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Haplotype quantification - HLA type prediction and viral lineage quantification from NGS data

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Orthanq

Uncerainty aware haplotype quantification using a Bayesian model that is based on collecting evidences from Varlociraptor.

Orthanq is under active development.

Building for development and manual installation

The easiest way to build Orthanq is via Conda/Mamba. First, create the environment given by the environment.yml in this repository.

mamba env create -n orthanq-dev -f environment.yml

Second, activate the environment with

mamba activate orthanq-dev

Third, build Orthanq via

HDF5_DIR=$CONDA_PREFIX RUSTFLAGS='-L $CONDA_PREFIX/include' cargo build

Last, conda lib location is set via

export LD_LIBRARY_PATH=$CONDA_PREFIX/lib

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Haplotype quantification - HLA type prediction and viral lineage quantification from NGS data

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