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ME01222B - Nova kombinovana upotreba jedinjenja sulfonamida u liječenju kancera - Google Patents

Nova kombinovana upotreba jedinjenja sulfonamida u liječenju kancera

Info

Publication number
ME01222B
ME01222B MEP-2011-128A MEP12811A ME01222B ME 01222 B ME01222 B ME 01222B ME P12811 A MEP12811 A ME P12811A ME 01222 B ME01222 B ME 01222B
Authority
ME
Montenegro
Prior art keywords
sulfonamide compound
cancer
treatment
combinational use
novel combinational
Prior art date
Application number
MEP-2011-128A
Other languages
English (en)
Inventor
Takashi Tsukuba Res Lab Eisai Co Ltd Owa
Yoichi Tsukuba Res Lab Eisai Co Ltd Ozawa
Taro Tsukuba Res Lab Eisai Co Ltd Semba
T Tsukuba Res Lab Eisai Co Ltd Wakabayashi
Original Assignee
Eisai R&D Man Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eisai R&D Man Co Ltd filed Critical Eisai R&D Man Co Ltd
Publication of ME01222B publication Critical patent/ME01222B/me

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/64—Sulfonylureas, e.g. glibenclamide, tolbutamide, chlorpropamide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/18—Sulfonamides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A61K31/343—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
    • A61K31/381—Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/498—Pyrazines or piperazines ortho- and peri-condensed with carbocyclic ring systems, e.g. quinoxaline, phenazine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/39541—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against normal tissues, cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Farmaceutsko jedinjenje koje uključuje jedinjenje sulfonamida u kombinaciji sa supstancom koja ima EGF inhibitorsku akti vnost, gdje je jedinjenje sulfonamida: N-(3-hloro-1Hindole- 7-yl)-4-sulfamoylbenzensulfonamid,N-(3-cijano-4-metil-1H-indole-7-yl)-3-cijanobenzensulfonamid, ili farmaceutsko prihvatljivu so istog ili njegov rastvor, i gdje je supstanca koja ima EGF inhibitorsku aktivnost gefitinib, erlotinib ili cetuksimab. Patent sadrži još 9 patentnih zahtjeva.
MEP-2011-128A 2005-02-28 2006-02-28 Nova kombinovana upotreba jedinjenja sulfonamida u liječenju kancera ME01222B (me)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2005054111 2005-02-28
PCT/JP2006/304218 WO2006090930A1 (ja) 2005-02-28 2006-02-28 スルホンアミド化合物の新規併用
EP06715261A EP1859793B1 (en) 2005-02-28 2006-02-28 Novel combinational use of a sulfonamide compound in the treatment of cancer

Publications (1)

Publication Number Publication Date
ME01222B true ME01222B (me) 2013-06-20

Family

ID=36927547

Family Applications (1)

Application Number Title Priority Date Filing Date
MEP-2011-128A ME01222B (me) 2005-02-28 2006-02-28 Nova kombinovana upotreba jedinjenja sulfonamida u liječenju kancera

Country Status (18)

Country Link
US (1) US20090047278A1 (me)
EP (1) EP1859793B1 (me)
JP (1) JPWO2006090930A1 (me)
KR (1) KR20070108270A (me)
CN (1) CN101163468A (me)
AU (1) AU2006217692A1 (me)
CA (1) CA2599115A1 (me)
CY (1) CY1111579T1 (me)
DE (1) DE602006021401D1 (me)
DK (1) DK1859793T3 (me)
ES (1) ES2362898T3 (me)
HR (1) HRP20110349T1 (me)
ME (1) ME01222B (me)
PL (1) PL1859793T3 (me)
PT (1) PT1859793E (me)
RS (1) RS51821B (me)
SI (1) SI1859793T1 (me)
WO (1) WO2006090930A1 (me)

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Also Published As

Publication number Publication date
AU2006217692A1 (en) 2006-08-31
DK1859793T3 (da) 2011-08-01
HRP20110349T1 (hr) 2011-07-31
US20090047278A1 (en) 2009-02-19
CA2599115A1 (en) 2006-08-31
DE602006021401D1 (de) 2011-06-01
ES2362898T3 (es) 2011-07-14
WO2006090930A1 (ja) 2006-08-31
JPWO2006090930A1 (ja) 2008-07-24
CN101163468A (zh) 2008-04-16
EP1859793A1 (en) 2007-11-28
PL1859793T3 (pl) 2011-09-30
EP1859793A4 (en) 2008-07-23
CY1111579T1 (el) 2015-10-07
EP1859793B1 (en) 2011-04-20
PT1859793E (pt) 2011-07-05
KR20070108270A (ko) 2007-11-08
SI1859793T1 (sl) 2011-08-31
RS51821B (en) 2012-02-29

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