NO20070368L - Virale polymeraseinhibitorer - Google Patents
Virale polymeraseinhibitorerInfo
- Publication number
- NO20070368L NO20070368L NO20070368A NO20070368A NO20070368L NO 20070368 L NO20070368 L NO 20070368L NO 20070368 A NO20070368 A NO 20070368A NO 20070368 A NO20070368 A NO 20070368A NO 20070368 L NO20070368 L NO 20070368L
- Authority
- NO
- Norway
- Prior art keywords
- polymerase inhibitors
- viral polymerase
- diastereoisomer
- hcv
- tautomer
- Prior art date
Links
- 239000003112 inhibitor Substances 0.000 title abstract 2
- 230000003612 virological effect Effects 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 108700008776 hepatitis C virus NS-5 Proteins 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/12—Radicals substituted by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Virology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Engineering & Computer Science (AREA)
- Gastroenterology & Hepatology (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Indole Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US58867004P | 2004-07-16 | 2004-07-16 | |
| PCT/CA2005/001103 WO2006007693A1 (fr) | 2004-07-16 | 2005-07-15 | Inhibiteurs de la polymerase virale |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO20070368L true NO20070368L (no) | 2007-01-30 |
Family
ID=35784831
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20070368A NO20070368L (no) | 2004-07-16 | 2007-01-19 | Virale polymeraseinhibitorer |
Country Status (19)
| Country | Link |
|---|---|
| US (2) | US7241801B2 (fr) |
| EP (1) | EP1771442A4 (fr) |
| JP (1) | JP2008506638A (fr) |
| KR (1) | KR20070035092A (fr) |
| CN (1) | CN1984908A (fr) |
| AR (1) | AR050172A1 (fr) |
| AU (1) | AU2005263135A1 (fr) |
| BR (1) | BRPI0513431A (fr) |
| CA (1) | CA2573210A1 (fr) |
| EA (1) | EA200700038A1 (fr) |
| EC (1) | ECSP077171A (fr) |
| IL (1) | IL180665A0 (fr) |
| MX (1) | MX2007000007A (fr) |
| NO (1) | NO20070368L (fr) |
| PE (1) | PE20060569A1 (fr) |
| TW (1) | TW200617003A (fr) |
| UY (1) | UY29017A1 (fr) |
| WO (1) | WO2006007693A1 (fr) |
| ZA (1) | ZA200609578B (fr) |
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2335700A1 (fr) * | 2001-07-25 | 2011-06-22 | Boehringer Ingelheim (Canada) Ltd. | Inhibiteurs de la polymerase du virus hepatitis C avec une structure heterobicylic |
| US20050075279A1 (en) * | 2002-10-25 | 2005-04-07 | Boehringer Ingelheim International Gmbh | Macrocyclic peptides active against the hepatitis C virus |
| US7223785B2 (en) | 2003-01-22 | 2007-05-29 | Boehringer Ingelheim International Gmbh | Viral polymerase inhibitors |
| US7098231B2 (en) * | 2003-01-22 | 2006-08-29 | Boehringer Ingelheim International Gmbh | Viral polymerase inhibitors |
| TWI368508B (en) * | 2004-02-20 | 2012-07-21 | Boehringer Ingelheim Int | Viral polymerase inhibitors |
| US7348425B2 (en) | 2004-08-09 | 2008-03-25 | Bristol-Myers Squibb Company | Inhibitors of HCV replication |
| BRPI0606524A2 (pt) * | 2005-01-14 | 2009-06-30 | Genelabs Tech Inc | derivados de indol para o tratamento de infecções virais |
