US20020088470A1 - Method and composition for reducing the tobacco consumption of a human while freshening the breath from tobacco odors - Google Patents
Method and composition for reducing the tobacco consumption of a human while freshening the breath from tobacco odors Download PDFInfo
- Publication number
- US20020088470A1 US20020088470A1 US09/755,031 US75503101A US2002088470A1 US 20020088470 A1 US20020088470 A1 US 20020088470A1 US 75503101 A US75503101 A US 75503101A US 2002088470 A1 US2002088470 A1 US 2002088470A1
- Authority
- US
- United States
- Prior art keywords
- tobacco
- composition
- diminishing
- plantago major
- compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 241000208125 Nicotiana Species 0.000 title claims abstract description 61
- 235000002637 Nicotiana tabacum Nutrition 0.000 title claims abstract description 61
- 239000000203 mixture Substances 0.000 title claims abstract description 32
- 238000000034 method Methods 0.000 title claims abstract description 14
- 235000019645 odor Nutrition 0.000 title description 19
- 244000010922 Plantago major Species 0.000 claims abstract description 25
- 235000015266 Plantago major Nutrition 0.000 claims abstract description 23
- 239000003795 chemical substances by application Substances 0.000 claims abstract description 23
- 230000003467 diminishing effect Effects 0.000 claims abstract description 18
- 239000000654 additive Substances 0.000 claims abstract description 16
- 230000000873 masking effect Effects 0.000 claims abstract description 14
- 230000000996 additive effect Effects 0.000 claims abstract description 13
- 230000003472 neutralizing effect Effects 0.000 claims abstract description 10
- 239000004599 antimicrobial Substances 0.000 claims abstract description 6
- 150000001875 compounds Chemical class 0.000 claims description 12
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 6
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 claims description 6
- 230000001632 homeopathic effect Effects 0.000 claims description 6
- MGSRCZKZVOBKFT-UHFFFAOYSA-N thymol Chemical compound CC(C)C1=CC=C(C)C=C1O MGSRCZKZVOBKFT-UHFFFAOYSA-N 0.000 claims description 6
- 244000024873 Mentha crispa Species 0.000 claims description 5
- 235000014749 Mentha crispa Nutrition 0.000 claims description 5
- 238000002360 preparation method Methods 0.000 claims description 5
- 239000007921 spray Substances 0.000 claims description 5
- 235000001453 Glycyrrhiza echinata Nutrition 0.000 claims description 4
- 235000006200 Glycyrrhiza glabra Nutrition 0.000 claims description 4
- 235000017382 Glycyrrhiza lepidota Nutrition 0.000 claims description 4
- 235000006679 Mentha X verticillata Nutrition 0.000 claims description 4
- 244000246386 Mentha pulegium Species 0.000 claims description 4
- 235000016257 Mentha pulegium Nutrition 0.000 claims description 4
- 235000002899 Mentha suaveolens Nutrition 0.000 claims description 4
- 235000004357 Mentha x piperita Nutrition 0.000 claims description 4
- 235000001636 Mentha x rotundifolia Nutrition 0.000 claims description 4
- 235000001050 hortel pimenta Nutrition 0.000 claims description 4
- 229940010454 licorice Drugs 0.000 claims description 4
- 239000007788 liquid Substances 0.000 claims description 4
- OSWPMRLSEDHDFF-UHFFFAOYSA-N methyl salicylate Chemical compound COC(=O)C1=CC=CC=C1O OSWPMRLSEDHDFF-UHFFFAOYSA-N 0.000 claims description 4
- 241000167854 Bourreria succulenta Species 0.000 claims description 3
- 244000223760 Cinnamomum zeylanicum Species 0.000 claims description 3
- 241000207199 Citrus Species 0.000 claims description 3
- 240000007154 Coffea arabica Species 0.000 claims description 3
- 240000004760 Pimpinella anisum Species 0.000 claims description 3
- 244000223014 Syzygium aromaticum Species 0.000 claims description 3
- 235000016639 Syzygium aromaticum Nutrition 0.000 claims description 3
- 239000005844 Thymol Substances 0.000 claims description 3
- 235000019693 cherries Nutrition 0.000 claims description 3
- 235000017803 cinnamon Nutrition 0.000 claims description 3
- 235000020971 citrus fruits Nutrition 0.000 claims description 3
