+

NO20060093L - Plate glykoprotein IB alfa-variant fusjonspolypeptider og fremgangsmater for anvendelse derav - Google Patents

Plate glykoprotein IB alfa-variant fusjonspolypeptider og fremgangsmater for anvendelse derav

Info

Publication number
NO20060093L
NO20060093L NO20060093A NO20060093A NO20060093L NO 20060093 L NO20060093 L NO 20060093L NO 20060093 A NO20060093 A NO 20060093A NO 20060093 A NO20060093 A NO 20060093A NO 20060093 L NO20060093 L NO 20060093L
Authority
NO
Norway
Prior art keywords
methods
glycoprotein
plate
fusion polypeptides
variant fusion
Prior art date
Application number
NO20060093A
Other languages
English (en)
Norwegian (no)
Inventor
Gray D Shaw
Ravindra Kumar
Dianne S Sako
Jin Xu
Original Assignee
Wyeth Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth Corp filed Critical Wyeth Corp
Publication of NO20060093L publication Critical patent/NO20060093L/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745Blood coagulation or fibrinolysis factors
    • C07K14/755Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62DNA sequences coding for fusion proteins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Physics & Mathematics (AREA)
  • Cardiology (AREA)
  • Hematology (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Cell Biology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Diabetes (AREA)
  • Epidemiology (AREA)
  • Vascular Medicine (AREA)
  • Peptides Or Proteins (AREA)
NO20060093A 2003-06-11 2006-01-06 Plate glykoprotein IB alfa-variant fusjonspolypeptider og fremgangsmater for anvendelse derav NO20060093L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US47752503P 2003-06-11 2003-06-11
PCT/US2004/019057 WO2004111089A2 (fr) 2003-06-11 2004-06-14 Polypeptides de fusion de variants de glycoproteines ib-$g(a) de plaquette et leurs methodes

Publications (1)

Publication Number Publication Date
NO20060093L true NO20060093L (no) 2006-03-01

Family

ID=33551724

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20060093A NO20060093L (no) 2003-06-11 2006-01-06 Plate glykoprotein IB alfa-variant fusjonspolypeptider og fremgangsmater for anvendelse derav

Country Status (16)

Country Link
US (2) US7727535B2 (fr)
EP (2) EP1636266A2 (fr)
JP (1) JP2007537710A (fr)
KR (1) KR20060022261A (fr)
CN (1) CN100436480C (fr)
AU (1) AU2004247737B2 (fr)
BR (1) BRPI0411289A (fr)
CA (1) CA2530972A1 (fr)
HK (1) HK1095152A1 (fr)
IL (2) IL172337A (fr)
MX (1) MXPA05013509A (fr)
NO (1) NO20060093L (fr)
NZ (1) NZ544165A (fr)
RU (1) RU2403262C2 (fr)
WO (1) WO2004111089A2 (fr)
ZA (1) ZA200510331B (fr)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7534595B2 (en) * 2006-06-12 2009-05-19 Biomarin Pharmaceutical Inc. Compositions of prokaryotic phenylalanine ammonia-lyase and methods of using compositions thereof
WO2008124086A2 (fr) * 2007-04-05 2008-10-16 President And Fellows Of Harvard College Activateurs chimériques, thérapies protéiniques à conception quantitative et leurs utilisations
DE102007031708A1 (de) * 2007-07-06 2009-01-08 Dade Behring Marburg Gmbh Bestimmung der von Willebrand Faktor-Aktivität in Abwesenheit von Ristocetin
WO2009026551A1 (fr) 2007-08-23 2009-02-26 Bloodcenter Of Wisconsin, Inc. Procédés et kits pour mesurer le facteur von willebrand
BR112014011758A2 (pt) * 2011-11-15 2017-05-09 The Walter And Eliza Hall Inst Of Medical Res composição farmacêutica, proteína de fusão, polinucleotídeo, vetor, célula isolada, métodos para produzir uma proteína de fusão, para tratar ou previnir uma doença ou condição, para diagnosticar a suscetibilidade de um indivíduo a desenvolver uma doença ou condição, para determinar uma adequabilidade do indivíduo para ingressar em um experimento de classificação dedroga, e para identificar um agente, uso de uma combinação, e, combinação.
WO2013096932A1 (fr) * 2011-12-23 2013-06-27 Vasculogics, Inc. Compositions et procédés pour le traitement de thrombose et la prolongation de la survie de plaquettes stockées
EP2919013B1 (fr) 2014-03-11 2016-11-02 Siemens Healthcare Diagnostics Products GmbH Procédé de détection de modulateurs de l'interaction GPIb-Thrombine
US10308697B2 (en) 2014-04-30 2019-06-04 President And Fellows Of Harvard College Fusion proteins for treating cancer and related methods
KR20170010863A (ko) 2014-07-01 2017-02-01 화이자 인코포레이티드 이중특이성 이종이량체성 디아바디 및 이의 용도
JP7373993B2 (ja) * 2018-02-20 2023-11-06 エフ. ホフマン-ラ ロシュ アーゲー 組換えGpIbα受容体タンパク質を含む組成物
CN113264995A (zh) * 2021-05-26 2021-08-17 苏州大学 一种血小板GPIbα蛋白相关的抗原表位肽及其应用
WO2023007182A1 (fr) * 2021-07-29 2023-02-02 The University Of Birmingham Inhibiteurs d'interactions de protéines
EP4455160A1 (fr) * 2021-12-15 2024-10-30 Shanghai Synvida Biotechnology Co. Ltd. Produit et méthode de traitement de la thrombocytopénie

