NO20072665L - Rapamycinderivater og deres anvendelse i behandling av nevrologiske lidelser - Google Patents
Rapamycinderivater og deres anvendelse i behandling av nevrologiske lidelserInfo
- Publication number
- NO20072665L NO20072665L NO20072665A NO20072665A NO20072665L NO 20072665 L NO20072665 L NO 20072665L NO 20072665 A NO20072665 A NO 20072665A NO 20072665 A NO20072665 A NO 20072665A NO 20072665 L NO20072665 L NO 20072665L
- Authority
- NO
- Norway
- Prior art keywords
- neurological disorders
- treatment
- rapamycin derivatives
- compounds
- rapamycin
- Prior art date
Links
- 208000012902 Nervous system disease Diseases 0.000 title abstract 3
- 208000025966 Neurological disease Diseases 0.000 title abstract 2
- QFJCIRLUMZQUOT-HPLJOQBZSA-N sirolimus Chemical class C1C[C@@H](O)[C@H](OC)C[C@@H]1C[C@@H](C)[C@H]1OC(=O)[C@@H]2CCCCN2C(=O)C(=O)[C@](O)(O2)[C@H](C)CC[C@H]2C[C@H](OC)/C(C)=C/C=C/C=C/[C@@H](C)C[C@@H](C)C(=O)[C@H](OC)[C@H](O)/C(C)=C/[C@@H](C)C(=O)C1 QFJCIRLUMZQUOT-HPLJOQBZSA-N 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 2
- 206010019196 Head injury Diseases 0.000 abstract 1
- 230000000626 neurodegenerative effect Effects 0.000 abstract 1
- 230000000324 neuroprotective effect Effects 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
- C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D223/16—Benzazepines; Hydrogenated benzazepines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
- C07D498/18—Bridged systems
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Diabetes (AREA)
- Psychiatry (AREA)
- Addiction (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Hematology (AREA)
- Pain & Pain Management (AREA)
- Obesity (AREA)
- Urology & Nephrology (AREA)
- Psychology (AREA)
- Heart & Thoracic Surgery (AREA)
- Gynecology & Obstetrics (AREA)
- Pulmonology (AREA)
- Cardiology (AREA)
- Hospice & Palliative Care (AREA)
- Child & Adolescent Psychology (AREA)
- Anesthesiology (AREA)
- Emergency Medicine (AREA)
- Pregnancy & Childbirth (AREA)
- Vascular Medicine (AREA)
- Nutrition Science (AREA)
- Epidemiology (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US63800404P | 2004-12-20 | 2004-12-20 | |
PCT/US2005/045331 WO2006068905A2 (fr) | 2004-12-20 | 2005-12-15 | Derives de paramycine et leurs utilisations dans le traitement de troubles neurologiques |
Publications (1)
Publication Number | Publication Date |
---|---|
NO20072665L true NO20072665L (no) | 2007-09-07 |
Family
ID=36602218
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20072665A NO20072665L (no) | 2004-12-20 | 2007-05-25 | Rapamycinderivater og deres anvendelse i behandling av nevrologiske lidelser |
Country Status (16)
Country | Link |
---|---|
US (3) | US7273874B2 (fr) |
EP (1) | EP1828203A2 (fr) |
JP (1) | JP2008524232A (fr) |
KR (1) | KR20070090931A (fr) |
CN (1) | CN101084226A (fr) |
AU (1) | AU2005319427B2 (fr) |
BR (1) | BRPI0519593A2 (fr) |
CA (1) | CA2590254A1 (fr) |
CR (1) | CR9149A (fr) |
IL (1) | IL183772A0 (fr) |
MX (1) | MX2007007409A (fr) |
NI (1) | NI200700156A (fr) |
NO (1) | NO20072665L (fr) |
RU (1) | RU2007119585A (fr) |