- 235000016213 coffee Nutrition 0.000 claims description 3
- 235000013353 coffee beverage Nutrition 0.000 claims description 3
- 229960000790 thymol Drugs 0.000 claims description 3
- NOOLISFMXDJSKH-UTLUCORTSA-N (+)-Neomenthol Chemical compound CC(C)[C@@H]1CC[C@@H](C)C[C@@H]1O NOOLISFMXDJSKH-UTLUCORTSA-N 0.000 claims description 2
- WEEGYLXZBRQIMU-UHFFFAOYSA-N 1,8-cineole Natural products C1CC2CCC1(C)OC2(C)C WEEGYLXZBRQIMU-UHFFFAOYSA-N 0.000 claims description 2
- 240000002234 Allium sativum Species 0.000 claims description 2
- BVKZGUZCCUSVTD-UHFFFAOYSA-M Bicarbonate Chemical compound OC([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-M 0.000 claims description 2
- NOOLISFMXDJSKH-UHFFFAOYSA-N DL-menthol Natural products CC(C)C1CCC(C)CC1O NOOLISFMXDJSKH-UHFFFAOYSA-N 0.000 claims description 2
- WEEGYLXZBRQIMU-WAAGHKOSSA-N Eucalyptol Chemical compound C1C[C@H]2CC[C@]1(C)OC2(C)C WEEGYLXZBRQIMU-WAAGHKOSSA-N 0.000 claims description 2
- 229960005233 cineole Drugs 0.000 claims description 2
- 238000000605 extraction Methods 0.000 claims description 2
- 235000004611 garlic Nutrition 0.000 claims description 2
- 229940041616 menthol Drugs 0.000 claims description 2
- 229960001047 methyl salicylate Drugs 0.000 claims description 2
- 150000003839 salts Chemical class 0.000 claims description 2
- 238000003809 water extraction Methods 0.000 claims description 2
- 239000004615 ingredient Substances 0.000 claims 3
- 244000303040 Glycyrrhiza glabra Species 0.000 claims 1
- 239000007787 solid Substances 0.000 claims 1
- 239000008376 breath freshener Substances 0.000 abstract description 4
- 239000000047 product Substances 0.000 description 14
- SNICXCGAKADSCV-JTQLQIEISA-N (-)-Nicotine Chemical compound CN1CCC[C@H]1C1=CC=CN=C1 SNICXCGAKADSCV-JTQLQIEISA-N 0.000 description 9
- SNICXCGAKADSCV-UHFFFAOYSA-N nicotine Natural products CN1CCCC1C1=CC=CN=C1 SNICXCGAKADSCV-UHFFFAOYSA-N 0.000 description 9
- 229960002715 nicotine Drugs 0.000 description 9
- 230000000391 smoking effect Effects 0.000 description 7
- 230000002421 anti-septic effect Effects 0.000 description 6
- 229940074449 plantago major extract Drugs 0.000 description 5
- 244000141009 Hypericum perforatum Species 0.000 description 4
- 235000017309 Hypericum perforatum Nutrition 0.000 description 4
- 235000019504 cigarettes Nutrition 0.000 description 4
- 230000035943 smell Effects 0.000 description 4
- 235000019505 tobacco product Nutrition 0.000 description 4
- 241000894006 Bacteria Species 0.000 description 3
- 241000196324 Embryophyta Species 0.000 description 3
- 241000202807 Glycyrrhiza Species 0.000 description 3
- 230000001430 anti-depressive effect Effects 0.000 description 3
- 229940079593 drug Drugs 0.000 description 3
- 239000003814 drug Substances 0.000 description 3
- 235000019441 ethanol Nutrition 0.000 description 3
- 230000036541 health Effects 0.000 description 3
- 238000002670 nicotine replacement therapy Methods 0.000 description 3
- 229940124535 smoking cessation aid Drugs 0.000 description 3
- 230000002378 acidificating effect Effects 0.000 description 2
- 230000002411 adverse Effects 0.000 description 2
- RJWJHRPNHPHBRN-FKVJWERZSA-N aucubin Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1O[C@H]1[C@@H]2C(CO)=C[C@@H](O)[C@@H]2C=CO1 RJWJHRPNHPHBRN-FKVJWERZSA-N 0.000 description 2
- UTDFQMAXCUGNJR-UHFFFAOYSA-N aucubin Natural products OCC1OC(Oc2ccoc2C3C(O)CCC3O)C(O)C(O)C1O UTDFQMAXCUGNJR-UHFFFAOYSA-N 0.000 description 2
- 230000000747 cardiac effect Effects 0.000 description 2
- 230000001627 detrimental effect Effects 0.000 description 2
- 238000010790 dilution Methods 0.000 description 2
- 239000012895 dilution Substances 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 230000037406 food intake Effects 0.000 description 2
- 238000009472 formulation Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 208000010125 myocardial infarction Diseases 0.000 description 2
- 229930014626 natural product Natural products 0.000 description 2
- 230000004800 psychological effect Effects 0.000 description 2
- 239000000779 smoke Substances 0.000 description 2
- 208000024891 symptom Diseases 0.000 description 2
