+

WO1996007451A3 - Phototherapeutic apparatus - Google Patents

Phototherapeutic apparatus Download PDF

Info

Publication number
WO1996007451A3
WO1996007451A3 PCT/US1995/011246 US9511246W WO9607451A3 WO 1996007451 A3 WO1996007451 A3 WO 1996007451A3 US 9511246 W US9511246 W US 9511246W WO 9607451 A3 WO9607451 A3 WO 9607451A3
Authority
WO
WIPO (PCT)
Prior art keywords
radiation
tip
disclosed
fiber
length
Prior art date
Application number
PCT/US1995/011246
Other languages
French (fr)
Other versions
WO1996007451A2 (en
Inventor
Edward L Sinofsky
Lincoln S Baxter
Norman Farr
Original Assignee
Rare Earth Med Inc
Edward L Sinofsky
Lincoln S Baxter
Norman Farr
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/468,568 external-priority patent/US5643253A/en
Priority claimed from US08/467,414 external-priority patent/US5632767A/en
Priority claimed from US08/471,744 external-priority patent/US5637877A/en
Application filed by Rare Earth Med Inc, Edward L Sinofsky, Lincoln S Baxter, Norman Farr filed Critical Rare Earth Med Inc
Priority to CA002199384A priority Critical patent/CA2199384C/en
Priority to JP50963496A priority patent/JP3675482B2/en
Priority to KR1019970701608A priority patent/KR970706039A/en
Priority to AU36269/95A priority patent/AU725320B2/en
Priority to EP95933733A priority patent/EP0781154A2/en
Publication of WO1996007451A2 publication Critical patent/WO1996007451A2/en
Publication of WO1996007451A3 publication Critical patent/WO1996007451A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/06—Radiation therapy using light
    • A61N5/0601—Apparatus for use inside the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/06—Radiation therapy using light
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/02—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using physical phenomena
    • A61L2/08—Radiation
    • A61L2/10—Ultraviolet radiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L29/00—Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
    • A61L29/08—Materials for coatings
    • A61L29/085—Macromolecular materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/18—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves
    • A61B18/20—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser
    • A61B18/22—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser the beam being directed along or through a flexible conduit, e.g. an optical fibre; Couplings or hand-pieces therefor
    • A61B2018/2255—Optical elements at the distal end of probe tips
    • A61B2018/2261—Optical elements at the distal end of probe tips with scattering, diffusion or dispersion of light

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Pathology (AREA)
  • Epidemiology (AREA)
  • Radiation-Therapy Devices (AREA)
  • Laser Surgery Devices (AREA)
  • Polarising Elements (AREA)
  • Surgical Instruments (AREA)
  • Harvester Elements (AREA)

Abstract

Optically transmissive fiber tip assemblies having radiation-scattering particles incorporated therein are disclosed for use in phototherapy. In one embodiment, diffusers with reflective end caps are disclosed. As radiation propagates through the fiber tip, a portion of the radiation is scattered in a cylindrical (or partially cylindrical) pattern along the length of the fiber tip. Radiation which is not scattered during this initial pass through the tip can be reflected by at least one surface of the assembly and returned through the tip. During this second pass, the remaining radiation (or at least a major portion of this returning radiation) again encounters the scatterers which provide further radial diffusion of the radiation. The scattering medium and the reflective end cap can interact to provide a substantially uniform (or other predefined) axial distribution of laser radiation over the length of the tip apparatus. In another embodiment, diffusive loop assemblies are disclosed for diffusing radiation from an optical fiber. Disposed sheaths are also disclosed, as are integral stopper devices which limit the penetration of the apparatus. The devices of the invention are useful for various medical purposes as well as the sterilization of medical instruments.
PCT/US1995/011246 1994-09-09 1995-09-08 Phototherapeutic apparatus WO1996007451A2 (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
CA002199384A CA2199384C (en) 1994-09-09 1995-09-08 Phototherapeutic apparatus
JP50963496A JP3675482B2 (en) 1994-09-09 1995-09-08 Phototherapy equipment
KR1019970701608A KR970706039A (en) 1994-09-09 1995-09-08 PHOTOTHERAPEUTIC APPARATUS
AU36269/95A AU725320B2 (en) 1994-09-09 1995-09-08 Phototherapeutic apparatus
EP95933733A EP0781154A2 (en) 1994-09-09 1995-09-08 Phototherapeutic apparatus

