NO20080304L - Behandlingsmetoder ved bruk av hydrokinon-ansamyciner - Google Patents
Behandlingsmetoder ved bruk av hydrokinon-ansamycinerInfo
- Publication number
- NO20080304L NO20080304L NO20080304A NO20080304A NO20080304L NO 20080304 L NO20080304 L NO 20080304L NO 20080304 A NO20080304 A NO 20080304A NO 20080304 A NO20080304 A NO 20080304A NO 20080304 L NO20080304 L NO 20080304L
- Authority
- NO
- Norway
- Prior art keywords
- benzoquinone
- hydroquinone
- treatment
- methods
- ansamycins
- Prior art date
Links
- QIGBRXMKCJKVMJ-UHFFFAOYSA-N Hydroquinone Chemical compound OC1=CC=C(O)C=C1 QIGBRXMKCJKVMJ-UHFFFAOYSA-N 0.000 title abstract 5
- AZQWKYJCGOJGHM-UHFFFAOYSA-N 1,4-benzoquinone Chemical compound O=C1C=CC(=O)C=C1 AZQWKYJCGOJGHM-UHFFFAOYSA-N 0.000 abstract 3
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D225/00—Heterocyclic compounds containing rings of more than seven members having one nitrogen atom as the only ring hetero atom
- C07D225/04—Heterocyclic compounds containing rings of more than seven members having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D225/06—Heterocyclic compounds containing rings of more than seven members having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems condensed with one six-membered ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Hematology (AREA)
- Pulmonology (AREA)
- Diabetes (AREA)
- Child & Adolescent Psychology (AREA)
- Obesity (AREA)
- Oncology (AREA)
- Immunology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Saccharide Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Medicines Containing Plant Substances (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11/180,314 US20060019941A1 (en) | 2003-12-23 | 2005-07-13 | Analogs of benzoquinone-containing ansamycins and methods of use thereof |
| PCT/US2006/027113 WO2007009007A2 (fr) | 2005-07-13 | 2006-07-13 | Methodes de traitement utilisant des ansamycines d'hydroquinone |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO20080304L true NO20080304L (no) | 2008-02-29 |
Family
ID=37637939
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20080304A NO20080304L (no) | 2005-07-13 | 2008-01-16 | Behandlingsmetoder ved bruk av hydrokinon-ansamyciner |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US20060019941A1 (fr) |
| EP (1) | EP1904057B1 (fr) |
| JP (1) | JP2009501234A (fr) |
| KR (1) | KR20080030093A (fr) |
| CN (1) | CN101267816A (fr) |
| AT (1) | ATE451919T1 (fr) |
| AU (1) | AU2006268196A1 (fr) |
| BR (1) | BRPI0612870A2 (fr) |
| CA (1) | CA2612506A1 (fr) |
| DE (1) | DE602006011161D1 (fr) |
| ES (1) | ES2337397T3 (fr) |
| IL (1) | IL188355A0 (fr) |
| MX (1) | MX2007016469A (fr) |
| NO (1) | NO20080304L (fr) |
| WO (1) | WO2007009007A2 (fr) |
| ZA (1) | ZA200800906B (fr) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BRPI0418147A (pt) | 2003-12-23 | 2007-04-17 | Infinity Pharmaceuticals Inc | análogos de ansamicinas contendo benzoquinona e seus métodos de uso |
