NO20062644L - DPP-IV inhibitorer - Google Patents

DPP-IV inhibitorer

Info

Publication number: NO20062644L
Authority: NO; Norway
Prior art keywords: dpp; inhibitors; compounds; relates; medicament
Prior art date: 2003-12-09

Application number

NO20062644A

Other languages

English (en)

Norwegian (no)

Inventor

Achim Feurer

Paul John Edwards

Meritxell Lopez-Canet

Silvia Cerezo-Galvez

Victor Matassa

Sonja Nordhoff

Meinolf Thiemann

Oliver Hill

Original Assignee

Santhera Pharmaceuticals Ch

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2003-12-09

Filing date

2006-06-08

Publication date

2006-09-07

2006-06-08 Application filed by Santhera Pharmaceuticals Ch filed Critical Santhera Pharmaceuticals Ch

2006-09-07 Publication of NO20062644L publication Critical patent/NO20062644L/no

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/26—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by nitrogen atoms
- C07D211/28—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by nitrogen atoms to which a second hetero atom is attached
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
- C07D207/09—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/397—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having four-membered rings, e.g. azetidine
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
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- A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
- C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D205/04—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/26—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by nitrogen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/34—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Diabetes (AREA)
Hematology (AREA)
Obesity (AREA)
Endocrinology (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Biomedical Technology (AREA)
Physical Education & Sports Medicine (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Urology & Nephrology (AREA)
Rheumatology (AREA)
Immunology (AREA)
Virology (AREA)
Orthopedic Medicine & Surgery (AREA)
Tropical Medicine & Parasitology (AREA)
Communicable Diseases (AREA)
Vascular Medicine (AREA)
Child & Adolescent Psychology (AREA)
Oncology (AREA)
Ophthalmology & Optometry (AREA)
Pain & Pain Management (AREA)
Psychiatry (AREA)
Reproductive Health (AREA)
Emergency Medicine (AREA)

NO20062644A 2003-12-09 2006-06-08 DPP-IV inhibitorer NO20062644L (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP03028211A EP1541143A1 (en)	2003-12-09	2003-12-09	Dpp-iv inhibitors
PCT/EP2004/014040 WO2005056003A1 (en)	2003-12-09	2004-12-09	Dpp-iv inhibitors

Publications (1)

Publication Number	Publication Date
NO20062644L true NO20062644L (no)	2006-09-07

Family

ID=34486147

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO20062644A NO20062644L (no)	2003-12-09	2006-06-08	DPP-IV inhibitorer

Country Status (24)

Country	Link
US (1)	US20080027035A1 (xx)
EP (2)	EP1541143A1 (xx)
JP (1)	JP2007513910A (xx)
KR (1)	KR100845397B1 (xx)
CN (1)	CN1905868A (xx)
AT (1)	ATE372767T1 (xx)
AU (1)	AU2004296553B2 (xx)
BR (1)	BRPI0417458A (xx)
CA (1)	CA2548742A1 (xx)
CY (1)	CY1106969T1 (xx)
DE (1)	DE602004008895T2 (xx)
DK (1)	DK1613304T3 (xx)
ES (1)	ES2291966T3 (xx)
HK (1)	HK1087022A1 (xx)
HR (1)	HRP20070560T3 (xx)
IL (1)	IL176062A0 (xx)
MX (1)	MXPA06006652A (xx)
NO (1)	NO20062644L (xx)
PL (1)	PL1613304T3 (xx)
PT (1)	PT1613304E (xx)
RU (1)	RU2006119302A (xx)
SI (1)	SI1613304T1 (xx)
WO (1)	WO2005056003A1 (xx)
ZA (1)	ZA200604719B (xx)

