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NO20030301L - Nye heteroarylderivater og anvendelse derav som farmasöytika - Google Patents

Nye heteroarylderivater og anvendelse derav som farmasöytika

Info

Publication number
NO20030301L
NO20030301L NO20030301A NO20030301A NO20030301L NO 20030301 L NO20030301 L NO 20030301L NO 20030301 A NO20030301 A NO 20030301A NO 20030301 A NO20030301 A NO 20030301A NO 20030301 L NO20030301 L NO 20030301L
Authority
NO
Norway
Prior art keywords
pharmaceuticals
heteroaryl derivatives
new heteroaryl
new
derivatives
Prior art date
Application number
NO20030301A
Other languages
English (en)
Other versions
NO324939B1 (no
NO20030301D0 (no
Inventor
Peter Emig
Eckhard Guenther
Silke Baasner
Gerald Bacher
Thomas Beckers
Beate Aue
Original Assignee
Zentaris Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zentaris Ag filed Critical Zentaris Ag
Publication of NO20030301D0 publication Critical patent/NO20030301D0/no
Publication of NO20030301L publication Critical patent/NO20030301L/no
Publication of NO324939B1 publication Critical patent/NO324939B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D219/00—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems
    • C07D219/04—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Nye akridinderivater av generell formel (1). fremgangsmåte for deres fremstilling og anvendelsen derav som farmasøytika, spesielt for behandling av tumorer.
NO20030301A 2000-07-21 2003-01-20 Akridinderivater, anvendelse derav, fremgangsmate for fremstilling derav samt medikament inneholdende minst ett akridinderivat NO324939B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10035927A DE10035927A1 (de) 2000-07-21 2000-07-21 Neue Heteroaryl-Derivate und deren Verwendung als Arzneimittel
PCT/EP2001/008263 WO2002008194A1 (de) 2000-07-21 2001-07-18 Acridin-derivate und deren verwendung als arzneimittel

Publications (3)

Publication Number Publication Date
NO20030301D0 NO20030301D0 (no) 2003-01-20
NO20030301L true NO20030301L (no) 2003-03-11
NO324939B1 NO324939B1 (no) 2008-01-07

Family

ID=7649979

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20030301A NO324939B1 (no) 2000-07-21 2003-01-20 Akridinderivater, anvendelse derav, fremgangsmate for fremstilling derav samt medikament inneholdende minst ett akridinderivat

Country Status (29)

