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Chappell et al., 2000 - Google Patents

Synthesis of a six-carbon sialic acid using an indium-mediated coupling

Chappell et al., 2000

Document ID
9553327394277424043
Author
Chappell M
Halcomb R
Publication year
Publication venue
Organic Letters

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The synthesis of a six-carbon truncated sialic acid is described. A key step in the synthesis was an indium-mediated allyl addition to a serine-derived aldehyde. Careful choice of protecting groups was found to be necessary in order to prevent unwanted side reactions …
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