising anthranilic acid derivatives as active ingredients |
PL360495A1 (en) | 2000-05-22 | 2004-09-06 | Aventis Pharmaceuticals Inc. | Arylmethylamine derivatives for use as tryptase inhibitors |
GB0015205D0 (en) | 2000-06-21 | 2000-08-09 | Karobio Ab | Bioisosteric thyroid receptor ligands and method |
JP2004506735A (ja) | 2000-08-18 | 2004-03-04 | ファルマシア・アンド・アップジョン・カンパニー | 疾患治療用キヌクリジン置換アリール化合物 |
AU2001295850A1 (en) | 2000-09-28 | 2002-04-08 | Nanocyte Inc. | Methods, compositions and devices utilizing stinging cells/capsules for delivering a therapeutic or a cosmetic agent into a tissue |
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EP1211235A3 (fr) | 2000-11-30 | 2004-01-02 | JFE Chemical Corporation | Procédé de préparation d'éthers d'acide diphényldicarboxylique et ses dérivés |
JP2004269356A (ja) | 2000-12-27 | 2004-09-30 | Ajinomoto Co Inc | 創傷部癒着防止剤 |
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WO2003018586A1 (fr) | 2001-08-24 | 2003-03-06 | Pharmacia & Upjohn Company | Aryl 7-aza[2.2.1]bicycloheptanes substitues utiles dans le traitement de maladies |
IL160974A0 (en) | 2001-10-22 | 2004-08-31 | Pfizer Prod Inc | Piperazine derivatives with ccr1 receptor antagonist activity |
WO2003035602A1 (fr) | 2001-10-25 | 2003-05-01 | Sankyo Company, Limited | Modulateurs lipidiques |
JP2005522456A (ja) | 2002-02-15 | 2005-07-28 | ファルマシア・アンド・アップジョン・カンパニー・エルエルシー | Cns関連障害治療のためのアザビシクロ置換ベンゾイルアミドおよびチオアミド |
FR2836917B1 (fr) | 2002-03-11 | 2006-02-24 | Lipha | Derives nitroso de la diphenylamine, compositions pharmaceutiques les contenant en tant que medicaments utilisables dans le traitement des pathologies caracterisees par une situation de stress oxydatif |
JP2004035475A (ja) | 2002-07-03 | 2004-02-05 | Ajinomoto Co Inc | TGFβ作用抑制剤 |
JP4736043B2 (ja) | 2003-03-14 | 2011-07-27 | 小野薬品工業株式会社 | 含窒素複素環誘導体およびそれらを有効成分とする薬剤 |
EP1651595A2 (fr) | 2003-05-30 | 2006-05-03 | Rigel Pharmaceuticals, Inc. | Inhibiteurs de ligase d'ubiquitine |
BRPI0412893A (pt) * | 2003-07-24 | 2006-10-03 | Leo Pharma As | composto, composição farmacêutica, uso de um composto, e, métodos de prevenção, tratamento ou melhora de doenças ou condições inflamatórias, ou doenças ou condições oftálmicas, de tratamento ou melhora de cáncer e para a produção de um composto |
CA2573223C (fr) * | 2004-08-06 | 2013-05-21 | Otsuka Pharmaceutical Co., Ltd. | Compose aromatique |
UA95978C2 (ru) * | 2006-10-02 | 2011-09-26 | Оцука Фармас'Ютікел Ко., Лтд. | Ингибитор активации stat3/5 |
TWI440638B (zh) * | 2007-10-30 | 2014-06-11 | Otsuka Pharma Co Ltd | 雜環化合物及其藥學組成物 |
-
2006
- 2006-12-04 RU RU2008127325/15A patent/RU2444362C2/ru not_active IP Right Cessation
- 2006-12-04 ZA ZA200804445A patent/ZA200804445B/xx unknown
- 2006-12-04 PL PL06834365T patent/PL1957073T3/pl unknown
- 2006-12-04 EP EP06834365.6A patent/EP1957073B1/fr not_active Not-in-force
- 2006-12-04 MY MYPI20081824A patent/MY146514A/en unknown
- 2006-12-04 BR BRPI0619349-8A patent/BRPI0619349A2/pt not_active IP Right Cessation
- 2006-12-04 CN CN2006800454525A patent/CN101321529B/zh not_active Expired - Fee Related
- 2006-12-04 US US12/095,930 patent/US8236826B2/en not_active Expired - Fee Related
- 2006-12-04 AU AU2006323700A patent/AU2006323700B2/en not_active Ceased
- 2006-12-04 DK DK06834365.6T patent/DK1957073T3/da active
- 2006-12-04 KR KR1020087013451A patent/KR101157004B1/ko not_active Expired - Fee Related
- 2006-12-04 CA CA2630468A patent/CA2630468C/fr not_active Expired - Fee Related
- 2006-12-04 WO PCT/JP2006/324610 patent/WO2007066784A2/fr active Application Filing
- 2006-12-04 PT PT68343656T patent/PT1957073E/pt unknown
- 2006-12-04 SI SI200631802T patent/SI1957073T1/sl unknown
- 2006-12-04 ES ES06834365.6T patent/ES2463450T3/es active Active
- 2006-12-05 AR ARP060105371A patent/AR056885A1/es unknown
- 2006-12-05 TW TW095145184A patent/TWI332838B/zh active
-
2008
- 2008-04-23 NO NO20081934A patent/NO20081934L/no not_active Application Discontinuation
- 2008-05-19 IL IL191544A patent/IL191544A0/en not_active IP Right Cessation
-
2009
- 2009-03-31 HK HK09103076.2A patent/HK1123219A1/xx not_active IP Right Cessation
-
2014
- 2014-05-05 CY CY20141100316T patent/CY1115171T1/el unknown
Also Published As
Publication number | Publication date |
---|---|
HK1123219A1 (en) | 2009-06-12 |
EP1957073A2 (fr) | 2008-08-20 |
IL191544A0 (en) | 2008-12-29 |
TW200800200A (en) | 2008-01-01 |
WO2007066784A2 (fr) | 2007-06-14 |
US20100004438A1 (en) | 2010-01-07 |
DK1957073T3 (da) | 2014-05-12 |
AU2006323700A1 (en) | 2007-06-14 |
ES2463450T3 (es) | 2014-05-28 |
RU2008127325A (ru) | 2010-01-20 |
CA2630468A1 (fr) | 2007-06-14 |
CN101321529B (zh) | 2012-09-05 |
ZA200804445B (en) | 2009-11-25 |
AR056885A1 (es) | 2007-10-31 |
TWI332838B (en) | 2010-11-11 |
CY1115171T1 (el) | 2016-12-14 |
PT1957073E (pt) | 2014-05-12 |
SI1957073T1 (sl) | 2014-08-29 |
EP1957073B1 (fr) | 2014-04-23 |
AU2006323700B2 (en) | 2011-02-17 |
BRPI0619349A2 (pt) | 2011-11-08 |
KR101157004B1 (ko) | 2012-07-09 |
US8236826B2 (en) | 2012-08-07 |
RU2444362C2 (ru) | 2012-03-10 |
WO2007066784A3 (fr) | 2007-10-25 |
PL1957073T3 (pl) | 2014-09-30 |
CA2630468C (fr) | 2015-01-20 |
KR20080070054A (ko) | 2008-07-29 |
CN101321529A (zh) | 2008-12-10 |
MY146514A (en) | 2012-08-15 |
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Legal Events
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FC2A | Withdrawal, rejection or dismissal of laid open patent application |