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NO20081934L - Diaryleterderivater som antitumor midler - Google Patents

Diaryleterderivater som antitumor midler

Info

Publication number
NO20081934L
NO20081934L NO20081934A NO20081934A NO20081934L NO 20081934 L NO20081934 L NO 20081934L NO 20081934 A NO20081934 A NO 20081934A NO 20081934 A NO20081934 A NO 20081934A NO 20081934 L NO20081934 L NO 20081934L
Authority
NO
Norway
Prior art keywords
group
formula
antitumor agents
ether derivatives
hydrogen atom
Prior art date
Application number
NO20081934A
Other languages
English (en)
Norwegian (no)
Inventor
Takashi Nakagawa
Hironori Matsuyama
Kenji Ohnishi
Hideki Takasu
Makoto Sakamoto
Kumi Higuchi
Keisuke Miyajima
Satoshi Yamada
Masaaki Motoyama
Yutaka Kojima
Koichi Yasumura
Takeshi Kodama
Shun Otsuji
Keizo Kan
Takumi Sumida
Original Assignee
Otsuka Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Otsuka Pharma Co Ltd filed Critical Otsuka Pharma Co Ltd
Publication of NO20081934L publication Critical patent/NO20081934L/no

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
NO20081934A 2005-12-05 2008-04-23 Diaryleterderivater som antitumor midler NO20081934L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2005351255 2005-12-05
PCT/JP2006/324610 WO2007066784A2 (fr) 2005-12-05 2006-12-04 Substance medicamenteuse

Publications (1)

Publication Number Publication Date
NO20081934L true NO20081934L (no) 2008-08-13

Family

ID=38051953

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20081934A NO20081934L (no) 2005-12-05 2008-04-23 Diaryleterderivater som antitumor midler

Country Status (22)

Country Link
US (1) US8236826B2 (fr)
EP (1) EP1957073B1 (fr)
KR (1) KR101157004B1 (fr)
CN (1) CN101321529B (fr)
AR (1) AR056885A1 (fr)
AU (1) AU2006323700B2 (fr)
BR (1) BRPI0619349A2 (fr)
CA (1) CA2630468C (fr)
CY (1) CY1115171T1 (fr)
DK (1) DK1957073T3 (fr)
ES (1) ES2463450T3 (fr)
HK (1) HK1123219A1 (fr)
IL (1) IL191544A0 (fr)
MY (1) MY146514A (fr)
NO (1) NO20081934L (fr)
PL (1) PL1957073T3 (fr)
PT (1) PT1957073E (fr)
RU (1) RU2444362C2 (fr)
SI (1) SI1957073T1 (fr)
TW (1) TWI332838B (fr)
WO (1) WO2007066784A2 (fr)
ZA (1) ZA200804445B (fr)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2573223C (fr) 2004-08-06 2013-05-21 Otsuka Pharmaceutical Co., Ltd. Compose aromatique
UA95978C2 (ru) * 2006-10-02 2011-09-26 Оцука Фармас'Ютікел Ко., Лтд. Ингибитор активации stat3/5
CN101597278B (zh) 2008-06-04 2013-04-17 中国中化股份有限公司 酰胺类化合物及其制备与应用
KR20110088575A (ko) 2008-11-21 2011-08-03 하이 포인트 파마슈티칼스, 엘엘씨 아다만틸 벤즈아미드 화합물
CN102459185B (zh) 2009-04-20 2015-06-03 田边三菱制药株式会社 新型甲状腺激素β受体激动剂
WO2011047156A1 (fr) 2009-10-15 2011-04-21 Hercules Technology Management Co V, Inc. Inhibiteurs de sépiaptérine réductase pour le traitement de la douleur
KR101411030B1 (ko) 2010-01-29 2014-06-30 오쓰까 세이야꾸 가부시키가이샤 항암제로서의 2 - 치환 피리딘 유도체
WO2012015715A1 (fr) 2010-07-27 2012-02-02 High Point Pharmaceuticals, Llc Dérivés de thiazol-2-ylamine substitués, compositions pharmaceutiques et procédés d'utilisation en tant que modulateurs de 11-bêta-hsd1
EP2624833B1 (fr) 2010-10-04 2014-12-10 Otsuka Pharmaceutical Co., Ltd. Dérivés de 4-(méthylaminophénoxy)pyridin-3-yl-benzamide pour le traitement du cancer
WO2012090177A2 (fr) * 2010-12-30 2012-07-05 Lupin Limited Modulateurs des récepteurs cannabinoïdes
IN2014MN00226A (fr) * 2011-07-05 2015-09-25 Lupin Ltd
TW201329025A (zh) 2011-11-01 2013-07-16 Astex Therapeutics Ltd 醫藥化合物
US9376376B2 (en) 2012-03-14 2016-06-28 Sinochem Corporation Substitute diphenylamine compounds use thereof as antitumor agents
JP6066806B2 (ja) * 2012-04-03 2017-01-25 大塚製薬株式会社 医薬
SG11201506514QA (en) 2013-02-19 2015-09-29 Ono Pharmaceutical Co Trk-INHIBITING COMPOUND
CA2919397C (fr) * 2013-09-09 2021-05-18 Peloton Therapeutics, Inc. Ethers aryliques comme inhibiteurs h1f-2-alpha pour le traitement du cancer
CN106536518B (zh) * 2014-05-19 2020-05-12 勃林格殷格翰动物保健美国公司 驱蠕虫化合物
TW201617314A (zh) * 2014-09-10 2016-05-16 第一三共股份有限公司 羧酸衍生物
CN107098884A (zh) * 2016-02-19 2017-08-29 中国科学院上海药物研究所 一类取代的氨基吡啶类化合物及其制备和用途
JP7444458B2 (ja) * 2018-09-21 2024-03-06 学校法人福岡大学 プリオン病治療薬
AU2023224057A1 (en) * 2022-02-28 2024-08-15 Sironax Ltd. Rip1 modulators, preparations, and uses thereof

