This repository demonstrates an application of the currentscape method to in vivo-like biophysical simulations of hippocampal CA1 neurons. The analysis visualizes how membrane currents distributed across dendritic compartments contribute to somatic activity during simulated place field traversals.

This repository demonstrates an extension of the currentscape method for analyzing the contributions of individual membrane currents to somatic responses in spatially extended biophysical neuron models.

This project simulates synaptic input integration of oblique dendrites in a CA1 pyramidal neuron model.

This project replicates the intracellular current injection experiments from Bittner et al., 2015, Fig. 6a, demonstrating plateau potential initiation in CA1 pyramidal neurons through direct somatic stimulation.

This repository performs automated parameter optimization to maximize calcium Ca2+ influx in the trunk of a CA1 pyramidal neuron model while minimizing calcium influx in oblique dendrites, using the Optuna framework for hyperparameter tuning.