| US7608611B2 (en) * | 2005-03-11 | 2009-10-27 | The Regents Of The University Of Colorado | Hsp90 inhibitors, methods of making and uses therefor |
| EP1906950A4 (fr) * | 2005-06-21 | 2008-09-24 | Infinity Discovery Inc | Formulations d'ansamycine et leurs procedes d'utilisation |
| FR2907453B1 (fr) | 2006-10-24 | 2008-12-26 | Sanofi Aventis Sa | Nouveaux derives du fluorene,compositions les contenant et utilisation |
| PE20081506A1 (es) | 2006-12-12 | 2008-12-09 | Infinity Discovery Inc | Formulaciones de ansamicina |
| EP2134338A1 (fr) * | 2007-04-12 | 2009-12-23 | Infinity Discovery, Inc. | Formulations d'ansamycine hydroquinone |
| US8551964B2 (en) | 2007-08-23 | 2013-10-08 | The Regents Of The University Of Colorado | Hsp90 inhibitors with modified toxicity |
| US20090258869A1 (en) * | 2008-02-08 | 2009-10-15 | The Regents Of The University Of California | Methods and compounds for treatment or prevention of substance-related disorders |
| EP2321640B1 (fr) | 2008-08-21 | 2016-11-30 | Immunogenics LLC | Formulation pour une administration orale de protéines |
| EP2348845A4 (fr) * | 2008-10-15 | 2013-01-23 | Infinity Pharmaceuticals Inc | Compositions d'ansamycine hydroquinone |
| US20120108563A1 (en) * | 2009-05-19 | 2012-05-03 | Infinity Pharmaceuticals, Inc. | Methods Of Treating Liposarcoma |
| AR077405A1 (es) | 2009-07-10 | 2011-08-24 | Sanofi Aventis | Derivados del indol inhibidores de hsp90, composiciones que los contienen y utilizacion de los mismos para el tratamiento del cancer |
| FR2949467B1 (fr) | 2009-09-03 | 2011-11-25 | Sanofi Aventis | Nouveaux derives de 5,6,7,8-tetrahydroindolizine inhibiteurs d'hsp90, compositions les contenant et utilisation |
| US8945627B2 (en) | 2011-05-05 | 2015-02-03 | Wisconsin Alumni Research Foundation | Micelles for the solubilization of gossypol |
| WO2013074695A1 (fr) | 2011-11-14 | 2013-05-23 | The Regents Of The University Of Colorado, A Body Corporate | Inhibiteurs de hsp90 ayant une toxicité modifiée |
| US10682415B2 (en) | 2013-07-22 | 2020-06-16 | Wisconsin Alumni Research Foundation | Thermogel formulation for combination drug delivery |
| BR112016022593B1 (pt) | 2014-05-01 | 2022-04-26 | Ionis Pharmaceuticals, Inc | Compostos oligoméricos, composições que os compreendem, e usos dos mesmos |
| CN114259564B (zh) * | 2021-11-30 | 2023-03-14 | 清华大学 | Hsp90抑制剂阻碍stat3线粒体转运和治疗哮喘的新应用 |
| CN115227692A (zh) * | 2022-09-05 | 2022-10-25 | 中国医学科学院基础医学研究所 | Reblastatin在制备治疗慢性惊厥的药物中的用途 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4261989A (en) * | 1979-02-19 | 1981-04-14 | Kaken Chemical Co. Ltd. | Geldanamycin derivatives and antitumor drug |
| DE3234203A1 (de) * | 1981-09-17 | 1983-07-07 | Takeda Chemical Industries, Ltd., Osaka | Macbecin-derivate und deren herstellung |
| US4762857A (en) * | 1986-05-30 | 1988-08-09 | E. I. Du Pont De Nemours And Company | Trehalose as stabilizer and tableting excipient |
| JPH06510913A (ja) * | 1992-01-06 | 1994-12-08 | フアイザー・インコーポレイテツド | ４，５‐ジヒドロゲルダナマイシン及びそのヒドロキノンの製造及び使用 |
| US5387584A (en) * | 1993-04-07 | 1995-02-07 | Pfizer Inc. | Bicyclic ansamycins |