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
US30360594A 1994-09-09 1994-09-09
US08/303,605 1994-09-09
US08/468,568 US5643253A (en) 1995-06-06 1995-06-06 Phototherapy apparatus with integral stopper device
US08/467,414 US5632767A (en) 1994-09-09 1995-06-06 Loop diffusers for diffusion of optical radiation
US08/471,744 1995-06-06
US08/471,744 US5637877A (en) 1995-06-06 1995-06-06 Ultraviolet sterilization of instrument lumens
US08/467,414 1995-06-06
US08/468,568 1995-06-06

Publications (2)

Publication Number Publication Date
WO1996007451A2 WO1996007451A2 (en) 1996-03-14
WO1996007451A3 true WO1996007451A3 (en) 1996-05-23

Family

ID=27501834

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1995/011246 WO1996007451A2 (en) 1994-09-09 1995-09-08 Phototherapeutic apparatus

Country Status (7)

Country Link
EP (1) EP0781154A2 (en)
JP (1) JP3675482B2 (en)
KR (1) KR970706039A (en)
CN (1) CN1072971C (en)
AU (1) AU725320B2 (en)
CA (1) CA2199384C (en)
WO (1) WO1996007451A2 (en)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6882875B1 (en) 1997-09-29 2005-04-19 Boston Scientific Corporation Visible display for an interventional device
US7302289B2 (en) 1998-01-20 2007-11-27 Scimed Life Systems, Inc. Readable probe array for in-vivo use
US8109981B2 (en) 2005-01-25 2012-02-07 Valam Corporation Optical therapies and devices
US8900219B2 (en) 1999-07-14 2014-12-02 Cardiofocus, Inc. System and method for visualizing tissue during ablation procedures
US9033961B2 (en) 1999-07-14 2015-05-19 Cardiofocus, Inc. Cardiac ablation catheters for forming overlapping lesions