WO (1) | WO2006068905A2 (fr) |
ZA (1) | ZA200705123B (fr) |
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GT200500368A (es) * | 2004-12-20 | 2006-07-13 | Analogos de rapamicina y los usos de los mismos en el tratamiento de trastornos neurologicos, proliferativos e inflamatorios | |
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EP1859274A2 (fr) * | 2005-03-07 | 2007-11-28 | Novartis AG | Genes associes a des etats neurodegeneratifs |
WO2007067560A2 (fr) * | 2005-12-07 | 2007-06-14 | Wyeth | Procede evolutif pour la preparation d'un 42-ester de rapamycine a partir d'un borate de 42-ester de rapamycine |
AU2006322030A1 (en) * | 2005-12-07 | 2007-06-14 | Wyeth | Methods for preparing crystalline rapamycin and for measuring crystallinity of rapamycin compounds using differential scanning calorimetry |
BRPI0619493A2 (pt) * | 2005-12-07 | 2016-09-06 | Wyeth Corp | forma cristalina purificada de cci-779, processo para a purificação de cc-779, produto, método para monitorar a cristalização de cci-779, kit, composição farmacêutica, método para o tratamento de câncer, e, uso de um cci-779 purificado |
AU2007223962A1 (en) | 2006-03-07 | 2007-09-13 | Wyeth | Meridamycin analogues for the treatment of neurodegenerative disorders |
TW200824713A (en) * | 2006-10-18 | 2008-06-16 | Wyeth Corp | Processes for the synthesis of individual isomers of mono-PEG CCI-779 |
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EP2077853A1 (fr) * | 2007-01-29 | 2009-07-15 | Wyeth | Ligands d'immunophilines et procedes pour moduler l'activite des immunophilines et des canaux calciques |
JP2008305262A (ja) * | 2007-06-08 | 2008-12-18 | Konica Minolta Business Technologies Inc | サーバ及びシンクライアント環境でのプリンタ紹介方法 |
RU2499599C2 (ru) | 2007-09-28 | 2013-11-27 | Интрексон Корпорейшн | Конструкции терапевтического переключения генов и биореакторы для экспрессии биотерапевтических молекул и их применение |
WO2009105510A1 (fr) * | 2008-02-19 | 2009-08-27 | Wyeth | Procédés d’utilisation d’analogues de la rapamycine pour le traitement de troubles neurologiques |
WO2010024898A2 (fr) | 2008-08-29 | 2010-03-04 | Lutonix, Inc. | Procédés et appareils pour poser un revêtement sur des cathéters à ballonnet |
CN104042612A (zh) | 2008-11-11 | 2014-09-17 | 得克萨斯大学体系董事会 | 哺乳动物雷帕霉素靶蛋白的抑制 |
DE102008060549A1 (de) | 2008-12-04 | 2010-06-10 | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. | Wirkstoff-Peptid-Konstrukt zur extrazellulären Anreicherung |
US9283211B1 (en) | 2009-11-11 | 2016-03-15 | Rapamycin Holdings, Llc | Oral rapamycin preparation and use for stomatitis |
CN103038343A (zh) | 2010-03-23 | 2013-04-10 | 英特瑞克斯顿股份有限公司 | 条件表达治疗蛋白的载体,包含所述载体的宿主细胞,及其应用 |
ES2372077B2 (es) * | 2010-06-24 | 2012-05-18 | Universidad De Sevilla | Uso de la rapamicina para el tratamiento de los déficits cognitivos asociados al s�?ndrome de down. |
WO2012122025A2 (fr) | 2011-03-04 | 2012-09-13 | Intrexon Corporation | Vecteurs exprimant une protéine de façon conditionnelle |
CN102274219A (zh) * | 2011-06-27 | 2011-12-14 | 苏州大学附属第一医院 | 雷帕霉素在治疗蛛网膜下腔出血早期脑损伤的应用 |