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KR20040015298A (ko)	2001-06-27	2004-02-18	스미스클라인 비참 코포레이션	디펩티딜 펩티다제 억제제로서의 플루오로피롤리딘
AU2004206812A1 (en)	2003-01-17	2004-08-05	Merck & Co., Inc.	3-amino-4-phenylbutanoic acid derivatives as dipeptidyl peptidase inhibitors for the treatment or prevention of diabetes
CA2513684A1 (en)	2003-01-31	2004-08-19	Merck & Co., Inc.	3-amino-4-phenylbutanoic acid derivatives as dipeptidyl peptidase inhibitors for the treatment or prevention of diabetes
CA2524531A1 (en)	2003-05-14	2004-12-02	Merck And Co., Inc.	3-amino-4-phenylbutanoic acid derivatives as dipeptidyl peptidase inhibitors for the treatment or prevention of diabetes
CN1798556A (zh)	2003-06-06	2006-07-05	麦克公司	作为治疗或者预防糖尿病的二肽基肽酶抑制剂的稠合吲哚
CN1809544A (zh)	2003-06-17	2006-07-26	麦克公司	作为二肽基肽酶抑制剂用于治疗或预防糖尿病的环己基甘氨酸衍生物
EP1651623B1 (en)	2003-07-31	2008-12-17	Merck & Co., Inc.	Hexahydrodiazepinones as dipeptidyl peptidase-iv inhibitors for the treatment or prevention of diabetes
US7687492B2 (en)	2004-05-04	2010-03-30	Merck Sharp & Dohme Corp.	1,2,4-Oxadiazole derivatives as dipeptidyl peptidase-IV inhibitors for the treatment or prevention of diabetes
US7671073B2 (en)	2004-05-18	2010-03-02	Merck Sharp & Dohme Corp.	Cyclohexylalanine derivatives as dipeptidyl peptidase-IV inhibitors for the treatment or prevention of diabetes
WO2006098342A1 (en) *	2005-03-16	2006-09-21	Astellas Pharma Inc.	Piperazinyl compounds
EP2487154B1 (en) *	2005-10-31	2013-10-16	Bristol-Myers Squibb Company	Pyrrolidinyl beta-amino amide-based inhibitors of dipeptidyl peptidase IV and methods
GB0526291D0 (en)	2005-12-23	2006-02-01	Prosidion Ltd	Therapeutic method
US20090156465A1 (en)	2005-12-30	2009-06-18	Sattigeri Jitendra A	Derivatives of beta-amino acid as dipeptidyl peptidase-iv inhibitors
US7728146B2 (en)	2006-04-12	2010-06-01	Probiodrug Ag	Enzyme inhibitors
EP1905759A1 (en) *	2006-09-07	2008-04-02	Santhera Pharmaceuticals (Schweiz) AG	N-[1-(3-amino-4-phenyl-butyryl)-4-hydroxy-pyrrolidin-2-ylmethyl}-propionamide and related compounds as dpp-iv inhibitors for the treatment oftype 2 diabetes mellitus
WO2008028662A1 (en) *	2006-09-07	2008-03-13	Santhera Pharmaceuticals (Schweiz) Ag	N-[1-(3-amino-4-phenyl-butyryl)-4-hydroxy-pyrrolidin-2-ylmethyl}-propionamide and related compounds as dpp-iv inhibitors for the treatment of type 2 diabetes mellitus
US8278345B2 (en)	2006-11-09	2012-10-02	Probiodrug Ag	Inhibitors of glutaminyl cyclase
US9126987B2 (en)	2006-11-30	2015-09-08	Probiodrug Ag	Inhibitors of glutaminyl cyclase
KR20080071476A (ko) *	2007-01-30	2008-08-04	주식회사 엘지생명과학	신규한 디펩티딜 펩티데이즈 ｉｖ(ｄｐｐ-ｉｖ) 저해제
EP2142514B1 (en)	2007-04-18	2014-12-24	Probiodrug AG	Thiourea derivatives as glutaminyl cyclase inhibitors
KR101007497B1 (ko) *	2007-04-19	2011-01-12	동아제약주식회사	베타 아미노기를 포함하는 ｄｄｐ－ⅳ 저해제, 이의제조방법 및 이를 유효성분으로 함유하는 당뇨 또는 비만예방 및 치료용 약학적 조성물
US7860904B2 (en) *	2007-04-24	2010-12-28	Microsoft Corporation	Standalone execution of incomplete data flows
WO2009003681A1 (en) *	2007-07-02	2009-01-08	Santhera Pharmaceuticals (Schweiz) Ag	Dpp-iv inhibitors
EP2019099A1 (en) *	2007-07-02	2009-01-28	Santhera Pharmaceuticals (Schweiz) AG	Dpp-IV inhibitors
CN102838589B (zh) *	2008-09-23	2014-03-26	成都地奥制药集团有限公司	经甲磺酰化的制备n取代的吡咯烷衍生物的方法
CN101823987B (zh) *	2009-03-06	2014-06-04	中国科学院上海药物研究所	一类新的dpp-ⅳ抑制剂及其制备方法和用途
UA107360C2 (xx)	2009-08-05	2014-12-25	Biogen Idec Inc	Біциклічні арильні аналоги сфінгозин 1-фосфату
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2003
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2004
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- 2004-12-09 CN CNA2004800404476A patent/CN1905868A/zh active Pending
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2006
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Publication number	Publication date
SI1613304T1 (sl)	2007-12-31
CY1106969T1 (el)	2012-09-26
KR100845397B1 (ko)	2008-07-09
EP1613304B1 (en)	2007-09-12
PT1613304E (pt)	2007-11-14
ZA200604719B (en)	2007-12-27
RU2006119302A (ru)	2008-01-20
ES2291966T3 (es)	2008-03-01
US20080027035A1 (en)	2008-01-31
AU2004296553B2 (en)	2008-09-04
BRPI0417458A (pt)	2007-03-13
DE602004008895T2 (de)	2008-06-19
HK1087022A1 (en)	2006-10-06
JP2007513910A (ja)	2007-05-31
MXPA06006652A (es)	2007-02-20
PL1613304T3 (pl)	2008-02-29
EP1613304A1 (en)	2006-01-11
CN1905868A (zh)	2007-01-31
WO2005056003A1 (en)	2005-06-23
IL176062A0 (en)	2006-10-05
HRP20070560T3 (en)	2008-01-31
CA2548742A1 (en)	2005-06-23
DK1613304T3 (da)	2008-01-21
KR20060108756A (ko)	2006-10-18
ATE372767T1 (de)	2007-09-15
DE602004008895D1 (en)	2007-10-25
EP1541143A1 (en)	2005-06-15
AU2004296553A1 (en)	2005-06-23

