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Thijs et al., 1986 - Google Patents

Synthesis of the optical antipodes of 4‐alkyl‐γ‐lactones

Thijs et al., 1986

Document ID
3556690711460873516
Author
Thijs L
Waanders P
Stokkingreef E
Zwanenburg B
Publication year
Publication venue
Recueil des Travaux Chimiques des Pays‐Bas

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Snippet

Optical antipodes of 4‐alkyl‐γ‐lactones 3 have been prepared by photochemical rearrangement of optically active α, β‐epoxy diazomethyl ketones 1 in ethanol to give 4‐ hydroxy‐alkenoates 2, followed by reduction of the alkene bond and subsequent …
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    • C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • C07C45/72—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction of compounds containing >C = O groups with the same or other compounds containing >C = O groups
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    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
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