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL88308A0 (en) * 1987-11-17 1989-06-30 Scripps Clinic Res Peptides that block the binding of von willebrand factor
US5340727A (en) 1987-11-17 1994-08-23 The Scripps Research Institute GPIbα fragments and recombinant DNA expression vectors
US4899195A (en) * 1988-01-29 1990-02-06 Ushio Denki Method of exposing a peripheral part of wafer
US5225538A (en) 1989-02-23 1993-07-06 Genentech, Inc. Lymphocyte homing receptor/immunoglobulin fusion proteins
US5013556A (en) 1989-10-20 1991-05-07 Liposome Technology, Inc. Liposomes with enhanced circulation time
NZ237244A (en) * 1990-03-02 1992-10-28 Bio Technology General Corp Cloning and production of human von willebrand factor analogues and compositions thereof
US5194743A (en) * 1990-04-06 1993-03-16 Nikon Corporation Device for positioning circular semiconductor wafers
JP2874280B2 (ja) * 1990-05-16 1999-03-24 株式会社ニコン 周縁露光装置及び周縁露光方法
US6136310A (en) 1991-07-25 2000-10-24 Idec Pharmaceuticals Corporation Recombinant anti-CD4 antibodies for human therapy
US5317097A (en) 1991-10-07 1994-05-31 The Research Foundation Of State University Of New York Mutations in the gene encoding the α chain on platelet glycoprotein IB
US6277975B1 (en) 1992-10-23 2001-08-21 Genetics Institute, Inc. Fusions of P-selectin ligand protein and polynucleotides encoding same
US5516964A (en) 1994-01-21 1996-05-14 Sun Company, Inc. (R&M) Hydrocarbon isomerization using solid superacid catalysts comprising platinum metal
TW316322B (fr) * 1995-10-02 1997-09-21 Ushio Electric Inc
JP3237522B2 (ja) * 1996-02-05 2001-12-10 ウシオ電機株式会社 ウエハ周辺露光方法および装置
JP3735921B2 (ja) 1996-02-07 2006-01-18 三菱ウェルファーマ株式会社 GPIb・脂質複合体およびその用途
AU3369999A (en) 1998-04-02 1999-10-25 Genentech Inc. Antibody variants and fragments thereof
WO1999054360A1 (fr) 1998-04-23 1999-10-28 Ajinomoto Co., Inc. Substance possedant une activite antithrombotique et procede de detection de glycokallidine
AR035779A1 (es) 2001-02-06 2004-07-14 Genetics Inst Llc Polipeptidos de fusion derivados de glicoproteina ib alfa de plaqueta y metodos de uso de los mismos

