NO20033660L - HIV inhibitere N-aminoimidazolderivativer - Google Patents

HIV inhibitere N-aminoimidazolderivativer

Info

Publication number: NO20033660L
Authority: NO; Norway
Prior art keywords: sup; pyrimidyl; pyridyl; naphtyl; methyl
Prior art date: 2001-02-23

Application number

NO20033660A

Other languages

English (en)

Norwegian (no)

Other versions

NO20033660D0 (no

Inventor

Erik De Clercq

Arthur Van Aerschot

Piet Herdewijn

Irene Lagoja

Christophe Pannecoucque

Original Assignee

Leuven K U Res & Dev

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-02-23

Filing date

2003-08-19

Publication date

2003-10-15

2003-08-19 Application filed by Leuven K U Res & Dev filed Critical Leuven K U Res & Dev

2003-08-19 Publication of NO20033660D0 publication Critical patent/NO20033660D0/no

2003-10-15 Publication of NO20033660L publication Critical patent/NO20033660L/no

Links

MXZANEWAFZMPKW-UHFFFAOYSA-N imidazol-1-amine Chemical class NN1C=CN=C1 MXZANEWAFZMPKW-UHFFFAOYSA-N 0.000 title abstract 2
-1 2-pyrimidyl Chemical group 0.000 abstract 6
ZUOUZKKEUPVFJK-UHFFFAOYSA-N diphenyl Chemical compound C1=CC=CC=C1C1=CC=CC=C1 ZUOUZKKEUPVFJK-UHFFFAOYSA-N 0.000 abstract 4
229910052739 hydrogen Inorganic materials 0.000 abstract 4
125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 4
125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 abstract 3
125000004105 2-pyridyl group Chemical group N1=C([*])C([H])=C([H])C([H])=C1[H] 0.000 abstract 2
125000003349 3-pyridyl group Chemical group N1=C([H])C([*])=C([H])C([H])=C1[H] 0.000 abstract 2
125000000339 4-pyridyl group Chemical group N1=C([H])C([H])=C([*])C([H])=C1[H] 0.000 abstract 2
235000010290 biphenyl Nutrition 0.000 abstract 2
239000004305 biphenyl Substances 0.000 abstract 2
239000001257 hydrogen Substances 0.000 abstract 2
125000004435 hydrogen atom Chemical class [H]* 0.000 abstract 2
125000001449 isopropyl group Chemical group [H]C([H])([H])C([H])(*)C([H])([H])[H] 0.000 abstract 2
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
125000001424 substituent group Chemical group 0.000 abstract 2
238000006467 substitution reaction Methods 0.000 abstract 2
125000001544 thienyl group Chemical group 0.000 abstract 2
FMXYWAWAIGUHRZ-UHFFFAOYSA-N 3-amino-1h-imidazole-2-thione Chemical class NN1C=CNC1=S FMXYWAWAIGUHRZ-UHFFFAOYSA-N 0.000 abstract 1
208000036142 Viral infection Diseases 0.000 abstract 1
125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 1
230000004071 biological effect Effects 0.000 abstract 1
239000003795 chemical substances by application Substances 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
150000002148 esters Chemical class 0.000 abstract 1
125000002791 glucosyl group Chemical group C1([C@H](O)[C@@H](O)[C@H](O)[C@H](O1)CO)* 0.000 abstract 1
230000013595 glycosylation Effects 0.000 abstract 1
238000006206 glycosylation reaction Methods 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
230000009385 viral infection Effects 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/84—Sulfur atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Chemical & Material Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Virology (AREA)
General Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
AIDS & HIV (AREA)
Tropical Medicine & Parasitology (AREA)
Molecular Biology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Plural Heterocyclic Compounds (AREA)

NO20033660A 2001-02-23 2003-08-19 HIV inhibitere N-aminoimidazolderivativer NO20033660L (no)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
PCT/EP2001/002140 WO2002068395A1 (fr)	2001-02-23	2001-02-23	Derives n-aminoimidazole inhibant le vih

Publications (2)

Publication Number	Publication Date
NO20033660D0 NO20033660D0 (no)	2003-08-19
NO20033660L true NO20033660L (no)	2003-10-15

Family

ID=8164312

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO20033660A NO20033660L (no)	2001-02-23	2003-08-19	HIV inhibitere N-aminoimidazolderivativer

