+

NO20003068L - Hydrat av 5-[-4-[2-(N-metyl-N-(2- pyridyl)amino)etoksy]benzyl]tiazolidin-2,4-dion-maleinsyre-salt - Google Patents

Hydrat av 5-[-4-[2-(N-metyl-N-(2- pyridyl)amino)etoksy]benzyl]tiazolidin-2,4-dion-maleinsyre-salt

Info

Publication number
NO20003068L
NO20003068L NO20003068A NO20003068A NO20003068L NO 20003068 L NO20003068 L NO 20003068L NO 20003068 A NO20003068 A NO 20003068A NO 20003068 A NO20003068 A NO 20003068A NO 20003068 L NO20003068 L NO 20003068L
Authority
NO
Norway
Prior art keywords
thiazolidine
dione
pyridyl
hydrate
ethoxy
Prior art date
Application number
NO20003068A
Other languages
English (en)
Other versions
NO317253B1 (no
NO20003068D0 (no
Inventor
Paul David James Blackler
Michael John Sasse
David C Lee
Original Assignee
Smithkline Beecham Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Plc filed Critical Smithkline Beecham Plc
Publication of NO20003068D0 publication Critical patent/NO20003068D0/no
Publication of NO20003068L publication Critical patent/NO20003068L/no
Publication of NO317253B1 publication Critical patent/NO317253B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Diabetes (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
NO20003068A 1997-12-16 2000-06-15 Hydrat av 5-[-4-[2-(N-metyl-N-(2-pyridyl)amino)etoksy]benzyl]tiazolidin-2,4-dion-maleinsyre-salt NO317253B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9726568.0A GB9726568D0 (en) 1997-12-16 1997-12-16 Novel pharmaceutical
PCT/EP1998/008154 WO1999031094A1 (en) 1997-12-16 1998-12-14 Hydrate of 5-[4-[2- (n-methyl-n- (2-pyridil)amino) ethoxy]benzyl] thiazolidine-2, 4-dione maleic acid salt

Publications (3)

Publication Number Publication Date
NO20003068D0 NO20003068D0 (no) 2000-06-15
NO20003068L true NO20003068L (no) 2000-06-15
NO317253B1 NO317253B1 (no) 2004-09-27

Family

ID=10823694

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20003068A NO317253B1 (no) 1997-12-16 2000-06-15 Hydrat av 5-[-4-[2-(N-metyl-N-(2-pyridyl)amino)etoksy]benzyl]tiazolidin-2,4-dion-maleinsyre-salt

Country Status (37)