Family Cites Families (48)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE629102A (fr) * 1961-03-29
NL7111711A (fr) 1970-09-17 1972-03-21
US3715375A (en) * 1970-09-17 1973-02-06 Merck & Co Inc New diphenyl sulfones
GB1494117A (en) 1974-11-02 1977-12-07 Bayer Ag Process for the preparation of acid amides
DE2707659A1 (de) * 1977-02-23 1978-08-24 Bayer Ag Selbstvernetzbare polyurethane
DE2707660C2 (de) * 1977-02-23 1985-12-19 Bayer Ag, 5090 Leverkusen Abspalter- und Diolrest enthaltende Diisocyanat-Addukte, ihre Herstellung und Verwendung
DE2812252A1 (de) * 1978-03-21 1979-10-04 Bayer Ag 1,2,4-triazol-blockierte polyisocyanate als vernetzer fuer lackbindemittel
US4978672A (en) * 1986-03-07 1990-12-18 Ciba-Geigy Corporation Alpha-heterocyclc substituted tolunitriles
EP0500495A3 (en) * 1991-02-21 1993-04-07 Ciba-Geigy Ag Thermosetting composition
EP0580550B1 (fr) 1992-07-21 1997-10-22 Novartis AG Dérivés de l'acide oxamique utilisés comme agents hypocholestérémiques
WO1995001326A1 (fr) 1993-06-30 1995-01-12 The Wellcome Foundation Limited Composes de diaryle contre l'atherosclerose
JPH11511121A (ja) 1995-06-07 1999-09-28 インスティテュート オブ マテリア メディカ カルコンレチノイドおよびその使用方法
US6022884A (en) * 1997-11-07 2000-02-08 Amgen Inc. Substituted pyridine compounds and methods of use
AU2723099A (en) 1998-02-06 1999-08-23 Byk Gulden Lomberg Chemische Fabrik Gmbh Tryptase inhibitors
EP1060175B1 (fr) 1998-02-06 2004-11-17 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Inhibiteurs de la tryptase
AR015733A1 (es) * 1998-03-25 2001-05-16 Otsuka Pharma Co Ltd DERIVADO DE PIRIDINA, EL PRODUCTO Y LA COMPOSICIoN FARMACEUTICA QUE CONTIENE DICHO DERIVADO.
TWI245035B (en) 1998-06-26 2005-12-11 Ono Pharmaceutical Co Amino acid derivatives and a pharmaceutical composition comprising the derivatives
EP1101755B1 (fr) * 1998-07-24 2004-10-06 Teijin Limited Derives d'acide anthranilique
US20020065296A1 (en) * 1999-01-13 2002-05-30 Bayer Corporation Heteroaryl ureas containing nitrogen hetero-atoms as p38 kinase inhibitors
WO2000042012A1 (fr) 1999-01-13 2000-07-20 Bayer Corporation DIPHENYLUREES A SUBSTITUANTS φ-CARBOXYARYLES, INHIBITRICES DE KINASE RAF
AU2871900A (en) 1999-02-04 2000-08-25 Millennium Pharmaceuticals, Inc. G-protein coupled heptahelical receptor binding compounds and methods of use thereof
CO5160290A1 (es) 1999-03-29 2002-05-30 Novartis Ag Derivados de acido fenoxifeniloxamico sustituido .
US6159694A (en) * 1999-04-08 2000-12-12 Isis Pharmaceuticals Inc. Antisense modulation of stat3 expression
WO2001002359A1 (fr) 1999-07-01 2001-01-11 Ajinomoto Co., Inc. Composes heterocycliques et leurs applications en medecine
JP2001089450A (ja) 1999-09-22 2001-04-03 Otsuka Pharmaceut Co Ltd ピリジン誘導体含有医薬製剤
JP2001089412A (ja) 1999-09-22 2001-04-03 Otsuka Pharmaceut Co Ltd ベンゼン誘導体またはその医薬的に許容される塩
US20030220402A1 (en) * 2000-02-15 2003-11-27 Naoki Tsuchiya Cancer remedy comprising anthranilic acid derivatives as active ingredients
PL360495A1 (en) 2000-05-22 2004-09-06 Aventis Pharmaceuticals Inc. Arylmethylamine derivatives for use as tryptase inhibitors
GB0015205D0 (en) 2000-06-21 2000-08-09 Karobio Ab Bioisosteric thyroid receptor ligands and method
JP2004506735A (ja) 2000-08-18 2004-03-04 ファルマシア・アンド・アップジョン・カンパニー 疾患治療用キヌクリジン置換アリール化合物
AU2001295850A1 (en) 2000-09-28 2002-04-08 Nanocyte Inc. Methods, compositions and devices utilizing stinging cells/capsules for delivering a therapeutic or a cosmetic agent into a tissue
AU2002223626A1 (en) 2000-10-20 2002-04-29 Novartis Ag Combinations of a thyromimetic compound and a statin
EP1211235A3 (fr) 2000-11-30 2004-01-02 JFE Chemical Corporation Procédé de préparation d'éthers d'acide diphényldicarboxylique et ses dérivés
JP2004269356A (ja) 2000-12-27 2004-09-30 Ajinomoto Co Inc 創傷部癒着防止剤
GB2374009A (en) 2001-02-12 2002-10-09 Novartis Ag Method of treating hair loss
OA12623A (en) 2001-06-20 2006-06-12 Pfizer Prod Inc Novel sulfonic acid derivatives.
WO2003018586A1 (fr) 2001-08-24 2003-03-06 Pharmacia & Upjohn Company Aryl 7-aza[2.2.1]bicycloheptanes substitues utiles dans le traitement de maladies
IL160974A0 (en) 2001-10-22 2004-08-31 Pfizer Prod Inc Piperazine derivatives with ccr1 receptor antagonist activity
WO2003035602A1 (fr) 2001-10-25 2003-05-01 Sankyo Company, Limited Modulateurs lipidiques
JP2005522456A (ja) 2002-02-15 2005-07-28 ファルマシア・アンド・アップジョン・カンパニー・エルエルシー Cns関連障害治療のためのアザビシクロ置換ベンゾイルアミドおよびチオアミド
FR2836917B1 (fr) 2002-03-11 2006-02-24 Lipha Derives nitroso de la diphenylamine, compositions pharmaceutiques les contenant en tant que medicaments utilisables dans le traitement des pathologies caracterisees par une situation de stress oxydatif
JP2004035475A (ja) 2002-07-03 2004-02-05 Ajinomoto Co Inc TGFβ作用抑制剤
JP4736043B2 (ja) 2003-03-14 2011-07-27 小野薬品工業株式会社 含窒素複素環誘導体およびそれらを有効成分とする薬剤
EP1651595A2 (fr) 2003-05-30 2006-05-03 Rigel Pharmaceuticals, Inc. Inhibiteurs de ligase d'ubiquitine
BRPI0412893A (pt) * 2003-07-24 2006-10-03 Leo Pharma As composto, composição farmacêutica, uso de um composto, e, métodos de prevenção, tratamento ou melhora de doenças ou condições inflamatórias, ou doenças ou condições oftálmicas, de tratamento ou melhora de cáncer e para a produção de um composto
CA2573223C (fr) * 2004-08-06 2013-05-21 Otsuka Pharmaceutical Co., Ltd. Compose aromatique
UA95978C2 (ru) * 2006-10-02 2011-09-26 Оцука Фармас'Ютікел Ко., Лтд. Ингибитор активации stat3/5
TWI440638B (zh) * 2007-10-30 2014-06-11 Otsuka Pharma Co Ltd 雜環化合物及其藥學組成物

