We used to support Dtrace on MacOS. However, Apple has changed what they support for dtrace. They removed the -G option that is used to create elf object files that contain probe definitions. The Pony dtrace support is built around creating said object files and linking them in.

I am not an expert on what Apple did, but it appears to be related to SIP and there appear to be ways to add equivalent support but, it also appears to me to be non-trivial.

At the moment, compiling on macos with use=dtrace errors out almost immediately. You can find the dtrace commands that cause the issue by looking for

if(PONY_USE_DTRACE)
    add_custom_command(OUTPUT dtrace_probes.o
        COMMAND dtrace -h -s "${CMAKE_CURRENT_SOURCE_DIR}/../common/dtrace_probes.d" -o "${CMAKE_CURRENT_SOURCE_DIR}/../common/dtrace_probes.h"
        COMMAND dtrace -G -s "${CMAKE_CURRENT_SOURCE_DIR}/../common/dtrace_probes.d" -o dtrace_probes.o
    )
    target_sources(libponyrt PRIVATE dtrace_probes.o)
endif()

in src/libponyrt/CMakeLists.txt.

It is attempting to compile a dtrace_probes.o for the standard runtime dtrace probes.