Also Published As

Publication number Publication date
WO2004111089A3 (fr) 2005-05-12
KR20060022261A (ko) 2006-03-09
AU2004247737A1 (en) 2004-12-23
CA2530972A1 (fr) 2004-12-23
HK1095152A1 (en) 2007-04-27
CN100436480C (zh) 2008-11-26
CN1823090A (zh) 2006-08-23
MXPA05013509A (es) 2006-04-05
US20110039780A1 (en) 2011-02-17
RU2403262C2 (ru) 2010-11-10
EP2522677A1 (fr) 2012-11-14
US20050089888A1 (en) 2005-04-28
AU2004247737B2 (en) 2009-04-23
ZA200510331B (en) 2007-03-28
IL172337A (en) 2012-07-31
RU2006100306A (ru) 2006-06-10
EP1636266A2 (fr) 2006-03-22
WO2004111089A2 (fr) 2004-12-23
US7727535B2 (en) 2010-06-01
IL220272A0 (en) 2012-07-31
JP2007537710A (ja) 2007-12-27
NZ544165A (en) 2008-12-24
BRPI0411289A (pt) 2006-08-01

Similar Documents

Publication Publication Date Title
NO20060093L (no) Plate glykoprotein IB alfa-variant fusjonspolypeptider og fremgangsmater for anvendelse derav
ATE350409T1 (de) Ampholytisches copolymer und dessen verwendung
NO20071188L (no) Humaniserte anti-cMet-antagonister
DK3530673T3 (da) Humaniserede anti-beta7-antagonister og anvendelser deraf
BRPI0507118A (pt) polipeptìdeos de interferon humano modificado e seus usos
DE602004026113D1 (de) Glp-1-verbindungen
GB2430677A8 (en) Novel antigenbinding polypeptides and their uses
UA95768C2 (ru) Антагонисты мускариновых рецепторов ацетилхолина
SG158141A1 (en) Pancreatic polypeptide family motifs, polypeptides and methods comprising the same
YU9404A (sh) Multimerna, usmerena kontrastna sredstva na bazi peptida
ATE554114T1 (de) Copolymer mit zwitterionischen einheiten und anderen einheiten, das copolymer umfassende zusammensetzung und verwendung
NO20034056D0 (no) Proliferative sykdommer
ATE335722T1 (de) Benzoylsulfonamide und sulfonylbenzamidine zur verwendung als antitumor-mittel
DK1487493T3 (da) Konjugater af cytotoksiske midler og biologisk aktive peptider
ZA200606620B (en) Methods of modulating IL-23 activity ; related reagents
WO2006137934A3 (fr) Eloignement volontaire de cellules migratoires humaines d'une source d'agents
DK1560812T3 (da) Aminocyclohexyletherforbindelser og anvendelser deraf
ATE409188T1 (de) Naphthyridinverbindungen
WO2003104425A3 (fr) Nouveaux anticorps anti-cd22 stables
ATE496892T1 (de) Tetrahydroisochinolinverbindungen zur behandlung von zns-erkrankungen
DE602004017332D1 (de) Neue kondensierte n-pyrazinyl-sulfonamide und deren verwendung bei der behandlung von chemokinvermittelten krankheiten
NO20075140L (no) Fremgangsmater og preparater for modulering av vaskulaer integritet
NO20011537L (no) Chemokin-reseptorpeptidvaksiner for behandling og forebygging av diabetes
WO2002063003A3 (fr) Polypeptides de fusion de la glycoproteine plaquettaire ib alpha et methodes d'utilisation
ATE363511T1 (de) Trennfilme

Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application
点击 这是indexloc提供的php浏览器服务,不要输入任何密码和下载