Country Link
US (2) US7045633B2 (no)
EP (1) EP1045847A1 (no)
JP (1) JP2002508372A (no)
KR (1) KR100549143B1 (no)
CN (3) CN1281454A (no)
AP (1) AP1441A (no)
AR (2) AR017213A1 (no)
AU (1) AU2272399A (no)
BG (1) BG64905B1 (no)
BR (1) BR9813604A (no)
CA (1) CA2314965A1 (no)
CO (1) CO4990927A1 (no)
CZ (1) CZ299970B6 (no)
DZ (1) DZ2680A1 (no)
EA (1) EA002355B1 (no)
EG (2) EG21417A (no)
GB (1) GB9726568D0 (no)
HR (1) HRP20000405A2 (no)
HU (1) HUP0100500A3 (no)
ID (1) ID24744A (no)
IL (1) IL136381A (no)
IN (1) IN190821B (no)
MA (1) MA26582A1 (no)
MY (1) MY135770A (no)
NO (1) NO317253B1 (no)
NZ (1) NZ504704A (no)
OA (1) OA11634A (no)
PE (1) PE20000057A1 (no)
PL (1) PL341147A1 (no)
RS (1) RS50079B (no)
SK (1) SK286197B6 (no)
TR (2) TR200001798T2 (no)
TW (1) TW467913B (no)
UA (1) UA63980C2 (no)
UY (2) UY25310A1 (no)
WO (1) WO1999031094A1 (no)
ZA (1) ZA9811505B (no)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9909041D0 (en) * 1999-04-20 1999-06-16 Smithkline Beecham Plc Novel pharmaceutical
KR100744361B1 (ko) * 1999-04-23 2007-07-30 스미스클라인비이참피이엘시이 티아졸리딘디온 유도체 및 항당뇨병제로서 그의 용도
US20040248945A1 (en) 1999-04-23 2004-12-09 Smithkline Beecham P.L.C. Thiazolidinedione derivative and its use as antidiabetic
UA67843C2 (uk) 1999-04-23 2004-07-15 Смітклайн Бічам Плс Поліморф 5-[4-[2-(n-метил-n-(2-піридил)аміно)етокси]бензил]тіазолідин-2,4-діону солі малеїнової кислоти
GB0014005D0 (en) * 2000-06-08 2000-08-02 Smithkline Beecham Plc Novel pharmaceutical
GB0021784D0 (en) * 2000-09-05 2000-10-18 Smithkline Beecham Plc Novel pharmaceutical
GB0021978D0 (en) * 2000-09-07 2000-10-25 Smithkline Beecham Plc Novel pharmaceutical
AU2002350965A1 (en) * 2001-12-13 2003-06-23 Smithkline Beecham Plc Toluenesulfonate hydrates of a thiazolidinedione derivative
WO2003050116A1 (en) * 2001-12-13 2003-06-19 Smithkline Beecham Plc A 5(-4-(2-(n-methyl-n-(2-pyridil)amino)ethoxy)benzyl)thiazolidine-2,4-dione (i) 10-camphorsulphonic acid salt and use against diabetes mellitus
GB0129876D0 (en) * 2001-12-13 2002-02-06 Smithkline Beecham Plc Novel pharmaceutical
GB0130511D0 (en) * 2001-12-20 2002-02-06 Smithkline Beecham Plc Novel pharmaceutical
AU2002352479A1 (en) * 2001-12-20 2003-07-09 Smithkline Beecham Plc 5- (4- (2- (n-methyl-n- (2-pyridyl) amino) ethoxy) benzyl) thiazolidine-2, 4-dione malic acid salt and use against diabetes mellitus
GB2405403A (en) * 2003-08-29 2005-03-02 Cipla Ltd Rosiglitazone maleate of particular polymorphic forms and methods of preparing rosiglitazone free base
ITMI20041537A1 (it) * 2004-07-28 2004-10-28 Chemi Spa Nuova forma polimorfa del rosiglitazone maleato
CZ298424B6 (cs) * 2005-05-24 2007-09-26 Zentiva, A. S. Zpusob krystalizace rosiglitazonu a jeho derivátuze smesných rozpouštedel
EP2184055A1 (en) 2008-11-07 2010-05-12 LEK Pharmaceuticals d.d. Process for preparing solid dosage forms of rosiglitazone maleate