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Publication	Publication Date	Title
NO20062644L (no)	2006-09-07	DPP-IV inhibitorer
DK1814846T3 (da)	2009-06-22	11beta-HSD1-inhibitorer
NO20070089L (no)	2007-01-05	DPP-IV inhibitorer
ZA200309887B (en)	2004-07-20	Novel compounds as anti-inflammatory, immunomodulatory and anti-proliferatory agents.
MXPA03011039A (es)	2004-03-19	Nuevos compuestos heterociclicos, su preparacion y uso como medicamentos, particularmente como agentes anti-bacterianos.
MX2007000505A (es)	2007-06-25	Derivados de oxindol sustituidos y medicamentos que contienen los mismos.
BR0314688A (pt)	2005-08-02	Novos derivados de piperidina para utilização no tratamento de estados de doença mediados pela quimiocina
NO20034291D0 (no)	2003-09-25	2-aminopropanolderivater
EP1604989A8 (en)	2006-03-15	DPP-IV inhibitors
SE0102616D0 (sv)	2001-07-25	Novel compounds
HK1155146A1 (zh)	2012-05-11	作為藥物活性劑的茚衍生物
IL183636A0 (en)	2007-09-20	Quinoline derivative, use and production thereof, and drug containing the same
DE50202504D1 (de)	2005-04-21	Neue 4-aminofuropyrimidine und ihre verwendung
NO20043016L (no)	2004-07-15	6-aminomorfinan-derivater, fremgangsmate for fremstilling og anvendelse derav
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MX2008001778A (es)	2008-04-07	Combinacion de un agente hipnotico y un compuesto de bis arilo y heteroarilo sustituido y aplicacion terapeutica de la misma.
DE502005008057D1 (de)	2009-10-15	Substituierte cyclopenten-verbindungen
CY1107101T1 (el)	2012-10-24	Μεθοδος συνθεσης παραγωγων της 1,3-διϋδρο-2h-3-βενζαζεπιν-2-ονης και εφαρμογη στη συνθεση της ιβαβραδινης και των αλατων προσθηκης με φαρμακευτικως αποδεκτο οξυ
EA200600608A1 (ru)	2006-10-27	Производные имидазопиридина как ингибиторы индуцируемой no-синтазы
WO2003014094A3 (de)	2003-06-05	Heterocyclylarylsulfonamide
ATE374751T1 (de)	2007-10-15	3,4-dihydro-1h-chinolin-2-onderivate als norepinephrin-wiederaufnahme-hemmern
MXPA04002640A (es)	2004-06-07	Esteres de analogos de 3-desoxi-vitamina d3.
ATE334977T1 (de)	2006-08-15	Discodermolid-analoga und ihre pharmazeutische verwendung
DE60202575D1 (de)	2005-02-17	3,4-Dihydro-1H-Naphthalin-Derivate als hoch selektive Cyclooxygenase-2-Inhibitoren