ToxPi GitHub 🏡. For current information on ToxPi see: https://toxpi.github.io/
Marvel SW, To K, Grimm FA, Wright FA, Rusyn I, Reif DM. ToxPi Graphical User Interface 2.0: Dynamic exploration, visualization, and sharing of integrated data models. BMC Bioinformatics. 2018. 19(1):80. https://doi.org/10.1186/s12859-018-2089-2
→Direct download of the Stand-alone Java application (GUI) from toxpi.org: toxpi_v2.3.zip
→Direct download the GUI User Manual (PDF) from toxpi.org/Manual: ToxPi User Manual.pdf
R package for the Toxicological Priority Index (ToxPi) prioritization algorithm.
→GitHub for toxpiR package (includes branches under active development with new features): https://github.com/ToxPi/toxpiR
→CRAN version of toxpiR package: https://CRAN.R-project.org/package=toxpiR
Fleming J, Marvel SW, Supak S, Motsinger-Reif AA, Reif DM. ToxPi*GIS Toolkit: creating, viewing, and sharing integrative visualizations for geospatial data using ArcGIS. J Expo Sci Environ Epidemiol. 2022 Apr 26:1–8. https://www.nature.com/articles/s41370-022-00433-w
→Toolkit for integrating ToxPi models with GIS mapping applications
Filer DL, Patisaul HB, Schug T, Reif D, Thayer, K. Test driving ToxCast: endocrine profiling for 1858 chemicals included in phase II. Current Opinion in Pharmacology. 2014. 19:145-152. https://doi.org/10.1016/j.coph.2014.09.021
→Methodological advancement in score calculation used in all subsequent ToxPi implementations
Reif DM, Martin MT, Tan SW, Houck KA, Judson RS, Richard AM, Knudsen TB, Dix DJ, Kavlock RF. Endocrine profiling and prioritization of environmental chemicals using ToxCast data. Environmental Health Perspectives. 2010. 118(12):1714-20. https://doi.org/10.1289/ehp.1002180
→Original publication
Read published uses of the ToxPi framework