| CA2597680A1 (fr) * | 2005-02-11 | 2006-08-17 | Boehringer Ingelheim International Gmbh | Procede de preparation d'indoles 2,3-disubstitues |
| EP1881828A4 (fr) * | 2005-05-20 | 2009-06-03 | Valeant Res & Dev | Traitement de l'hepatite c (hcv) au moyen de doses sous-therapeutiques de ribavirine |
| CA2618682C (fr) * | 2005-08-12 | 2011-06-21 | Boehringer Ingelheim International Gmbh | Inhibiteurs de polymerase virale |
| FR2896246B1 (fr) | 2006-01-13 | 2008-08-15 | Sanofi Aventis Sa | Derives de pyrido-pyrimidone, leur preparation, leur application en therapeutique. |
| US7816348B2 (en) | 2006-02-03 | 2010-10-19 | Boehringer Ingelheim International Gmbh | Viral polymerase inhibitors |
| WO2007092000A1 (fr) * | 2006-02-06 | 2007-08-16 | Bristol-Myers Squibb Company | Inhibiteurs de réplication du vhc |
| GB0608928D0 (en) | 2006-05-08 | 2006-06-14 | Angeletti P Ist Richerche Bio | Therapeutic agents |
| MX2009000882A (es) | 2006-08-17 | 2009-02-04 | Boehringer Ingelheim Int | Inhibidores de la polimerasa virica. |
| FR2910813B1 (fr) | 2006-12-28 | 2009-02-06 | Sanofi Aventis Sa | Nouvelle utilisation therapeutique pour le traitement des leucemies |
| WO2009008906A2 (fr) | 2007-02-06 | 2009-01-15 | The Trustees Of The University Of Pennsylvania | Composés thérapeutiques pour un blocage de la synthèse d'adn de poxvirus |
| MX2009011930A (es) | 2007-05-04 | 2009-11-18 | Vertex Pharma | Terapia de combinacion para el tratamiento de infeccion de virus de hepatitis c. |
| WO2009010785A1 (fr) | 2007-07-17 | 2009-01-22 | Istituto Di Ricerche Di Biologia Molecolare P. Angeletti Spa | Dérivés macrocycliques d'indole pour le traitement des infections d'hépatite c |
| CA2693997C (fr) | 2007-08-03 | 2013-01-15 | Pierre L. Beaulieu | Inhibiteurs de polymerase virale |
| EP2185539A4 (fr) * | 2007-08-03 | 2011-07-20 | Boehringer Ingelheim Int | Inhibiteurs de polymerase virale |
| MX2010006210A (es) | 2007-12-05 | 2010-08-10 | Enanta Pharm Inc | Inhibidores de serina proteasa de hcv de tripeptido fluorado. |
| EP2234977A4 (fr) | 2007-12-19 | 2011-04-13 | Boehringer Ingelheim Int | Inhibiteurs de polymérase virale |
| WO2010080874A1 (fr) | 2009-01-07 | 2010-07-15 | Scynexis, Inc. | Dérivé de cyclosporine convenant au traitement de l'infection par vhc et vih |
| US8410144B2 (en) | 2009-03-31 | 2013-04-02 | Arqule, Inc. | Substituted indolo-pyridinone compounds |
| JP5639155B2 (ja) | 2009-05-13 | 2014-12-10 | エナンタ ファーマシューティカルズ インコーポレイテッド | Ｃ型肝炎ウイルスインヒビターとしての大環状化合物 |
| KR102128232B1 (ko) | 2010-09-21 | 2020-06-30 | 이난타 파마슈티칼스, 인코포레이티드 | 매크로사이클릭 프롤린 유도된 ｈｃｖ 세린 프로테아제 억제제 |
| US9233921B2 (en) | 2013-03-08 | 2016-01-12 | The Trustees Of The University Of Pennsylvania | Potent poxvirus inhibitor |
| CN113444047B (zh) * | 2016-07-20 | 2023-06-16 | 纳莹(上海)生物科技有限公司 | 一种荧光探针及其制备方法和用途 |
| US12060148B2 (en) | 2022-08-16 | 2024-08-13 | Honeywell International Inc. | Ground resonance detection and warning system and method |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6448281B1 (en) | 2000-07-06 | 2002-09-10 | Boehringer Ingelheim (Canada) Ltd. | Viral polymerase inhibitors |