Families Citing this family (62)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6676656B2 (en) 1994-09-09 2004-01-13 Cardiofocus, Inc. Surgical ablation with radiant energy
US6102905A (en) * 1994-09-09 2000-08-15 Cardiofocus, Inc. Phototherapy device including housing for an optical element and method of making
US6270492B1 (en) 1994-09-09 2001-08-07 Cardiofocus, Inc. Phototherapeutic apparatus with diffusive tip assembly
US6558375B1 (en) * 2000-07-14 2003-05-06 Cardiofocus, Inc. Cardiac ablation instrument
US5947959A (en) * 1994-09-09 1999-09-07 Rare Earth Medical, Inc. Phototherapeutic apparatus with diffusive tip assembly
US6579285B2 (en) 1994-09-09 2003-06-17 Cardiofocus, Inc. Photoablation with infrared radiation
AU718841B2 (en) * 1995-10-31 2000-04-20 Indigo Medical, Incorporated Light-diffusing device for an optical fiber, methods of producing and using same, and apparatus for diffusing light from an optical fiber
US5773835A (en) * 1996-06-07 1998-06-30 Rare Earth Medical, Inc. Fiber optic spectroscopy
JP2001505100A (en) * 1996-11-21 2001-04-17 ボストン サイエンティフィック コーポレイション Mucosal detachment using light
US6200307B1 (en) 1997-05-22 2001-03-13 Illumenex Corporation Treatment of in-stent restenosis using cytotoxic radiation
FR2767704A1 (en) * 1997-09-04 1999-02-26 Medlight Sa LIGHT DIFFUSER DEVICE FOR PHOTODYNAMIC TREATMENT OF ORGANS
US6096030A (en) * 1997-09-23 2000-08-01 Pharmacyclics, Inc. Light delivery catheter and PDT treatment method
US6071302A (en) * 1997-12-31 2000-06-06 Cardiofocus, Inc. Phototherapeutic apparatus for wide-angle diffusion
US6464625B2 (en) * 1999-06-23 2002-10-15 Robert A. Ganz Therapeutic method and apparatus for debilitating or killing microorganisms within the body
US8540704B2 (en) 1999-07-14 2013-09-24 Cardiofocus, Inc. Guided cardiac ablation catheters
AU6616700A (en) 1999-07-30 2001-02-19 Cardiofocus, Inc. Laser method and apparatus for treatment of tissue
DE20003349U1 (en) * 2000-02-24 2000-06-08 Laser & Med Tech Gmbh Device for the thermal treatment of biological tissue
US6551346B2 (en) * 2000-05-17 2003-04-22 Kent Crossley Method and apparatus to prevent infections
HU224941B1 (en) 2001-08-10 2006-04-28 Bgi Innovacios Kft Phototerapy apparatus
EP1478295A2 (en) 2002-02-05 2004-11-24 Pharmacyclics, Inc. Light delivery device using conical diffusing system and method of forming same
US20040092830A1 (en) * 2002-08-05 2004-05-13 Scott Robert W. Catheter and method for diagnosis and treatment of diseased vessels
CA2495562A1 (en) 2002-08-05 2004-02-12 Steven J. Rychnovsky Light delivery catheter
US20050288654A1 (en) * 2004-06-07 2005-12-29 Tim Nieman Methods and devices for delivering ablative energy
DE102006016957B4 (en) * 2006-04-11 2010-04-22 Vimecon Gmbh laser applicator
CN101594827B (en) * 2006-11-30 2012-09-05 学校法人庆应义墪 A device that uses photodynamic therapy (PDT) to block abnormal electrical conduction
US20120095532A1 (en) * 2008-11-03 2012-04-19 David Gertz Device For Irradiating An Internal Body Surface
WO2011105631A1 (en) * 2010-02-26 2011-09-01 学校法人慶應義塾 Catheter performing photodynamic ablation of cardiac muscle tissue by photochemical reaction
JP5486422B2 (en) * 2010-06-28 2014-05-07 株式会社日本ゲルマニウム研究所 Health appliances
EP2683441B1 (en) * 2011-03-11 2016-09-28 Steba Maor SA Focal photodynamic therapy planning methods
CN104415464A (en) * 2013-08-19 2015-03-18 李永皓 Dermatological treatment device, use of laser in treatment of dermatological diseases and disinfection method
JP2015097664A (en) * 2013-11-19 2015-05-28 株式会社アライ・メッドフォトン研究所 Medical device and phototherapeutic apparatus
WO2015080868A1 (en) * 2013-11-26 2015-06-04 Corning Incorporated Anti-bacterial light delivery system and method for disinfecting a surface
WO2015167929A1 (en) 2014-04-28 2015-11-05 Cardiofocus, Inc. System and method for visualizing tissue with an icg dye composition during ablation procedures
JP6303019B2 (en) * 2014-09-19 2018-03-28 シャープ株式会社 Sterilizer
WO2016089900A2 (en) 2014-12-03 2016-06-09 Cardiofocus, Inc. System and method for visual confirmation of pulmonary vein isolation during ablation procedures
KR101661860B1 (en) * 2015-09-24 2016-10-07 동성제약주식회사 The method for manufacturing therapeutic medical device
US11344365B2 (en) 2016-01-05 2022-05-31 Cardiofocus, Inc. Ablation system with automated sweeping ablation energy element
JP6688940B2 (en) * 2016-10-25 2020-04-28 ラクテン メディカル インコーポレイテッド Light diffuser for use in photoimmunotherapy
JP6498654B2 (en) * 2016-11-17 2019-04-10 一般財団法人バイオダイナミックス研究所 Light irradiation probe for light irradiation treatment by endoscope
KR20180061036A (en) * 2016-11-29 2018-06-07 서울바이오시스 주식회사 Liquid bandage hardening device for medical and method for hardening liquid bandage using the same
USD851245S1 (en) 2017-04-14 2019-06-11 Cardiofocus, Inc. Compliant balloon
AU2018297141B2 (en) * 2017-07-07 2020-08-13 Rakuten Medical, Inc. Light diffusing devices for use in photoimmunotherapy
DE102017122756A1 (en) * 2017-09-29 2019-04-04 Schott Ag Lighting system with a light guide with diffuser element
JP7384798B2 (en) 2018-01-15 2023-11-21 カーディオフォーカス，インコーポレーテッド Ablation system using automated ablation energy elements
JP7091453B2 (en) * 2018-06-11 2022-06-27 オリンパス株式会社 Optical connection module for endoscopes, endoscopes, and endoscope systems
CN109009429A (en) * 2018-06-19 2018-12-18 华科精准（北京）医疗科技有限公司 device for laser ablation
WO2020121887A1 (en) * 2018-12-12 2020-06-18 株式会社フジクラ Optical fiber probe
JP7053547B2 (en) * 2019-10-02 2022-04-12 タツタ電線株式会社 Medical light guide and its manufacturing method
CN110893242B (en) * 2019-11-29 2021-02-02 西安交通大学 In-situ ultraviolet sterilization system of in-vivo implanted catheter
CN113017825A (en) * 2019-12-31 2021-06-25 华科精准（北京）医疗科技有限公司 Device for laser interstitial thermotherapy system
US12233173B2 (en) 2020-01-17 2025-02-25 Uv Light Care, Inc. Light-coupling cap sterilization system
US11020502B1 (en) 2020-05-01 2021-06-01 Uv Innovators, Llc Ultraviolet (UV) light emission device, and related methods of use, particularly suited for decontamination
CN112915400A (en) * 2021-03-29 2021-06-08 中国人民解放军空军军医大学 Optical fiber energy gathering device
CN112915399A (en) * 2021-03-29 2021-06-08 中国人民解放军空军军医大学 Optical fiber energy gathering device
US11660359B2 (en) * 2021-04-19 2023-05-30 Varex Imaging Corporation Systems and methods for irradiation
JPWO2022224792A1 (en) * 2021-04-23 2022-10-27
WO2022232479A1 (en) * 2021-04-30 2022-11-03 Bard Access Systems, Inc. Fiber optic disinfection device
WO2023026930A1 (en) 2021-08-27 2023-03-02 古河電気工業株式会社 Irradiation probe
WO2023026988A1 (en) 2021-08-27 2023-03-02 古河電気工業株式会社 Irradiation probe and irradiation probe system
CN114569749A (en) * 2022-03-01 2022-06-03 广东国志激光技术有限公司 Laser disinfection and sterilization device for medical interventional catheter
US12279910B2 (en) 2022-03-22 2025-04-22 Bard Access Systems, Inc. Ultrasound imaging system with a sterilizing system
CN115185020A (en) * 2022-08-04 2022-10-14 江西麦帝施科技有限公司 A kind of diffusion medium and preparation method thereof

