News & Media
Welcome to the Calico media center. Please find below features on our R&D efforts as well as our official press releases. For media inquiries, please email press@calicolabs.com.
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Featured Story
April 15, 2020
In 1993, aging science was barely a field of study. Many scientists believed that aging “just happened.” Since aging happens after reproduction, the thinking went, genes for…
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New Analysis Tool Gleans More Insights from Cell Images
Scientists studying aging and disease have long been interested in organelles, the tiny structures inside cells that perform essential functions such as producing … Keep Reading
Investigating Aging in Humans at Population Scale
For decades, scientists have relied on model organisms like mice, fruit flies, and even roundworms to understand the complexities of human biology. These … Keep Reading
PERISCOPE: A Powerful New Tool for Exploring Gene Function
The Human Genome Project laid the foundation for a deep understanding of our genetic code, but it also left scientists with an overwhelming … Keep Reading
Getting a Close-Up Look at Cell Stress
The Integrated Stress Response (ISR) is a conserved signaling pathway across species and an important area of focus for Calico because of its … Keep Reading
Revisiting how HPV Causes Disease
When human papillomavirus (HPV) was first linked to cancer in the early 1980s, it upended the way many biologists thought about viruses and … Keep Reading
Mapping the Mechanisms of Aging
Aging is a universal experience, evident through changes like wrinkles and graying hair. However, aging goes beyond the surface; it begins within our … Keep Reading
Uncovering New Signs of Aging in Blood
By studying DNA data from more than 200,000 research volunteers, scientists at Calico have contributed to a more comprehensive understanding of a key … Keep ReadingProbing the entire genome to pinpoint novel immunotherapy targets
As we grow older, our cells become more prone to damage and mutations, elevating cancer risk. The longer we live, the more chances … Keep Reading
Scientific serendipity yields new insights into cell cycle regulation
Regulation of the cell cycle is of critical importance to the aging process. Proper cell cycle regulation ensures that cells divide when necessary … Keep ReadingPower couple: AI together with Cryo-EM reveals new insights into age-related protein
Answering fundamental questions in biology requires the ability to look closely at the intricate and microscopic world of cells and proteins. At Calico, … Keep Reading
Making the Connection: Environment, Genetics and Implications for Healthy Aging
Uncovering the complex interaction between genetics and the environment and how these two factors shape lifespan, health and disease in humans could help … Keep Reading
Inside the biology of aging: How do scientists tackle a planet-wide diagnosis?
See how the AbbVie-Calico Life Sciences collaboration turns the traditional partnership upside down to tackle age-related diseases. The giant tortoise can roam the … Keep Reading
Improving the ability to predict how DNA sequence influences gene expression
The human genome contains a total of ~3 billion DNA base pairs. An estimated 1-2% of the genome codes for proteins, which influence … Keep Reading
Novel insights from a multiomics dissection of the Hayflick limit
As organisms age, they accumulate cells that no longer function properly but have managed to escape cellular death. These “zombie cells” wreak havoc … Keep Reading
A breakthrough in understanding metabolite regulation of a central stress sensor
Understanding homeostasis in aging and disease could lead to the ability to target specific biological pathways involved in the pathology of disease. That’s … Keep Reading
Understanding cardiometabolic diseases using abdominal MRI scans
Cardiometabolic diseases are an increasing global health burden. And Calico scientists, led by Madeleine Cule, are working with the University of Westminster and … Keep Reading
DCAF15: Understanding how natural killer cells may work
The human immune system can recognize and kill cancer cells growing in the body by sensing mutated proteins on the surface of cancer … Keep Reading
A study in human genetics demonstrates limited influence on longevity
It has been a long-held belief that genetics play a role in lifespan. Calico researchers set out to understand just how much of … Keep Reading
A Broad collaboration
At Calico, we are focused on understanding the biology of aging and age-related diseases and translating our discoveries into potential new therapeutics. In … Keep Reading
Understanding how yeast age
Calico scientists in our yeast biology labs, along with the computing and technology groups, are collaborating closely on a long-term project to invent … Keep Reading
Inventing a new microscope
At Calico, our scientists are not constrained by conventional wisdom. In 2019, scientists Andrew York and Alfred Millett-Sikking believed that there was an … Keep Reading