| WO2002070739A2 (fr) | 2001-03-08 | 2002-09-12 | Boehringer Ingelheim (Canada) Ltd | Dosage d'inhibiteurs de la polymerase vhc |
| EP1411928A1 (fr) * | 2001-07-20 | 2004-04-28 | Boehringer Ingelheim (Canada) Ltd. | Inhibiteurs de polymerase virale |
| EP2335700A1 (fr) | 2001-07-25 | 2011-06-22 | Boehringer Ingelheim (Canada) Ltd. | Inhibiteurs de la polymerase du virus hepatitis C avec une structure heterobicylic |
| US7223785B2 (en) | 2003-01-22 | 2007-05-29 | Boehringer Ingelheim International Gmbh | Viral polymerase inhibitors |
-
2005
- 2005-07-14 PE PE2005000809A patent/PE20060569A1/es not_active Application Discontinuation
- 2005-07-14 UY UY29017A patent/UY29017A1/es not_active Application Discontinuation
- 2005-07-15 AR ARP050102935A patent/AR050172A1/es unknown
- 2005-07-15 MX MX2007000007A patent/MX2007000007A/es active IP Right Grant
- 2005-07-15 TW TW094124015A patent/TW200617003A/zh unknown
- 2005-07-15 BR BRPI0513431-5A patent/BRPI0513431A/pt not_active IP Right Cessation
- 2005-07-15 EA EA200700038A patent/EA200700038A1/ru unknown
- 2005-07-15 CN CNA2005800237228A patent/CN1984908A/zh active Pending
- 2005-07-15 CA CA002573210A patent/CA2573210A1/fr not_active Abandoned
- 2005-07-15 KR KR1020077003911A patent/KR20070035092A/ko not_active Withdrawn
- 2005-07-15 US US11/182,987 patent/US7241801B2/en active Active
- 2005-07-15 WO PCT/CA2005/001103 patent/WO2006007693A1/fr active Application Filing
- 2005-07-15 EP EP05768261A patent/EP1771442A4/fr not_active Withdrawn
- 2005-07-15 AU AU2005263135A patent/AU2005263135A1/en not_active Abandoned
- 2005-07-15 JP JP2007520631A patent/JP2008506638A/ja active Pending
-
2006
- 2006-11-17 ZA ZA200609578A patent/ZA200609578B/xx unknown
-
2007
- 2007-01-11 IL IL180665A patent/IL180665A0/en unknown
- 2007-01-16 EC EC2007007171A patent/ECSP077171A/es unknown
- 2007-01-19 NO NO20070368A patent/NO20070368L/no not_active Application Discontinuation
- 2007-05-25 US US11/753,678 patent/US20070249629A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US7241801B2 (en) | 2007-07-10 |
| ZA200609578B (en) | 2008-08-27 |
| WO2006007693A1 (fr) | 2006-01-26 |
| TW200617003A (en) | 2006-06-01 |
| PE20060569A1 (es) | 2006-06-22 |
| AR050172A1 (es) | 2006-10-04 |
| MX2007000007A (es) | 2007-03-07 |
| CN1984908A (zh) | 2007-06-20 |
| KR20070035092A (ko) | 2007-03-29 |
| ECSP077171A (es) | 2007-02-28 |
| UY29017A1 (es) | 2006-02-24 |
| EP1771442A4 (fr) | 2009-12-30 |
| EA200700038A1 (ru) | 2007-08-31 |
| JP2008506638A (ja) | 2008-03-06 |
| EP1771442A1 (fr) | 2007-04-11 |
| BRPI0513431A (pt) | 2008-05-06 |
| CA2573210A1 (fr) | 2006-01-26 |
| US20070249629A1 (en) | 2007-10-25 |
| US20060052418A1 (en) | 2006-03-09 |
| AU2005263135A1 (en) | 2006-01-26 |
| IL180665A0 (en) | 2007-06-03 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC2A | Withdrawal, rejection or dismissal of laid open patent application |