Country Status (22)

Country	Link
US (1)	US7049332B2 (fr)
EP (1)	EP1370539B1 (fr)
JP (1)	JP2004519477A (fr)
KR (1)	KR100732581B1 (fr)
CN (1)	CN1555365A (fr)
AT (1)	ATE532771T1 (fr)
AU (1)	AU2001246474B2 (fr)
BR (1)	BR0116938A (fr)
CA (1)	CA2439053A1 (fr)
CY (1)	CY1113031T1 (fr)
DK (1)	DK1370539T3 (fr)
EA (1)	EA006706B1 (fr)
ES (1)	ES2376998T3 (fr)
HU (1)	HUP0303238A3 (fr)
IL (1)	IL157453A0 (fr)
MX (1)	MXPA03007546A (fr)
NO (1)	NO20033660L (fr)
NZ (1)	NZ527640A (fr)
PL (1)	PL363100A1 (fr)
PT (1)	PT1370539E (fr)
TR (1)	TR200301890T2 (fr)
WO (1)	WO2002068395A1 (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AU2011226950B9 (en) *	2003-12-15	2013-04-11	Laboratoire Theramex	1-N-phenyl-amino-1H-imidazole derivatives and pharmaceutical compositions containing them
MXPA06006837A (es) *	2003-12-15	2006-09-04	Theramex	Derivados de 1-n-fenil-amino-ih-imidazol y composiciones farmaceuticas que los contienen.
EP1544195A1 (fr) *	2003-12-15	2005-06-22	Laboratoire Theramex	Dérivés de 1-N-phenylamino-1H-imidazoles et compositions les contenant
GB0609252D0 (en) *	2006-05-10	2006-06-21	Leuven K U Res & Dev	Novel sytoprotective compounds
US20140194473A1 (en) *	2013-01-10	2014-07-10	E I Du Pont De Nemours And Company	Imidazole fungicides

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
TW235963B (fr)	1992-01-16	1994-12-11	Shionogi & Co
JPH0810019A (ja) *	1994-07-04	1996-01-16	Taiyo Shinjiyu Kk	タグが取り付けられた連珠製品、及び、連珠製品へのタグ取り付け方法
RU2157368C2 (ru) *	1994-09-26	2000-10-10	Сионоги Энд Ко., Лтд.	Производные имидазола и фармацевтическая композиция на их основе

2001
- 2001-02-23 IL IL15745301A patent/IL157453A0/xx unknown
- 2001-02-23 PT PT01919343T patent/PT1370539E/pt unknown
- 2001-02-23 PL PL01363100A patent/PL363100A1/xx not_active Application Discontinuation
- 2001-02-23 MX MXPA03007546A patent/MXPA03007546A/es active IP Right Grant
- 2001-02-23 ES ES01919343T patent/ES2376998T3/es not_active Expired - Lifetime
- 2001-02-23 CN CNA018231675A patent/CN1555365A/zh active Pending
- 2001-02-23 WO PCT/EP2001/002140 patent/WO2002068395A1/fr active IP Right Grant
- 2001-02-23 EP EP01919343A patent/EP1370539B1/fr not_active Expired - Lifetime
- 2001-02-23 BR BR0116938-6A patent/BR0116938A/pt not_active IP Right Cessation
- 2001-02-23 EA EA200300920A patent/EA006706B1/ru not_active IP Right Cessation
- 2001-02-23 JP JP2002567909A patent/JP2004519477A/ja active Pending
- 2001-02-23 HU HU0303238A patent/HUP0303238A3/hu unknown
- 2001-02-23 AT AT01919343T patent/ATE532771T1/de active
- 2001-02-23 AU AU2001246474A patent/AU2001246474B2/en not_active Ceased
- 2001-02-23 TR TR2003/01890T patent/TR200301890T2/xx unknown
- 2001-02-23 US US10/468,541 patent/US7049332B2/en not_active Expired - Fee Related
- 2001-02-23 DK DK01919343.2T patent/DK1370539T3/da active
- 2001-02-23 CA CA002439053A patent/CA2439053A1/fr not_active Abandoned
- 2001-02-23 NZ NZ527640A patent/NZ527640A/en unknown
- 2001-02-23 KR KR1020037011071A patent/KR100732581B1/ko not_active Expired - Fee Related
2003
- 2003-08-19 NO NO20033660A patent/NO20033660L/no not_active Application Discontinuation
2012
- 2012-01-27 CY CY20121100097T patent/CY1113031T1/el unknown