- VZGDMQKNWNREIO-UHFFFAOYSA-N tetrachloromethane Chemical compound ClC(Cl)(Cl)Cl VZGDMQKNWNREIO-UHFFFAOYSA-N 0.000 description 2
- 230000001225 therapeutic effect Effects 0.000 description 2
- 206010063659 Aversion Diseases 0.000 description 1
- 102000002004 Cytochrome P-450 Enzyme System Human genes 0.000 description 1
- 108010015742 Cytochrome P-450 Enzyme System Proteins 0.000 description 1
- 241000013557 Plantaginaceae Species 0.000 description 1
- 206010049418 Sudden Cardiac Death Diseases 0.000 description 1
- 241001441724 Tetraodontidae Species 0.000 description 1
- 229930013930 alkaloid Natural products 0.000 description 1
- 230000003110 anti-inflammatory effect Effects 0.000 description 1
- 230000002921 anti-spasmodic effect Effects 0.000 description 1
- 229940064004 antiseptic throat preparations Drugs 0.000 description 1
- 230000006399 behavior Effects 0.000 description 1
- 230000003542 behavioural effect Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 239000000872 buffer Substances 0.000 description 1
- 239000006227 byproduct Substances 0.000 description 1
- 150000001720 carbohydrates Chemical class 0.000 description 1
- 235000014633 carbohydrates Nutrition 0.000 description 1
- 230000001684 chronic effect Effects 0.000 description 1
- 238000002485 combustion reaction Methods 0.000 description 1
- 235000015827 common plantain Nutrition 0.000 description 1
- 230000007423 decrease Effects 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 230000007613 environmental effect Effects 0.000 description 1
- 239000000796 flavoring agent Substances 0.000 description 1
- 235000019634 flavors Nutrition 0.000 description 1
- 235000013305 food Nutrition 0.000 description 1
- 235000012631 food intake Nutrition 0.000 description 1
- 229930182470 glycoside Natural products 0.000 description 1
- 150000002338 glycosides Chemical class 0.000 description 1
- 208000019622 heart disease Diseases 0.000 description 1
- 230000005764 inhibitory process Effects 0.000 description 1
- 150000002500 ions Chemical class 0.000 description 1
- 210000004185 liver Anatomy 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- 238000002483 medication Methods 0.000 description 1
- 230000004060 metabolic process Effects 0.000 description 1
- 230000003278 mimic effect Effects 0.000 description 1
- 229930003658 monoterpene Natural products 0.000 description 1
- 235000002577 monoterpenes Nutrition 0.000 description 1
- 239000007922 nasal spray Substances 0.000 description 1
- 238000006386 neutralization reaction Methods 0.000 description 1
- 230000000144 pharmacologic effect Effects 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 230000002028 premature Effects 0.000 description 1
- 230000004224 protection Effects 0.000 description 1
- UMJSCPRVCHMLSP-UHFFFAOYSA-N pyridine Natural products COC1=CC=CN=C1 UMJSCPRVCHMLSP-UHFFFAOYSA-N 0.000 description 1
- JUJWROOIHBZHMG-UHFFFAOYSA-N pyridine Substances C1=CC=NC=C1 JUJWROOIHBZHMG-UHFFFAOYSA-N 0.000 description 1
- -1 pyridine monoterpene alkaloid Chemical class 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
- 230000005586 smoking cessation Effects 0.000 description 1
- 230000003997 social interaction Effects 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
- 231100000816 toxic dose Toxicity 0.000 description 1
- 230000002588 toxic effect Effects 0.000 description 1
- 230000017260 vegetative to reproductive phase transition of meristem Effects 0.000 description 1
- 239000000341 volatile oil Substances 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/68—Plantaginaceae (Plantain Family)
Definitions
- This invention relates to a method and composition for reducing the tobacco consumption of a human while freshening the breath from tobacco odors. More specifically, this invention relates to a composition, containing Plantago major, for reducing tobacco comsumption while diminishing tobacco odors in the mouth.
- NRT Nicotine replacement therapy
- the compound of ‘Cody ' 401 ’ also discloses a smoking cessation aid including the herb Plantago major, but with the addition of Hypericum perforatum .