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR240698A1 (es) * 1985-01-19 1990-09-28 Takeda Chemical Industries Ltd Procedimiento para preparar compuestos de 5-(4-(2-(5-etil-2-piridil)-etoxi)benzil)-2,4-tiazolidindiona y sus sales
US4812570A (en) * 1986-07-24 1989-03-14 Takeda Chemical Industries, Ltd. Method for producing thiazolidinedione derivatives
ES2137915T3 (es) 1987-09-04 2000-01-01 Beecham Group Plc Derivados de tiazolidindiona sustituida.
GB8820389D0 (en) * 1988-08-26 1988-09-28 Beecham Group Plc Novel compounds
GB9124513D0 (en) 1991-11-19 1992-01-08 Smithkline Beecham Plc Novel process
AU5082993A (en) 1992-08-28 1994-03-29 Merck & Co., Inc. Cationic-2-heteroarylphenyl-carbapenem antibacterial agents
GB9218830D0 (en) 1992-09-05 1992-10-21 Smithkline Beecham Plc Novel compounds
US5741803A (en) 1992-09-05 1998-04-21 Smithkline Beecham Plc Substituted thiazolidinedionle derivatives
TW245716B (no) * 1992-12-28 1995-04-21 Takeda Pharm Industry Co
DE4404198A1 (de) 1994-02-10 1995-08-17 Henkel Kgaa 2-Fluor-6-nitroaniline
US20020137940A1 (en) 1997-12-16 2002-09-26 Smithkline Beecham P.L.C. 5-[4-[2-(N-methyl-N-(2-pyridyl)amino)ethoxy]benzyl]thiazolidine-2, 4-dione, maleic acid salt, hydrate as pharmaceutical
GB9726566D0 (en) 1997-12-16 1998-02-11 Smithkline Beecham Plc Novel pharmaceutical
US6664278B2 (en) * 1997-12-16 2003-12-16 Smithkline Beecham P.L.C. Hydrate of 5-[4-[2-(N-methyl-N-(2-pyridil)amino)ethoxy]benzyl]thiazolidine-2,4-dione maleic acid salt
GB9726563D0 (en) 1997-12-16 1998-02-11 Smithkline Beecham Plc Novel pharmaceutical
CZ432299A3 (cs) * 1998-06-02 2000-08-16 Smithkline Beecham Plc Kompozice obsahující 5-[4-[2-(N-methyl-N-(2- pyridyI)amino)ethoxy]benzyl]thiazolidin-2,4-dion
KR100744361B1 (ko) 1999-04-23 2007-07-30 스미스클라인비이참피이엘시이 티아졸리딘디온 유도체 및 항당뇨병제로서 그의 용도
UA67843C2 (uk) 1999-04-23 2004-07-15 Смітклайн Бічам Плс Поліморф 5-[4-[2-(n-метил-n-(2-піридил)аміно)етокси]бензил]тіазолідин-2,4-діону солі малеїнової кислоти
TR200103062T2 (tr) 1999-04-23 2002-05-21 Smithkline Beecham P.L.C. Yeni farmasötik maddeler

Also Published As

Publication number Publication date
SK9102000A3 (en) 2001-01-18
IL136381A (en) 2003-09-17
HRP20000405A2 (en) 2000-12-31
KR100549143B1 (ko) 2006-02-03
DZ2680A1 (fr) 2005-02-20
OA11634A (en) 2004-11-22
CN101412714A (zh) 2009-04-22
AU2272399A (en) 1999-07-05
CO4990927A1 (es) 2000-12-26
GB9726568D0 (en) 1998-02-11
CZ299970B6 (cs) 2009-01-07
YU36200A (sh) 2003-12-31
HUP0100500A2 (hu) 2002-05-29
IN190821B (no) 2003-08-23
AP2000001830A0 (en) 2000-06-30
WO1999031094A1 (en) 1999-06-24
MY135770A (en) 2008-06-30
ZA9811505B (en) 2000-11-06
EP1045847A1 (en) 2000-10-25
TR199802626A3 (tr) 1999-10-21
NO317253B1 (no) 2004-09-27
CZ20002205A3 (cs) 2000-11-15
EA200000655A1 (ru) 2000-12-25
CN1281454A (zh) 2001-01-24
NO20003068D0 (no) 2000-06-15
RS50079B (sr) 2009-01-22
EG21417A (en) 2001-10-31
US20060189659A1 (en) 2006-08-24
AR017213A1 (es) 2001-08-22
TR199802626A2 (xx) 1999-10-21
BG104595A (en) 2001-02-28
CN101412713A (zh) 2009-04-22
EG23694A (en) 2007-05-15
US7045633B2 (en) 2006-05-16
PL341147A1 (en) 2001-03-26
AR017430A1 (es) 2001-09-05
NZ504704A (en) 2003-03-28
UY25310A1 (es) 1999-07-19
AP1441A (en) 2005-07-30
CA2314965A1 (en) 1999-06-24
BR9813604A (pt) 2000-10-10
PE20000057A1 (es) 2000-03-09
UA63980C2 (en) 2004-02-16
BG64905B1 (bg) 2006-08-31
JP2002508372A (ja) 2002-03-19
EA002355B1 (ru) 2002-04-25
IL136381A0 (en) 2001-06-14
TR200001798T2 (tr) 2000-11-21
HUP0100500A3 (en) 2002-08-28
UY25305A1 (es) 2000-12-29
SK286197B6 (sk) 2008-05-06
US20040097553A1 (en) 2004-05-20
MA26582A1 (fr) 2004-12-20
KR20010033142A (ko) 2001-04-25
ID24744A (id) 2000-08-03
TW467913B (en) 2001-12-11