Also Published As

Publication number Publication date
HK1123219A1 (en) 2009-06-12
EP1957073A2 (fr) 2008-08-20
IL191544A0 (en) 2008-12-29
TW200800200A (en) 2008-01-01
WO2007066784A2 (fr) 2007-06-14
US20100004438A1 (en) 2010-01-07
DK1957073T3 (da) 2014-05-12
AU2006323700A1 (en) 2007-06-14
ES2463450T3 (es) 2014-05-28
RU2008127325A (ru) 2010-01-20
CA2630468A1 (fr) 2007-06-14
CN101321529B (zh) 2012-09-05
ZA200804445B (en) 2009-11-25
AR056885A1 (es) 2007-10-31
TWI332838B (en) 2010-11-11
CY1115171T1 (el) 2016-12-14
PT1957073E (pt) 2014-05-12
SI1957073T1 (sl) 2014-08-29
EP1957073B1 (fr) 2014-04-23
AU2006323700B2 (en) 2011-02-17
BRPI0619349A2 (pt) 2011-11-08
KR101157004B1 (ko) 2012-07-09
US8236826B2 (en) 2012-08-07
RU2444362C2 (ru) 2012-03-10
WO2007066784A3 (fr) 2007-10-25
PL1957073T3 (pl) 2014-09-30
CA2630468C (fr) 2015-01-20
KR20080070054A (ko) 2008-07-29
CN101321529A (zh) 2008-12-10
MY146514A (en) 2012-08-15

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