- the ‘Cody ' 401 ’ composition includes Hypericum perforatum, an anti-depressive, to help with the psychological effects associated with nicotine withdrawal after a tobacco user has ceased consuming nicotine-containing products.
- the disadvantage encountered with this product is the necessity of ingesting an anti-depressive in conjunction with a smoking-cessation aid. Many in the tobacco consuming public might be adverse to the use of an anti-depressive, either due to an aversion to such products or their current use of other medications.
- One object of the invention is therefore to provide a product which reduces the urge for tobacco consumption.
- a further object of the invention is to provide a product which helps diminish the odor which remains in the mouth after consumption of tobacco.
- Another object of the invention is to provide for both an aid for the cessation of tobacco consumption while diminishing the odor left in the mouth after said consumption of tobacco.
- a further object of the invention is to provide for a method of delivering an aid for cessation of tobacco consumption while simultaneously diminishing the odor of the tobacco consumed.
- the present invention provides a composition for reducing tobacco consumption in humans while providing fresh breath comprising Plantago major and an additive for diminishing the odor characteristics of tobacco.
- the additives may be any masking agents, antiseptic agents, neutralizing agents, breath fresheners, mint, licorice, cherry, cinnamon, spearmint, peppermint, anis, garlic, clove, and coffee.
- the present invention also provides a method for reducing the consumption of tobacco while providing fresh breath through the oral administration of a composition comprising Plantago major and an additive for diminishing the odor characteristics of tobacco.
- the present invention provides a composition comprising Plantago major in combination with a tobacco odor diminishing agent for helping consumers of tobacco reduce, or quit, such consumption while diminishing the odor of tobacco during the period of reduction in tobacco consumption.
- the natural product used in the present invention is extracted from the plant Plantago major.
- Plantago major belongs to the Plantaginaceae family and is otherwise know as the ‘common plantain’ or the ‘great plantain.’
- the plant consists of a basal rosette of leaves which abruptly contract into long petioles, and have a cylindrical spike of up to 50 cm in height.
- the extract is derived from the dried leaves of the plant during its flowering period.
- the extraction process may be carried out using any of the commonly known techniques, such as alcohol and/or water extraction.
- the beneficial effects of the Plantago major extract are derived from the compound aucubin, a pyridine monoterpene alkaloid. This particular glycoside has been shown to exhibit efficacy as a suppressant in tobacco consumption. Additionally, aucubin has been shown to include anti-inflammatory and antispasmodic activity as well as protection of the liver against the toxic effects of chemicals such as carbon tetrachloride, possibly due to the inhibition of cytochrome P-450 activity. Plantago major additionally appears to induce a temporary state of relaxation, helping further to mitigate the need for tobacco consumption. Although nicotine has been shown to possess detrimental cardiac effects, Plantago major, to date has not been shown to bring about any adverse cardiac side effects.
- the Plantago major extract of the present invention may be included in a composition meant for oral ingestion.
- the Plantago major extract may be added to the composition of the present invention as a homeopathic preparation.
- Homeopathic preparations are based on the therapeutic approach of administering drugs to a person in need thereof, which would normally bring about symptoms, similar to the disease state, in a healthy person.
- a feature of the homeopathic approach is the administration of the treating composition in very low doses, but sufficient to bring about the desired therapeutic effect.
- a homeopathic remedy may be diluted and rediluted several hundred times. This method of preparing a remedy is called potentization, whereby a remedy is continually diluted to the point of final dilutions which may be 1 part in 1 million.
- the preparations are normally at levels which, at pharmacological or toxic doses, cause symptoms that mimic those which are the subject of the treatment.
- the preparation of Plantago major used in the present invention may then be combined with an additive for diminishing the odor characteristics of tobacco.
- These agents may be, for example, masking agents, neutralizing agents and antiseptic agents.
- Masking agents are primarily used for covering or hiding smells. These agents do not remove smells but compete with the odors found in the mouth. Examples of masking agents include breath fresheners such as mint, licorice, cherry, cinnamon, spearmint, peppermint, anis, cloves and coffee flavorings: either naturally derived or synthetic.
- Antiseptic agents partially correlate with the masking agents due to the antiseptic qualities of some of the masking agents.
- these antiseptics include some of the essential oils of plants such as mint, spearmint, peppermint and licorice as well as alcohol, thymol, menthol, eucalyptol and methyl salicylate.