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0292621A1 (en) * 1987-05-26 1988-11-30 Surgical Laser Technologies, Inc. Contact or insertion laser probe having wide angle radiation
EP0439629A1 (en) * 1989-08-24 1991-08-07 S.L.T. Japan Co, Ltd. Device for irradiating laser beams
WO1994017434A1 (en) * 1993-01-21 1994-08-04 Fiberguide Industries, Inc. Fiber optic cylindrical diffuser

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4878492A (en) * 1987-10-08 1989-11-07 C. R. Bard, Inc. Laser balloon catheter
ATE117213T1 (en) * 1990-01-09 1995-02-15 Ciba Geigy Ag DEVICE FOR RADIATION OF A PATIENT'S BRONCHIA FOR PHOTODYNAMIC THERAPY.
DK0437183T3 (en) * 1990-01-09 1994-11-21 Ciba Geigy Ag Light diffuser for a photodynamic therapy against tumors in a patient's esophagus

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0292621A1 (en) * 1987-05-26 1988-11-30 Surgical Laser Technologies, Inc. Contact or insertion laser probe having wide angle radiation
EP0439629A1 (en) * 1989-08-24 1991-08-07 S.L.T. Japan Co, Ltd. Device for irradiating laser beams
WO1994017434A1 (en) * 1993-01-21 1994-08-04 Fiberguide Industries, Inc. Fiber optic cylindrical diffuser