Country Link
US (1) US6706722B2 (no)
EP (1) EP1301485B1 (no)
JP (1) JP2004504382A (no)
KR (1) KR20030022296A (no)
CN (1) CN1296359C (no)
AR (1) AR033383A1 (no)
AT (1) ATE365717T1 (no)
AU (2) AU2001289675B2 (no)
BG (1) BG107507A (no)
BR (1) BR0112591A (no)
CA (1) CA2353360A1 (no)
CY (1) CY1106890T1 (no)
CZ (1) CZ2003427A3 (no)
DE (2) DE10035927A1 (no)
DK (1) DK1301485T3 (no)
ES (1) ES2291349T3 (no)
HK (1) HK1057549A1 (no)
HU (1) HUP0303729A3 (no)
IL (1) IL153476A0 (no)
MX (1) MXPA02012564A (no)
NO (1) NO324939B1 (no)
NZ (1) NZ524155A (no)
PL (1) PL358808A1 (no)
PT (1) PT1301485E (no)
RU (1) RU2267488C2 (no)
SK (1) SK1932003A3 (no)
UA (1) UA75085C2 (no)
WO (1) WO2002008194A1 (no)
ZA (1) ZA200210411B (no)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10035928A1 (de) * 2000-07-21 2002-03-07 Asta Medica Ag Neue Heteroaryl-Derivate und deren Verwendung als Arzneimittel
DE10037310A1 (de) * 2000-07-28 2002-02-07 Asta Medica Ag Neue Indolderivate und deren Verwendung als Arzneimittel
MXPA04012959A (es) * 2002-06-29 2005-05-16 Zentaris Gmbh Arilcarbonilpiperacinas y heteroarilcarbonilpiperacinas y su uso para tratamiento de enfermedades de tumor benigno y maligno.
MXPA05000487A (es) * 2002-07-17 2005-03-23 Zentaris Gmbh Nuevos derivados de antraceno y su uso como un medicamento.
US7125461B2 (en) * 2003-05-07 2006-10-24 L & L Products, Inc. Activatable material for sealing, baffling or reinforcing and method of forming same
FR2855825B1 (fr) * 2003-06-04 2008-08-22 Aventis Pharma Sa Produits aryl-heteroaromatiques, compositions les contenant et utilisation
PE20050226A1 (es) * 2003-06-04 2005-05-18 Aventis Pharma Sa Productos aril-heteroaromaticos y composiciones que los contienen
US7249415B2 (en) * 2003-06-26 2007-07-31 Zephyros, Inc. Method of forming members for sealing or baffling
DE10331500A1 (de) * 2003-07-11 2005-02-24 Zentaris Gmbh Neue Acridin-Derivate und deren Verwendung als Arzneimittel
CA2595994A1 (en) * 2005-01-27 2006-08-03 Alma Mater Studiorum - Universita' Di Bologna Organic compounds useful for the treatment of alzheimer's disease, their use and method of preparation
US20070299093A1 (en) * 2005-01-27 2007-12-27 Alma Mater Studiorum-Universitá Di Bologna Organic Compounds Useful for the Treatment of Alzheimer's Disease, Their Use and Method of Preparation
CA2678577A1 (en) * 2007-02-26 2008-09-04 Vitae Pharmaceuticals, Inc. Cyclic urea and carbamate inhibitors of 11.beta.-hydroxysteroid dehydrogenase 1
ATE554078T1 (de) * 2007-07-26 2012-05-15 Vitae Pharmaceuticals Inc Synthese von 11-beta-hydroxysteroid-dehydrogenase-1-hemmern
AR069207A1 (es) * 2007-11-07 2010-01-06 Vitae Pharmaceuticals Inc Ureas ciclicas como inhibidores de la 11 beta - hidroxi-esteroide deshidrogenasa 1
JP5490014B2 (ja) 2007-12-11 2014-05-14 ヴァイティー ファーマシューティカルズ，インコーポレイテッド １１β−ヒドロキシステロイドデヒドロゲナーゼ１型の環状尿素阻害剤
TW200934490A (en) * 2008-01-07 2009-08-16 Vitae Pharmaceuticals Inc Lactam inhibitors of 11 &abgr;-hydroxysteroid dehydrogenase 1
CA2712500A1 (en) * 2008-01-24 2009-07-30 Vitae Pharmaceuticals, Inc. Cyclic carbazate and semicarbazide inhibitors of 11beta-hydroxysteroid dehydrogenase 1
JP5734666B2 (ja) * 2008-02-11 2015-06-17 ヴァイティー ファーマシューティカルズ，インコーポレイテッド １１β−ヒドロキシステロイドデヒドロゲナーゼ１の１，３−オキサアゼパン−２−オン及び１，３−ジアゼパン−２−オン阻害剤
US8598160B2 (en) * 2008-02-15 2013-12-03 Vitae Pharmaceuticals, Inc. Cycloalkyl lactame derivatives as inhibitors of 11-beta-hydroxysteroid dehydrogenase 1
CA2718264A1 (en) * 2008-03-18 2009-09-24 Vitae Pharmaceuticals, Inc. Inhibitors of 11beta-hydroxysteroid dehydrogenase type 1
EP2291370B1 (en) 2008-05-01 2013-11-27 Vitae Pharmaceuticals, Inc. Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1
NZ588954A (en) * 2008-05-01 2012-08-31 Vitae Pharmaceuticals Inc Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1
EP2291371B1 (en) 2008-05-01 2015-06-10 Vitae Pharmaceuticals, Inc. Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1
JP5451752B2 (ja) * 2008-05-01 2014-03-26 ヴァイティー ファーマシューティカルズ，インコーポレイテッド １１β−ヒドロキシステロイドデヒドロゲナーゼ１の環状インヒビター
ES2432150T3 (es) 2008-07-25 2013-12-02 Boehringer Ingelheim International Gmbh Inhibidores cíclicos de la 11 beta-hidroxiesteroide deshidrogenasa 1
EP2324017B1 (en) 2008-07-25 2014-12-31 Boehringer Ingelheim International GmbH INHIBITORS OF 11beta-HYDROXYSTEROID DEHYDROGENASE 1
CA2744946A1 (en) 2009-02-04 2010-08-12 Boehringer Ingelheim International Gmbh Cyclic inhibitors of 11.beta.-hydroxysteroid dehydrogenase 1
TW201039034A (en) * 2009-04-27 2010-11-01 Chunghwa Picture Tubes Ltd Pixel structure and the method of forming the same
MA33216B1 (fr) 2009-04-30 2012-04-02 Boehringer Ingelheim Int Inhibiteurs cycliques de la 11béta-hydroxysteroïde déshydrogénase 1
US20100331320A1 (en) * 2009-04-30 2010-12-30 Vitae Pharmaceuticals, Inc. Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1
JP5656986B2 (ja) 2009-06-11 2015-01-21 ヴァイティー ファーマシューティカルズ，インコーポレイテッド １，３−オキサジナン−２−オン構造に基づく１１β−ヒドロキシステロイドデヒドロゲナーゼ１の環状阻害剤
JP5749263B2 (ja) 2009-07-01 2015-07-15 ヴァイティー ファーマシューティカルズ，インコーポレイテッド １１β−ヒドロキシステロイドデヒドロゲナーゼ１の環状インヒビター
WO2011159760A1 (en) 2010-06-16 2011-12-22 Vitae Pharmaceuticals, Inc. Substituted 5-,6- and 7-membered heterocycles, medicaments containing such compounds, and their use
WO2011161128A1 (en) 2010-06-25 2011-12-29 Boehringer Ingelheim International Gmbh Azaspirohexanones as inhibitors of 11-beta-hsd1 for the treatment of metabolic disorders
MX2013004699A (es) 2010-11-02 2013-05-22 Boehringer Ingelheim Int Combinaciones farmaceuticas para el tratamiento de trastornos metabolicos.