- Neutralizing agents as opposed to the masking agents, effectively remove smells or the mechanisms which bring about malodor in the mouth. Plaque causing bacteria in the mouth produces malodor due to the acidic byproducts given off through the bacteria's metabolism of carbohydrates. Additionally, residual odor producing molecules are also deposited in the mouth after tobacco consumption and ingestion of certain foods. Agents which assist in the neutralization of acidic conditions brought about by plaque producing bacteria include bicarbonate and effective salts thereof due to their release of neutralizing ions. Citrus flavorings and citric acid also serve to neutralize odors remaining after tobacco or food consumption.
- the combined composition may be formulated into an orally ingestible composition and may be, for example, in liquid form, an orally dissolvable tablet or a powder. If the composition is formulated into a liquid form, it may be delivered to the user through a spray.
- the Plantago major extract in a homeopathic 1 ⁇ (1:10 dilution) is combined into a formulation with water, a pharmaceutically acceptable base, 8% to 10% ethyl alcohol and a predetermined amount of an odor masking, antiseptic or neutralizing agent such as spearmint, citrus flavoring or thymol. Said formulation is then placed into a pressurized spray canister.
- the canister is a commonly know spray dispenser, including a cap which releases the contents upon applied pressure from a finger. In use, a person which orally utilizes or consumes tobacco products may spray the product into the mouth.
- the product may be used as part of a tobacco utilization cessation program and used at specific or regular intervals throughout the day. Alternatively, if the user has reduced their intake of tobacco products they may then use the product only as the need arises.
- the tobacco odor diminishing additive, masking, antiseptic or neutralizing agent of the composition of the present invention is therefore useful to reduce tobacco utilization or consumption as well as mask or neutralize the odor of tobacco or use an antiseptic. As the tobacco use diminishes, the need for the diminishing additive, masking, antiseptic or neutralizing agent also decreases.
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Alternative & Traditional Medicine (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Medical Informatics (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
The present invention provides a composition which is useful for reducing tobacco consumption in humans while providing fresh breath comprising Plantago major and an additive for diminishing the odor of tobacco. The additives may be any breath freshener, masking agents, antiseptic agents and neutralizing agents. The present invention also provides a method for reducing the consumption of tobacco while providing fresh breath through the oral administration of a composition comprising Plantago major and an additive for diminishing the odor of tobacco.
Description
- 1. Field of the Invention
- This invention relates to a method and composition for reducing the tobacco consumption of a human while freshening the breath from tobacco odors. More specifically, this invention relates to a composition, containingPlantago major, for reducing tobacco comsumption while diminishing tobacco odors in the mouth.
- 2. Description of Related Art
- The use of tobacco products has been shown to be a major health risk affecting all age groups and cutting across all socioeconomic levels. According to the American Heart Association, cigarette smoking is the most important preventable cause of premature death in the United States. Smokers' risk of heart attack is more than twice that of nonsmokers. Cigarette smoking is The biggest risk factor for sudden cardiac death: Smokers have two to four times the risk to nonsmokers. Studies have shown cigarette smoking to be an important risk factor for Heart attack Available evidence also indicates that chronic exposure to environmental tobacco smoke (secondhand smoke, passive smoking) may increase the risk of heart disease.
- Studies have also shown that of the estimated 47 million smokers in the United States, more than 32 million report a desire to quit. Nicotine replacement therapy (NRT) has been shown to be safe and effective in helping people stop using cigarettes when used as part of a comprehensive smoking cessation program. NRT medicines are available as gum and patches over-the-counter and as nasal sprays and puffers (“inhalers”) by prescription. The consistent use of one of these products doubles the chances of success with stopping smoking. Behavioral changes and support are essential to success in conjunction with the NRT's and generally, the more intense the behavior modification therapy, the greater the chance of success.
- One such product which may be used for helping in the cessation of tobacco product consumption is disclosed U.S. Pat. No. 4,284,089 entitled Simulated Smoking Device, issued to Jon P. Ray. Ray discloses a simulated smoking device, adapted for non-burning or non-combustion uses and consists of a container defining a passageway having a vaporizable nicotine source therein. As with tobacco consumption, a product, such as the one disclosed in Ray, suffers from its use of nicotine to prevent the need for tobacco.
- Natural products, which may also aid in the reduced consumption of tobacco, have also been proposed. U.S. Pat. No. 5,716,635 entitledPlantago Major Transdermal Patch For Use In Treating A Tobacco Or Nicotine Habit, issued to Mary E. Cody discloses a Plantago major transdermal patch for use in treating a tobacco or nicotine habit. Similarly, U.S. Pat. No. 6,063,401 entitled Plantago Major And Hypericum Perforatum Compound For Use In Treating A Tobacco Or Nicotine Habit, also issued to Mary E. Cody, discloses a Plantago major and Hypericum perforatum compound for us in treating a tobacco or nicotine habit. The difficulty with the transdernal patch proposed by Cody is that the user must wear the patch continually to deliver the necessary amounts of Plantago major extract. This prevents the user from regulating the amount of extract necessary throughout the day.
