ZA976725B - Novel pentapeptides as antitumor agents - Google Patents
Novel pentapeptides as antitumor agentsInfo
- Publication number
- ZA976725B ZA976725B ZA976725A ZA976725A ZA976725B ZA 976725 B ZA976725 B ZA 976725B ZA 976725 A ZA976725 A ZA 976725A ZA 976725 A ZA976725 A ZA 976725A ZA 976725 B ZA976725 B ZA 976725B
- Authority
- ZA
- South Africa
- Prior art keywords
- antitumor agents
- pentapeptides
- novel
- novel pentapeptides
- antitumor
- Prior art date
Links
- 239000002246 antineoplastic agent Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/02—Linear peptides containing at least one abnormal peptide link
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Reproductive Health (AREA)
- Pulmonology (AREA)
- Endocrinology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/688,334 US5741892A (en) | 1996-07-30 | 1996-07-30 | Pentapeptides as antitumor agents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA976725B true ZA976725B (en) | 1999-02-12 |
Family
ID=24764016
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA976725A ZA976725B (en) | 1996-07-30 | 1997-07-29 | Novel pentapeptides as antitumor agents |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US5741892A (xx) |
| EP (1) | EP0915908A1 (xx) |
| JP (1) | JP2000516923A (xx) |
| AU (1) | AU3769297A (xx) |
| TW (1) | TW472063B (xx) |
| WO (1) | WO1998004581A1 (xx) |
| ZA (1) | ZA976725B (xx) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1996033212A1 (fr) * | 1995-04-21 | 1996-10-24 | Teikoku Hormone Mfg. Co., Ltd. | Nouveaux derives peptidiques |
| US6323315B1 (en) | 1999-09-10 | 2001-11-27 | Basf Aktiengesellschaft | Dolastatin peptides |
| WO2001024763A2 (en) | 1999-10-01 | 2001-04-12 | Immunogen, Inc. | Compositions and methods for treating cancer using immunoconjugates and chemotherapeutic agents |
| US6884869B2 (en) * | 2001-04-30 | 2005-04-26 | Seattle Genetics, Inc. | Pentapeptide compounds and uses related thereto |
| US7256257B2 (en) | 2001-04-30 | 2007-08-14 | Seattle Genetics, Inc. | Pentapeptide compounds and uses related thereto |
| EP1545613B9 (en) * | 2002-07-31 | 2012-01-25 | Seattle Genetics, Inc. | Auristatin conjugates and their use for treating cancer, an autoimmune disease or an infectious disease |
| SG195524A1 (en) | 2003-11-06 | 2013-12-30 | Seattle Genetics Inc | Monomethylvaline compounds capable of conjugation to ligands |
| RU2254139C1 (ru) * | 2003-11-14 | 2005-06-20 | Российский онкологический научный центр им. Н.Н. Блохина РАМН | Средство, обладающее противоопухолевым действием |
| US7853332B2 (en) * | 2005-04-29 | 2010-12-14 | Medtronic, Inc. | Lead electrode for use in an MRI-safe implantable medical device |
| JP4954983B2 (ja) | 2005-05-18 | 2012-06-20 | ファーマサイエンス・インコーポレイテッド | Ｂｉｒドメイン結合化合物 |
| AU2007250443B2 (en) | 2006-05-16 | 2013-06-13 | Pharmascience Inc. | IAP BIR domain binding compounds |
| ES2528922T3 (es) | 2007-07-16 | 2015-02-13 | Genentech, Inc. | Anticuerpos anti-CD79b humanizados e inmunoconjugados y métodos de uso |
| ES2579323T3 (es) | 2007-07-16 | 2016-08-09 | Genentech, Inc. | Anticuerpos anti-CD79B e inmunoconjugados y métodos de uso |
| AR070168A1 (es) | 2008-01-31 | 2010-03-17 | Genentech Inc | Anticuerpos anti-cd79b e inmunoconjugados y metodos de uso de los mismos |