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6882875B1 (en) 1997-09-29 2005-04-19 Boston Scientific Corporation Visible display for an interventional device
US7302289B2 (en) 1998-01-20 2007-11-27 Scimed Life Systems, Inc. Readable probe array for in-vivo use
US8900219B2 (en) 1999-07-14 2014-12-02 Cardiofocus, Inc. System and method for visualizing tissue during ablation procedures
US9033961B2 (en) 1999-07-14 2015-05-19 Cardiofocus, Inc. Cardiac ablation catheters for forming overlapping lesions
US9421066B2 (en) 1999-07-14 2016-08-23 Cardiofocus, Inc. System and method for visualizing tissue during ablation procedures
US8109981B2 (en) 2005-01-25 2012-02-07 Valam Corporation Optical therapies and devices

Also Published As

Publication number Publication date
CN1165485A (en) 1997-11-19
KR970706039A (en) 1997-11-03
JPH10504989A (en) 1998-05-19
AU725320B2 (en) 2000-10-12
CN1072971C (en) 2001-10-17
CA2199384C (en) 2006-06-06
EP0781154A2 (en) 1997-07-02
CA2199384A1 (en) 1996-03-14
AU3626995A (en) 1996-03-27
WO1996007451A2 (en) 1996-03-14
JP3675482B2 (en) 2005-07-27

Similar Documents

Publication Publication Date Title
WO1996007451A3 (en) Phototherapeutic apparatus
US6398778B1 (en) Optical fiber diffuser
US5363458A (en) Fiber optic light diffuser
US5637877A (en) Ultraviolet sterilization of instrument lumens
GB2154761A (en) Diffusive optical fibre termination
AU2001290540B2 (en) Photodynamic therapy light diffuser
JP6829780B2 (en) Light diffuser for use in photoimmunotherapy
US5431647A (en) Fiberoptic cylindrical diffuser
US6893432B2 (en) Light-dispersive probe
EP1778118B1 (en) Fiber optic probe for use in a medical device and method of making it
EP0637942B1 (en) Medical device
US5695583A (en) Light diffuser and process for the manufacturing of a light diffuser
US6361530B1 (en) Durable fiber optic diffuser tip and method of making same
US20090210038A1 (en) Medical Light Diffusers for High Power Applications and their Manufacture
US5978541A (en) Custom cylindrical diffusion tips
CN105709338B (en) The system of the irradiation of eyes for live body
AU2001290540A1 (en) Photodynamic therapy light diffuser
US20020028041A1 (en) Wide angle light diffusing optical fiber tip
EP0731931A4 (en) Fiber optic cylindrical diffuser
CA2127361C (en) Cylindrical diffusion tips for optical fibers and method for making
Vesselov et al. Design and performance of thin cylindrical diffusers created in Ge-doped multimode optical fibers
KR970028625A (en) Fiber Connector
US20170340898A1 (en) Source-insensitive cylindrical light diffuser and visual indicator system for phototherapy
AU2018297141B2 (en) Light diffusing devices for use in photoimmunotherapy
WO2000079319A1 (en) Optical fiber diffuser

Legal Events

Date Code Title Description
WWE Wipo information: entry into national phase

Ref document number: 95195954.9

Country of ref document: CN

AK Designated states

Kind code of ref document: A2

Designated state(s): AU CA CN JP KR US US US US

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): AT BE CH DE DK ES FR GB GR IE IT LU MC NL PT SE

DFPE Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101)
121 Ep: the epo has been informed by wipo that ep was designated in this application
ENP Entry into the national phase

Ref document number: 2199384

Country of ref document: CA

Ref document number: 2199384

Country of ref document: CA

Kind code of ref document: A

WWE Wipo information: entry into national phase

Ref document number: 1019970701608

Country of ref document: KR

WWE Wipo information: entry into national phase

Ref document number: 1995933733

Country of ref document: EP

WWP Wipo information: published in national office

Ref document number: 1995933733

Country of ref document: EP

WWP Wipo information: published in national office

Ref document number: 1019970701608

Country of ref document: KR

WWG Wipo information: grant in national office

Ref document number: 1019970701608

Country of ref document: KR

WWR Wipo information: refused in national office

Ref document number: 1995933733

Country of ref document: EP

WWW Wipo information: withdrawn in national office

Ref document number: 1995933733

Country of ref document: EP

点击 这是indexloc提供的php浏览器服务，不要输入任何密码和下载