Similar Documents

Publication Publication Date Title
NO20003068D0 (no) Hydrat av 5-[-4-[2-(N-metyl-N-(2- pyridyl)amino)etoksy]benzyl]tiazolidin-2,4-dion-maleinsyre-salt
NO2001005I2 (no) 5-Ä4-Ä2-(N-metyl-N-(2-pyridyl)amino)etoksy)benzyl)tiazolidin-2,4dion, maleinsyresalt
MA25658A1 (fr) Sels hydrochlores de 5(4-(2-(n-methyl-n-(2-pyridil) amino) ethoxy) benzyl) thyazolidine-2,4-dione.
AP2000001831A0 (en) 5-[4-[2-(n-methyl-n-(2-pyridyl)amino)ethoxy]benzyl]thiazolidin e-2,4-dione maleic acid salt hydrate as pharmaceutical
DE60004196D1 (de) Polymorph von 5-[4-[2-(n-methyl-n-(2-pyrdyl)amino)äthoxy]benzyl]thiazolidin-2,4-dion, maleinsäuresalz
NO2009002I1 (no) 5-{4-[2-(N-metyl-N-(2-pyridyl)amino)etoksy]benzyl}tiazolidin-2,4-dionmaleat(salter/solvater)+glimepirid
GC0000250A (en) 5-Ä4-Ä2-(N-methyl-n-(2-pyridyl) amino) ethoxyÜ benzylÜthiazolidine-2,4-dione maleci acid salt
NO994209D0 (no) FremgangsmÕte for fremstilling av 2-[[(2-pyridinyl)metyl]sulfinyl]-1H-benzimidazoler og nye forbindelser til anvendelse for dette formÕl
SI1315723T1 (en) The hydrochloride salt of 5(4-(2-(n-methyl-n-(2-pyridyl)amino)ethoxy)benzyl)thiazolidine-2,4-dione
AU2002352386A1 (en) Hydrogensulfate salt of 5-'4-'2-(n-methyl-n-(2-pyridyl)amino)ethoxy!benzyl!thia zolidine-2,4-dione
PL363701A1 (en) Sodium salts of 5-'4-'2-(n-methyl-n-(2-pyridyl)amino)ethoxy]benzyl]thiazolidine-2,4-dione
HK1032955A (en) Hydrate of 5-[4-[2- (n-methyl-n- (2-pyridil)amino) ethoxy]benzyl] thiazolidine-2, 4-dione maleic acid salt
HK1032905A (en) 5-[4-[2-(n-methyl-n-(2-pyridyl)amino) ethoxy]benzyl] thiazolidine-2, 4-dione, maleic acid salt, hydrate as pharmaceutical
HU0700069D0 (en) Acid addition salts of 5-[4-[2-(n-methyl-n-(2-pyridyl)amino)ethoxy]benzyl]thiazolidine-2,4-dione different from malei acid salt
SI1173435T1 (en) Polymorph of 5-(4-(2-(n-methyl-n-(2-pyridyl)amino)ethoxy)benzyl)thiazolidine-2,4-dione maleic acid salt
AU2002222305A1 (en) 5-'4-'2-(n-methyl-n- (2-pyridyl)amino)ethoxy!benzyl!thiazolidine-2, 4-dione mesylate salt
NO20012028L (no) Fremgangsmåte for fremstilling av 4-((2',5'-diamino-6'- halogenpyrimidin-4'-yl)amino)-cyclopent-2-enyl-metanoler

Legal Events

Date Code Title Description
MM1K Lapsed by not paying the annual fees
点击 这是indexloc提供的php浏览器服务，不要输入任何密码和下载