Table 2 Potential novel regulators of differentiation in chromaffin cells.

From: RNA-seq of Isolated Chromaffin Cells Highlights the Role of Sex-Linked and Imprinted Genes in Adrenal Medulla Development

Gene symbol

Gene name

Fold Change

Average CPM

FDR

Adrenal Chromaffin Cells

Neuroblasts

Elf3

E74-like factor 3

129.61

70.21

0.53

2.91e-40

Acvrl1

Activin A receptor, type II-like 1

113.65

89.09

0.76

6.47e-43

Gipr

Gastric inhibitory polypeptide receptor

110.20

148.09

1.29

1.77e-56

Casr

Calcium-sensing receptor

77.26

79.92

0.98

1.88e-27

Foxq1

Forkhead box Q1

65.83

191.28

3.10

4.01e-58

Nrk

Nik related kinase

54.92

903.65

16.13

1.78e-11

Baiap3

BAI1-associated protein 3

53.49

426.34

7.87

1.14e-54

Bhlhe40

Basic helix-loop-helix family, member e40

52.96

220.64

4.21

3.50e-54

Gjb5

Gap junction protein, beta 5

50.57

102.94

2.23

9.09e-26

Dapp1

Adaptor for phosphotyrosine and 3-phosphoinositides

35.14

149.67

4.07

1.91e-33

Epha4

Eph receptor A4

33.56

61.58

1.73

2.20e-16

Procr

Protein C receptor, endothelial

31.54

81.68

2.46

3.03e-27

Trim16

Tripartite motif-containing 16

30.46

352.51

11.13

4.53e-56

Gpr139

G protein-coupled receptor 139

29.36

98.63

3.24

7.29e-31

Rgs5

Regulator of G-protein signalling

28.79

705.21

23.35

2.43e-28

Wnt9a

Wnt Family Member 9A

25.10

45.87

1.81

1.81e-24

Dll4

Delta-Like 4 (Drosophila)

21.08

40.86

1.61

3.19e-23

Elf4

E74-like factor 4

14.85

227.91

15.07

2.98e-23

  1. Fold changes and mean expression were obtained using the Bioconductor edgeR package58 with variance between samples by trended estimate. Fold changes is calculated by the gene expression level in adrenal chromaffin precursor cells divided by the gene expression level in sympathetic neuroblasts. Mean expression is reported average count per million (CPM).
Back to article page