| JP2794342B2 (ja) * | 1993-06-29 | 1998-09-03 | ファイザー・インク． | 抗癌遺伝子剤および抗癌剤としてのアンサマイシン誘導体 |
| US5932566A (en) * | 1994-06-16 | 1999-08-03 | Pfizer Inc. | Ansamycin derivatives as antioncogene and anticancer agents |
| KR100831133B1 (ko) * | 2001-03-30 | 2008-05-20 | 더 가브먼트 오브 더 유나이티드 스테이츠 오브 아메리카, 리프리젠티드 바이 더 세크러테리, 디파트먼트 오브 헬쓰 앤드 휴먼 서비씨즈 | 겔다나마이신 유도체 및 그를 사용하는 암 치료 방법 |
| US6872715B2 (en) * | 2001-08-06 | 2005-03-29 | Kosan Biosciences, Inc. | Benzoquinone ansamycins |
| WO2003013430A2 (fr) * | 2001-08-06 | 2003-02-20 | Kosan Biosciences, Inc. | Ansamycine benzoquinone |
| EP1472230B1 (fr) * | 2002-02-08 | 2009-06-17 | Conforma Therapeutic Corporation | Ansamycines a proprietes pharmacologiques et biologiques ameliorees |
| BRPI0418147A (pt) * | 2003-12-23 | 2007-04-17 | Infinity Pharmaceuticals Inc | análogos de ansamicinas contendo benzoquinona e seus métodos de uso |
| US7608611B2 (en) * | 2005-03-11 | 2009-10-27 | The Regents Of The University Of Colorado | Hsp90 inhibitors, methods of making and uses therefor |
-
2005
- 2005-07-13 US US11/180,314 patent/US20060019941A1/en not_active Abandoned
-
2006
- 2006-07-13 AT AT06787067T patent/ATE451919T1/de not_active IP Right Cessation
- 2006-07-13 BR BRPI0612870-0A patent/BRPI0612870A2/pt not_active IP Right Cessation
- 2006-07-13 CA CA002612506A patent/CA2612506A1/fr not_active Abandoned
- 2006-07-13 DE DE602006011161T patent/DE602006011161D1/de active Active
- 2006-07-13 ES ES06787067T patent/ES2337397T3/es active Active
- 2006-07-13 ZA ZA200800906A patent/ZA200800906B/xx unknown
- 2006-07-13 KR KR1020087003410A patent/KR20080030093A/ko not_active Withdrawn
- 2006-07-13 JP JP2008521582A patent/JP2009501234A/ja active Pending
- 2006-07-13 CN CNA2006800335526A patent/CN101267816A/zh active Pending
- 2006-07-13 EP EP06787067A patent/EP1904057B1/fr active Active
- 2006-07-13 MX MX2007016469A patent/MX2007016469A/es not_active Application Discontinuation
- 2006-07-13 AU AU2006268196A patent/AU2006268196A1/en not_active Abandoned
- 2006-07-13 WO PCT/US2006/027113 patent/WO2007009007A2/fr active Application Filing
-
2007
- 2007-12-24 IL IL188355A patent/IL188355A0/en unknown
-
2008
- 2008-01-16 NO NO20080304A patent/NO20080304L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| CA2612506A1 (fr) | 2007-01-18 |
| DE602006011161D1 (de) | 2010-01-28 |
| WO2007009007A2 (fr) | 2007-01-18 |
| ATE451919T1 (de) | 2010-01-15 |
| ZA200800906B (en) | 2009-07-29 |
| MX2007016469A (es) | 2008-04-22 |
| JP2009501234A (ja) | 2009-01-15 |
| EP1904057B1 (fr) | 2009-12-16 |
| WO2007009007A3 (fr) | 2007-05-03 |
| AU2006268196A1 (en) | 2007-01-18 |
| ES2337397T3 (es) | 2010-04-23 |
| KR20080030093A (ko) | 2008-04-03 |
| IL188355A0 (en) | 2008-08-07 |
| BRPI0612870A2 (pt) | 2010-11-30 |
| CN101267816A (zh) | 2008-09-17 |
| US20060019941A1 (en) | 2006-01-26 |
| EP1904057A2 (fr) | 2008-04-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC2A | Withdrawal, rejection or dismissal of laid open patent application |