Also Published As

Publication number	Publication date
KR20030086271A (ko)	2003-11-07
CN1555365A (zh)	2004-12-15
NO20033660D0 (no)	2003-08-19
KR100732581B1 (ko)	2007-06-27
AU2001246474B8 (en)	2002-09-12
PL363100A1 (en)	2004-11-15
EP1370539A1 (fr)	2003-12-17
HUP0303238A3 (en)	2004-05-28
US7049332B2 (en)	2006-05-23
CY1113031T1 (el)	2016-04-13
DK1370539T3 (da)	2012-02-13
EA006706B1 (ru)	2006-02-24
JP2004519477A (ja)	2004-07-02
BR0116938A (pt)	2005-01-18
AU2001246474B2 (en)	2007-07-05
ATE532771T1 (de)	2011-11-15
TR200301890T2 (tr)	2004-12-21
MXPA03007546A (es)	2004-10-15
EP1370539B1 (fr)	2011-11-09
CA2439053A1 (fr)	2002-09-06
WO2002068395A1 (fr)	2002-09-06
NZ527640A (en)	2005-10-28
IL157453A0 (en)	2004-03-28
ES2376998T3 (es)	2012-03-21
HUP0303238A2 (hu)	2004-01-28
US20040122024A1 (en)	2004-06-24
PT1370539E (pt)	2012-02-14
EA200300920A1 (ru)	2004-02-26

Legal Events

Date	Code	Title	Description
2009-06-08	FC2A	Withdrawal, rejection or dismissal of laid open patent application

Publication	Publication Date	Title
NO941101L (no)	1994-05-30	Quinazolin-derivater
BRPI0000596B8 (pt)	2021-05-25	composto piridona, processo de produção do composto, composição farmacêutica, e uso do dito composto
DK1063228T5 (da)	2009-06-15	Cycloalkenderivater, fremgangsmåde til fremstilling deraf og anvendelse deraf
NO20072753L (no)	2007-07-17	3-Etylidenhydrazinosubstituerte heterocykliske forbindelser som trombopoietinreseptoraktivatorer
IL100807A (en)	1997-03-18	N-phenylcarbamate compounds, their preparation and fungicidal compositions containing them
CY1113031T1 (el)	2016-04-13	Παραγωγα ν-αμινοϊμιδαζολιου που αναστελουν ηιv
DK1043310T3 (da)	2004-10-25	Biphenylamidinderivater
DK1157998T3 (da)	2004-06-14	Heterocykliske forbindelser, mellemprodukter derfor og elastaseinhibitorer
DE69839753D1 (de)	2008-09-04	2-(Arylphenyl)amino-imidazolin-Derivate
JP2003012667A (ja)	2003-01-15	キノリンカルボキサミド骨格を有する抗菌剤
HRP20010630B1 (en)	2010-08-31	4-heterocyclysulfonamidyl-6-methoxy-5-(2-methoxy-phenoxy)-2-pyridyl-pyrimidine derivatives, their preparation and use as endothelin receptor antagonists
CA2373880A1 (fr)	2000-12-14	Derives de l'isoquinoline ou leurs sels
WO2002062798A3 (fr)	2002-12-05	Sels de composes heterocycliques pharmaceutiquement acceptables
CY1110898T1 (el)	2015-06-10	Νεα παραγωγα πυριδινοκαρβοξυλικου οξεος ή αλατα αυτων
MXPA01008308A (es)	2003-06-06	Proceso para la preparacion de compuestos de 6-(perfluoroalquil) uracilo.
AR036179A1 (es)	2004-08-18	Composicion farmaceutica para el tratamiento de una enfermedad pulmonar obstructiva cronica y uso de un compuesto de tiazol para prepararla
KR970001357A (ko)	1997-01-24	접합고리 피리딘을 함유한 벤즈이미다졸 유도체
JPH0730027B2 (ja)	1995-04-05	５−シアノピリジン−３−カルボキサミド化合物及び植物成長抑制剤
RU94017645A (ru)	1995-12-27	Производные хиназолина и фармацевтическая композиция на их основе
TH62392A (th)	2004-06-07	อนุพันธ์ควิโนลีนและไพริดีนชนิดใหม่