- The compound of ‘Cody '401’ also discloses a smoking cessation aid including the herb Plantago major, but with the addition of Hypericum perforatum. The ‘Cody '401’ composition includes Hypericum perforatum, an anti-depressive, to help with the psychological effects associated with nicotine withdrawal after a tobacco user has ceased consuming nicotine-containing products. The disadvantage encountered with this product is the necessity of ingesting an anti-depressive in conjunction with a smoking-cessation aid. Many in the tobacco consuming public might be adverse to the use of an anti-depressive, either due to an aversion to such products or their current use of other medications.
- A secondary concern for tobacco consumers, and which may be just as detrimental, is the offensive breath which is commonly evident after tobacco consumption. Not only is the tobacco consumer detrimentally affecting their health, but simultaneously damaging their social interactions due to the offensive odor emitted from their mouths. This additional, psychological effect of tobacco consumption may further compound the health risks encountered by tobacco consumers. In this aspect, it is well know of the large number of breath fresheners available to consumers which attempt to conceal the smell of tobacco. Products which assist in the cessation of tobacco consumption are sometimes formulated with flavored additives, but only for making the product more palatable for the consumer and to cover-up the flavors usually associated with smoking cessation aids.
- In light of the prior art, there currently exists a need for a product which assists tobacco consumers in their fight to reduce their tobacco intake while masking the offensive odor which remains after such tobacco consumption.
- One object of the invention is therefore to provide a product which reduces the urge for tobacco consumption.
- A further object of the invention is to provide a product which helps diminish the odor which remains in the mouth after consumption of tobacco.
- Another object of the invention is to provide for both an aid for the cessation of tobacco consumption while diminishing the odor left in the mouth after said consumption of tobacco.
- A further object of the invention is to provide for a method of delivering an aid for cessation of tobacco consumption while simultaneously diminishing the odor of the tobacco consumed.
- Accordingly, the present invention provides a composition for reducing tobacco consumption in humans while providing fresh breath comprisingPlantago major and an additive for diminishing the odor characteristics of tobacco. The additives may be any masking agents, antiseptic agents, neutralizing agents, breath fresheners, mint, licorice, cherry, cinnamon, spearmint, peppermint, anis, garlic, clove, and coffee.
- The present invention also provides a method for reducing the consumption of tobacco while providing fresh breath through the oral administration of a composition comprisingPlantago major and an additive for diminishing the odor characteristics of tobacco.
- The present invention provides a composition comprisingPlantago major in combination with a tobacco odor diminishing agent for helping consumers of tobacco reduce, or quit, such consumption while diminishing the odor of tobacco during the period of reduction in tobacco consumption.
- The natural product used in the present invention is extracted from the plantPlantago major. Plantago major belongs to the Plantaginaceae family and is otherwise know as the ‘common plantain’ or the ‘great plantain.’ The plant consists of a basal rosette of leaves which abruptly contract into long petioles, and have a cylindrical spike of up to 50 cm in height. The extract is derived from the dried leaves of the plant during its flowering period. The extraction process may be carried out using any of the commonly known techniques, such as alcohol and/or water extraction.
- The beneficial effects of thePlantago major extract are derived from the compound aucubin, a pyridine monoterpene alkaloid. This particular glycoside has been shown to exhibit efficacy as a suppressant in tobacco consumption. Additionally, aucubin has been shown to include anti-inflammatory and antispasmodic activity as well as protection of the liver against the toxic effects of chemicals such as carbon tetrachloride, possibly due to the inhibition of cytochrome P-450 activity. Plantago major additionally appears to induce a temporary state of relaxation, helping further to mitigate the need for tobacco consumption. Although nicotine has been shown to possess detrimental cardiac effects, Plantago major, to date has not been shown to bring about any adverse cardiac side effects.
- ThePlantago major extract of the present invention may be included in a composition meant for oral ingestion. Alternatively, the Plantago major extract may be added to the composition of the present invention as a homeopathic preparation. Homeopathic preparations are based on the therapeutic approach of administering drugs to a person in need thereof, which would normally bring about symptoms, similar to the disease state, in a healthy person. A feature of the homeopathic approach is the administration of the treating composition in very low doses, but sufficient to bring about the desired therapeutic effect.