| SG10201501095WA (en) | 2010-02-12 | 2015-04-29 | Pharmascience Inc | Iap bir domain binding compounds |
| JP6133431B2 (ja) | 2012-11-24 | 2017-05-24 | ハンジョウ ディーエーシー バイオテック シーオー．，エルティディ．Ｈａｎｇｚｈｏｕ Ｄａｃ Ｂｉｏｔｅｃｈ Ｃｏ．，Ｌｔｄ． | 親水性連結体及び薬物分子と細胞結合分子との共役反応における親水性連結体の使用 |
| JP6417421B2 (ja) | 2014-02-28 | 2018-11-07 | ハンジョウ ディーエーシー バイオテック シーオー．，エルティディ．Ｈａｎｇｚｈｏｕ Ｄａｃ Ｂｉｏｔｅｃｈ Ｃｏ．，Ｌｔｄ． | 荷電連結体及び共役体のためのその使用 |
| BR112017023576A2 (pt) | 2014-09-23 | 2023-10-03 | Genentech Inc | Método para tratar uma disfunção proliferativa de células b |
| CN113350518A (zh) | 2015-07-12 | 2021-09-07 | 杭州多禧生物科技有限公司 | 与细胞结合分子的共轭偶联的桥连接体 |
| US9839687B2 (en) | 2015-07-15 | 2017-12-12 | Suzhou M-Conj Biotech Co., Ltd. | Acetylenedicarboxyl linkers and their uses in specific conjugation of a cell-binding molecule |
| KR20220150408A (ko) | 2016-11-14 | 2022-11-10 | 항저우 디에이씨 바이오테크 씨오, 엘티디 | 결합 링커, 그러한 결합 링커를 함유하는 세포 결합 분자-약물 결합체, 링커를 갖는 그러한 결합체의 제조 및 사용 |
| CN116897539A (zh) * | 2021-03-10 | 2023-10-17 | 日本电信电话株式会社 | 信息处理装置、分析方法和程序 |
| EP4400121A1 (en) | 2021-09-03 | 2024-07-17 | Toray Industries, Inc. | Pharmaceutical composition for treating and/or preventing cancer |
| EP4426727A2 (en) | 2021-11-03 | 2024-09-11 | Hangzhou Dac Biotech Co., Ltd. | Specific conjugation of an antibody |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4816444A (en) * | 1987-07-10 | 1989-03-28 | Arizona Board Of Regents, Arizona State University | Cell growth inhibitory substance |
| US4879278A (en) * | 1989-05-16 | 1989-11-07 | Arizona Board Of Regents | Isolation and structural elucidation of the cytostatic linear depsipeptide dolastatin 15 |
| SG87056A1 (en) * | 1991-08-09 | 2002-03-19 | Teikoku Hormone Mfg Co Ltd | Novel tetrapeptide derivative |
| CA2136339C (en) * | 1992-05-20 | 2008-02-05 | Andreas Haupt | Derivatives of dolastatin |
| ATE196296T1 (de) * | 1992-12-16 | 2000-09-15 | Basf Ag | Dolastatin analog |
| US5530097A (en) * | 1994-08-01 | 1996-06-25 | Arizona Board Of Regents Acting On Behalf Of Arizona State University | Human cancer inhibitory peptide amides |
| US5504191A (en) * | 1994-08-01 | 1996-04-02 | Arizona Board Of Regents Acting On Behalf Of Arizona State University | Human cancer inhibitory pentapeptide methyl esters |
| US5663149A (en) * | 1994-12-13 | 1997-09-02 | Arizona Board Of Regents Acting On Behalf Of Arizona State University | Human cancer inhibitory pentapeptide heterocyclic and halophenyl amides |
-
1996
- 1996-07-30 US US08/688,334 patent/US5741892A/en not_active Expired - Fee Related
-
1997
- 1997-07-21 AU AU37692/97A patent/AU3769297A/en not_active Abandoned
- 1997-07-21 WO PCT/EP1997/003902 patent/WO1998004581A1/en not_active Application Discontinuation
- 1997-07-21 JP JP10508458A patent/JP2000516923A/ja active Pending
- 1997-07-21 EP EP97934502A patent/EP0915908A1/en not_active Withdrawn
- 1997-07-29 ZA ZA976725A patent/ZA976725B/xx unknown
- 1997-07-30 TW TW086110885A patent/TW472063B/zh not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| WO1998004581A1 (en) | 1998-02-05 |
| AU3769297A (en) | 1998-02-20 |
| EP0915908A1 (en) | 1999-05-19 |
| US5741892A (en) | 1998-04-21 |
| JP2000516923A (ja) | 2000-12-19 |
| TW472063B (en) | 2002-01-11 |
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