CA2926747A1 (fr) | 2012-10-12 | 2014-04-17 | Arlan RICHARDSON | Utilisation d'inhibiteurs mtor pour traiter le deficit cognitif vasculaire |
US9121859B2 (en) * | 2012-12-04 | 2015-09-01 | Siemens Healthcare Diagnostics Inc. | Compounds and methods for determination of FKBP-binding immunosuppressant drugs |
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DK3089737T3 (da) | 2013-12-31 | 2021-12-13 | Rapamycin Holdings Llc | Orale rapamycin-nanopartikelpræparater og anvendelse. |
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DE1545824A1 (de) | 1965-06-21 | 1969-12-11 | Bayer Ag | Verfahren zur Herstellung von 2-Sulfonamido- bzw. 2-Sulfonhydrazido-Benzoxazinonen |
CA930734A (en) | 1969-08-11 | 1973-07-24 | Bickel Hans | Antibiotically active rifamycin compounds and processes for their manufacture |
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-
2005
- 2005-12-15 CN CNA2005800437050A patent/CN101084226A/zh active Pending
- 2005-12-15 KR KR1020077013852A patent/KR20070090931A/ko not_active Withdrawn
- 2005-12-15 AU AU2005319427A patent/AU2005319427B2/en not_active Ceased
- 2005-12-15 CA CA002590254A patent/CA2590254A1/fr not_active Abandoned
- 2005-12-15 RU RU2007119585/04A patent/RU2007119585A/ru not_active Application Discontinuation
- 2005-12-15 BR BRPI0519593-4A patent/BRPI0519593A2/pt not_active IP Right Cessation
- 2005-12-15 WO PCT/US2005/045331 patent/WO2006068905A2/fr active Application Filing
- 2005-12-15 JP JP2007546876A patent/JP2008524232A/ja active Pending
- 2005-12-15 EP EP05854115A patent/EP1828203A2/fr not_active Withdrawn
- 2005-12-15 US US11/300,941 patent/US7273874B2/en not_active Expired - Fee Related
- 2005-12-15 MX MX2007007409A patent/MX2007007409A/es active IP Right Grant
-
2007
- 2007-05-24 CR CR9149A patent/CR9149A/es not_active Application Discontinuation
- 2007-05-25 NO NO20072665A patent/NO20072665L/no not_active Application Discontinuation
- 2007-06-07 IL IL183772A patent/IL183772A0/en unknown
- 2007-06-18 NI NI200700156A patent/NI200700156A/es unknown
- 2007-06-19 ZA ZA200705123A patent/ZA200705123B/xx unknown
- 2007-08-14 US US11/891,879 patent/US7476678B2/en not_active Expired - Fee Related
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2008
- 2008-12-05 US US12/329,106 patent/US20090088448A1/en not_active Abandoned
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---|---|
US20080027089A1 (en) | 2008-01-31 |
NI200700156A (es) | 2008-06-17 |
US20090088448A1 (en) | 2009-04-02 |
EP1828203A2 (fr) | 2007-09-05 |
WO2006068905A3 (fr) | 2006-12-07 |
WO2006068905A2 (fr) | 2006-06-29 |
US7273874B2 (en) | 2007-09-25 |
CN101084226A (zh) | 2007-12-05 |
KR20070090931A (ko) | 2007-09-06 |
ZA200705123B (en) | 2010-01-27 |
CR9149A (es) | 2007-10-23 |
MX2007007409A (es) | 2007-07-12 |
AU2005319427B2 (en) | 2011-11-03 |
BRPI0519593A2 (pt) | 2009-02-25 |
JP2008524232A (ja) | 2008-07-10 |
IL183772A0 (en) | 2007-09-20 |
AU2005319427A1 (en) | 2006-06-29 |
US7476678B2 (en) | 2009-01-13 |
RU2007119585A (ru) | 2009-01-27 |
CA2590254A1 (fr) | 2006-06-29 |
US20060135550A1 (en) | 2006-06-22 |
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