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2538388B1 (fr) 1982-12-24 1985-06-21 Pharmuka Lab Nouveaux derives de naphtalene- ou azanaphtalenecarboxamide, leurs procedes de preparation et leur utilisation comme medicaments
EP0318235A3 (en) * 1987-11-25 1991-05-02 Takeda Chemical Industries, Ltd. Paf antagonist, 1,4-disubstituted piperazine compounds and production thereof
US5030631A (en) * 1989-11-27 1991-07-09 Schering Corporation Tricylclic arylsulfonamides
RU2126001C1 (ru) * 1995-01-10 1999-02-10 Самдзин Фармасьютикал Ко., Лтд Производные пиперазина и фармацевтическая композиция на их основе
JP3032303B2 (ja) * 1996-06-29 2000-04-17 サムジン ファーマシューチカル カンパニー，リミテッド ピペラジン誘導体及びその製造方法
US5861395A (en) 1996-09-13 1999-01-19 Schering Corporation Compounds useful for inhibition of farnesyl proteins transferase
FR2753706B1 (fr) 1996-09-20 1998-10-30 Nouvelles amines cycliques n-substituees, leur procede de preparation et les compositions pharmaceutiques les renfermant
DE19743435A1 (de) 1997-10-01 1999-04-08 Merck Patent Gmbh Benzamidinderivate
CN1261098C (zh) 1998-08-28 2006-06-28 西奥斯股份有限公司 p38－α激酶的抑制剂
EP1165084A4 (en) 1999-03-03 2002-05-15 Merck & Co Inc PRENYL PROTEIN TRANSFERASES INHIBITORS

Also Published As

Publication number Publication date
DE10035927A1 (de) 2002-03-07
US6706722B2 (en) 2004-03-16
HUP0303729A3 (en) 2009-01-28
CN1443172A (zh) 2003-09-17
CZ2003427A3 (cs) 2003-06-18
BR0112591A (pt) 2003-07-22
CN1296359C (zh) 2007-01-24
AR033383A1 (es) 2003-12-17
BG107507A (bg) 2003-09-30
CY1106890T1 (el) 2012-09-26
AU8967501A (en) 2002-02-05
PT1301485E (pt) 2007-08-30
NO324939B1 (no) 2008-01-07
NO20030301D0 (no) 2003-01-20
EP1301485B1 (de) 2007-06-27
US20020132821A1 (en) 2002-09-19
CA2353360A1 (en) 2002-01-21
ES2291349T3 (es) 2008-03-01
WO2002008194A1 (de) 2002-01-31
IL153476A0 (en) 2003-07-06
EP1301485A1 (de) 2003-04-16
MXPA02012564A (es) 2003-09-22
ZA200210411B (en) 2003-02-26
PL358808A1 (en) 2004-08-23
WO2002008194A8 (de) 2003-05-08
DK1301485T3 (da) 2007-11-05
SK1932003A3 (en) 2003-10-07
JP2004504382A (ja) 2004-02-12
ATE365717T1 (de) 2007-07-15
KR20030022296A (ko) 2003-03-15
HK1057549A1 (en) 2004-04-08
UA75085C2 (en) 2006-03-15
DE50112669D1 (de) 2007-08-09
NZ524155A (en) 2005-04-29
HUP0303729A2 (hu) 2004-03-01
RU2267488C2 (ru) 2006-01-10
AU2001289675B2 (en) 2005-04-07

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