| Alaska Science Center | Christian Zimmerman | Alaska Region | Alaska |
| Arizona Water Science Center | James Leenhouts | Southwest Region | Arizona |
| Astrogeology Science Center | Chris Okubo (acting) | Southwest Region | Arizona |
| California Water Science Center | Anke Mueller-Solger | Southwest Region | California |
| Caribbean-Florida Water Science Center | Dorothy F Sifuentes, PhD. | Southeast Region | Puerto Rico, Florida |
| Central Energy Resources Science Center | Ofori Pearson | Rocky Mountain Region | Colorado |
| Central Midwest Water Science Center | Amy Beussink | Southeast Region | Illinois, Iowa, Missouri |
| Climate Adaptation Science Centers | National and Regional CASC info | Ecosystems (Mission Area) | Alaska, Arizona, Colorado, Hawaii, Massachusetts, Minnesota, North Carolina, Oklahoma, Virginia, Washington |
| Colorado Water Science Center | Matt Ely | Rocky Mountain Region | Colorado |
| Columbia Environmental Research Center | Kelly Warner | Southeast Region | Missouri |
| Dakota Water Science Center | Eric Volkman | Midcontinent Region | North Dakota, South Dakota |
| Earth Resources Observation and Science Center | Peter Doucette | Core Science Systems (Mission Area) | South Dakota |
| Earthquake Science Center | Christine Goulet | Southwest Region | California |
| Eastern Ecological Science Center | Thomas J O'Connell | Northeast Region | West Virginia, Maryland |
| Florence Bascom Geoscience Center | Christopher Bernhardt | Northeast Region | Virginia |
| Forest and Rangeland Ecosystem Science Center | Sue Phillips | Northwest-Pacific Islands Region | Oregon |
| Fort Collins Science Center | Sharon Taylor | Rocky Mountain Region | Colorado |
| Geologic Hazards Science Center | Ryan Gold | Rocky Mountain Region | Colorado |
| Geology, Energy & Minerals Science Center | Tina Roberts-Ashby | Northeast Region | Virginia |
| Geology, Geophysics, and Geochemistry Science Center | Christopher Moses | Rocky Mountain Region | Colorado |
| Geology, Minerals, Energy, and Geophysics Science Center | Jorge Vazquez (acting) | Southwest Region | California |
| Geosciences and Environmental Change Science Center | Lara Douglas | Rocky Mountain Region | Colorado |
| Great Lakes Science Center | Kurt Newman | Midcontinent Region | Michigan |
| Idaho Water Science Center | Roy Bartholomay | Northwest-Pacific Islands Region | Idaho |
| Kansas Water Science Center | Casey Lee | Midcontinent Region | Kansas |
| Lower Mississippi-Gulf Water Science Center | Rodney Knight | Southeast Region | Alabama, Tennessee, Mississippi, Arkansas, Louisana |
| Maryland-Delaware-D.C. Water Science Center | Mary Kay Foley | Northeast Region | Maryland |
| National Minerals Information Center | Braden Harker | Northeast Region | Virginia |
| National Wildlife Health Center | LeAnn White | Midcontinent Region | Wisconsin |
| Nebraska Water Science Center | Jason Lambrecht (acting) | Midcontinent Region | Nebraska |
| Nevada Water Science Center | Jeff Sanders (acting) | Southwest Region | Nevada |
| New England Water Science Center | Johnathan Bumgarner | Northeast Region | New England, Maine, Vermont, New Hampshire, Rhode Island, Connecticut, Massachusetts |
| New Jersey Water Science Center | Tim Oden | Northeast Region | New Jersey |
| New Mexico Water Science Center | Justin Hagerty | Rocky Mountain Region | New Mexico |
| New York Water Science Center | Robert Francis Breault | Northeast Region | New York |
| Northern Prairie Wildlife Research Center | Robert Gleason | Midcontinent Region | North Dakota |
| Northern Rocky Mountain Science Center (NOROCK) | Claudia Regan | Midcontinent Region | Montana |
| Ohio-Kentucky-Indiana Water Science Center | Jeff Frey | Midcontinent Region | Ohio, Kentucky, Indiana |
| Oklahoma-Texas Water Science Center | Tim Raines | Southeast Region | Oklahoma, Texas |
| Oregon Water Science Center | Joanne Thamke | Northwest-Pacific Islands Region | Oregon |
| Pacific Coastal and Marine Science Center | Peter W. Swarzenski (acting) | Southwest Region | California |
| Pacific Island Ecosystems Research Center | Robert Reed | Northwest-Pacific Islands Region | Hawaii |
| Pacific Islands Water Science Center | John Hoffmann | Northwest-Pacific Islands Region | Hawaii |
| Pennsylvania Water Science Center | Melinda Chapman | Northeast Region | Pennsylvania |
| Science and Decisions Center | Emily J Pindilli | Northeast Region | Virginia |
| South Atlantic Water Science Center | Vic Engel | Southeast Region | Georgia, North Carolina, South Carolina |
| Southwest Biological Science Center | Lew Coggins | Southwest Region | Arizona |
| St. Petersburg Coastal and Marine Science Center | Nathaniel Plant | Southeast Region | Florida |
| Upper Midwest Environmental Sciences Center | Jon Amberg | Midcontinent Region | Wisconsin |
| Upper Midwest Water Science Center | Steven Peterson | Midcontinent Region | Michigan, Wisconsin, Minnesota |
| Utah Water Science Center | David O'Leary | Rocky Mountain Region | Utah |
| Virginia and West Virginia Water Science Center | Mark Bennett | Northeast Region | Virginia |
| Volcano Science Center | Christina Neal | Alaska Region | Alaska, California, Hawaii, California, Nevada, Oregon, and Washington. |
| Washington Water Science Center | Scott VanderKooi | Northwest-Pacific Islands Region | Washington |
| Western Ecological Research Center (WERC) | Matt Dekar | Southwest Region | California |
| Western Fisheries Research Center | Michael Schmidt | Northwest-Pacific Islands Region | Washington |
| Western Geographic Science Center | Susan Benjamin | Southwest Region | California |
| Wetland and Aquatic Research Center | Lynn Copeland | Southeast Region | Florida and Louisiana |
| Woods Hole Coastal and Marine Science Center | Brita Jessen | Northeast Region | Massachusetts |
| Wyoming-Montana Water Science Center | John Kilpatrick | Midcontinent Region | Wyoming, Montana |