- A homeopathic remedy may be diluted and rediluted several hundred times. This method of preparing a remedy is called potentization, whereby a remedy is continually diluted to the point of final dilutions which may be 1 part in 1 million. The preparations are normally at levels which, at pharmacological or toxic doses, cause symptoms that mimic those which are the subject of the treatment.
- The preparation ofPlantago major used in the present invention may then be combined with an additive for diminishing the odor characteristics of tobacco. These agents may be, for example, masking agents, neutralizing agents and antiseptic agents. Masking agents are primarily used for covering or hiding smells. These agents do not remove smells but compete with the odors found in the mouth. Examples of masking agents include breath fresheners such as mint, licorice, cherry, cinnamon, spearmint, peppermint, anis, cloves and coffee flavorings: either naturally derived or synthetic.
- Antiseptic agents partially correlate with the masking agents due to the antiseptic qualities of some of the masking agents. Examples of these antiseptics include some of the essential oils of plants such as mint, spearmint, peppermint and licorice as well as alcohol, thymol, menthol, eucalyptol and methyl salicylate.
- Neutralizing agents, as opposed to the masking agents, effectively remove smells or the mechanisms which bring about malodor in the mouth. Plaque causing bacteria in the mouth produces malodor due to the acidic byproducts given off through the bacteria's metabolism of carbohydrates. Additionally, residual odor producing molecules are also deposited in the mouth after tobacco consumption and ingestion of certain foods. Agents which assist in the neutralization of acidic conditions brought about by plaque producing bacteria include bicarbonate and effective salts thereof due to their release of neutralizing ions. Citrus flavorings and citric acid also serve to neutralize odors remaining after tobacco or food consumption.
- The combined composition may be formulated into an orally ingestible composition and may be, for example, in liquid form, an orally dissolvable tablet or a powder. If the composition is formulated into a liquid form, it may be delivered to the user through a spray.
- In a most preferred embodiment, thePlantago major extract, in a homeopathic 1×(1:10 dilution) is combined into a formulation with water, a pharmaceutically acceptable base, 8% to 10% ethyl alcohol and a predetermined amount of an odor masking, antiseptic or neutralizing agent such as spearmint, citrus flavoring or thymol. Said formulation is then placed into a pressurized spray canister. The canister is a commonly know spray dispenser, including a cap which releases the contents upon applied pressure from a finger. In use, a person which orally utilizes or consumes tobacco products may spray the product into the mouth.
- The product may be used as part of a tobacco utilization cessation program and used at specific or regular intervals throughout the day. Alternatively, if the user has reduced their intake of tobacco products they may then use the product only as the need arises. The tobacco odor diminishing additive, masking, antiseptic or neutralizing agent of the composition of the present invention is therefore useful to reduce tobacco utilization or consumption as well as mask or neutralize the odor of tobacco or use an antiseptic. As the tobacco use diminishes, the need for the diminishing additive, masking, antiseptic or neutralizing agent also decreases.
- The foregoing description of a preferred embodiment of the invention has been presented for purposes of illustration and description. It is not intended to be exhaustive or to limit the invention to the precise forms disclosed. Obviously, many modifications and variations will be apparent to practitioners skilled in this art. It is intended that the scope of the invention be defined by the following claims and their equivalents.
Claims (17)
1. An orally administered composition for reducing tobacco consumption, comprising:
a base ingredient;
a predetermined amount of Plantago major; and
a predetermined amount of an additive for diminishing the odor characteristics of tobacco.
2. A composition according to claim 1 , wherein the Plantago major is a homeopathic preparation.
3. A composition according to claim 1 , wherein said additive for diminishing the odor characteristics of tobacco includes a masking agent.
4. A composition according to claim 3 , wherein said masking agent includes one of mint, licorice, cherry, cinnamon, spearmint, peppermint, anis, garlic, cloves and coffee.
5. A composition according to claim 1 , wherein said additive for diminishing the odor characteristics of tobacco includes an antiseptic agent.
6. A composition according to claim 5 , wherein said antiseptic agent includes one of an antiseptically effective amount of alcohol, thymol, menthol, eucalyptol and methyl salicylate.
7. A composition according to claim 1 , wherein said additive for diminishing the odor characteristics of tobacco includes a neutralizing agent.
8. A composition according to claim 7 , wherein said neutralizing agent includes one of bicarbonate or an effective salt thereof, citrus extract and citric acid.
