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NO20071634L - Effektiv syntese av 4,5-dihydro-pyrazolo(3,4-C)pyrid-2-oner - Google Patents

Effektiv syntese av 4,5-dihydro-pyrazolo(3,4-C)pyrid-2-oner

Info

Publication number
NO20071634L
NO20071634L NO20071634A NO20071634A NO20071634L NO 20071634 L NO20071634 L NO 20071634L NO 20071634 A NO20071634 A NO 20071634A NO 20071634 A NO20071634 A NO 20071634A NO 20071634 L NO20071634 L NO 20071634L
Authority
NO
Norway
Prior art keywords
pyrid
pyrazolo
dihydro
ones
efficient synthesis
Prior art date
Application number
NO20071634A
Other languages
English (en)
Inventor
Bang-Chi Chen
Boguslaw M Mudryk
Nicolas Cuniere
Dau-Ming Hsieh
Lucius Rossano
Jing Liang
Huiping Zhang
Rulin Zhao
Bei Wang
Adrian David
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Publication of NO20071634L publication Critical patent/NO20071634L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Diabetes (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

Det er beskrevet en ny fremgangsmåte og mellomprodukter derav for fremstilling av 4,5-dihydro-pyrazolo[3,4-c]pyrid-2-oner av typen vist nedenfor fra passende fenylhydraziner. Disse forbindelsene kan være anvendelige som faktor Xa inhibitorer.
NO20071634A 2004-09-28 2007-03-28 Effektiv syntese av 4,5-dihydro-pyrazolo(3,4-C)pyrid-2-oner NO20071634L (no)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US61375404P 2004-09-28 2004-09-28
US63762304P 2004-12-20 2004-12-20
US11/235,647 US7304157B2 (en) 2004-09-28 2005-09-26 Efficient synthesis of 4,5-dihydro-pyrazolo[3,4-c]pyrid-2-ones
PCT/US2005/034511 WO2006036926A2 (en) 2004-09-28 2005-09-27 Efficient synthesis of 4,5-dihydro-pyrazolo[3,4-c]pyrid-2-ones

Publications (1)

Publication Number Publication Date
NO20071634L true NO20071634L (no) 2007-06-21

Family

ID=36100112

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20071634A NO20071634L (no) 2004-09-28 2007-03-28 Effektiv syntese av 4,5-dihydro-pyrazolo(3,4-C)pyrid-2-oner

Country Status (11)

Country Link
US (3) US7304157B2 (no)
EP (1) EP1805176A2 (no)
JP (1) JP2008514710A (no)
KR (1) KR20070067176A (no)
AU (1) AU2005289598A1 (no)
BR (1) BRPI0516172A (no)
CA (1) CA2582222A1 (no)
IL (1) IL182147A0 (no)
MX (1) MX2007003427A (no)
NO (1) NO20071634L (no)
WO (1) WO2006036926A2 (no)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI320039B (en) * 2001-09-21 2010-02-01 Lactam-containing compounds and derivatives thereof as factor xa inhibitors
TW200738672A (en) * 2001-12-10 2007-10-16 Bristol Myers Squibb Co Intermediated for the preparation of 4,5-dihydro-pyrazolo [3,4-c] pyrid-2-ones
US20050090476A1 (en) * 2002-01-21 2005-04-28 Arnoldus Maria Van Buggenum Patrick Process for the preparation of 7alpha-methylsteroids
US20060069085A1 (en) * 2004-09-28 2006-03-30 Rulin Zhao Preparation of 4,5-dihydro-pyrazolo[3,4-c]pyrid-2-ones
US7388096B2 (en) * 2004-09-28 2008-06-17 Bristol-Myers Squibb Company Crystalline forms of a factor Xa inhibitor
KR20070087606A (ko) * 2004-12-15 2007-08-28 브리스톨-마이어스 스큅 컴퍼니 인자 ｘａ 억제제의 결정질 형태
FI20070471A0 (fi) * 2007-06-13 2007-06-13 Glykos Finland Oy Ravinnelisäkompositiota
ES2800948T3 (es) * 2014-09-02 2021-01-05 Cspc Zhongqi Pharmaceutical Tech Shijiazhuang Co Ltd Derivados de pirazolo[3,4-c]piridina

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5423698A (en) * 1994-03-30 1995-06-13 Molex Incorporated Electrical connector system for a video display tube yoke
TWI320039B (en) * 2001-09-21 2010-02-01 Lactam-containing compounds and derivatives thereof as factor xa inhibitors
KR100909141B1 (ko) 2001-09-21 2009-07-23 브리스톨-마이어스스퀴브컴파니 인자 Ｘａ 억제제로서의 락탐-함유 화합물 및 그의 유도체
TW200738672A (en) 2001-12-10 2007-10-16 Bristol Myers Squibb Co Intermediated for the preparation of 4,5-dihydro-pyrazolo [3,4-c] pyrid-2-ones
US20060069085A1 (en) * 2004-09-28 2006-03-30 Rulin Zhao Preparation of 4,5-dihydro-pyrazolo[3,4-c]pyrid-2-ones
US7396932B2 (en) * 2004-09-28 2008-07-08 Bristol-Myers Squibb Company Process for preparing 4,5-dihydro-pyrazolo[3,4-c]pyrid-2-ones
US7388096B2 (en) 2004-09-28 2008-06-17 Bristol-Myers Squibb Company Crystalline forms of a factor Xa inhibitor
US20060069260A1 (en) 2004-09-28 2006-03-30 Huiping Zhang Preparation of N-aryl pyridones

Also Published As

Publication number Publication date
KR20070067176A (ko) 2007-06-27
CA2582222A1 (en) 2006-04-06
US7304157B2 (en) 2007-12-04
WO2006036926B1 (en) 2007-03-15
WO2006036926A3 (en) 2007-01-18
AU2005289598A1 (en) 2006-04-06
BRPI0516172A (pt) 2008-08-26
US20070282106A1 (en) 2007-12-06
US7435821B2 (en) 2008-10-14
EP1805176A2 (en) 2007-07-11
US7579472B2 (en) 2009-08-25
JP2008514710A (ja) 2008-05-08
WO2006036926A2 (en) 2006-04-06
MX2007003427A (es) 2007-05-10
US20080009626A1 (en) 2008-01-10
US20060069119A1 (en) 2006-03-30
IL182147A0 (en) 2007-07-24

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