9. A composition according to claim 1 , wherein said base ingredient is in liquid form.
10. A composition according to claim 1 , wherein said base ingredient is in solid form.
11. A method for reducing tobacco consumption of a human, while providing fresh breath, comprising:
preparing a compound comprising Plantago major;
providing an additive for diminishing the odor characteristics of tobacco;
combining said Plantago major and said additive to formulate a composition which diminishes tobacco consumption while diminishing the odor characteristics of tobacco; and
orally administering said composition to a human.
12. A method according to claim 11 , wherein the oral administration is carried out through a spray.
13. A method according to claim 11 , further including formulating said composition into a liquid.
14. A method according to claim 11 , further including forming said composition into an orally dissolvable tablet.
15. A method according to claim 11 , where preparing a compound comprising Plantago major includes preparing said compound homeopathically.
16. A method according to claim 11 , where preparing a compound comprising Plantago major includes preparing said compound through alcohol extraction.
17. A method according to claim 11 , where preparing a compound comprising Plantago major includes preparing said compound through water extraction.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/755,031 US20020088470A1 (en) | 2001-01-08 | 2001-01-08 | Method and composition for reducing the tobacco consumption of a human while freshening the breath from tobacco odors |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/755,031 US20020088470A1 (en) | 2001-01-08 | 2001-01-08 | Method and composition for reducing the tobacco consumption of a human while freshening the breath from tobacco odors |
Publications (1)
Publication Number | Publication Date |
---|---|
US20020088470A1 true US20020088470A1 (en) | 2002-07-11 |
Family
ID=25037424
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US09/755,031 Abandoned US20020088470A1 (en) | 2001-01-08 | 2001-01-08 | Method and composition for reducing the tobacco consumption of a human while freshening the breath from tobacco odors |
Country Status (1)
Country | Link |
---|---|
US (1) | US20020088470A1 (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20050189164A1 (en) * | 2004-02-26 | 2005-09-01 | Chang Chi L. | Speaker enclosure having outer flared tube |
-
2001
- 2001-01-08 US US09/755,031 patent/US20020088470A1/en not_active Abandoned
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20050189164A1 (en) * | 2004-02-26 | 2005-09-01 | Chang Chi L. | Speaker enclosure having outer flared tube |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CA2914089C (en) | Nicotine-containing liquid formulations and uses thereof | |
AU2003243074B2 (en) | A buffered, liquid nicotine composition for pulmonary administration | |
US7767698B2 (en) | Formulation and use thereof | |
US6790465B2 (en) | Composition and method for treating snoring | |
US20050042172A1 (en) | Administration of medicaments by vaporisation | |
CN100506241C (en) | Smoking cessation healthcare product and preparation method thereof | |
JP2012517402A (en) | Composition for buccal absorption of nicotine for smoking cessation | |
US6045825A (en) | Plantago major and Piper methysticum compound for use in treating a tobacco or nicotine habit | |
US20050100513A1 (en) | Homeopathic method and system for treating nicotine addiction | |
US5716635A (en) | Plantago major transdermal patch for use in treating a tobacco or nicotine habit | |
EP2029098A2 (en) | Smoking withdrawal combination wafer | |
CN101249130B (en) | Medicinal or health care combination for stop smoking or alleviating stop smoking syndrome | |
US20020088470A1 (en) | Method and composition for reducing the tobacco consumption of a human while freshening the breath from tobacco odors | |
CN1961763B (en) | Cigarette made from rosemary herb | |
Suchita et al. | HERBAL INHALATION PODS FOR NASAL DECONGESTION. | |
KR101126279B1 (en) | Composition of mixed essential oils which is effective for stop smoking and its utiliztion | |
KR100370390B1 (en) | Composition for inducing prohibition of smoking comprising alkaloids from Radix ipecauanhae | |
CN107713004A (en) | A kind of smoking abstention method | |
JP2022169855A (en) | Frequent urination improver | |
WO2023096535A1 (en) | Smoking cessation agent | |
WO2024188185A1 (en) | Oral spray composition, preparation method therefor, and ultrasonic atomization system | |
TWI484958B (en) | A composition for buccal absorption of nicotine for the purpose of smoking cessation | |
US8399031B1 (en) | Compositions and methods for restoring pulmonary function | |
Salama | El-Darier, Habiba A. El-Zohary, Zeinab A. Farghly, Yara E. Wahba, El-Nagi F. Abdelhady, Roufaida M. Elghobashy (2023) | |
WO2015068058A1 (en) | Tobacco free 'niconuts'and the process thereof |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
STCB | Information on status: application discontinuation |
Free format text: ABANDONED -- FAILURE TO RESPOND TO AN OFFICE ACTION |